List of works by William J Burlingham

A Human Pluripotent Stem Cell-Based Screen for Smooth Muscle Cell Differentiation and Maturation Identifies Inhibitors of Intimal Hyperplasia.

scientific article

A Humanized Mouse Model Generated Using Surplus Neonatal Tissue.

scientific article published on 17 March 2018

A comparison of donor-specific and random transfusions in living-related renal transplantation and their effect on steroid withdrawal

scientific article published on 01 February 1991

A lesson in tolerance--maternal instruction to fetal cells

scientific article

A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas ⬇️

scientific article published on October 27, 2010

A rapid assay for measuring both colony size and cytolytic activity of limiting dilution microcultures

scientific article published in February 1988

Activation of HLA-A2-specific memory B cells in severe combined immunodeficient mice.

scientific article published in May 1993

Adsorption of cytotoxic anti-HLA antibodies with HLA class I immunosorbant beads

scientific article published on May 1990

Altered distribution of H60 minor H antigen-specific CD8 T cells and attenuated chronic vasculopathy in minor histocompatibility antigen mismatched heart transplantation in Cxcr3-/- mouse recipients.

scientific article published in December 2007

An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model

scientific article

An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells

scientific article

Analysis of indirect pathway CD4+ T cells in a patient with metastable tolerance to a kidney allograft: possible relevance to superior graft survival of HLA class II closely matched renal allografts

scientific article published on 21 January 2009

Analysis of the CD1 antigen presenting system in humanized SCID mice

scientific article (publication date: 2011)

Anti-idiotypes and transfusions.

scientific article published on December 1988

Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction

scientific article

Autoimmune Reactivity in Graft Injury: Player or Bystander?

scientific article published on 7 July 2015

Bidirectional alloreactivity: A proposed microchimerism-based solution to the NIMA paradox

scientific article

Bioengineered vocal fold mucosa for voice restoration

scientific article

CMV-infected allogeneic endothelial cells initiate responder and bystander donor HLA class I release via the metalloproteinase cleavage pathway

scientific article published on 01 March 2005

Cell-mediated immunity to collagen V in lung transplant recipients: correlation with collagen V release into BAL fluid

scientific article published on 01 February 2001

Changes in donor-specific cell-mediated lympholysis (CML) response associated with success of early steroid withdrawal in DST-azathioprine-treated renal transplant recipients

scientific article published on 01 February 1989

Chimerism, tolerance, and twins

scientific article published on 01 August 2010

Chronic human skin graft rejection in severe combined immunodeficient mice engrafted with human PBL from an HLA-presensitized donor

scientific article published on March 1, 1992

Clonotype analysis of human alloreactive T cells: a novel approach to studying peripheral tolerance in a transplant recipient

scientific article

Correlation between post transplant maternal microchimerism and tolerance across MHC barriers in mice

scientific article published on July 2011

Dendritic cell type determines the mechanism of bystander suppression by adaptive T regulatory cells specific for the minor antigen HA-1.

scientific article

Detection of microchimerism by minor histocompatibility antigen HA-1 allele-specific nested polymerase chain reaction

scientific article published on 01 May 2005

Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance.

scientific article published in November 2007

Differential requirement for P2X7R function in IL-17 dependent vs. IL-17 independent cellular immune responses

scientific article published on 27 May 2014

Donor HLA-DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation

scientific article published on 24 September 2020

Donor dendritic cell persistence in organ allograft recipients in the absence of immunosuppression

scientific article published on 01 August 1999

Donor-derived exosomes: the trick behind the semidirect pathway of allorecognition

scientific article published on 24 November 2016

Donor-derived human leukocyte antigen class I proteins in the serum of heart transplant recipients

scientific article published on 01 October 1996

Donor-derived small cell lung carcinoma in a kidney transplant recipient

scientific article published in November 2001

Donor-specific cytotoxic T lymphocyte hyporesponsiveness following renal transplantation in patients pretreated with donor-specific transfusions

scientific article published in February 1991

Donor-specific indirect pathway analysis reveals a B-cell-independent signature which reflects outcomes in kidney transplant recipients

scientific article

Donor-specific transfusions in unrelated and related HLA-mismatched donor-recipient combinations

scientific article published on 01 December 1984

Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring.

scientific article

Effect of HLA-DR mismatch on lung transplant outcome

scientific article published on 01 February 2001

Elevated protein kinase C-δ contributes to aneurysm pathogenesis through stimulation of apoptosis and inflammatory signaling

scientific article

Epigenetic Priming of Human Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation

scientific article published on 14 May 2019

Epitope analysis of the collagen type V-specific T cell response in lung transplantation reveals an HLA-DRB1*15 bias in both recipient and donor

scientific article

Epitope fine specificity of human anti-HLA-A2 antibodies

scientific article published on 01 February 1993

Epitope fine specificity of human anti-HLA-A2 antibodies. Identification of four epitopes including a haptenlike epitope on HLA-A2 at lysine 127.

