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List of works by Katsuyuki Hotta

A Randomized Phase II Study of a Combination of Docetaxel and S-1 versus Docetaxel Monotherapy in Patients with Non-small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy: Results of Okayama Lung Cancer Study Group (OLCSG) Trial 0

A case of advanced non-small-cell lung cancer who responded slowly to gefitinib monotherapy after long-term disease stabilization

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A definite case of (L)-carbocisteine-induced pneumonia with CATCH22 syndrome

scientific article published on January 2013

A new human lung adenocarcinoma cell line harboring the EML4-ALK fusion gene

scientific article published on 28 August 2014

A phase I and pharmacological study of amrubicin and topotecan in patients of small-cell lung cancer with relapsed or extensive-disease small-cell lung cancer

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A phase I study and pharmacokinetics of irinotecan (CPT-11) and paclitaxel in patients with advanced non-small cell lung cancer

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A phase I study of 3-day topotecan and cisplatin in elderly patients with small-cell lung cancer

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A phase I study of S-1 with concurrent thoracic radiotherapy in elderly patients with localized advanced non-small cell lung cancer

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A phase I study of combination S-1 plus cisplatin chemotherapy with concurrent thoracic radiation for locally advanced non-small cell lung cancer

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A phase II study of S-1 chemotherapy with concurrent thoracic radiotherapy in elderly patients with locally advanced non-small-cell lung cancer: the Okayama Lung Cancer Study Group Trial 0801.

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A phase II study of amrubicin and topotecan combination therapy in patients with relapsed or extensive-disease small-cell lung cancer: Okayama Lung Cancer Study Group Trial 0401.

scientific article published on 18 February 2011

A phase II study of cisplatin plus S-1 with concurrent thoracic radiotherapy for locally advanced non-small-cell lung cancer: the Okayama Lung Cancer Study Group Trial 0501.

scientific article published on 8 November 2014

A phase II study of topotecan and cisplatin with sequential thoracic radiotherapy in elderly patients with small-cell lung cancer: Okayama Lung Cancer Study Group 0102.

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A phase II trial of carboplatin plus S-1 for elderly patients with advanced non-small-cell lung cancer with wild-type epidermal growth factor receptor: The Okayama Lung Cancer Study Group Trial 1202.

scientific article published on 12 August 2017

A phase II trial of cisplatin and irinotecan alternating with doxorubicin, cyclophosphamide and etoposide in previously untreated patients with extensive-disease small-cell lung cancer

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A phase II trial of erlotinib monotherapy in pretreated patients with advanced non-small cell lung cancer who do not possess active EGFR mutations: Okayama Lung Cancer Study Group trial 0705.

scientific article published in January 2010

A survey of Japanese thoracic oncologists' perception of diagnostic and treatment strategies for EGFR mutant or EML4-ALK fusion non-small cell lung cancer

scientific article published in December 2014

Advances in our understanding of postoperative adjuvant chemotherapy in resectable non-small-cell lung cancer

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An overview of 48 elderly-specific clinical trials of systemic chemotherapy for advanced non-small cell lung cancer

scientific article published in October 2004

Association between poor performance status and risk for toxicity during erlotinib monotherapy in Japanese patients with non-small cell lung cancer: Okayama Lung Cancer Study Group experience

scientific article published on 22 April 2010

Association of the benefit from gefitinib monotherapy with smoking status in Japanese patients with non-small-cell lung cancer

scientific article published on 15 May 2008

Benefits and Adverse Events Among Elderly Patients Receiving Concurrent Chemoradiotherapy for Locally Advanced Non-small Cell Lung Cancer: Analysis of the Okayama Lung Cancer Study Group Trial 0007

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Cisplatin-induced hyponatremia in malignancy: comparison between brand-name and generic formulation

