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List of works by John R Ussher

5'-AMP-activated protein kinase increases glucose uptake independent of GLUT4 translocation in cardiac myocytes

scientific article

Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat.

scientific article published on 14 May 2015

Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation ⬇️

scientific article published on August 20, 2010

Cardiac insulin resistance: it's sweeter than you think

scientific article published in August 2013

Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy

scientific article published on 16 July 2013

Cardiomyocyte glucagon receptor signaling modulates outcomes in mice with experimental myocardial infarction

scientific article published on 29 November 2014

Cardiovascular actions of incretin-based therapies

scientific article published on May 2014

Cardiovascular biology of the incretin system

scientific article

Cellular Sites and Mechanisms Linking Reduction of Dipeptidyl Peptidase-4 Activity to Control of Incretin Hormone Action and Glucose Homeostasis

scientific article published on 4 November 2016

Decreased Maternal Cardiac Glucose Oxidation: Taking One for the Fetus

scientific article published in December 2017

Female offspring born to obese and insulin-resistant dams are not at increased risk for obesity and metabolic dysfunction during early development

scientific article published on 8 September 2017

FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression

scientific article published on 7 July 2017

Genetic and Pharmacological Inhibition of Malonyl CoA Decarboxylase Does Not Exacerbate Age-Related Insulin Resistance in Mice.

scientific article

Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice

scientific article published on 31 October 2011

Glucagon-like peptide-1 receptor mediated control of cardiac energy metabolism

scientific article published in February 2018

Glucagon-like peptide-2 promotes gallbladder refilling via a TGR5-independent, GLP-2R-dependent pathway

scientific article published on 31 March 2017

Gut microbiota metabolism of L-carnitine and cardiovascular risk.

scientific article

Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction

scientific article published on 20 December 2017

Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection

scientific article published on 9 May 2014

Inhibition of Dipeptidyl Peptidase-4 Impairs Ventricular Function and Promotes Cardiac Fibrosis in High Fat-Fed Diabetic Mice

scientific article published on 15 December 2015

Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice.

scientific article published on 8 November 2012

Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption

scientific article published on 3 June 2010

Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance.

scientific article published on 22 May 2012

Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase

scientific article published on 28 May 2009

Lipotoxicity in obesity and diabetes-related cardiac dysfunction

scientific article published on 17 February 2016

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

scientific article published on January 2008

Myocardial fatty acid metabolism in health and disease

scientific article published on January 2010

Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation

scientific article published on 06 April 2020

Pyridine Nucleotide Regulation of Cardiac Intermediary Metabolism ⬇️

scientific article published on August 17, 2012

Revisiting protein acetylation and myocardial fatty acid oxidation

scientific article published on 23 June 2017

Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle.

scientific article published in August 2009

SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model

scientific article published on 30 October 2021

Something Old Holds Potential to Be Something New in Heart Failure: Allopurinol Revisited ⬇️

scientific article published on July 25, 2012

Sugar-sweetened beverages and vascular function: food for thought.

scientific article

Sweet as sugar: excessive glucose metabolism in the failing heart

scientific article published on July 2014

TCF1 links GIPR signaling to the control of beta cell function and survival

scientific article published on 7 December 2015

Targeting ceramide metabolism in obesity

scientific article

Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart.

scientific article published on 20 January 2011

Targeting intermediary metabolism in the hypothalamus as a mechanism to regulate appetite

scientific article published on 14 April 2010

Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion

scientific article published on 26 February 2009

The Emerging Role of Metabolomics in the Diagnosis and Prognosis of Cardiovascular Disease

scientific article published on December 2016

The autonomic nervous system and cardiac GLP-1 receptors control heart rate in mice

scientific article published in September 2017

The impact of current and novel anti-diabetic therapies on cardiovascular risk

scientific article

The malonyl CoA axis as a potential target for treating ischaemic heart disease

scientific article published on 22 May 2008

The role of cardiac lipotoxicity in the pathogenesis of diabetic cardiomyopathy

scientific article published on 19 February 2014

Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice

scientific article

Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function

scientific article published on 2 October 2009

l-Citrulline supplementation improves glucose and exercise tolerance in obese male mice

scientific article published on 15 January 2020

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