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List of works by Simon A Gayther

A Comprehensive Gene-Environment Interaction Analysis in Ovarian Cancer using Genome-wide Significant Common Variants

article

A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival

scientific article

A Perl toolkit for LIMS development

scientific article

A Study of High-Grade Serous Ovarian Cancer Origins Implicates the SOX18 Transcription Factor in Tumor Development

scientific article published on 01 December 2019

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A breast/ovarian cancer patient with germline mutations in both BRCA1 and BRCA2

scientific article published on 01 January 1997

A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases

scientific article published on 25 June 2019

A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer

scientific article

A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A

scientific article

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

scientific article

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

scientific article published on 19 September 2010

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro.

scientific article published in July 2004

A molecular genetic and statistical approach for the diagnosis of dual-site cancers.

scientific article published in October 2004

A multi-center study to evaluate the impact of germline BRCA1 and BRCA2 mutations on ovarian cancer survival.

scientific article

A polymorphic stop codon in BRCA2

scientific article published on 01 November 1996

A polymorphism in the GALNT2 gene and ovarian cancer risk in four population based case-control studies

scientific article

A splicing variant of TERT identified by GWAS interacts with menopausal estrogen therapy in risk of ovarian cancer

scientific article

A suite of Perl modules for handling microarray data.

scientific article

A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants

scientific article published on 01 May 2019

ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium

scientific article

Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours

scientific article

Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study

scientific article published on 10 July 2016

Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study

scientific article published on 20 March 2018

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.

scientific article

An epigenetic signature in peripheral blood predicts active ovarian cancer

scientific article

An integrative approach to assess X-chromosome inactivation using allele-specific expression with applications to epithelial ovarian cancer.

scientific article

Analysis of BRCA1 and BRCA2 mutations in Hungarian families with breast or breast-ovarian cancer

scientific article published in May 1997

Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome

scientific article published on 19 March 2013

Apparent human BRCA1 knockout caused by mispriming during polymerase chain reaction: implications for genetic testing

scientific article published on 01 May 2001

Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium

scientific article published on February 2014

Assessing the genetic architecture of epithelial ovarian cancer histological subtypes

scientific article

Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study

scientific article

Assessment of Multifactor Gene-Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors

scientific article

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

scientific article published on 03 July 2020

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

scientific article published on 21 June 2016

Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk

scientific article

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

scientific article

Association between KRAS rs61764370 and triple-negative breast cancer--a false positive?

scientific article published on 01 August 2011

Association between common germline genetic variation in 94 candidate genes or regions and risks of invasive epithelial ovarian cancer

scientific article

Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies

scientific article published in April 2012

Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study

scientific article published on 20 March 2009

Association between single-nucleotide polymorphisms in hormone metabolism and DNA repair genes and epithelial ovarian cancer: results from two Australian studies and an additional validation set.

scientific article published on December 2007

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

scientific article

Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study

scientific article published on 30 July 2018

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study

scientific article published on 4 September 2016

Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer

scientific article

Author Correction: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

scientific article published in Nature Communications

BRCA1 and BRCA2 mutation prevalence and clinical characteristics of a population-based series of ovarian cancer cases from Denmark.

scientific article published in June 2008

BRCA1 and BRCA2 mutations in a population-based study of male breast cancer

scientific article

BRCA1/2 mutation status influences somatic genetic progression in inherited and sporadic epithelial ovarian cancer cases

scientific article published on 01 January 2003

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article

Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium

scientific article published on 23 July 2013

Breast cancer information on the web ⬇️

scientific article published on 01 November 1995

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

CA125 expression pattern, prognosis and correlation with serum CA125 in ovarian tumor patients. From The Danish "MALOVA" Ovarian Cancer Study

scientific article published on 17 November 2006

CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants

scientific article published on 23 September 2015

Cancer stem cells and epithelial ovarian cancer

scientific article

Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk

scientific article published on 03 March 2009

Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis

scientific article published on 08 September 2009

Cell-type-specific enrichment of risk-associated regulatory elements at ovarian cancer susceptibility loci

scientific article published on 24 March 2015

Characterization of fusion genes in common and rare epithelial ovarian cancer histologic subtypes

scientific article published on April 2017

Chromosomes 6 and 18 induce neoplastic suppression in epithelial ovarian cancer cells.

