List of works - Gerard D Schellenberg

A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains

scientific article published on 18 January 2017

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

scientific article published on 19 June 2017

A framework for the interpretation of de novo mutation in human disease

scientific article (publication date: 3 August 2014)

A genome-wide scan for common alleles affecting risk for autism

scientific journal article

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder

scientific article published on 14 October 2011

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

scientific article

ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.

scientific article

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

scientific article

Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain

scientific article published on 01 December 2019

Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls

scientific article

Assessment of the genetic variance of late-onset Alzheimer's disease

scientific article published on 03 March 2016

Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals

scientific article

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

scientific article

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

scientific article

Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants

scientific article published on 6 October 2017

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

scientific article

Common polygenic variation enhances risk prediction for Alzheimer's disease

scientific article published on 21 October 2015

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Comprehensive search for Alzheimer disease susceptibility loci in the APOE region

scientific article published on October 2012

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders

scientific article

Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

scientific article published on 8 July 2013

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam.

scientific article

Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium

scientific article

Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability

scientific article

Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport

scientific article

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records

scientific article

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

scientific article

Functional impact of global rare copy number variation in autism spectrum disorders

scientific article published on 15 July 2010

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

scientific article

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease

scientific article published on 08 July 2019

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project

scientific article published on 27 February 2018

Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration

scientific article

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

scientific article

Genetic association of progressive supranuclear palsy (PSP) risk loci variants with brain gene expression and neuropathology endophenotypes

article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

scientific article published on 01 August 2020

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

scientific article

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

scientific article published on 28 February 2017

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

scientific article published on 16 June 2015

Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

scientific article

Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease

scientific article published on 20 February 2018

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

scientific article

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

scientific article

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

scientific article

Individual common variants exert weak effects on the risk for autism spectrum disorders

scientific journal article

Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci

scientific article published on 30 January 2013

Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

scientific article

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

article

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes

scientific article

Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Missense variant in TREML2 protects against Alzheimer's disease

scientific article published on 21 December 2013

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis ⬇️

scientific article published on 19 October 2020

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

One for all and all for One: Improving replication of genetic studies through network diffusion

scientific article published on 23 April 2018

PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation

scientific article published on 29 July 2014

Patterns and rates of exonic de novo mutations in autism spectrum disorders

scientific article

Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative

scientific article published in October 2007

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

scientific article

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders

scientific article published on January 2013

Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Replication of progressive supranuclear palsy genome-wide association study identifies SLCO1A2 and DUSP10 as new susceptibility loci

scholarly article by Monica Y Sanchez-Contreras published in July 2018

Research goals in progressive supranuclear palsy

SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians

scientific article

Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease

scientific article published on 14 January 2016

Sex differences in the genetic predictors of Alzheimer's pathology

scientific article published on 01 September 2019

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

scientific article published on 01 August 2018

Sex-specific genetic predictors of Alzheimer's disease biomarkers

scientific article published on 02 July 2018

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

scientific article published on 6 February 2017

Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans

scientific article published on 19 October 2016

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans

scientific article

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.

scientific article published on 13 March 2018

List of works by Gerard D Schellenberg

A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

A framework for the interpretation of de novo mutation in human disease

A genome-wide scan for common alleles affecting risk for autism

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain

Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls

Assessment of the genetic variance of late-onset Alzheimer's disease

Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

Common polygenic variation enhances risk prediction for Alzheimer's disease

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

Comprehensive search for Alzheimer disease susceptibility loci in the APOE region

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders

Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

Cycad exposure and risk of dementia, MCI, and PDC in the Chamorro population of Guam.

Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium

Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability

Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

Functional impact of global rare copy number variation in autism spectrum disorders

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project

Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

Genetic association of progressive supranuclear palsy (PSP) risk loci variants with brain gene expression and neuropathology endophenotypes

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

Individual common variants exert weak effects on the risk for autism spectrum disorders

Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci

Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes

Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Missense variant in TREML2 protects against Alzheimer's disease

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis ⬇️

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

One for all and all for One: Improving replication of genetic studies through network diffusion

PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation

Patterns and rates of exonic de novo mutations in autism spectrum disorders

Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders

Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

Replication of progressive supranuclear palsy genome-wide association study identifies SLCO1A2 and DUSP10 as new susceptibility loci

Research goals in progressive supranuclear palsy

SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians

Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease

Sex differences in the genetic predictors of Alzheimer's pathology

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

Sex-specific genetic predictors of Alzheimer's disease biomarkers