List of works - Roberto Gherzi

"HepG2/erythroid/brain" type glucose transporter (GLUT1) is highly expressed in human epidermis: keratinocyte differentiation affects GLUT1 levels in reconstituted epidermis

scientific article published on March 1, 1992

A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery

scientific article

AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

scientific article

Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation

scientific article

Assignment of the tenascin-R gene (Tnr) to mouse chromosome 4 band E2 by fluorescence in situ hybridization; refinement of the human TNR location to chromosome 1q24.

scientific article

Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease

scientific article

Glucose starvation and glycosylation inhibitors reduce insulin receptor gene expression: Characterization and potential mechanism in human cells ⬇️

scientific article published on June 15, 1990

H19 long noncoding RNA controls the mRNA decay promoting function of KSRP.

scientific article

How to control miRNA maturation?

scientific article

Human Tenascin Gene

scientific article (publication date: 17 February 1995)

Human tenascin gene. Structure of the 5'-region, identification, and characterization of the transcription regulatory sequences

scientific article

Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling

scientific article (publication date: 16 April 2007)

KSRP Promotes the Maturation of a Group of miRNA Precuresors

scientific article published on 01 January 2011

KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression

scientific article

KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells

scientific article published on 23 September 2009

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages

scientific article

Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP

scientific article

LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β

scientific article published on 29 April 2019

Multifactorial control of insulin receptor gene expression in human cell lines ⬇️

scientific article published on August 16, 1990

Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis

scientific article

Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets

scientific article

PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis

scientific article

Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding

scientific article

Rat tenascin-R gene: structure, chromosome location and transcriptional activity of promoter and exon 1

scientific journal article

Retraction: The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling

scientific article published on 16 November 2015

Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay

scientific article

The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

scientific article

The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling

scientific article

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

scientific article published on 20 May 2009

The human tenascin-R gene

scientific article

The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels

scientific journal article

The role of KSRP in mRNA decay and microRNA precursor maturation

scientific article published on 06 May 2010

The structure of the C-terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation

scientific article published in April 2007

miRNA-Mediated KHSRP Silencing Rewires Distinct Post-transcriptional Programs during TGF-β-Induced Epithelial-to-Mesenchymal Transition.

scientific article published on 6 July 2016

p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts

scientific journal article

List of works by Roberto Gherzi

"HepG2/erythroid/brain" type glucose transporter (GLUT1) is highly expressed in human epidermis: keratinocyte differentiation affects GLUT1 levels in reconstituted epidermis

A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery

AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation

Assignment of the tenascin-R gene (Tnr) to mouse chromosome 4 band E2 by fluorescence in situ hybridization; refinement of the human TNR location to chromosome 1q24.

Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease

Glucose starvation and glycosylation inhibitors reduce insulin receptor gene expression: Characterization and potential mechanism in human cells ⬇️

H19 long noncoding RNA controls the mRNA decay promoting function of KSRP.

How to control miRNA maturation?

Human Tenascin Gene

Human tenascin gene. Structure of the 5'-region, identification, and characterization of the transcription regulatory sequences

Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling

KSRP Promotes the Maturation of a Group of miRNA Precuresors

KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression

KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells

LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages

Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP

LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β

Multifactorial control of insulin receptor gene expression in human cell lines ⬇️

Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis

Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets

PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis

Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding

Rat tenascin-R gene: structure, chromosome location and transcriptional activity of promoter and exon 1

Retraction: The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling

Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay

The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B

The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs

The human tenascin-R gene

The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels

The role of KSRP in mRNA decay and microRNA precursor maturation

The structure of the C-terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation

miRNA-Mediated KHSRP Silencing Rewires Distinct Post-transcriptional Programs during TGF-β-Induced Epithelial-to-Mesenchymal Transition.

p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts