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List of works by Klaus Pfizenmaier

A CD40–CD95L fusion protein interferes with CD40L-induced prosurvival signaling and allows membrane CD40L-restricted activation of CD95

scientific article published on 04 August 2006

A Golgi PKD activity reporter reveals a crucial role of PKD in nocodazole-induced Golgi dispersal

scientific article published on 25 April 2009

A Novel Anti-Kv10.1 Nanobody Fused to Single-Chain TRAIL Enhances Apoptosis Induction in Cancer Cells

scientific article published on 14 May 2020

A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death

scientific article

A TNF receptor antagonistic scFv, which is not secreted in mammalian cells, is expressed as a soluble mono- and bivalent scFv derivative in insect cells

scientific article published on October 1997

A bivalent immunoadhesin of the human interferon-gamma receptor is an effective inhibitor of IFN-gamma activity

scientific article published on December 1995

A cellular reporter assay to monitor insulin receptor kinase activity based on STAT 5-dependent luciferase gene expression

scientific article

A humanized tumor necrosis factor receptor 1 (TNFR1)-specific antagonistic antibody for selective inhibition of tumor necrosis factor (TNF) action

scientific article published on 01 April 2008

A mouse bone marrow stromal cell line with skeletal stem cell characteristics to study osteogenesis in vitro and in vivo

scientific article published on 18 February 2014

A new tool for the quantitative analysis of dendritic filopodial motility

scientific article

A single-chain TNF receptor antagonist is an effective inhibitor of TNF mediated cytotoxicity.

scientific article published on February 1995

ATROSAB, a humanized antagonistic anti-tumor necrosis factor receptor one-specific antibody

scientific article published on November 1, 2010

Activation of CD95L fusion protein prodrugs by tumor-associated proteases

scientific article published on 20 October 2006

Activity of soluble OX40 ligand is enhanced by oligomerization and cell surface immobilization

scientific article

Alloreactive and H-2-restricted Lyt 23 cytotoxic T lymphocytes derive from a common pool of antecedent Lyt 123 precursors

scientific article

An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action

scientific article published on 4 September 2013

An optimized antibody-single-chain TRAIL fusion protein for cancer therapy.

scientific article published on 11 April 2016

Analysis of interleukin 2 receptor sites on activated T cells

scientific article published on 01 May 1983

Analysis of lymphokine producing T helper cells at the clonal level

scientific article published on 01 May 1983

Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy

scientific article

Antagonistic TNF receptor one-specific antibody (ATROSAB): receptor binding and in vitro bioactivity

scientific article

Antagonistic control of tumor necrosis factor receptors by protein kinases A and C. Enhancement of TNF receptor synthesis by protein kinase A and transmodulation of receptors by protein kinase C.

scientific article published on September 1989

Antagonists of TNF action: clinical experience and new developments

scientific article published on March 1, 2009

Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis

scientific article published in Scientific Reports

Antibody-mediated inhibition of TNFR1 attenuates disease in a mouse model of multiple sclerosis.

scientific article

Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein

scientific article

Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor

scientific article published on 6 December 2013

Autocrine stimulation of TNF-alpha mRNA expression in HL-60 cells

scientific article published on 01 January 1987

Biological effects of gamma-interferon on human tumor cells: quantity and affinity of cell membrane receptors for gamma-IFN in relation to growth inhibition and induction of HLA-DR expression

scientific article published in July 1985

Both tumor necrosis factor receptors, TNFR60 and TNFR80, are involved in signaling endothelial tissue factor expression by juxtacrine tumor necrosis factor alpha

scientific article published on 01 September 1995

Bruton's tyrosine kinase (Btk) associates with protein kinase C mu

scientific article (publication date: 12 November 1999)

