Search filters

List of works by Geraint R. Davies

A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis

scientific article

A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

scientific article published on 05 November 2018

A rapid and sensitive HPLC–MS method for the detection of plasma and cellular rifampicin

scientific article published on 10 July 2007

Accelerating the transition of new tuberculosis drug combinations from Phase II to Phase III trials: New technologies and innovative designs

scientific article published on 09 July 2019

Adaptive clinical trials in tuberculosis: applications, challenges and solutions

scientific article published on June 2015

Adequacy of Rifampin Absorption after Jejunostomy Tube Administration.

scientific article published on March 2016

Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia (ARREST): study protocol for a randomised controlled trial

scientific article published on 18 December 2012

An integrated model of care for neurological infections: the first six years of referrals to a specialist service at a university teaching hospital in Northwest England

scientific article published on 24 September 2015

Assessment of the Efficacy of New Anti-Tuberculosis Drugs

scientific article published on December 2008

Association of variants within the GST and other genes with anti-tubercular agents related toxicity: a systematic review and meta-analysis

article

Bedaquiline kills persistent Mycobacterium tuberculosis with no disease relapse: an in vivo model of a potential cure

scientific article published on 01 June 2019

Biomarkers for tuberculosis disease activity, cure, and relapse

scientific article published in February 2010

Bridging the gap in the fight against tuberculosis

scientific article

CYP genetic variants and toxicity related to anti-tubercular agents: a systematic review and meta-analysis

article

Comparing the efficacy of drug regimens for pulmonary tuberculosis: meta-analysis of endpoints in early phase clinical trials

scientific article published on 10 April 2017

Coping with Africa's increasing tuberculosis burden: are community supervisors an essential component of the DOT strategy? Directly observed therapy

scientific article published in July 1997

Delivery of long-term-injectable agents for TB by lay carers: pragmatic randomised trial

scientific article published on 01 November 2019

Directly observed therapy for tuberculosis in rural South Africa, 1991 through 1994

article

Doubts about DOTS.

scientific article published on 4 February 2008

Early clinical development of anti-tuberculosis drugs: science, statistics and sterilizing activity

scientific article published on 10 April 2010

Effects of dosage, comorbidities, and food on isoniazid pharmacokinetics in Peruvian tuberculosis patients

scientific article

Efficacy and Safety of High-Dose Rifampin in Pulmonary Tuberculosis. A Randomized Controlled Trial

scientific article published on 01 September 2018

Efficacy of twice weekly treatment for tuberculosis given under direct observation in Africa

scientific article published on 01 January 1997

Emergence of multidrug-resistant tuberculosis in a community-based directly observed treatment programme in rural South Africa.

scientific article

Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): study protocol for a randomized controlled trial

scientific article

Evaluation of new antituberculosis drugs in mouse models

scientific article published on January 2007

Fluoroquinolones for treating tuberculosis (presumed drug-sensitive)

scientific article

Frequency of functional drug disposition gene polymorphism in Thai population: relevance to antiretroviral drugs

article

Genetic Determinants of the Pharmacokinetic Variability of Rifampin in Malawian Adults with Pulmonary Tuberculosis

scientific article

HIV and tuberculosis

scientific article published on 01 January 1996

High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

scientific article

Impact of the human immunodeficiency virus epidemic on mortality among adults with tuberculosis in rural South Africa, 1991-1995.

scientific article published in November 1998

Importance of collection tube during clinical studies of oseltamivir

scientific article published on 26 February 2007

In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis.

scientific article published on 7 February 2012

Influence of genetic variants on toxicity to anti-tubercular agents: a systematic review and meta-analysis (protocol)

scientific article

Insufficient evidence for chest CT scan in TB outbreak investigation

scientific article published in July 2010

Intra-individual effects of food upon the pharmacokinetics of rifampicin and isoniazid

scientific article published on 01 February 2019

Intrapulmonary pharmacokinetics of first-line anti-TB drugs in Malawian tuberculosis patients

scientific article published on 28 August 2020

Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell Mouse Model

scientific article published on 23 May 2016

Isoniazid activity is terminated by bacterial persistence

scientific article published on 01 June 2007

Kinetics of Mycobacterium tuberculosis-specific IFN-γ responses and sputum bacillary clearance in HIV-infected adults during treatment of pulmonary tuberculosis

scientific article published on 28 May 2015

Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation.

scientific article

Longitudinal Pharmacokinetic-Pharmacodynamic Biomarkers Correlate With Treatment Outcome in Drug-Sensitive Pulmonary Tuberculosis: A Population Pharmacokinetic-Pharmacodynamic Analysis

scientific article published on 06 June 2020

Making up the difference: ensuring the bioequivalence of fixed-dose combinations for tuberculosis

scientific article published on 01 May 2018

Methods for selecting regimen duration to prevent relapse in drug-susceptible and drug-resistant TB.

scientific article

Mixture analysis of tuberculin survey data from northern Malawi and critique of the method.

scientific article

Model-Based Relationship between the Molecular Bacterial Load Assay and Time to Positivity in Liquid Culture

scientific article published on 23 September 2019

Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in rural Africa

scientific article

Mouse models of Japanese encephalitis virus infection: A systematic review and meta-analysis using a meta-regression approach

scientific article published in 2022

Moxifloxacin replacement in contemporary tuberculosis drug regimens is ineffective against persistent Mycobacterium tuberculosis: Novel insights from the Cornell mouse model.

