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List of works by Eugenia V Gurevich

Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment

scientific article

Altered sensitivity to rewarding and aversive drugs in mice with inducible disruption of cAMP response element-binding protein function within the nucleus accumbens

article published in 2009

Analyzing the roles of multi-functional proteins in cells: The case of arrestins and GRKs

scientific article

Arrestin makes T cells stop and become active

scientific article published on 6 February 2014

Arrestin mutations: Some cause diseases, others promise cure

scientific article published on 24 October 2018

Arrestin-2 and arrestin-3 differentially modulate locomotor responses and sensitization to amphetamine

scientific article published on 15 April 2017

Arrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding

scientific article

Arrestin-3-Dependent Activation of c-Jun N-Terminal Kinases (JNKs).

scientific article published on 2 March 2015

Arrestin-dependent activation of JNK family kinases

scientific article published on January 2014

Arrestin-mediated signaling: Is there a controversy?

scientific article published on 01 December 2018

Arrestin2 expression selectively increases during neural differentiation

scientific article published on 01 December 2004

Arrestins and G proteins in cellular signaling: The coin has two sides.

scientific article published on 25 September 2018

Arrestins in apoptosis

scientific article published on January 2014

Arrestins regulate cell spreading and motility via focal adhesion dynamics

scientific article

Arrestins: Critical Players in Trafficking of Many GPCRs

scientific article published on 25 March 2015

Arrestins: Introducing Signaling Bias Into Multifunctional Proteins

scientific article published on 06 September 2018

Arrestins: structural disorder creates rich functionality.

scientific article published on 16 February 2018

Arrestins: ubiquitous regulators of cellular signaling pathways

scientific article

Biased GPCR signaling: Possible mechanisms and inherent limitations

scientific article published on 19 March 2020

Biological role of arrestin-1 oligomerization

scientific article published on 17 September 2020

Cleavage of arrestin-3 by caspases attenuates cell death by precluding arrestin-dependent JNK activation

scientific article published on 04 December 2018

Cognitive effects of dopamine depletion in the context of diminished acetylcholine signaling capacity in mice ⬇️

scientific article published on August 3, 2012

Cone arrestin binding to JNK3 and Mdm2: conformational preference and localization of interaction sites

scientific article published on 6 August 2007

Corrigendum to "Biased GPCR signaling: Possible mechanisms and inherent limitations" [Pharmacology & Therapeutics 211 (2020) 107540]

scientific article published on 01 July 2020

Custom-designed proteins as novel therapeutic tools? The case of arrestins

scientific article published on 23 April 2010

Designer adhesion GPCR tells its signaling story

scientific article published on 28 September 2020

Distinct Cellular and Subcellular Distributions of G Protein-Coupled Receptor Kinase and Arrestin Isoforms in the Striatum ⬇️

scientific article published on November 6, 2012

Dopamine depletion and subsequent treatment with L-DOPA, but not the long-lived dopamine agonist pergolide, enhances activity of the Akt pathway in the rat striatum

scientific article

Each rhodopsin molecule binds its own arrestin

scholarly article

Enhanced Mutant Compensates for Defects in Rhodopsin Phosphorylation in the Presence of Endogenous Arrestin-1.

scientific article

Enhanced arrestin facilitates recovery and protects rods lacking rhodopsin phosphorylation

scientific article published on 9 April 2009

Enhanced phosphorylation-independent arrestins and gene therapy

scientific article published on January 2014

Extensive shape shifting underlies functional versatility of arrestins

scientific article

G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).

scientific article published on 13 March 2015

G protein-coupled receptor kinases as regulators of dopamine receptor functions

scientific article published on 10 May 2016

G protein-coupled receptor kinases: from molecules to diseases.

scientific article published in February 2015

G protein-coupled receptor kinases: more than just kinases and not only for GPCRs

scientific article published on 26 August 2011

GPCR Signaling Regulation: The Role of GRKs and Arrestins

GPCR monomers and oligomers: it takes all kinds

scientific article published on 15 January 2008

GPCRs and Signal Transducers: Interaction Stoichiometry

scientific article published on 05 May 2018

GRK3 suppresses L-DOPA-induced dyskinesia in the rat model of Parkinson's disease via its RGS homology domain

scientific article

GRKs as Modulators of Neurotransmitter Receptors

scientific article published on 31 December 2020

Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activation

scientific article published on 04 January 2008

How and why do GPCRs dimerize?