Cell-Mediated Immunity in Lymphocytic Choriomeningitis I. The Specificity of the Cytotoxic T Lymphocytes

scientific article published on April 1, 1976

Cell-mediated allograft responses in vitro. VI. Studies on macrophage-mediated cytotoxicity

scientific article published on 01 December 1975

Cell-mediated immunity to H-2 antigens. Characteristics of the effector cells as detected in the microcytotoxicity assay

scientific article published on 01 June 1976

Characterization of activators and inhibitors of protein kinase C mu.

scientific article published on January 1995

Characterization of different soluble TNF receptor (TNFR80) derivatives: positive influence of the intracellular domain on receptor/ligand interaction and TNF neutralization capacity

scientific article published in June 1996

Cloning and characterization of promoter and 5'-UTR of the NMDA receptor subunit epsilon 2: evidence for alternative splicing of 5'-non-coding exon.

scientific article

Coexpression of the human TNF receptors TR60 and TR80 in insect cells: analysis of receptor complex formation

scientific article published on October 1994

Conference

scientific article published on 01 September 1998

Construction of a bispecific single chain antibody for recruitment of cytotoxic T cells to the tumour stroma associated antigen fibroblast activation protein

scientific article published on December 28, 2001

Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury

scientific article published on 02 April 2019

Cross-talk mechanisms in the development of insulin resistance of skeletal muscle cells palmitate rather than tumour necrosis factor inhibits insulin-dependent protein kinase B (PKB)/Akt stimulation and glucose uptake

scientific article published on November 1999

Cyclophosphamide-sensitive T lymphocytes suppress the in vivo generation of antigen-specific cytotoxic T lymphocytes

scientific article published on February 1, 1977

Death ligands designed to kill: development and application of targeted cancer therapeutics based on proapoptotic TNF family ligands

scientific article published on January 2009

Differential activation of TRAIL-R1 and -2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative

scientific article published on 01 July 2001

Differential gamma-interferon response of human colon carcinoma cells: inhibition of proliferation and modulation of immunogenicity as independent effects of gamma-interferon on tumor cell growth

scientific article published on 01 August 1985

Dissection of the proliferative and differentiative signals controlling murine cytotoxic T lymphocyte responses

scientific article

Downregulation of tumor necrosis factor (TNF) sensitivity via modulation of TNF binding capacity by protein kinase C activators

scientific article published on December 1987

Drosophila protein kinase D is broadly expressed and a fraction localizes to the Golgi compartment

scientific article published on 17 March 2006

Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans

scientific article published on 01 August 2018

EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells

scientific article

Early events during primary activation of T cells: antigen receptor cross-linking and interleukin 1 initiate proliferative response of human T cells

scientific article published on 01 November 1985

Enantioselective synthesis of aliphatic (S)-cyanohydrins in organic solvents using hydroxynitrile lyase from Manihot esculenta

scientific article published on 01 October 1996

Enforced covalent trimerization increases the activity of the TNF ligand family members TRAIL and CD95L

scientific article published on 17 August 2007

Engineering death receptor ligands for cancer therapy

scientific article published on 14 January 2011

Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration

scientific article published on 10 October 2016

Exogenous activation of tumor necrosis factor receptor 2 promotes recovery from sensory and motor disease in a model of multiple sclerosis

scientific article published on 17 June 2019

Expression of complete human IFN-gamma receptor and its extracellular domain in insect cells: purification and characterization of the recombinant proteins.

scientific article published on April 1994

Expression patterns of protein kinase D 3 during mouse development

scientific article

Frequency analysis of cytotoxic T lymphocyte precursors in chimeric mice. Evidence for intrathymic maturation of clonally distinct self-major histocompatibility complex- and allo-major histocompatiblilty complex-restricted virus-specific T cells

scientific article

Fusion of the tissue factor extracellular domain to a tumour stroma specific single-chain fragment variable antibody results in an antigen-specific coagulation-promoting molecule

scientific article published on August 2000

G-PKDrep-live, a genetically encoded FRET reporter to measure PKD activity at the trans-Golgi-network