scientific article published on July 1993

Evidence for a possible Th2 bias in human renal transplant tolerance.

scientific article published in February 1995

Evidence that donor spleen cells administered through the portal vein prolong the survival of cardiac allografts in rats

scientific article published on 01 June 1988

Exosomes: The missing link between microchimerism and acquired tolerance?

scientific article published on 17 December 2015

Expression of human recombinant beta 2-microglobulin by Aspergillus nidulans and its activity

scientific article published in December 1996

Extended lung preservation with UW solution does not adversely affect graft outcome

scientific article published on 01 February 2001

Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas.

scientific article published on 11 July 2018

Fetal microchimerism persists at high levels in c-kit stem cells in sensitized mothers

scientific article

Functional characterization of human pluripotent stem cell-derived arterial endothelial cells

scientific article

HLA (A*0201) mimicry by anti-idiotypic monoclonal antibodies

scientific article published on December 1998

HLA class I noninherited maternal antigens in cord blood and breast milk

scientific article published in March 2004

HLA-A, -B, and -DR zero-mismatched kidneys shipped to the University of Wisconsin, Madison, 1993-2006: superior graft survival despite longer preservation time

scientific article

HLA-A2-specific antibody production in severe combined immunodeficient mice reconstituted with human peripheral blood leukocytes from HLA-presensitized donors

scientific article published on 01 February 1993

HY immune tolerance is common in women without male offspring

scientific article

Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance

scientific article published on 01 March 2007

Human CD8+ T-regulatory cells with low-avidity T-cell receptor specific for minor histocompatibility antigens

scientific article published on 21 September 2008

Human NKT cells promote monocyte differentiation into suppressive myeloid antigen-presenting cells

scientific article published on October 2009

Human allograft acceptance is associated with immune regulation

scientific article

Human fetal pancreas--a potential source for transplantation

scientific article published on 01 January 1987

Human interleukin-2 and lymphoproliferative (T-helper cell) responses to soluble HLA class I antigens in vitro: I. Specificity for polymorphic domains

scientific article published on 01 July 1993

Human liver allograft acceptance and the "tolerance assay". II. Donor HLA-A, -B but not DR antigens are able to trigger regulation of DTH.

scientific article published in October 2002

Human liver allograft acceptance and the "tolerance assay": in vitro anti-donor T cell assays show hyporeactivity to donor cells, but unlike DTH, fail to detect linked suppression

scientific article published on 01 August 2001

Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade

scientific article

IL-17 induces type V collagen overexpression and EMT via TGF-β-dependent pathways in obliterative bronchiolitis

scientific article published on 21 December 2012

IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants

scientific article

Identification of PD1-mediated regulation of antitumor antigen response in patients with NSCLC using the trans vivo DTH assay

scientific article published on 01 June 2020

Identification of a B cell signature associated with renal transplant tolerance in humans.

scientific article

Immune regulation and graft survival in kidney transplant recipients are both enhanced by human leukocyte antigen matching

scientific article published on 01 April 2004

Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle

scientific article published on 01 January 1994

Immunobiology of exposure to non-inherited maternal antigens

scientific article published on May 2007

Immunochemical analysis of a recombinant, genetically engineered, secreted HLA-A2/Q10b fusion protein

scientific article published on October 1991

Immunoregulation in liver transplant recipients: possible evidence of tolerance by DTH assay

scientific article published on 01 February 2001

Impact of Leukocyte Function-Associated Antigen-1 Blockade on Endogenous Allospecific T Cells to Multiple Minor Histocompatibility Antigen Mismatched Cardiac Allograft

scientific article published on 22 June 2015

Improved renal allograft survival following donor-specific transfusions. I. Induction of antibodies that inhibit primary antidonor MLC response.

scientific article published in January 1985

Improved renal allograft survival following donor-specific transfusions. II. In vitro correlates of early (DST-type) rejection episodes

scientific article published on January 1987

Improved renal allograft survival following donor-specific transfusions. III. Kinetics of mixed lymphocyte culture responses before and after transplantation

scientific article published on 01 January 1988

In vitro parameters of donor-antigen-specific tolerance

scientific article

Induction of antiidiotypic antibodies to donor HLA-A2 following blood transfusions in a highly sensitized HLA-A2+ recipient

scientific article published on 01 June 1988

Infectious Tolerance as Seen With 2020 Vision: The Role of IL-35 and Extracellular Vesicles

scientific article published on 26 August 2020

Inhibition of both MLC and in vitro IgG memory response to tetanus toxoid by RS-61443

scientific article published on February 1, 1991

Inhibition of human B cell responses in vitro by RS-61443, cyclosporine A and DAB486 IL-2

scientific article published on 01 February 1991

Inhibition of human antigen-specific memory B cell response in vitro by a diphtheria toxin-related interleukin 2 fusion protein.