scientific article published on April 2008

Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson's disease

scientific article

Levodopa-induced dyskinesia in MPTP-treated macaques is not dependent on the extent and pattern of nigrostrial lesioning.

scientific article published in July 2005

Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions

scientific article published on May 2005

Lysine in the lariat loop of arrestins does not serve as phosphate sensor

scientific article published on 27 June 2020

Mdm2 enhances ligase activity of parkin and facilitates mitophagy

scientific article published on 19 March 2020

Molecular Defects of the Disease-Causing Human Arrestin-1 C147F Mutant

scientific article published in January 2018

Molecular Mechanisms of GPCR Signaling: A Structural Perspective

scientific article published on 24 November 2017

Non-visual arrestins regulate the focal adhesion formation via small GTPases RhoA and Rac1 independently of GPCRs

scientific article published on 10 November 2017

Overexpression of GRK6 rescues L-DOPA-induced signaling abnormalities in the dopamine-depleted striatum of hemiparkinsonian rats.

scientific article

Overview of different mechanisms of arrestin-mediated signaling

scientific article

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

scientific article published on 21 July 2015

Peptide mini-scaffold facilitates JNK3 activation in cells

scientific article published on 12 February 2016

Plethora of functions packed into 45 kDa arrestins: biological implications and possible therapeutic strategies

scientific article published on 17 August 2019

Progressive Reduction of its Expression in Rods Reveals Two Pools of Arrestin-1 in the Outer Segment with Different Roles in Photoresponse Recovery ⬇️

scientific article published on July 26, 2011

RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.

scientific article published in December 2007

Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant

scientific article

Rich tapestry of G protein-coupled receptor signaling and regulatory mechanisms

scientific article published on 30 May 2008

Role of receptor-attached phosphates in binding of visual and non-visual arrestins to G protein-coupled receptors.

scientific article published on 24 January 2012

Sex differences in the activity of signalling pathways and expression of G-protein-coupled receptor kinases in the neonatal ventral hippocampal lesion model of schizophrenia

scientific article

Silent scaffolds: inhibition OF c-Jun N-terminal kinase 3 activity in cell by dominant-negative arrestin-3 mutant

scientific article

Structural basis of arrestin-3 activation and signaling.

scientific article published on 10 November 2017

Structural determinants of arrestin functions

scientific article published on January 2013

Synthetic biology with surgical precision: Targeted reengineering of signaling proteins ⬇️

scientific article published on June 1, 2012

Targeted deletion of one or two copies of the G protein β subunit Gβ5 gene has distinct effects on body weight and behavior in mice ⬇️

scientific article published on July 30, 2011

Targeting arrestin interactions with its partners for therapeutic purposes

scientific article published on 18 December 2019

The finger loop as an activation sensor in arrestin

scientific article published on 06 November 2020

The functional cycle of visual arrestins in photoreceptor cells ⬇️

scientific article published on July 29, 2011

The molecular acrobatics of arrestin activation

scientific article

The nature of the arrestin x receptor complex determines the ultimate fate of the internalized receptor

scientific article published on 13 January 2003

The new face of active receptor bound arrestin attracts new partners

scientific article

The origin and evolution of G protein-coupled receptor kinases

scientific article published on 19 March 2012

The structural basis of arrestin-mediated regulation of G-protein-coupled receptors

scientific article

The structural basis of the arrestin binding to GPCRs

scientific article published on 28 January 2019

Therapeutic potential of small molecules and engineered proteins

scientific article published on January 2014

Ubiquitin Ligase Parkin Promotes Mdm2–Arrestin Interaction but Inhibits Arrestin Ubiquitination ⬇️

scientific article published on April 12, 2011

Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes

scientific article

Unraveling the Mechanism of Dyskinesia One Transcription Factor at a Time

scientific article published in March 2016

Using In Vitro Pull-Down and In-Cell Overexpression Assays to Study Protein Interactions with Arrestin

scientific article published on 01 January 2019

Visual and both non-visual arrestins in their "inactive" conformation bind JNK3 and Mdm2 and relocalize them from the nucleus to the cytoplasm

scientific article published on 31 May 2006

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