scientific article published on 16 April 2018

Opinion: the pharmacometrics of infectious disease

scientific article published on 28 August 2013

Optimal doses of rifampicin in the standard drug regimen to shorten tuberculosis treatment duration and reduce relapse by eradicating persistent bacteria

scientific article published on 12 December 2017

Optimal sampling strategies for early pharmacodynamic measures in tuberculosis

scientific article published on 19 July 2006

Optimising molecular diagnostic capacity for effective control of tuberculosis in high-burden settings

scientific article published on August 2016

Optimizing outpatient serial sputum colony counting for studies of tuberculosis treatment in resource-poor settings

scientific article

Pediatric tuberculosis in rural South Africa--value of directly observed therapy

scientific article published in October 1998

Perceptions of Research Bronchoscopy in Malawian Adults with Pulmonary Tuberculosis: A Cross-Sectional Study

scientific article published on 28 October 2016

Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis

scientific article published on 16 March 2015

Pharmacokinetics and pharmacodynamics in the development of anti-tuberculosis drugs

scientific article published on August 2008

Pharmacokinetics of anti-TB drugs in Malawian children: reconsidering the role of ethambutol

scientific article published on 10 March 2015

Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso

scientific article

Pharmacokinetics of rifampin in Peruvian tuberculosis patients with and without comorbid diabetes or HIV

scientific article

Pharmacologic considerations in use and development of antituberculosis drugs

scientific article

Poor outcomes in recurrent tuberculosis: More than just drug resistance?

scientific article published on 06 May 2019

Population pharmacokinetic modelling of once-daily ritonavir-boosted darunavir in HIV-infected patients.

scientific article published on 8 November 2010

Population pharmacokinetics of ritonavir-boosted atazanavir in HIV-infected patients and healthy volunteers

scientific article published on 28 March 2009

Protocol for the development of the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline: checklist of items for reporting pharmacogenetic studies

scientific article published on 11 July 2019

Publisher Correction: A patient-level pooled analysis of treatment-shortening regimens for drug-susceptible pulmonary tuberculosis

scientific article published on 01 January 2019

Rapid degradation of oseltamivir phosphate in clinical samples by plasma esterases

scientific article

Re-growth of Mycobacterium tuberculosis populations exposed to antibiotic combinations is due to the presence of isoniazid and not bacterial growth rate

scientific article published on 16 September 2019

Recent advances in tuberculosis: New drugs and treatment regimens.

scientific article published on June 2013

Reply to "adequate design of pharmacokinetic-pharmacodynamic studies will help optimize tuberculosis treatment for the future".

scientific article published in April 2015

Reply to te Brake : Conflicting Findings on an Intermediate Dose of Rifampicin for Pulmonary Tuberculosis

scientific article published on 01 May 2019

Reported outcomes in phase II studies of newly-diagnosed pulmonary tuberculosis

scientific article published on 29 May 2015

Resistance to antituberculosis drugs in rural South Africa: rates, patterns, risks, and transmission dynamics

scientific article published on November 1996

STrengthening the Reporting Of Pharmacogenetic Studies: Development of the STROPS guideline

scientific article published on 21 September 2020

Sales of over-the-counter remedies as an early warning system for winter bed crises

scientific article published on August 1, 2003

Sequential population pharmacokinetic modeling of lopinavir and ritonavir in healthy volunteers and assessment of different dosing strategies

scientific article

Serial image analysis of Mycobacterium tuberculosis colony growth reveals a persistent subpopulation in sputum during treatment of pulmonary TB

scientific article published on 23 March 2016

TB control programmes remain an important gateway to HIV diagnosis in the era of expanded access to HIV care

scientific article published on 01 January 2020

TST positivity in household contacts of tuberculosis patients: a case-contact study in Malawi.

scientific article

The ANC National Health Plan

scientific article published on 01 April 1994

The chemotherapy of tuberculosis: past, present and future [State of the art]

scientific article published on June 1, 2012

The impact of inclusion, dose and duration of pyrazinamide (PZA) on efficacy and safety outcomes in tuberculosis: systematic review and meta-analysis protocol

scientific article published on 17 December 2019

The implications of model-informed drug discovery and development for tuberculosis

scientific article

The increasing burden of tuberculosis in rural South Africa--impact of the HIV epidemic

scientific article published on April 1, 1997

Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay

scientific article published on 30 April 2020

Twice-weekly, directly observed treatment for HIV-infected and uninfected tuberculosis patients: cohort study in rural South Africa

scientific article published on 01 May 1999

Use of nonlinear mixed-effects analysis for improved precision of early pharmacodynamic measures in tuberculosis treatment

scientific article published on September 2006

Vitamin D deficiency in Malawian adults with pulmonary tuberculosis: risk factors and treatment outcomes

scientific article published in August 2015

Who fails to complete tuberculosis treatment? Temporal trends and risk factors for treatment interruption in a community-based directly observed therapy programme in a rural district of South Africa

scientific article published in December 1999