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List of works by Francois X Claret

A four-methylated mRNA signature-based risk score system predicts survival in patients with hepatocellular carcinoma

A new group of conserved coactivators that increase the specificity of AP-1 transcription factors

scientific article

A shift in the ligand responsiveness of thyroid hormone receptor alpha induced by heterodimerization with retinoid X receptor alpha

scientific article published on January 1996

AP-1 Transcription Factors as Regulators of Immune Responses in Cancer

scientific article published on 23 July 2019

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

scientific article

Activation of the JNK/SAPK and P38 Mitogen-Activated Protein Kinase Signaling Pathways Sensitize Tumor Cells to Cisplatin-Induced Apoptosis

scientific article published on 12 December 2001

Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21) ⬇️

scientific article published on March 11, 2011

All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity

scientific article

Autophagy in the "inflammation-carcinogenesis" pathway of liver and HCC immunotherapy

scientific article published on 5 October 2017

Clinical implications of hepatitis B viral infection in Epstein-Barr virus-associated nasopharyngeal carcinoma

scientific article published on 27 November 2014

Constitutive control of AKT1 gene expression by JUNB/CJUN in ALK+ anaplastic large-cell lymphoma: a novel crosstalk mechanism.

scientific article

Correction: Stat3 inhibitor stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma

scientific article published on 13 August 2020

Curcumin analogue T83 exhibits potent antitumor activity and induces radiosensitivity through inactivation of Jab1 in nasopharyngeal carcinoma

scientific article

Dickkopf-1 is a key regulator of myeloma bone disease: opportunities and challenges for therapeutic intervention

scientific article

Down-regulation of the cyclin-dependent kinase inhibitor p57 is mediated by Jab1/Csn5 in hepatocarcinogenesis

scientific article published on 25 November 2015

Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer.

scientific article published on 04 February 2014

Essential roles of Jab1 in cell survival, spontaneous DNA damage and DNA repair ⬇️

scientific article published on August 30, 2010

Evidence of a retinoid signaling alteration involving the activator protein 1 complex in tumorigenic human bronchial epithelial cells and non-small cell lung cancer cells.

scientific article published on March 1997

Hsa-miR-24-3p increases nasopharyngeal carcinoma radiosensitivity by targeting both the 3'UTR and 5'UTR of Jab1/CSN5.

scientific article published on 09 May 2016

Hydroxychloroquine synergizes with the PI3K inhibitor BKM120 to exhibit antitumor efficacy independent of autophagy

scientific article published on 29 November 2021

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

scientific article

Immuno-electron microscopic identification of human estrogen receptor-DNA complexes at the estrogen-responsive element and in the first intron of a Xenopus vitellogenin gene

scientific article published on 01 November 1988

Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.

scientific article

Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

scientific article published on December 1995

Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1

scientific article

Involvement of microRNA-24 and DNA methylation in resistance of nasopharyngeal carcinoma to ionizing radiation

scientific article

JAB1/CSN5: a new player in cell cycle control and cancer

scientific article

Jab1/COPS5 as a Novel Biomarker for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Human Cancer

scientific article published on 27 February 2018

Jab1/CSN5 negatively regulates p27 and plays a role in the pathogenesis of nasopharyngeal carcinoma.

scientific article

Jab1/Cops5 contributes to chemoresistance in breast cancer by regulating Rad51

scientific article published on 20 September 2018

Jab1/Csn5-Thioredoxin Signaling in Relapsed Acute Monocytic Leukemia under Oxidative Stress

scientific article

Lasting N-Terminal Phosphorylation of c-Jun and Activation of c-Jun N-Terminal Kinases after Neuronal Injury ⬇️

scientific article published on July 15, 1998

Lysophosphatidic acid induction of urokinase plasminogen activator secretion requires activation of the p38MAPK pathway.

scientific article

Macrophage migration inhibitory factor expression is increased in pituitary adenoma cell nuclei.

scientific article published in January 2003

Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells

scientific article published on 11 December 2003

MicroRNA-17 acts as a tumor chemosensitizer by targeting JAB1/CSN5 in triple-negative breast cancer

scientific article published on 29 August 2019

Molecular markers to assess short-term disease local recurrence in nasopharyngeal carcinoma

scientific article

Mutual regulation of microRNAs and DNA methylation in human cancers

scientific article published on 6 January 2017

NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma.

scientific article published on 6 April 2007

Novel biomarkers of nasopharyngeal carcinoma metastasis risk identified by reverse phase protein array based tumor profiling with consideration of plasma Epstein-Barr virus DNA load.

scientific article published on 24 November 2016

Novel roles of reactive oxygen species in the pathogenesis of acute myeloid leukemia

scientific article

Personalized drug combinations to overcome trastuzumab resistance in HER2-positive breast cancer

scientific article

Phosphatases: the new brakes for cancer development?

scientific article published on 31 October 2011

Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma

scientific article published on September 2006

Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells ⬇️

scientific article published on June 20, 2011

Stat3 contributes to cancer progression by regulating Jab1/Csn5 expression

scientific article published on 15 August 2016

Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma

scientific article

Suppression of Jab1/CSN5 induces radio- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways

scientific article published on 16 July 2012

Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells

scientific article published on 12 March 2003

Targeting Jab1/CSN5 in nasopharyngeal carcinoma

scientific article

The novel Jab1 inhibitor CSN5i-3 suppresses cell proliferation and induces apoptosis in human breast cancer cells

scientific article published on 07 March 2019

The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma.

scientific article published on 22 August 2014

Trastuzumab: Updated Mechanisms of Action and Resistance in Breast Cancer ⬇️

scientific article published on June 18, 2012

Tumor-infiltrating immune cells in hepatocellular carcinoma: Tregs is correlated with poor overall survival

scientific article published on 02 April 2020

Verteporfin inhibits PD-L1 through autophagy and the STAT1-IRF1-TRIM28 signaling axis, exerting antitumor efficacy

scientific article published on 07 April 2020

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

scientific journal article

YAP1 Promotes Tumor Invasion and Metastasis in Nasopharyngeal Carcinoma with Hepatitis B Virus Infection

scientific article published on 17 June 2020

hsa‑miR‑24 suppresses metastasis in nasopharyngeal carcinoma by regulating the c‑Myc/epithelial‑mesenchymal transition axis

article published in 2018

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