List of works - Donald Y M Leung

A phase II, randomized, double‑blind, parallel‑group, placebo‑controlled oral food challenge trial of Xolair (omalizumab) in peanut allergy

scientific article

Advances in atopic dermatitis

scientific article

Air pollutants contribute to epithelial barrier dysfunction and allergic diseases

scientific article published in 2024

Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma

scientific article

Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis.

scientific article published on February 2017

Atopic dermatitis and asthma: parallels in the evolution of treatment

scientific article

Cluster Analysis of Obesity and Asthma Phenotypes ⬇️

scientific article (publication date: 2012)

Crystal structure of the streptococcal superantigen SpeI and functional role of a novel loop domain in T cell activation by group V superantigens

scientific article

Deciphering the complexities of atopic dermatitis: shifting paradigms in treatment approaches

scientific article

Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use

scientific article

Developing drugs for treatment of atopic dermatitis in children (≥3 months to <18 years of age): Draft guidance for industry

scientific article published on 30 March 2018

Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report

scientific article published on July 2006

Effect of anti-IgE therapy in patients with peanut allergy

scientific article (publication date: 13 March 2003)

Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum.

scientific article published on September 2009

Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin–induced keratinocyte death ⬇️

scientific article published on December 11, 2012

Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation

scientific journal article

Genetic Variants in Interferon Regulatory Factor 2 (IRF2) Are Associated with Atopic Dermatitis and Eczema Herpeticum ⬇️

scientific article published on November 24, 2011

Genetic and epigenetic studies of atopic dermatitis

scientific article

Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum.

scientific article

Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence

scientific article

How does pollution worsen allergies?

scientific article published in 2024

Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response ⬇️

scientific article published on April 1, 2011

ICER report for peanut OIT comes up short

scientific article published on 09 September 2019

IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis

scientific article

IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation

scientific article

Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy

scientific article

Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation

scientific article published on 24 September 2007

Increased cis-to-trans urocanic acid ratio in the skin of chronic spontaneous urticaria patients

scientific article

Increased epidermal filaggrin in chronic idiopathic urticaria is associated with severity of urticaria.

scientific article

Increases in plasma IgG4/IgE with trilipid vs paraffin/petrolatum-based emollients for dry skin/eczema

scientific article published on 06 May 2020

Interactions Between Atopic Dermatitis and Staphylococcus aureus Infection: Clinical Implications

scientific article published on 01 September 2019

Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants

scientific article

Mechanisms by Which Atopic Dermatitis Predisposes to Food Allergy and the Atopic March

scientific article published on 01 January 2019

New Approaches for the Treatment of Anaphylaxis

article

New approaches for the treatment of anaphylaxis

scientific article

New era of biologic therapeutics in atopic dermatitis ⬇️

scientific article published on January 16, 2013

Phenotype of atopic dermatitis subjects with a history of eczema herpeticum.

scientific article

Recent insights into atopic dermatitis and implications for management of infectious complications

scientific article

Recombinant interferon gamma therapy for atopic dermatitis

scientific article

Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis

scientific article

Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis

scientific article

Serine-Arginine-rich Protein p30 Directs Alternative Splicing of Glucocorticoid Receptor Pre-mRNA to Glucocorticoid Receptor β in Neutrophils ⬇️

scientific article (publication date: 18 July 2003)

Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities

scientific article published in April 2005

Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum.

scientific article

Temporal and Racial Differences Associated with Atopic Dermatitis Staphylococcusaureus and Encoded Virulence Factors

scientific article

Th2 cytokines increase Staphylococcus aureus alpha toxin-induced keratinocyte death through the signal transducer and activator of transcription 6 (STAT6)

scientific article

The ABC's of managing patients with severe atopic dermatitis ⬇️

scientific article published on August 1, 2013

The effects of airway microbiome on corticosteroid responsiveness in asthma

scientific article

The infectious aspects of atopic dermatitis

scientific article

The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype

scientific article published on 01 February 2019

The role of allergens in asthma.

scientific article

The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections.