scientific article

Gamma interferon regulates long terminal repeat-controlled oncogene expression in transformed mouse fibroblasts at the level of mRNA transcription

scientific article

Generation of Cytotoxic T Lymphocytes Against Ly Alloantigen

scientific article published on January 1, 1977

Generation of a FasL-based proapoptotic fusion protein devoid of systemic toxicity due to cell-surface antigen-restricted Activation

scientific article published on 28 May 2003

Generation of human high-affinity antibodies specific for the fibroblast activation protein by guided selection

scientific article

Genetic control of the cytotoxic T cell response to SV40 tumor-associated specific antigen

scientific article published on May 1, 1979

Genetic engineering of death ligands for improvement of therapeutic activity

scientific article published on 01 January 2011

Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells

scientific article published on 10 April 2012

Glycosylation of the human interferon-gamma receptor. N-linked carbohydrates contribute to structural heterogeneity and are required for ligand binding

scientific article published on January 1990

Guided selection of antibody fragments specific for human interferon γ receptor 1 from a human VH- and VL-gene repertoire

scientific article published on 01 January 1998

H-2 restriction as a consequence of intentional priming. Frequency analysis of alloantigen-restricted, trinitrophenyl-specific cytotoxic T lymphocyte precursors within thymocytes of normal mice

scientific article published on June 1981

H-2 restriction as a consequence of intentional priming: T cells of fully allogeneic chimeric mice as well as of normal mice respond to foreign antigens in the context of H-2 determinants not encountered on thymic epithelial cells

scientific article published on December 1, 1980

High affinity human IFN-gamma-binding capacity is encoded by a single receptor gene located in proximity to c-ros on human chromosome region 6q16 to 6q22

scientific article published on 01 August 1988

Human antibody derivatives against the fibroblast activation protein for tumor stroma targeting of carcinomas

scientific article

IFN-gamma receptors on human tumor cells: relationship between receptor ligand interactions and induction of IFN-gamma response

scientific article published on 01 September 1986

IL-2 production in human T lymphotropic virus I-infected leukemic T lymphocytes analyzed by in situ hybridization

scientific article

Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses

scientific article published on October 1990

Identification of potential active-site residues in the hydroxynitrile lyase from Manihot esculenta by site-directed mutagenesis

scientific article published on 01 October 1996

IgG-single-chain TRAIL fusion proteins for tumour therapy.

scientific article published on 17 May 2018

Immuno-LipoTRAIL: Targeted delivery of TRAIL-functionalized liposomal nanoparticles

scientific article published on 7 May 2014

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses

scientific article published on 01 March 1987

Impact of thymus on the generation of immunocompetence and diversity of antigen-specific MHC-restricted cytotoxic T-lymphocyte precursors

scientific article published on January 1981

Improved monovalent TNF receptor 1-selective inhibitor with novel heterodimerizing Fc

scientific article published on 31 March 2019

Improving TNF as a cancer therapeutic: tailor-made TNF fusion proteins with conserved antitumor activity and reduced systemic side effects

scientific article published on July 2009

In vitro activation and substrates of recombinant, baculovirus expressed human protein kinase C mu

scientific article published on 01 March 1996

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

article

In vivo sensitization of T cells to hapten-conjugated syngeneic structures of major histocompatibility complex. I. Effect ofin vitro culture upon generation of cytotoxic T lymphocytes

scientific article published on November 1, 1976

Increased Apoptosis Induction in Hepatocellular Carcinoma by a Novel Tumor-Targeted TRAIL Fusion Protein Combined With Bortezomib

scientific article published on January 8, 2013

Insulin selectively activates STAT5b, but not STAT5a, via a JAK2-independent signalling pathway in Kym-1 rhabdomyosarcoma cells

scientific article published on 01 December 1999

Intralesional application of recombinant human tumor necrosis factor alpha induces local tumor regression in patients with advanced malignancies

scientific article

Intrathymic differentiation of cytotoxic T lymphocyte (CTL) precursors. I. The CTL immunocompetence of peanut agglutinin-positive (cortical) and negative (medullary) Lyt 123 thymocytes

scientific article published on December 1, 1980

Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway

scientific article published on 31 August 2010

Long-term NR2B expression in the cerebellum alters granule cell development and leads to NR2A down-regulation and motor deficits.