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Clinical factors affecting acquired resistance to gefitinib in previously treated Japanese patients with advanced nonsmall cell lung cancer

scientific article published in October 2006

Clinical outcome in patients with leptomeningeal metastasis from non-small cell lung cancer: Okayama Lung Cancer Study Group

scientific article published on 7 April 2012

Clinical significance of epidermal growth factor receptor gene mutations on treatment outcome after first-line cytotoxic chemotherapy in Japanese patients with non-small cell lung cancer

scientific article published in July 2007

Clustered incidence of acute promyelocytic leukemia during gefitinib treatment for non-small-cell lung cancer: experience at a single institution

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Comparison of the incidence and pattern of interstitial lung disease during erlotinib and gefitinib treatment in Japanese Patients with non-small cell lung cancer: the Okayama Lung Cancer Study Group experience

scientific article published in February 2010

Comprehensive analysis of EGFR signaling pathways in Japanese patients with non-small cell lung cancer

scientific article published on 31 January 2009

Cure- or Care-Oriented Regimen for Stage III Non–Small-Cell Lung Cancer?

Desire for information and involvement in treatment decisions: lung cancer patients' preferences and their physicians' perceptions: results from Okayama Lung Cancer Study Group Trial 0705.

scientific article published in October 2010

Development of a skin rash within the first week and the therapeutic effect in afatinib monotherapy for EGFR-mutant non-small cell lung cancer (NSCLC): Okayama Lung Cancer Study Group experience

scientific article published on 31 March 2016

Discomfort during bronchoscopy performed after endobronchial intubation with fentanyl and midazolam: a prospective study

scientific article published on 23 February 2017

Downregulation of TBXAS1 in an iron-induced malignant mesothelioma model

scientific article published on 24 July 2015

EGFR Mutation, But Not Sex and Smoking, Is Independently Associated with Favorable Prognosis of Gefitinib-treated Patients with Lung Adenocarcinoma

Effect of AZD1480 in an epidermal growth factor receptor-driven lung cancer model

scientific article published on 29 October 2013

Effect of gefitinib ('Iressa', ZD1839) on brain metastases in patients with advanced non-small-cell lung cancer

scientific article published in November 2004

Efficacy of multimodal treatment for leptomeningeal metastases in a lung cancer harboring an EGFR mutation

scientific article published on 22 March 2016

Endobronchial ultrasound-guided transbronchial biopsy with or without a guide sheath for diagnosis of lung cancer

scientific article published on 13 November 2014

Endobronchial ultrasound-guided transbronchial needle aspiration of hilar and mediastinal lymph nodes detected on 18F-fluorodeoxyglucose positron emission tomography/computed tomography

scientific article published on 22 March 2016

Epidermal Growth Factor Receptor Mutation Status and Adjuvant Chemotherapy With Uracil-Tegafur for Adenocarcinoma of the Lung

Epidermal growth factor receptor mutation, but not sex and smoking, is independently associated with favorable prognosis of gefitinib-treated patients with lung adenocarcinoma

scientific article published in February 2008

Establishment of pemetrexed-resistant non-small cell lung cancer cell lines

scientific article published on 24 June 2011

Factor associated with failure to administer subsequent treatment after progression in the first-line chemotherapy in EGFR-mutant non-small cell lung cancer: Okayama Lung Cancer Study Group experience

scientific article published on 16 March 2014

Fatal Candida septic shock during systemic chemotherapy in lung cancer patient receiving corticosteroid replacement therapy for hypopituitarism: a case report

scientific article published on 19 March 2014

First-Line Pembrolizumab Versus Chemotherapy in Metastatic Non-Small-Cell Lung Cancer: KEYNOTE-024 Japan Subset

scientific article published on 14 September 2020

Gefitinib ('Iressa', ZD1839) may restore chemosensitivity in NSCLC patients?

scientific article published in January 2005

Gefitinib Combined With Standard Chemoradiotherapy in EGFR-Mutant Locally Advanced Non-Small-Cell Lung Cancer: The LOGIK0902/OLCSG0905 Intergroup Study Protocol

scientific article published on 18 August 2015

Gefitinib induces premature senescence in non-small cell lung cancer cells with or without EGFR gene mutation.

scientific article published on February 2007

Gefitinib should be cautiously administered to poor performance status patients with non-small-cell lung cancer: results from a prospective feasibility study

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Identification of epigenetic aberrant promoter methylation in serum DNA is useful for early detection of lung cancer.

scientific article published in February 2005

Impact of HER2 gene and protein status on the treatment outcome of cisplatin-based chemoradiotherapy for locally advanced non-small cell lung cancer

scientific article published in May 2008

Impact of body surface area on survival in EGFR-mutant non-small cell lung cancer patients treated with gefitinib monotherapy: observational study of the Okayama Lung Cancer Study Group 0703.

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Impact of physical size on gefitinib efficacy in patients with non-small cell lung cancer harboring EGFR mutations

scientific article published in July 2013

Influence of the timing of tumor regression after the initiation of chemoradiotherapy on prognosis in patients with limited-disease small-cell lung cancer achieving objective response

scientific article published on 31 July 2012

Interstitial lung disease in Japanese patients with non-small cell lung cancer receiving gefitinib: an analysis of risk factors and treatment outcomes in Okayama Lung Cancer Study Group

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Invasive mucinous adenocarcinoma mimicking organizing pneumonia associated with Mycobacterium fortuitum infection

scientific article published on 15 December 2014

Large cell neuroendocrine carcinoma of the mediastinum

scientific article published on July 2010

Magnitude of the benefit of progression-free survival as a potential surrogate marker in phase 3 trials assessing targeted agents in molecularly selected patients with advanced non-small cell lung cancer: systematic review

scientific article published on 16 March 2015

Meta-analysis of randomized clinical trials comparing Cisplatin to Carboplatin in patients with advanced non-small-cell lung cancer

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Non-Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases

scientific article published on 30 December 2015

Paradoxical Clinical Effects of Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitors for Acute Myelogenous Leukemia

Phase I study of irinotecan and amrubicin in patients with advanced non-small-cell lung cancer.

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Phase II Study of the EGFR-TKI Rechallenge With Afatinib in Patients With Advanced NSCLC Harboring Sensitive EGFR Mutation Without T790M: Okayama Lung Cancer Study Group Trial OLCSG 1403.

scientific article published on 9 July 2016

Phase II trial of gefitinib in combination with bevacizumab as first-line therapy for advanced non-small cell lung cancer with activating EGFR gene mutations: the Okayama Lung Cancer Study Group Trial 1001.

scientific article published in March 2015

Phase III trial comparing docetaxel and cisplatin combination chemotherapy with mitomycin, vindesine, and cisplatin combination chemotherapy with concurrent thoracic radiotherapy in locally advanced non-small-cell lung cancer: OLCSG 0007.

scientific article published on 7 June 2010

Pilot evaluation of a HER2 testing in non-small-cell lung cancer

scientific article published on 03 December 2019

Potential influence of being overweight on the development of hepatic dysfunction in Japanese patients with EGFR-mutated non-small cell lung cancer undergoing gefitinib monotherapy: the Okayama Lung Cancer Study Group experience

scientific article published on 2 September 2016

Progression-free survival and overall survival in phase III trials of molecular-targeted agents in advanced non-small-cell lung cancer

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Protocol Design for the Bench to Bed Trial in Alectinib-Refractory Non-Small-Cell Lung Cancer Patients Harboring the EML4-ALK Fusion Gene (ALRIGHT/OLCSG1405).

scientific article published on 2 June 2016

Randomized study comparing mannitol with furosemide for the prevention of cisplatin-induced renal toxicity in non-small cell lung cancer: The OLCSG1406 trial

scientific article published on 03 September 2020

Rapid on-site evaluation with BIOEVALUATOR(®) during endobronchial ultrasound-guided transbronchial needle aspiration for diagnosing pulmonary and mediastinal diseases

scientific article published on January 2014

Reappraisal of short-term low-volume hydration in cisplatin-based chemotherapy: results of a prospective feasibility study in advanced lung cancer in the Okayama Lung Cancer Study Group Trial 1002.

