List of works - Richard M. Maizels

A family of diverse Kunitz inhibitors from Echinococcus granulosus potentially involved in host-parasite cross-talk.

scientific article

A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation

scientific article

Acquired immune heterogeneity and its sources in human helminth infection.

scientific article

Analyzing Airway Inflammation with Chemical Biology: Dissection of Acidic Mammalian Chitinase Function with a Selective Drug-like Inhibitor

scientific article

C-type lectins from the nematode parasites Heligmosomoides polygyrus and Nippostrongylus brasiliensis

scientific article published on 13 September 2009

CD11c depletion severely disrupts Th2 induction and development in vivo

scientific article

Characterization of a UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase with an unusual lectin domain from the platyhelminth parasite Echinococcus granulosus

scientific article published in September 2004

Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells

scientific article

Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage ⬇️

scientific article

Cohabitation in the Intestine: Interactions among Helminth Parasites, Bacterial Microbiota, and Host Immunity

scientific article

Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

scientific article published on 21 September 2018

Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection

scientific article (publication date: March 2015)

Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age

scientific article

Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms.

scientific article

Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections

scientific article

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

scientific article

Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection

scientific article

Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

scientific article

Full-length-enriched cDNA libraries from Echinococcus granulosus contain separate populations of oligo-capped and trans-spliced transcripts and a high level of predicted signal peptide sequences

scientific article

Generating EST libraries: trans-spliced cDNAs

scientific article

Heligmosomoides polygyrus Elicits a Dominant Nonprotective Antibody Response Directed against Restricted Glycan and Peptide Epitopes ⬇️

scientific article published on September 30, 2011

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

scientific article

Helminths in the gastrointestinal tract as modulators of immunity and pathology.

scientific article

Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function

scientific article

Human schistosomiasis in the post mass drug administration era.

scientific article

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

scientific article published on 07 October 2013

Immune regulation by helminth parasites: cellular and molecular mechanisms

scientific article (publication date: September 2003)

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

scientific article

Immuno-epidemiology of human Schistosoma haematobium infection: preferential IgG3 antibody responsiveness to a recombinant antigen dependent on age and parasite burden

scientific article

Infections and allergy - helminths, hygiene and host immune regulation

scientific article

Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection

scientific article

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

scientific article

Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human Infection

scientific article

Lymphatic filariasis and Brugia timori: prospects for elimination

scientific article

Macrobiota - helminths as active participants and partners of the microbiota in host intestinal homeostasis

scientific article

Macrophage origin limits functional plasticity in helminth-bacterial co-infection

scientific article

MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite Heligmosomoides polygyrus

scientific article

Parasite immunomodulation and polymorphisms of the immune system

scientific article

Prevention of birch pollen-related food allergy by mucosal treatment with multi-allergen-chimers in mice

scientific article

Real-time PCR detection of the HhaI tandem DNA repeat in pre- and post-patent Brugia malayi Infections: a study in Indonesian transmigrants

scientific article

Regulation of immunity and allergy by helminth parasites

scientific article published on 18 July 2019

Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum

scientific article

Regulatory T cells in human lymphatic filariasis: stronger functional activity in microfilaremics

scientific article

Regulatory and activated T cells in human Schistosoma haematobium infections

scientific article

Schistosome infection intensity is inversely related to auto-reactive antibody levels

scientific article

Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis

scientific article

Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants

article

Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity.

scientific article

Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites

scientific article

The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo

scientific article (publication date: February 2014)

The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory-secretory products.

scientific article

List of works by Richard M. Maizels

A family of diverse Kunitz inhibitors from Echinococcus granulosus potentially involved in host-parasite cross-talk.

A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation

Acquired immune heterogeneity and its sources in human helminth infection.

Analyzing Airway Inflammation with Chemical Biology: Dissection of Acidic Mammalian Chitinase Function with a Selective Drug-like Inhibitor

C-type lectins from the nematode parasites Heligmosomoides polygyrus and Nippostrongylus brasiliensis

CD11c depletion severely disrupts Th2 induction and development in vivo

Characterization of a UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase with an unusual lectin domain from the platyhelminth parasite Echinococcus granulosus

Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells

Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage ⬇️

Cohabitation in the Intestine: Interactions among Helminth Parasites, Bacterial Microbiota, and Host Immunity

Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection

Cytokine responses to Schistosoma haematobium in a Zimbabwean population: contrasting profiles for IFN-gamma, IL-4, IL-5 and IL-10 with age

Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms.

Exosomes and Other Extracellular Vesicles: The New Communicators in Parasite Infections

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection

Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

Full-length-enriched cDNA libraries from Echinococcus granulosus contain separate populations of oligo-capped and trans-spliced transcripts and a high level of predicted signal peptide sequences

Generating EST libraries: trans-spliced cDNAs

Heligmosomoides polygyrus Elicits a Dominant Nonprotective Antibody Response Directed against Restricted Glycan and Peptide Epitopes ⬇️

Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-β pathway

Helminths in the gastrointestinal tract as modulators of immunity and pathology.

Heterologous expression of the filarial nematode alt gene products reveals their potential to inhibit immune function

Human schistosomiasis in the post mass drug administration era.

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

Immune regulation by helminth parasites: cellular and molecular mechanisms

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

Immuno-epidemiology of human Schistosoma haematobium infection: preferential IgG3 antibody responsiveness to a recombinant antigen dependent on age and parasite burden

Infections and allergy - helminths, hygiene and host immune regulation

Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human Infection

Lymphatic filariasis and Brugia timori: prospects for elimination

Macrobiota - helminths as active participants and partners of the microbiota in host intestinal homeostasis

Macrophage origin limits functional plasticity in helminth-bacterial co-infection

MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite Heligmosomoides polygyrus

Parasite immunomodulation and polymorphisms of the immune system

Prevention of birch pollen-related food allergy by mucosal treatment with multi-allergen-chimers in mice

Real-time PCR detection of the HhaI tandem DNA repeat in pre- and post-patent Brugia malayi Infections: a study in Indonesian transmigrants

Regulation of immunity and allergy by helminth parasites

Regulatory T cells in human geohelminth infection suppress immune responses to BCG and Plasmodium falciparum

Regulatory T cells in human lymphatic filariasis: stronger functional activity in microfilaremics

Regulatory and activated T cells in human Schistosoma haematobium infections

Schistosome infection intensity is inversely related to auto-reactive antibody levels

Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis

Secreted venom allergen-like proteins of helminths: Conserved modulators of host responses in animals and plants

Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity.

Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites

The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo

The secretome of the filarial parasite, Brugia malayi: proteomic profile of adult excretory-secretory products.