scientific article published on November 2004

Lymphocyte adhesion to human endothelial cells induces tissue factor expression via a juxtacrine pathway

scientific article published on 01 March 1995

Lyt-23+ cyclophosphamide-sensitive T cells regulate the activity of an interleukin 2 inhibitor in vivo

scientific article published on August 1981

Mapping of H–2 genes associated with T cell-mediated cytotoxic responses to SV40–tumour-associated specific antigens

scientific article published on August 17, 1978

Mechanisms of TNF resistance: identification of membrane phosphoproteins associated with a dominant resistant phenotype in lymphoid-myeloid somatic cell hybrids.

scientific article

Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells

scientific article published on January 1997

Molecular Cloning and Expression of Human and Rat Tumor Necrosis Factor Receptor Chain (p60) and Its Soluble Derivative, Tumor Necrosis Factor-Binding Protein

scientific article published on December 1, 1990

Molecular cloning of hydroxynitrile lyase from Sorghum bicolor (L.). Homologies to serine carboxypeptidases

scientific article published in October 1994

Monitoring of scFv selected by phage display using detection of scFv-pIII fusion proteins in a microtiter scale assay

scientific article

Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity

scientific article published on 02 October 2018

Murine T cell subsets and interleukins: relationships between cytotoxic T cells, helper T cells and accessory cells

scientific article published on October 1, 1982

Murine gamma interferon inhibits v-mos-induced fibroblast transformation via down regulation of retroviral gene expression

scientific article published on August 1987

N-glycosidase treatment of Colo 205 cells interferes with hIFN-gamma induced HLA-DR expression

Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2.

scientific article published on 25 March 2002

Neuroprotective and neurodegenerative effects of the chronic expression of tumor necrosis factor α in the nigrostriatal dopaminergic circuit of adult mice

scientific article

Non-apoptotic Fas signaling.

scientific article

Noncytocidal mechanisms of action of tumor necrosis factor-alpha on human tumor cells: enhancement of HLA gene expression synergistic with interferon-gamma.

scientific article

Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2.

scientific article

OMTX705, a Novel FAP-Targeting ADC demonstrates Activity in Chemotherapy and PD1-Resistant Solid Tumors Models

scientific article published on 11 March 2020

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

scientific article

PKCu is a novel, atypical member of the protein kinase C family

scientific article

PKD is recruited to sites of actin remodelling at the leading edge and negatively regulates cell migration

scholarly article by Tim Eiseler published in August 2007

PMA-responsive 5' flanking sequences of the human TNF gene

scientific article published on 01 January 1989

Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor

scientific article

Phase I study of recombinant human tumor necrosis factor-alpha in patients with advanced malignancies

scientific article

Phospho-specific binding of 14-3-3 proteins to phosphatidylinositol 4-kinase III beta protects from dephosphorylation and stabilizes lipid kinase activity

scientific article

Postnatal development of functional T cell subsets in the mouse: a frequency analysis of mitogen reactive precursors of proliferating, of cytotoxic and of IL 2 producing T cells

scientific article published on 01 July 1985

Potent antitumoral activity of TRAIL through generation of tumor-targeted single-chain fusion proteins.

