List of works - Arkadiusz Orzechowski

A novel antioxidant-inhibited dexamethasone-mediated and caspase-3-independent muscle cell death.

scientific article published on December 2003

Abundance of some skeletal muscle mitochondrial proteins is associated with increased blood serum insulin in bovine fetuses

scientific article published on 7 May 2010

Bioactive substances of plant origin in food--impact on genomics

scientific article

Bisindolylmaleimide IX facilitates extrinsic and initiates intrinsic apoptosis in TNF-alpha-resistant human colon adenocarcinoma COLO 205 cells

scientific article

Bridging the Gap between Alzheimer's Disease and Alzheimer's-like Diseases in Animals ⬇️

scientific article published on 03 April 2019

Calcium homeostasis and ER stress in control of autophagy in cancer cells

scientific article published on 3 March 2015

Chapter 4: Regulation of Clusterin activity by calcium.

scientific article published on January 2009

Clusterin: the missing link in the calcium-dependent resistance of cancer cells to apoptogenic stimuli.

scientific article

Control of autophagy in cancer.

scientific article published on 10 March 2015

Cytokines and disease.

scientific article published on 14 September 2014

Delineation of signalling pathway leading to antioxidant-dependent inhibition of dexamethasone-mediated muscle cell death.

scientific article published in January 2003

Dexamethasone-mediated regulation of death and differentiation of muscle cells. Is hydrogen peroxide involved in the process?

scientific article published in May 2002

Diverse Action of Selected Statins on Skeletal Muscle Cells-An Attempt to Explain the Protective Effect of Geranylgeraniol (GGOH) in Statin-Associated Myopathy (SAM)

scientific article published on 16 May 2019

Elevated expression of NF-kappaB and Bcl-2 proteins in C2C12 myocytes during myogenesis is affected by PD98059, LY294002 and SB203580.

scientific article published on 7 April 2005

Ethylenediaminetetraacetic acid affects subcellular expression of clusterin protein in human colon adenocarcinoma COLO 205 cell line.

scientific article published on January 2007

FLIP--an enemy which might lose the battle against the specific inhibitors of translation

scientific article published in January 2005

FOXO1 and GSK-3β Are Main Targets of Insulin-Mediated Myogenesis in C2C12 Muscle Cells

scientific article published on 19 January 2016

Geranylgeraniol Prevents Statin-Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy.

scientific article published on 21 May 2018

IFN-alpha competes with TNF-alpha for STAT-1alpha; molecular basis for immune escape of human colon adenocarcinoma COLO 205 cells

scientific article published on 01 October 2007

Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease

scientific article

Leptin impairs myogenesis in C2C12 cells through JAK/STAT and MEK signaling pathways

scientific article

Lipid rafts in Alzheimer's disease

scientific article published in January 2012

Lipid rafts in anticancer therapy: Theory and practice (Review).

scientific article published on March 2008

Mitofusin 2 (Mfn2): a key player in insulin-dependent myogenesis in vitro

scientific article published on 09 November 2006

Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells.

scientific article published on January 2008

Not only insulin stimulates mitochondriogenesis in muscle cells, but mitochondria are also essential for insulin-mediated myogenesis

scientific article published on April 2006

Nucleofection of rat pheochromocytoma PC-12 cells with human mutated beta-amyloid precursor protein gene (APP-sw) leads to reduced viability, autophagy-like process, and increased expression and secretion of beta amyloid.

scientific article published on 10 March 2015

Oxidative Stress, Chronic Inflammation, and Amyloidoses

scientific article published on 08 September 2019

Preconditioning with millimolar concentrations of vitamin C or N-acetylcysteine protects L6 muscle cells insulin-stimulated viability and DNA synthesis under oxidative stress.

scientific article published in August 2002

Preincubation with bFGF but not sodium ascorbate improves efficiency of autologous transplantation of muscle-derived cells into urethral wall

scientific article published on 4 February 2009

Preincubation with sodium ascorbate potentiates insulin-dependent PKB/Akt and c-Jun phosphorylation in L6 rat myoblasts challenged with reactive oxygen/nitrogen species

scientific article

Preliminary Study on Clusterin Protein (sCLU) Expression in PC-12 Cells Overexpressing Wild-Type and Mutated (Swedish) genes Affected by Non-Steroid Isoprenoids and Water-Soluble Cholesterol ⬇️

article

Preliminary studies on phenothiazine-mediated reversal of multidrug resistance in mouse lymphoma and COLO 320 cells.

scientific article published on November 2005

Protective effect of sodium ascorbate on efficacy of intramuscular transplantation of autologous muscle-derived cells

scientific article published in January 2012

Role of transmembrane GTPases in mitochondrial morphology and activity

scientific article (publication date: 2007)

Sodium ascorbate and basic fibroblast growth factor protect muscle-derived cells from H2O2-induced oxidative stress

scientific article published in December 2006

Sodium butyrate sensitizes human colon adenocarcinoma COLO 205 cells to both intrinsic and TNF-alpha-dependent extrinsic apoptosis

scientific article

TNF- α and IFN-s-dependent muscle decay is linked to NF-κB- and STAT-1α-stimulated Atrogin1 and MuRF1 genes in C2C12 myotubes.

scientific article published on 17 December 2013

The Many Faces of Rap1 GTPase

scientific article published on 20 September 2018

The effect of silver nanoparticles (AgNPs) on proliferation and apoptosis of in ovo cultured glioblastoma multiforme (GBM) cells

scientific article

Ultrastructural evidence of amyloid beta-induced autophagy in PC12 cells

scientific article published on January 2009

Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells. ⬇️

scientific article

Verapamil treatment induces cytoprotective autophagy by modulating cellular metabolism

scientific article

Verapamil-induced autophagy-like process in colon adenocarcinoma COLO 205 cells; the ultrastructural studies.

scientific article

[Complex forms of immune insufficiency to some cytokines (TNF-alpha, interferons) in colorectal cancers as exemplified by the COLO 205 cell line. Mechanism of resistance with special reference to signaling proteins and cytokines]

scientific article published on 01 January 2004

[Muscle cell transplantations: the ups and downs]

scientific article published on 01 January 2005

List of works by Arkadiusz Orzechowski

A novel antioxidant-inhibited dexamethasone-mediated and caspase-3-independent muscle cell death.