scientific article

Cigarette smoking and risk of ovarian cancer: a pooled analysis of 21 case-control studies

scientific article published on 02 March 2013

Cigarette smoking is associated with adverse survival among women with ovarian cancer: Results from a pooled analysis of 19 studies

scientific article

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

scientific article published on 22 September 2015

Clinical and pathological associations of PTEN expression in ovarian cancer: a multicentre study from the Ovarian Tumour Tissue Analysis Consortium

scientific article published on 18 June 2020

Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer

scientific article published on 05 March 2013

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

scientific article published on 19 June 2015

Common Genetic Variation and Susceptibility to Ovarian Cancer: Current Insights and Future Directions

scientific article published on 14 June 2017

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

scientific article

Common Variants in RB1 Gene and Risk of Invasive Ovarian Cancer

article

Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer

scientific article

Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk

scientific article published on 27 March 2012

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

scientific article

Common variants at 19p13 are associated with susceptibility to ovarian cancer

scientific article

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 20 February 2012

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

scientific article

Common variants in mismatch repair genes and risk of invasive ovarian cancer

scientific article

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers

scientific article

Consortium analysis of 7 candidate SNPs for ovarian cancer

scientific article published on July 2008

Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk

scientific article

Contribution of BRCA1 mutations to ovarian cancer

scientific article published on 01 April 1997

Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

scientific article published on 10 September 2015

Contribution ofBRCA1andBRCA2mutations to inherited ovarian cancer

scientific article published on 01 December 2007

Cost-effectiveness of Population-Based BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2 Mutation Testing in Unselected General Population Women

scientific article published on 18 January 2018

Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)

scientific article published on 17 June 2020

Distribution of p53 expression in tissue from 774 Danish ovarian tumour patients and its prognostic significance in ovarian carcinomas.

scientific article published in May 2008

Down-regulation of ARID1A is sufficient to initiate neoplastic transformation along with epigenetic reprogramming in non-tumorigenic endometriotic cells

scientific article

ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study

scientific article

Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival

scientific article published on February 2008

Eligibility for magnetic resonance imaging screening in the United Kingdom: effect of strict selection criteria and anonymous DNA testing on breast cancer incidence in the MARIBS Study

scientific article

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

scientific article published on 19 January 2017

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk

scientific article

Erratum: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer

scholarly article published in Nature Genetics

Erratum: Validating genetic risk associations for ovarian cancer through the International Ovarian Cancer Association Consortium

scholarly article published in British Journal of Cancer

Estrogen receptor beta rs1271572 polymorphism and invasive ovarian carcinoma risk: pooled analysis within the Ovarian Cancer Association Consortium

scientific article

Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"

scientific article

Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study

Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women

article

Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study

scientific article

Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk

scientific article published on 4 July 2016

Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types

scientific article

Expression level of Wilms tumor 1 (WT1) protein has limited prognostic value in epithelial ovarian cancer: from the Danish "MALOVA" ovarian cancer study

scientific article published on 31 May 2007

Familial gastric cancer: overview and guidelines for management

scientific article

Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers

article

Frequently occurring germ-line mutations of the BRCA1 gene in ovarian cancer families from Russia

scientific article

Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus.

scientific article

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival

scientific article published on 6 March 2009

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival

article

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Functional polymorphisms in the TERT promoter are associated with risk of serious ovarian and breast cancer

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers

scientific article

GENAVi: a shiny web application for gene expression normalization, analysis and visualization

scientific article published on 16 October 2019

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes

scientific article published on 2 February 2012

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

scientific article published on 17 December 2018

Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction

scientific article published on 17 October 2017

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium

scientific article (publication date: March 1998)

Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours

scientific article published on 01 February 2007

Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article

Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium

scientific article

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk

scientific article

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium

scientific article

Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women

scientific article published on 19 March 2019

Genome-wide association study for ovarian cancer susceptibility using pooled DNA.

scientific article published on 13 July 2012

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.

scientific article published on 5 November 2013

Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

scientific article published on 27 August 2015

Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

scientific article

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

article

Germline whole exome sequencing and large-scale replication identifies FANCM as a likely high grade serous ovarian cancer susceptibility gene

scientific article published on 3 March 2017

Grading of serous ovarian carcinoma: further evidence of a lack of agreement between conventional grading systems.

scientific article published on 13 December 2007

HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer

scientific article published on 09 October 2016

Heterotypic Three-dimensional <em>In Vitro</em> Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression ⬇️

scientific article published on August 28, 2012

Histopathology, FIGO stage, and BRCA mutation status of ovarian cancers from the Gilda Radner Familial Ovarian Cancer Registry

scientific article

History of Comorbidities and Survival of Ovarian Cancer Patients, Results from the Ovarian Cancer Association Consortium

scientific article published on September 2017

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article

Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis

scientific article published on 01 December 2021

Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression.

scientific article

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

scientific article published on January 2013

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

scientific article published on 27 April 2016

Identification of germ-line E-cadherin mutations in gastric cancer families of European origin

scientific article published on 01 September 1998

Identification of novel candidate biomarkers of epithelial ovarian cancer by profiling the secretomes of three-dimensional genetic models of ovarian carcinogenesis

scientific article published on 2 July 2015

Identification of novel epithelial ovarian cancer loci in women of African ancestry

scientific article published on 08 October 2019

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

In vitro three-dimensional modeling of fallopian tube secretory epithelial cells.

