List of works by Laura P James

A Cytochrome P450-Independent Mechanism of Acetaminophen-Induced Injury in Cultured Mouse Hepatocytes

scientific article published on 11 June 2015

A Multicenter, Randomized, Open-Label, Pharmacokinetics and Safety Study of Pantoprazole Tablets in Children and Adolescents Aged 6 Through 16 Years With Gastroesophageal Reflux Disease ⬇️

scientific article published on September 17, 2010

A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents

scientific article published on 01 October 2018

A Weight Estimation Strategy for Preterm and Full-Term Infants

scientific article published on 21 December 2017

Accuracy of the Spacelabs 90217 ambulatory blood pressure monitor in a pediatric population

scientific article

Acetaminophen Protein Adducts in Hospitalized Children Receiving Multiple Doses of Acetaminophen

scientific article published on 17 May 2019

Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia

scientific article

Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways

scientific article published on 30 January 2019

Acetaminophen protein adduct formation following low-dose acetaminophen exposure: comparison of immediate-release vs extended-release formulations.

scientific article published on 28 September 2012

Acetaminophen toxicity in mice lacking NADPH oxidase activity: role of peroxynitrite formation and mitochondrial oxidant stress

scientific article published in December 2003

Acetaminophen-associated hepatic injury: evaluation of acetaminophen protein adducts in children and adolescents with acetaminophen overdose

scientific article

Acetaminophen-induced hepatotoxicity

scientific article (publication date: December 2003)

Acetaminophen-induced hepatotoxicity and protein nitration in neuronal nitric-oxide synthase knockout mice

scientific article published on 14 October 2011

Acetaminophen-induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase

scientific article

Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition

scientific article

Acute Liver Failure of Indeterminate Etiology: A Comprehensive Systematic Approach by An Expert Committee to Establish Causality

scientific article published on 27 June 2018

Acute mental status changes and hyperchloremic metabolic acidosis with long-term topiramate therapy

scientific article published on 01 January 2000

Acylcarnitine profiles in acetaminophen toxicity in the mouse: comparison to toxicity, metabolism and hepatocyte regeneration

scientific article published on 02 August 2013

Advances in biomarker development in acetaminophen toxicity

scientific article published on 27 April 2020

An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients With Acute Liver Injury or Failure

scientific article published on 15 September 2016

An anthropometric survey of US pre-term and full-term neonates

scientific article

Caffeine decreases intermittent hypoxia in preterm infants nearing term-equivalent age.

scientific article

Characterization of delayed liquid gastric emptying in children by the (13)C-acetate breath test

scientific article published on 27 November 2009

Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates

scientific article published on 21 December 2017

Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity

scientific article

Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures.

scientific article

Correlation of MCP1 with toxicity in acetaminophen overdose

scientific article

Correlation of MRI findings to histology of acetaminophen toxicity in the mouse.

scientific article published on 3 November 2011

Cyclic Antidepressant Toxicity in Children and Adolescents ⬇️

scientific article published on 01 April 1995

Cytokines and toxicity in acetaminophen overdose

scientific article

Dalbavancin Pharmacokinetics and Safety in Children 3 Months to 11 Years of Age.

scientific article published on 3 January 2017

Detection of Acetaminophen Protein Adducts in Children With Acute Liver Failure of Indeterminate Cause

scientific article published on 01 September 2006

Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection

scientific article published in April 2002

Echinomycin decreases induction of vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity in mice

scientific article published on 9 November 2011

Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation

scientific article published on 25 July 2003

Effect of placebo on ambulatory blood pressure monitoring in children

scientific article

Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice

scientific article

Elevation of serum interleukin 8 levels in acetaminophen overdose in children and adolescents

scientific article

Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepatocytes

scientific article published on 9 September 2014

Evaluation of occult acetaminophen hepatotoxicity in hospitalized children receiving acetaminophen. Pediatric Pharmacology Research Unit Network

scientific article

External Evaluation of Risperidone Population Pharmacokinetic Models Using Opportunistic Pediatric Data

scientific article published on 17 March 2022

Famotidine disposition in children and adolescents with chronic renal insufficiency

scientific article

Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children

scientific article published on 01 January 2020

Human recombinant vascular endothelial growth factor reduces necrosis and enhances hepatocyte regeneration in a mouse model of acetaminophen toxicity

scientific article

Indocyanine green clearance varies as a function of N-acetylcysteine treatment in a murine model of acetaminophen toxicity

scientific article

Induction of the nuclear factor HIF-1alpha in acetaminophen toxicity: evidence for oxidative stress

scientific article published on 3 March 2006

Interleukin 6 and hepatocyte regeneration in acetaminophen toxicity in the mouse

scientific article published in October 2003

Isoniazid hepatotoxicity: progress in understanding the immunologic component ⬇️

scientific article published on 27 January 2014

Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration

scientific article published on 11 March 2018

Measurement of acetaminophen-protein adducts in children and adolescents with acetaminophen overdoses. .