Abundance of some skeletal muscle mitochondrial proteins is associated with increased blood serum insulin in bovine fetuses

Bioactive substances of plant origin in food--impact on genomics

Bisindolylmaleimide IX facilitates extrinsic and initiates intrinsic apoptosis in TNF-alpha-resistant human colon adenocarcinoma COLO 205 cells

Bridging the Gap between Alzheimer's Disease and Alzheimer's-like Diseases in Animals ⬇️

Calcium homeostasis and ER stress in control of autophagy in cancer cells

Chapter 4: Regulation of Clusterin activity by calcium.

Clusterin: the missing link in the calcium-dependent resistance of cancer cells to apoptogenic stimuli.

Control of autophagy in cancer.

Cytokines and disease.

Delineation of signalling pathway leading to antioxidant-dependent inhibition of dexamethasone-mediated muscle cell death.

Dexamethasone-mediated regulation of death and differentiation of muscle cells. Is hydrogen peroxide involved in the process?

Diverse Action of Selected Statins on Skeletal Muscle Cells-An Attempt to Explain the Protective Effect of Geranylgeraniol (GGOH) in Statin-Associated Myopathy (SAM)

Elevated expression of NF-kappaB and Bcl-2 proteins in C2C12 myocytes during myogenesis is affected by PD98059, LY294002 and SB203580.

Ethylenediaminetetraacetic acid affects subcellular expression of clusterin protein in human colon adenocarcinoma COLO 205 cell line.

FLIP--an enemy which might lose the battle against the specific inhibitors of translation

FOXO1 and GSK-3β Are Main Targets of Insulin-Mediated Myogenesis in C2C12 Muscle Cells

Geranylgeraniol Prevents Statin-Dependent Myotoxicity in C2C12 Muscle Cells through RAP1 GTPase Prenylation and Cytoprotective Autophagy.

IFN-alpha competes with TNF-alpha for STAT-1alpha; molecular basis for immune escape of human colon adenocarcinoma COLO 205 cells

Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease

Leptin impairs myogenesis in C2C12 cells through JAK/STAT and MEK signaling pathways

Lipid rafts in Alzheimer's disease

Lipid rafts in anticancer therapy: Theory and practice (Review).

Mitofusin 2 (Mfn2): a key player in insulin-dependent myogenesis in vitro

Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells.

Not only insulin stimulates mitochondriogenesis in muscle cells, but mitochondria are also essential for insulin-mediated myogenesis

Nucleofection of rat pheochromocytoma PC-12 cells with human mutated beta-amyloid precursor protein gene (APP-sw) leads to reduced viability, autophagy-like process, and increased expression and secretion of beta amyloid.

Oxidative Stress, Chronic Inflammation, and Amyloidoses

Preconditioning with millimolar concentrations of vitamin C or N-acetylcysteine protects L6 muscle cells insulin-stimulated viability and DNA synthesis under oxidative stress.

Preincubation with bFGF but not sodium ascorbate improves efficiency of autologous transplantation of muscle-derived cells into urethral wall

Preincubation with sodium ascorbate potentiates insulin-dependent PKB/Akt and c-Jun phosphorylation in L6 rat myoblasts challenged with reactive oxygen/nitrogen species

Preliminary Study on Clusterin Protein (sCLU) Expression in PC-12 Cells Overexpressing Wild-Type and Mutated (Swedish) genes Affected by Non-Steroid Isoprenoids and Water-Soluble Cholesterol ⬇️

Preliminary studies on phenothiazine-mediated reversal of multidrug resistance in mouse lymphoma and COLO 320 cells.

Protective effect of sodium ascorbate on efficacy of intramuscular transplantation of autologous muscle-derived cells

Role of transmembrane GTPases in mitochondrial morphology and activity

Sodium ascorbate and basic fibroblast growth factor protect muscle-derived cells from H2O2-induced oxidative stress

Sodium butyrate sensitizes human colon adenocarcinoma COLO 205 cells to both intrinsic and TNF-alpha-dependent extrinsic apoptosis

TNF- α and IFN-s-dependent muscle decay is linked to NF-κB- and STAT-1α-stimulated Atrogin1 and MuRF1 genes in C2C12 myotubes.

The Many Faces of Rap1 GTPase

The effect of silver nanoparticles (AgNPs) on proliferation and apoptosis of in ovo cultured glioblastoma multiforme (GBM) cells

Ultrastructural evidence of amyloid beta-induced autophagy in PC12 cells

Unappreciated Role of LDHA and LDHB to Control Apoptosis and Autophagy in Tumor Cells. ⬇️

Verapamil treatment induces cytoprotective autophagy by modulating cellular metabolism

Verapamil-induced autophagy-like process in colon adenocarcinoma COLO 205 cells; the ultrastructural studies.

[Complex forms of immune insufficiency to some cytokines (TNF-alpha, interferons) in colorectal cancers as exemplified by the COLO 205 cell line. Mechanism of resistance with special reference to signaling proteins and cytokines]

[Muscle cell transplantations: the ups and downs]