scientific article

Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma

scientific article published on 12 November 2018

Preferential H-2 association in cytotoxic T cell responses to SV40 tumor-associated specific antigens

scientific article published on 01 April 1980

Preferential expression of tumor necrosis factor receptor 55 (TNF-R55) on human articular chondrocytes: selective transcriptional upregulation of TNF-R75 by proinflammatory cytokines interleukin 1beta, tumor necrosis factor-alpha, and basis fibrobla

scientific article

Primary in vitro sensitization of virus specific cytotoxic T lymphocytes

scientific article published on April 1, 1978

Procaryotic expression of single-chain variable-fragment (scFv) antibodies: secretion in L-form cells of Proteus mirabilis leads to active product and overcomes the limitations of periplasmic expression in Escherichia coli

scientific article

Protein kinase C (PKC)eta-mediated PKC mu activation modulates ERK and JNK signal pathways

scientific article

Protein kinase C [micro] is regulated by the multifunctional chaperon protein p32

scientific article

Protein kinase C mu is negatively regulated by 14-3-3 signal transduction proteins

scientific article (publication date: 2 April 1999)

Protein kinase Cmu downregulation of tumor-necrosis-factor-induced apoptosis correlates with enhanced expression of nuclear-factor-kappaB-dependent protective genes

scientific article published on October 1998

Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin

scientific article

Protein kinase D controls the integrity of Golgi apparatus and the maintenance of dendritic arborization in hippocampal neurons

scientific article

Protein kinase D controls voluntary-running-induced skeletal muscle remodelling

scientific article

Protein kinase D promotes plasticity-induced F-actin stabilization in dendritic spines and regulates memory formation.

scientific article

Protein kinase D regulates cell migration by direct phosphorylation of the cofilin phosphatase slingshot 1 like

scientific article

Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIbeta at the Golgi complex

scientific article

Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis

scientific article

Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases

scientific article

Purification and Characterization of a Novel (R)-Mandelonitrile Lyase from the Fern Phlebodium aureum

scientific article published on 01 December 1995

Quantification and characterization of high-affinity membrane receptors for tumor necrosis factor on human leukemic cell lines

scientific article published on 01 July 1986

Quantitation and characterization of gamma-interferon receptors on human tumor cells

scientific article published on 01 October 1986

Quantitative representation of all T cells committed to develop into cytotoxic effector cells and/or interleukin 2 activity-producing helper cells within murine T lymphocyte subsets

scientific article published on 01 January 1984

Rapid modulation of tumor necrosis factor membrane receptors by activators of protein kinase C

scientific article published on 01 December 1986

Regulation of IFN-gamma-receptor expression in human monocytes by granulocyte-macrophage colony-stimulating factor

scientific article published on November 1990

Regulation of secretory transport by protein kinase D-mediated phosphorylation of the ceramide transfer protein

scientific article

Regulation of the murine NMDA-receptor-subunit NR2C promoter by Sp1 and fushi tarazu factor1 (FTZ-F1) homologues

scientific article published on June 1999

Regulation of tumor necrosis factor gene expression in colorectal adenocarcinoma: in vivo analysis by in situ hybridization

scientific article

Restoration of membrane TNF-like activity by cell surface targeting and matrix metalloproteinase-mediated processing of a TNF prodrug

scientific article

Role of caspases in cytokine-induced barrier breakdown in human brain endothelial cells

scientific article published on 15 August 2012

Selective Blocking of TNF Receptor 1 Attenuates Peritoneal Dialysis Fluid Induced Inflammation of the Peritoneum in Mice

scientific article

Selective Targeting of TNF Receptors as a Novel Therapeutic Approach

scientific article published on 26 May 2020

Selective activation of tumor necrosis factor receptor 2 induces anti-inflammatory responses and alleviates experimental arthritis.