scientific article

Tight junction defects in patients with atopic dermatitis.

scientific article

Timing of initial exposure to cereal grains and the risk of wheat allergy

scientific article

Transcutaneous yellow fever vaccination of subjects with or without atopic dermatitis

scientific article published on 10 December 2013

Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response

scientific article published on 17 August 2009

Vaccinia virus-specific molecular signature in atopic dermatitis skin

scientific article

Vitamin D levels, lung function, and steroid response in adult asthma

scientific article

List of works by Donald Y M Leung

A phase II, randomized, double‑blind, parallel‑group, placebo‑controlled oral food challenge trial of Xolair (omalizumab) in peanut allergy

Advances in atopic dermatitis

Air pollutants contribute to epithelial barrier dysfunction and allergic diseases

Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma

Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis.

Atopic dermatitis and asthma: parallels in the evolution of treatment

Cluster Analysis of Obesity and Asthma Phenotypes ⬇️

Crystal structure of the streptococcal superantigen SpeI and functional role of a novel loop domain in T cell activation by group V superantigens

Deciphering the complexities of atopic dermatitis: shifting paradigms in treatment approaches

Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use

Developing drugs for treatment of atopic dermatitis in children (≥3 months to <18 years of age): Draft guidance for industry

Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report

Effect of anti-IgE therapy in patients with peanut allergy

Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum.

Filaggrin-dependent secretion of sphingomyelinase protects against staphylococcal α-toxin–induced keratinocyte death ⬇️

Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation

Genetic Variants in Interferon Regulatory Factor 2 (IRF2) Are Associated with Atopic Dermatitis and Eczema Herpeticum ⬇️

Genetic and epigenetic studies of atopic dermatitis

Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum.

Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence

How does pollution worsen allergies?

Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response ⬇️

ICER report for peanut OIT comes up short

IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis

IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation

Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy

Impaired immune response to vaccinia virus inoculated at the site of cutaneous allergic inflammation

Increased cis-to-trans urocanic acid ratio in the skin of chronic spontaneous urticaria patients

Increased epidermal filaggrin in chronic idiopathic urticaria is associated with severity of urticaria.

Increases in plasma IgG4/IgE with trilipid vs paraffin/petrolatum-based emollients for dry skin/eczema

Interactions Between Atopic Dermatitis and Staphylococcus aureus Infection: Clinical Implications

Maternal consumption of peanut during pregnancy is associated with peanut sensitization in atopic infants

Mechanisms by Which Atopic Dermatitis Predisposes to Food Allergy and the Atopic March

New Approaches for the Treatment of Anaphylaxis

New approaches for the treatment of anaphylaxis

New era of biologic therapeutics in atopic dermatitis ⬇️

Phenotype of atopic dermatitis subjects with a history of eczema herpeticum.

Recent insights into atopic dermatitis and implications for management of infectious complications

Recombinant interferon gamma therapy for atopic dermatitis

Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis

Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis

Serine-Arginine-rich Protein p30 Directs Alternative Splicing of Glucocorticoid Receptor Pre-mRNA to Glucocorticoid Receptor β in Neutrophils ⬇️

Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities

Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum.

Temporal and Racial Differences Associated with Atopic Dermatitis Staphylococcusaureus and Encoded Virulence Factors

Th2 cytokines increase Staphylococcus aureus alpha toxin-induced keratinocyte death through the signal transducer and activator of transcription 6 (STAT6)

The ABC's of managing patients with severe atopic dermatitis ⬇️

The effects of airway microbiome on corticosteroid responsiveness in asthma

The infectious aspects of atopic dermatitis

The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype

The role of allergens in asthma.

The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections.

Tight junction defects in patients with atopic dermatitis.

Timing of initial exposure to cereal grains and the risk of wheat allergy

Transcutaneous yellow fever vaccination of subjects with or without atopic dermatitis

Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response

Vaccinia virus-specific molecular signature in atopic dermatitis skin

Vitamin D levels, lung function, and steroid response in adult asthma