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List of works by Dirk Reinhardt

1-(5-Carboxyindol-1-yl)propan-2-one Inhibitors of Human Cytosolic Phospholipase A2α: Effect of Substituents in Position 3 of the Indole Scaffold on Inhibitory Potency, Metabolic Stability, Solubility, and Bioavailability ⬇️

scientific article published on November 10, 2010

ABC transporter ABCA3 is expressed in acute myeloid leukemia blast cells and participates in vesicular transport

scientific article

Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia

scientific article published on 28 November 2012

Acute leukemias in children with Down syndrome

scientific article published on February 2008

Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).

scientific article

An effective modestly intensive re-induction regimen with bortezomib in relapsed or refractory paediatric acute lymphoblastic leukaemia

scientific article published on 20 April 2018

Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target ⬇️

scientific article published on September 3, 2012

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia

scientific article

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

scientific article

Clinical implications of FLT3 mutations in pediatric AML.

scientific article published on 15 August 2006

Clinical picture and differential diagnosis of cardiomyopathy and myocarditis ⬇️

scientific article published on April 15, 1998

Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

scientific article

Current controversies: which patients with acute myeloid leukaemia should receive a bone marrow transplantation?--a European view

scientific article

Development of a curative treatment within the AML-BFM studies ⬇️

scientific article published on May 22, 2013

Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis

scientific article

Differentially expressed miRNAs in cytogenetic and molecular subtypes of pediatric acute myeloid leukemia ⬇️

scientific article published on August 4, 2011

Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia?

scientific article published on 01 June 2006

Engagement of SIRPα inhibits growth and induces programmed cell death in acute myeloid leukemia cells

scientific article

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

scientific article

Gene expression profiles associated with pediatric relapsed AML.

scientific article

Genetic prognostic factors in childhood acute myeloid leukemia ⬇️

scientific article published on July 20, 2012

Granulocyte colony-stimulating factor (G-CSF) treatment of childhood acute myeloid leukemias that overexpress the differentiation-defective G-CSF receptor isoform IV is associated with a higher incidence of relapse

scientific article

Hemoglobin F in myelodysplastic syndrome ⬇️

scientific article published on March 1, 1998

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study

scientific article

High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia ⬇️

scientific article published on July 11, 2012

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

scholarly article

Improved outcome of pediatric patients with acute megakaryoblastic leukemia in the AML-BFM 04 trial

scientific article published on 28 April 2015

Infectious complications in pediatric acute myeloid leukemia: analysis of the prospective multi-institutional clinical trial AML-BFM 93 ⬇️

scientific article published on January 1, 2004

Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators

scientific article published on 09 September 2021

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

scientific article

LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia

scientific article

Long term survival in children with acute leukaemia and complications requiring mechanical ventilation

scientific article

MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia

scientific article published on 24 June 2016

Minimising the long-term adverse effects of childhood leukaemia therapy

scientific article

Mutated WT1, FLT3-ITD, and NUP98-NSD1 Fusion in Various Combinations Define a Poor Prognostic Group in Pediatric Acute Myeloid Leukemia

scientific article published on 30 July 2019

NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern ⬇️

scientific article published on 02 August 2011

Normal karyotype is a poor prognostic factor in myeloid leukemia of Down syndrome: a retrospective, international study.

scientific article published on 09 August 2013

Novel RUNX1 isoforms determine the fate of acute myeloid leukemia cells by controlling CD56 expression

scientific article

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.

scientific article

PHF6 mutations in paediatric acute myeloid leukaemia

scientific article published on 21 December 2015

Paediatric palliative home care in areas of Germany with low population density and long distances: a questionnaire survey with general paediatricians

scientific article

Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group.

scientific article

Phase I dose-escalation study of volasertib in pediatric patients with acute leukemia or advanced solid tumors

scientific article published on 05 July 2019

Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study

scientific article

Prospective validation of a new method of monitoring minimal residual disease in childhood acute myelogenous leukemia

scientific article published on 11 December 2014

Quality management in implementing specialist pediatric palliative home care in Lower Saxony, Germany ⬇️

scientific article published on May 12, 2012

RUNX1 mutation has no prognostic significance in paediatric AML: a retrospective study of the AML-BFM study group

scientific article published in 2023

Recurrent deletions of IKZF1 in pediatric acute myeloid leukemia

scientific article published on 11 June 2015

Subtype prediction in pediatric acute myeloid leukemia: classification using differential network rank conservation revisited

scientific article published on 23 September 2015

The prognostic significance of early treatment response in pediatric relapsed acute myeloid leukemia: results of the international study Relapsed AML 2001/01

scientific article

The role of matched sibling donor allogeneic stem cell transplantation in pediatric high-risk acute myeloid leukemia: results from the AML-BFM 98 study

scientific article published on 20 September 2011

The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells ⬇️

scientific article published on December 29, 2011

Treatment and prognostic impact of transient leukemia in neonates with Down syndrome

scientific article

miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia

scientific article

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