scientific article published on 17 January 2018

Selective inhibition of FLICE-like inhibitory protein expression with small interfering RNA oligonucleotides is sufficient to sensitize tumor cells for TRAIL-induced apoptosis

scientific article published on November 2002

Sensitivity of leukemia cell lines to cytotoxic alkyl-lysophospholipids in relation to O-alkyl cleavage enzyme activities

scientific article published in February 1987

Sequential therapy with recombinant interferons gamma and alpha in patients with unfavorable prognosis of chronic myelocytic leukemia: clinical responsiveness to recombinant IFN-alpha correlates with the degree of receptor down-regulation

scientific article published in February 1989

Shared determinants between virus-infected and trinitrophenyl-conjugated H-2-identical target cells detected in cell-mediated lympholysis

scientific article published on September 1, 1976

Short-term treatment with gamma interferon induces stable reversion of ras-transformed mouse fibroblasts

scientific article

Single-chain TNF, a TNF derivative with enhanced stability and antitumoral activity

scientific article

Species-Crossreactive scFv Against the Tumor Stroma Marker “Fibroblast Activation Protein” Selected by Phage Display From an Immunized FAP−/− Knock-Out Mouse

scientific article published on July 1, 2001

Specific membrane receptors for human interferon-gamma (IFN-gamma).

scientific article

Stable expression of a selectable myeloproliferative sarcoma virus in murine T lymphocyte and monocyte cell lines

scientific article

Structural requirements for localization and activation of protein kinase C mu (PKC mu) at the Golgi compartment

scientific article

Superior Properties of Fc-comprising scTRAIL Fusion Proteins

scientific article published on 13 September 2017

Superior Treg-Expanding Properties of a Novel Dual-Acting Cytokine Fusion Protein

scientific article published on 18 December 2019

Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity

scientific article (publication date: 12 April 2012)

Superior serum half life of albumin tagged TNF ligands

scientific article

Systemic versus local therapy with recombinant tumor necrosis factor-alpha (r-TNF-alpha) in patients with advanced tumors

scientific article

T cell-mediated cytotoxic immune response to HSV infection and its modification due to antimetabolites

scientific article published on January 1, 1979

T-T cell interactions during cytotoxic T cell responses. IV. Murine lymphoid dendritic cells are powerful stimulators for helper T lymphocytes

scientific article published on 01 April 1982

T-T cell interactions during cytotoxic T lymphocyte (CTL) responses: T cell derived helper factor (Interleukin 2) as a probe to analyze CTL responsiveness and thymic maturation of CTL progenitors

scientific article published on January 1980

T-T cell interactions during in vitro cytotoxic T cell responses. VI. The role of T cell-derived colony-stimulating factor in helper T cell activation

scientific article published on 01 February 1984

T-T cell interactions during in vitro cytotoxic T lymphocyte (CTL) responses. II. Helper factor from activated Lyt 1+ T cells is rate limiting i) in T cell responses to nonimmunogenic alloantigen, ii) in thymocyte responses to allogeneic stimulator

scientific article published on 01 March 1980

T-T cell interactions during in vitro cytotoxic T lymphocyte responses. III. Antigen-specific T helper cells release nonspecific mediator(s) able to help induction of H-2-restricted cytotoxic T lymphocyte responses across cell-impermeable membranes

scientific article

T-T cell interactions during in vitro cytotoxic T lymphocyte responses. V. Precursor frequencies and specificity of alloreactive helper T cells

scientific article published on July 1, 1982

T-T-cell interactions during in vivo responses to transplantation antigens

scientific article published on March 1, 1977

T-cell-derived helper factor allows Lyt 123 thymocytes to differentiate into cytotoxic T lymphocytes

scientific article published on August 2, 1979

T-cell-mediated cytotoxicity against herpes simplex virus-infected target cells

scientific article published on February 17, 1977

TNF down-regulation of receptor tyrosine kinase-dependent mitogenic signal pathways as an important step in cytostasis induction and commitment to apoptosis of Kym-1 rhabdomyosarcoma cells

scientific article

TNF inhibits insulin induced STAT5 activation in differentiated mouse muscle cells pmi28.