scientific article

In vitro three-dimensional modelling of human ovarian surface epithelial cells.

scientific article published on 24 April 2009

Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours

scientific article published on 01 June 1999

Inherited Risk of Ovarian Cancer and the Implications for Screening

scientific article published on May 1, 2012

Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration

scientific article published on July 2016

Inherited variants in regulatory T cell genes and outcome of ovarian cancer

scientific article

Integration of Population-Level Genotype Data with Functional Annotation Reveals Over-Representation of Long Noncoding RNAs at Ovarian Cancer Susceptibility Loci

scientific article

Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer

scientific article

Kernel canonical correlation analysis for assessing gene-gene interactions and application to ovarian cancer

scientific article published on 17 April 2013

LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer

scientific article published on 11 April 2011

Large-scale evaluation of common variation in regulatory T cell-related genes and ovarian cancer outcome

scientific article published on 27 January 2014

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

scientific article published in Nature Communications

Lineage-specific epigenomic and genomic activation of oncogene HNF4A promotes gastrointestinal adenocarcinomas

scientific article published on 24 April 2020

Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma

scientific article published on 13 August 2019

Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival

scientific article published on 05 July 2020

MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium

scientific article published on 2 June 2011

Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers.

scientific article

Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients

scientific article published on 22 August 2008

Modelling genetic and clinical heterogeneity in epithelial ovarian cancers.

scientific article

Molecular Analysis of Mixed Endometrioid and Serous Adenocarcinoma of the Endometrium

scientific article published on July 2015

Molecular profiling of cervical cancer progression

scientific article

Molecular signatures of X chromosome inactivation and associations with clinical outcomes in epithelial ovarian cancer

scientific article published on 01 April 2019

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Multiple loci with different cancer specificities within the 8q24 gene desert

scientific article

Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population.

scientific article

Mutation analysis of the c-mos proto-oncogene and the endothelin-B receptor gene in medullary thyroid carcinoma and phaeochromocytoma

scientific article

Mutation analysis of the c-mos proto-oncogene in human ovarian teratomas ⬇️

scientific article published on May 1, 1998

Mutations truncating the EP300 acetylase in human cancers

NPPB is a novel candidate biomarker expressed by cancer-associated fibroblasts in epithelial ovarian cancer

scientific article

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

scientific article

No Evidence That Genetic Variation in the Myeloid-Derived Suppressor Cell Pathway Influences Ovarian Cancer Survival

scientific article published on 27 September 2016

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer

scientific article published on 24 April 2020

Novel three-dimensional in vitro models of ovarian endometriosis

scientific article

Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium

scientific article published on 22 March 2013

Offspring sex and risk of epithelial ovarian cancer: a multinational pooled analysis of 12 case-control studies

scientific article published on 21 September 2020

Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites

scientific article published on 12 September 2020

Ovarian and breast cancer risks associated with pathogenic variants in RAD51C and RAD51D

scientific article published on 28 February 2020

Ovarian cancer aetiology: facts and fiction

scientific article published on April 2006

Ovarian cancer and genetic susceptibility in relation to the BRCA1 and BRCA2 genes. Occurrence, clinical importance and intervention

scientific article

Ovarian cancer risk associated with inherited inflammation-related variants

scientific article published on 26 January 2012

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

scientific article

Ovarian cancer: a clinical challenge that needs some basic answers

scientific article

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

PAX8 expression in ovarian surface epithelial cells

scientific article published on 15 April 2015

PPM1D Mosaic Truncating Variants in Ovarian Cancer Cases May Be Treatment-Related Somatic Mutations

scientific article published on 27 January 2016

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011

Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium

scientific article

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women

scientific article

Polymorphisms in DNA repair genes and epithelial ovarian cancer risk

article

Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium

scientific article published on 27 May 2011

Population-based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high-grade serous ovarian cancer

scientific article published on 16 June 2020

Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer.

scientific article published in September 2008

Principles for the post-GWAS functional characterization of cancer risk loci

scientific article published in June 2011

Profiling signatures of ovarian cancer tumour suppression using 2D-DIGE and 2D-LC-MS/MS with tandem mass tagging.

scientific article

Progesterone receptor gene polymorphisms and risk of endometriosis: results from an international collaborative effort

scientific article

Progesterone receptor variation and risk of ovarian cancer is limited to the invasive endometrioid subtype: results from the Ovarian Cancer Association Consortium pooled analysis

scientific article published on 22 January 2008

Prognostic gene expression signature for high-grade serous ovarian cancer

scientific article published on 27 May 2020

Prognostic value of estrogen receptor and progesterone receptor tumor expression in Danish ovarian cancer patients: from the 'MALOVA' ovarian cancer study.