scientific article published in February 1991

Interferon-gamma drives the metalloproteinase-dependent cleavage of HLA class I soluble forms from primary human bronchial epithelial cells.

scientific article published in October 2002

Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance

scientific article published on 18 October 2013

Interleukin-17-dependent autoimmunity to collagen type V in atherosclerosis

scientific article

Kinetics of Alloantigen-Specific Regulatory CD4 T Cell Development and Tissue Distribution After Donor-Specific Transfusion and Costimulatory Blockade

scientific article published on 21 April 2016

Kinetics of antidonor mixed lymphocyte culture responses in donor specific transfusions plus azathioprine-treated patients

scientific article published on 01 February 1987

LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis

scientific article

Lacto-N-fucopentaose III, a Pentasaccharide, Prolongs Heart Transplant Survival ⬇️

scientific article published on November 27, 2010

Leukocyte-Associated Ig-like Receptor 1 Inhibits T1 Responses but Is Required for Natural and Induced Monocyte-Dependent T17 Responses

article

Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients

scientific article

Loss of tolerance to a maternal kidney transplant is selective for HLA class II: evidence from trans-vivo DTH and alloantibody analysis.

scientific article published in December 2000

Loss of tolerance to self after transplant

scientific article published on 06 February 2011

Lung transplant patients' T cell responses to influenza vaccine viruses between seasons

scientific article published on 31 March 2008

Mechanism of action of donor-specific transfusion: inhibition of mixed lymphocyte culture response by patient plasma

scientific article published on 01 December 1984

Meeting report of the First Symposium on Chimerism

scientific article published on October 2013

Metastable tolerance in nonhuman primates and humans.

scientific article published on March 2004

Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates

scientific article published in May 2004

Mice engrafted with human fetal thymic tissue and hematopoietic stem cells develop pathology resembling chronic graft-versus-host disease.

scientific article published on 24 June 2013

Microchimerism and regulation in living related kidney transplant families

scientific article published on 17 December 2015

Microchimerism in cord blood: mother as anticancer drug

scientific article published on 7 February 2012

Microchimerism is strongly correlated with tolerance to noninherited maternal antigens in mice

scientific article published on 21 August 2009

Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient

scientific article published on 01 April 1995

Microchimerism: tolerance vs. sensitization

scientific article published in August 2011

Milk and the "Grandmother Effect"- a new contribution to the legacy of Ray Owen

article

Minor H antigen HA-1-specific regulator and effector CD8+ T cells, and HA-1 microchimerism, in allograft tolerance

scientific article

Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance

scientific article published on 17 January 2017

Monitoring of kidney and simultaneous pancreas-kidney transplantation rejection by release of donor-specific, soluble HLA class I

scientific article published on 01 July 1994

Monitoring the patient off immunosuppression. Conceptual framework for a proposed tolerance assay study in liver transplant recipients.

scientific article

Mouse strain and injection site are crucial for detecting linked suppression in transplant recipients by trans-vivo DTH assay.

scientific article published on 6 December 2006

Mucosal Administration of Collagen V Ameliorates the Atherosclerotic Plaque Burden by Inducing Interleukin 35-dependent Tolerance.

scientific article published on 31 December 2015

Multivariate analysis of donor-specific versus random transfusion protocols in haploidentical living-related transplants

scientific article published in February 1991

Multivariate analysis of risk factors for sensitization and early rejection episodes in a donor-specific transfusion plus azathioprine protocol

scientific article published on 01 February 1988

Mycophenolate Monotherapy in HLA-Matched Kidney Transplant Recipients: A Case Series of 20 Patients

scientific article published on 17 January 2020

NFATc3 Regulation of Collagen V Expression Contributes to Cellular Immunity to Collagen Type V and Hypoxic Pulmonary Hypertension

scientific article published on 30 September 2020

Naturally acquired tolerance and sensitization to minor histocompatibility antigens in healthy family members

scientific article

Neutralizing IL-17 prevents obliterative bronchiolitis in murine orthotopic lung transplantation