scientific article published on November 1998

TNF receptor 2 protects oligodendrocyte progenitor cells against oxidative stress

scientific article published on 25 September 2013

TNF receptors TR60 and TR80 can mediate apoptosis via induction of distinct signal pathways

scientific article published on September 1994

TNF signal transduction and TNF-responsive genes

scientific article published on January 1, 1992

TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice

scientific article published on 31 March 2020

TNF-Selectokine: a novel prodrug generated for tumor targeting and site-specific activation of tumor necrosis factor

scientific article published on 01 June 2002

TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy

scientific article

TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes

scientific article published on 07 August 2019

TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60

scientific article published on 01 September 1998

TR60 and TR80 tumor necrosis factor (TNF)-receptors can independently mediate cytolysis

scientific article

Tailoring the stealth properties of biocompatible polysaccharide nanocontainers

scientific article published on 16 February 2015

Target-selective activation of a TNF prodrug by urokinase-type plasminogen activator (uPA) mediated proteolytic processing at the cell surface

scientific article published on 25 April 2006

Targeted lipid-coated nanoparticles: delivery of tumor necrosis factor-functionalized particles to tumor cells

scientific article published on 21 March 2009

Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells.

scientific article

Tetravalent antibody-scTRAIL fusion proteins with improved properties

scientific article

The Role of the Major Histocompatibility Gene Complex in Murine Cytotoxic T Cell Responses

scientific article published on January 1, 1980

The cytotoxic activity of mouse T lymphocytes against allogeneic cytotoxic T cells

scientific article published on August 1, 1975

The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability

scientific article published on March 2005

The in Vivo Effects of Interleukin 2 (TCGF)

scientific article published on March 1, 1982

The role of T cells in anti-herpes simplex virus immunity. I. Induction of antigen-specific cytotoxic T lymphocytes

scientific article

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

scientific journal article

Therapeutic targeting of CD95 and the TRAIL death receptors

scientific article published on September 2011

Trimer stabilization, oligomerization, and antibody-mediated cell surface immobilization improve the activity of soluble trimers of CD27L, CD40L, 41BBL, and glucocorticoid-induced TNF receptor ligand

scientific article

Tumor necrosis factor (TNF) alpha: control of TNF-sensitivity and molecular mechanisms of TNF-mediated growth inhibition

scientific article published on July 1987

Tumor necrosis factor (TNF)-functionalized nanostructured particles for the stimulation of membrane TNF-specific cell responses

scientific article published on November 2005

Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pat

scientific journal article

Tumor necrosis factor and lymphotoxin gene expression in human tumor cell lines.

scientific article published in October 1988

Tumor necrosis factor enhances HLA-A,B,C and HLA-DR gene expression in human tumor cells

scientific article published on 01 February 1987

Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells

scientific article published on 01 November 1998

Tumor necrosis factor inhibits MYC expression in HL-60 cells at the level of mRNA transcription

scientific article

Tumor necrosis factor signal transduction. Cell-type-specific activation and translocation of protein kinase C.

scientific article published on April 1990

Tumor necrosis factor signal transduction. Tissue-specific serine phosphorylation of a 26-kDa cytosolic protein.

scientific article

Tumor necrosis factor signaling.

scientific article

Tumor necrosis factor-induced changes of gene expression in U937 cells. Differentiation-dependent plasticity of the responsive state

scientific article published on 01 May 1988

Tumor necrosis factors in 1996.

scientific article

Tumor therapeutics by design: targeting and activation of death receptors

scientific article

Tumour necrosis factor signal transduction

scientific article published on January 1990

Virion Antigens Introduced Exogeneously into the Cell Membrane Render Syngeneic Target Cells Susceptible for T Cell-Mediated Cytolysis

scientific article published on September 1, 1977

Virus and trinitrophenol hapten-specific T-cell-mediated cytotoxicity against H-2 incompatible target cells

scientific article published on April 1, 1976

[From tumor necrosis factor to TRAIL-AMAIZe: second generation antitumorally effective cytokines]

scientific article published on 01 February 2001

[Molecular biology in tumor diagnosis. New ways for the detection, classification and staging of malignant lymphomas]

scientific article published on 01 February 1986