scientific article published in November 2007

Prostate cancer reactivates developmental epigenomic programs during metastatic progression

scientific article published on 20 July 2020

Prostate cancer susceptibility polymorphism rs2660753 is not associated with invasive ovarian cancer

scientific article

Protein expression levels of carcinoembryonic antigen (CEA) in Danish ovarian cancer patients: from the Danish 'MALOVA'ovarian cancer study.

scientific article published in August 2008

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis. UKCCCR Familial Ovarian Cancer Study Group.

scientific article published in March 1996

Rare Germline Genetic Variants and the Risks of Epithelial Ovarian Cancer

scientific article published on 19 October 2020

Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study.

scientific article published on 13 November 2010

Risk models for familial ovarian and breast cancer

scientific article published on 01 February 2000

Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10

scientific article published on 22 November 2013

Risk of ovarian cancer in women with first-degree relatives with cancer

scientific article published in January 2009

Robust Tests for Additive Gene-Environment Interaction in Case-Control Studies Using Gene-Environment Independence

scientific article published on 14 June 2017

Role of common genetic variants in ovarian cancer susceptibility and outcome: progress to date from the Ovarian Cancer Association Consortium (OCAC).

scientific article published on April 2012

Role of genetic polymorphisms and ovarian cancer susceptibility

scientific article published on 04 February 2009

STK15 polymorphisms and association with risk of invasive ovarian cancer.

scientific article published in October 2004

Screening for theBRCA1-ins6kbEx13mutation: potential for misdiagnosis

Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer

scientific article

Serum peptide profiling using MALDI mass spectrometry: avoiding the pitfalls of coated magnetic beads using well-established ZipTip technology.

scientific article published in September 2007

Shared genetics underlying epidemiological association between endometriosis and ovarian cancer

scientific article published on 30 July 2015

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer

scientific article published on 10 March 2009

Somatic and germline mutations of the BRCA2 gene in sporadic ovarian cancer

scientific article published on 01 August 1996

Somatic mitochondrial DNA mutations in primary and metastatic ovarian cancer

scientific article published on 30 August 2006

Src as a novel therapeutic target for endometriosis

scientific article

Stromal Expression of Fibroblast Activation Protein Alpha (FAP) Predicts Platinum Resistance and Shorter Recurrence in patients with Epithelial Ovarian Cancer

scientific article published on 21 October 2014

Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer

scientific article published on 20 June 2019

Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group

scientific article published on 01 February 1999

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer

scientific article published in April 2007

Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer

scientific article

Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer

scientific article published on 24 February 2009

Targeting Src in endometriosis-associated ovarian cancer

scientific article published on 15 August 2016

Telomere structure and maintenance gene variants and risk of five cancer types

scientific article published on 15 December 2016

The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin

scientific article published on May 2016

The Effects of Common Genetic Variants in Oncogenes on Ovarian Cancer Survival

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

scientific article published on 01 November 2019

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

scientific article published on 03 October 2016

The PAX8 cistrome in epithelial ovarian cancer

scientific article published on 27 November 2017

The association between socioeconomic status and tumour stage at diagnosis of ovarian cancer: A pooled analysis of 18 case-control studies

scientific article published on 3 February 2016

The clonal evolution of metastases from primary serous epithelial ovarian cancers

scientific article published in April 2009

The contribution of BRCA1 and BRCA2 to ovarian cancer

scientific article published on 10 February 2009

The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population

scientific article

The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes

scientific article

The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators

article

The genetics of inherited breast cancer

scientific article

The inherited genetics of ovarian and endometrial cancer

scientific article

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

scientific article published on 8 March 2011

The sex hormone system in carriers of BRCA1/2 mutations: a case-control study.

scientific article published on 17 October 2013

Three-dimensional in vitro cell biology models of ovarian and endometrial cancer.

scientific article

Transcriptomic Characterization of Endometrioid, Clear Cell, and High-Grade Serous Epithelial Ovarian Carcinoma

scientific article published on 02 July 2018

Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene

scientific article

Use of common analgesic medications and ovarian cancer survival: results from a pooled analysis in the Ovarian Cancer Association Consortium

scientific article published on 28 March 2017

Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium

scientific article published on 06 January 2009

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

scientific article published in PLoS ONE

Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer

scientific article published on 16 April 2014

Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

scientific article published on 01 January 1997

Vascular endothelial growth factor gene polymorphisms and ovarian cancer survival

scientific article published in December 2010

Vitamin D receptor rs2228570 polymorphism and invasive ovarian carcinoma risk: pooled analysis in five studies within the Ovarian Cancer Association Consortium

scientific article

p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study

scientific article published on 22 March 2023

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology

scientific article published on 21 August 2018

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