scientific article

Non-inherited maternal antigens, pregnancy, and allotolerance

scientific article

Operational immune tolerance towards transplanted allogeneic pancreatic islets in mice and a non-human primate

scientific article published on 31 January 2019

Patterns of Immune Regulation in Rhesus Macaque and Human Families

scientific article published on 23 July 2015

Peptide-conformed beta2m-free class I heavy chains are intermediates in generation of soluble HLA by the membrane-bound metalloproteinase

scientific article

Pretransplant immune regulation predicts allograft outcome: bidirectional regulation correlates with excellent renal transplant function in living-related donor-recipient pairs

scientific article

Pretransplant immune-regulation predicts allograft tolerance

scientific article

Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation

scientific article published on 7 September 2011

Priming of cytotoxic T lymphocyte precursors by donor-specific transfusions and modulation post transplant in relation to steroid withdrawal

scientific article published on 01 December 1988

Reflux-induced collagen type v sensitization: potential mediator of bronchiolitis obliterans syndrome

scientific article

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials

scientific article published on 01 May 2020

Risk factors for rejection in a donor-specific transfusion plus azathioprine protocol

scientific article published on 01 December 1988

Risk factors for sensitization by blood transfusions. Comparison of the UW/Madison and UC/San Francisco donor-specific transfusion experience.

scientific article published in January 1989

Role of exosomes in tumour and transplant immune regulation

scientific article published on 31 July 2019

Soluble HLA class I in epithelial lining fluid of lung transplants: associations with graft outcome

scientific article published on 01 February 1997

Soluble donor HLA class I and beta 2m-free heavy chain in serum of lung transplant recipients: steady-state levels and increases in patients with recurrent CMV infection, acute rejection episodes, and poor outcome

scientific article published in December 2000

Specific Donor HLA-DR Types Correlate with Altered Susceptibility to Development of Chronic Lung Allograft Dysfunction

scientific article

Stable lung allograft outcome correlates with the presence of intragraft donor-derived leukocytes

scientific article published on 01 November 1998

Stem cell microchimerism and tolerance to non-inherited maternal antigens

scientific article

Successful reduction of immunosuppression in older renal transplant recipients who exhibit donor-specific regulation

scientific article published on August 2009

T-cell responses to hepatitis B surface antigen in lung transplant recipients.

scientific article published in September 2007

Targeted donor complement blockade after brain death prevents delayed graft function in a nonhuman primate model of kidney transplantation

scientific article published on 10 January 2020

Th-17, monokines, collagen type V, and primary graft dysfunction in lung transplantation.

scientific article

Th1 and Th17 immunocompetence in humanized NOD/SCID/IL2rgammanull mice

scientific article

Th17 Responses to Collagen Type V, kα1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout Life

scientific article published on November 2016

The effect of tolerance to noninherited maternal HLA antigens on the survival of renal transplants from sibling donors

scientific article published on 01 December 1998

The emerging role of TH17 cells in organ transplantation.

scientific article published on March 2014

The end of an era: Wayne Streilein and his impact on transplantation immunology

scientific article published in July 2004

The history of the University of Wisconsin transplant program

scientific article published on 01 January 2007

The influence of RS-61443 on antibody-mediated rejection

scientific article published on 01 March 1992

The metalloproteinase-mediated pathway is essential for generation of soluble HLA class I proteins by activated cells in vitro: proposed mechanism for soluble HLA release in transplant rejection

scientific article published in July 1998

The outstanding questions in transplantation: It's about time….

scientific article published on 31 July 2017

The voices of Chimerism

scientific article published on July 2010

Tolerance after solid organ and hematopoietic cell transplantation

scientific article

Tolerance to Noninherited Maternal MHC Antigens in Mice ⬇️

scientific article published on November 15, 2003

Tolerance to noninherited maternal antigens in mice and humans

scientific article

Trans-vivo delayed type hypersensitivity assay for antigen specific regulation

scientific article published on 2 May 2013

Transfer of tolerance to collagen type V suppresses T-helper-cell-17 lymphocyte-mediated acute lung transplant rejection

scientific article

Transplantation Tolerance Induction: Cell Therapies and Their Mechanisms

scientific article

Transplantation immunology.

scientific article

Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance

scientific article published on 01 January 2020

Tumor necrosis factor-alpha and tumor growth factor-beta1 genotype: partial association with intragraft gene expression in two cases of long-term peripheral tolerance to a kidney transplant

scientific article published on 01 April 2000

Use of donor serum to prevent passive transfer of hyperacute rejection

scientific article published on 01 July 1994

Why is the patient out of breath? Collagen V(α1) and K-α1-tubulin take center stage in lung transplantation.

scientific article published on 12 September 2014

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