scientific article

Measurement of serum acetaminophen-protein adducts in patients with acute liver failure

scientific article

Mechanisms of chloroform-induced hepatotoxicity: oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes.

scientific article published in November 2007

Metabolomics Analysis of Urine Samples from Children after Acetaminophen Overdose

scientific article published on 6 September 2017

MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity

scientific article published on 26 September 2017

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

scientific article

Nitrosative stress and lipid homeostasis as a mechanism for zileuton hepatotoxicity and resistance in genetically sensitive mice

scientific article published on 14 March 2020

Obese Children Require Lower Doses of Pantoprazole Than Nonobese Peers to Achieve Equal Systemic Drug Exposures

scientific article published in February 2018

Obesity-related asthma in children: A role for vitamin D

scientific article published on 15 September 2020

Omeprazole disposition in children following single-dose administration

scientific article published in August 2003

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life

scientific article

Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration

scientific article published on 17 June 2019

Pharmacokinetics and pharmacodynamics of famotidine in children

scientific article published on 01 January 1996

Pharmacokinetics and pharmacodynamics of famotidine in infants

scientific article published on 01 December 1998

Pharmacokinetics and pharmacodynamics of famotidine in paediatric patients

scientific article published on August 1996

Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure

scientific article published on 13 May 2009

Pharmacokinetics of famotidine in infants

scientific article published in January 2005

Pharmacokinetics, Safety, and Tolerability of Single-Dose Intravenous Moxifloxacin in Pediatric Patients: Dose Optimization in a Phase 1 Study

scientific article published on 25 January 2019

Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children

scientific article published on 04 December 2019

Population Pharmacokinetics and Safety of Solithromycin following Intravenous and Oral Administration in Infants, Children, and Adolescents

scientific article published on 27 July 2018

Population pharmacokinetics of metronidazole evaluated using scavenged samples from preterm infants

scientific article published on 17 January 2012

Population pharmacokinetics of piperacillin using scavenged samples from preterm infants

scientific article

Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children

scientific article

Pre-treatment twice with liposomal clodronate protects against acetaminophen hepatotoxicity through a pre-conditioning effect

scientific article published on 29 July 2020

Protein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity.

scientific article published on 9 May 2013

SIRT1 Controls Acetaminophen Hepatotoxicity by Modulating Inflammation and Oxidative Stress

scientific article published on 31 October 2017

Salivary caffeine concentrations are comparable to plasma concentrations in preterm infants receiving extended caffeine therapy

scientific article

Single dose pharmacokinetics of linezolid in infants and children.

scientific article published in December 2000

Single dose pharmacokinetics of pleconaril in neonates. Pediatric Pharmacology Research Unit Network

scientific article published on September 2000

Single-dose pharmacokinetics of a pleconaril (VP63843) oral solution in children and adolescents. Pediatric Pharmacology Research Unit Network

scientific article

Single-dose pharmacokinetics of oral and intravenous pantoprazole in children and adolescents

scientific article

Solithromycin Pharmacokinetics in Plasma and Dried Blood Spots and Safety in Adolescents

scientific article published on 16 February 2016

Susceptibility to acetaminophen (APAP) toxicity unexpectedly is decreased during acute viral hepatitis in mice

scientific article

Targeted liquid chromatography-mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children

scientific article

Targeted metabolomic profiling indicates structure-based perturbations in serum phospholipids in children with acetaminophen overdose

scientific article published on 23 August 2016

Temporal Variations in Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 Infections by Race and Ethnicity in Arkansas

scientific article published on 23 March 2022

The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling

scientific article published on 14 January 2019

The neuronal nitric oxide synthase inhibitor NANT blocks acetaminophen toxicity and protein nitration in freshly isolated hepatocytes.

scientific article published on 07 October 2015

The pharmacokinetics of continuous infusion pralidoxime in children with organophosphate poisoning.

scientific article

The pharmacokinetics of oral ranitidine in children and adolescents with cystic fibrosis

scientific article published on 01 December 1999

The proper use of acetaminophen

scientific article published on November 2011

The use of glucagon in nifedipine poisoning complicated by clonidine ingestion

scientific article published on 01 December 1997

Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes.

scientific article published on January 2017

Tumour necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: a kinetic study of proliferating cell nuclear antigen and cytokine expression

scientific article published in July 2005

Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure

scientific article published on 10 January 2011

Use of normalized prediction distribution errors for assessing population physiologically-based pharmacokinetic model adequacy

scientific article published on 22 April 2020

Vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity

scientific article published on 24 March 2006

miRNA-122 Protects Mice and Human Hepatocytes from Acetaminophen Toxicity by Regulating Cytochrome P450 Family 2 Subfamily A Member 2 and E Member 1 Expression

scientific article

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