scientific article published on 29 September 2013

Reappraisal of short-term low-volume hydration in cisplatin-based chemotherapy; hoping for it as a public domain

scientific article published on 28 April 2015

Recent improvement in lung cancer screening: a comparison of the results carried out in two different time periods

scientific article published in June 2006

Recent improvement in the survival of patients with advanced nonsmall cell lung cancer enrolled in phase III trials of first-line, systemic chemotherapy

scientific article published on March 2007

Relationship between epidermal growth factor receptor gene mutations and the severity of adverse events by gefitinib in patients with advanced non-small cell lung cancer

scientific article published on 28 February 2006

Remarkable shrinkage of sarcomatoid renal cell carcinoma with single-agent gemcitabine

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Role of adjuvant chemotherapy in patients with resected non-small-cell lung cancer: reappraisal with a meta-analysis of randomized controlled trials

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Role of early serial change in serum carcinoembryonic antigen levels as a predictive marker for radiological response to gefitinib in Japanese patients with non-small cell lung cancer.

scientific article published in May 2007

Role of survival post-progression in phase III trials of systemic chemotherapy in advanced non-small-cell lung cancer: a systematic review

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Safety and discomfort during bronchoscopy performed under sedation with fentanyl and midazolam: a prospective study

scientific article published on 5 July 2016

Safety and efficacy of gefitinib treatment in elderly patients with non-small-cell lung cancer: Okayama Lung Cancer Study Group experience

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Second primary cancer in survivors of locally advanced non-small cell lung cancer treated with concurrent chemoradiation followed by surgery

scientific article published on 2 February 2018

Sex difference in the influence of smoking status on the responsiveness to gefitinib monotherapy in adenocarcinoma of the lung: Okayama Lung Cancer Study Group experience

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Short-term low-volume hydration in cisplatin-based chemotherapy for patients with lung cancer: the second prospective feasibility study in the Okayama Lung Cancer Study Group Trial 1201.

scientific article published on 21 June 2015

Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer

scientific article published on 15 January 2014

Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells

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Systemic tumor embolism mimicking gefitinib ('IRESSA')-induced interstitial lung disease in a patient with lung cancer

scientific article published in September 2005

The combination effect of amrubicin with cisplatin or irinotecan for small-cell lung cancer cells.

scientific article published on April 2006

Three-Arm Randomized Trial of Sodium Alginate for Preventing Radiation-Induced Esophagitis in Locally Advanced Non-Small Cell Lung Cancer Receiving Concurrent Chemoradiotherapy: The OLCSG1401 Study Protocol.

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Time to progression as a surrogate marker for overall survival in patients with advanced non-small cell lung cancer

scientific article published on March 2009

Treatment-related death in patients with small-cell lung cancer in phase III trials over the last two decades

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Triple combination chemotherapy with cisplatin, docetaxel, and irinotecan for advanced non-small cell lung cancer: a phase I/II trial.

scientific article published on January 2007

Triplet therapy with afatinib, cetuximab, and bevacizumab induces deep remission in lung cancer cells harboring EGFR T790M in vivo

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Twenty-seven years of phase III trials for patients with extensive disease small-cell lung cancer: disappointing results

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Usefulness of cumulative smoking dose for identifying the EGFR mutation and patients with non-small-cell lung cancer for gefitinib treatment

scientific article published on 2 July 2009

Whole blood interferon-gamma assay for baseline tuberculosis screening among Japanese healthcare students

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[A relapse of small-cell lung cancer ten years after concomitant chemoradiotherapy followed by high-dose chemotherapy with autologous peripheral blood stem cell transfusion].

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