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List of works by Hans-Heinrich Hoffmann

A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry

scientific article published in 2021

A robust cell culture system supporting the complete life cycle of hepatitis B virus

scientific article published on 30 November 2017

A serpin shapes the extracellular environment to prevent influenza A virus maturation

scientific article

ATP-dependent effector-like functions of RIG-I-like receptors

scientific article

Auto-antibodies against type I IFNs in patients with life-threatening COVID-19

scientific article published on 24 September 2020

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

scientific article

Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals

scientific article published on 16 May 2020

Convergent antibody responses to SARS-CoV-2 in convalescent individuals

scientific article published on 18 June 2020

Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity

scientific article

Enhanced SARS-CoV-2 Neutralization by Secretory IgA in vitro

scientific article published on 09 September 2020

Enhanced SARS-CoV-2 neutralization by dimeric IgA

scientific article published on 07 December 2020

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

scientific article published on 22 July 2020

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

scientific article published on 11 September 2020

Genome-scale identification of SARS-CoV-2 and pan-coronavirus host factor networks

scientific article published on 08 October 2020

IFITM3 directly engages and shuttles incoming virus particles to lysosomes

scientific article published on 14 January 2019

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

scientific article published on 24 September 2020

Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines

scientific article published on 03 July 2019

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers ⬇️

scientific article published on September 6, 2011

Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion

scientific article

Interferons and viruses: an evolutionary arms race of molecular interactions

scientific article

Intrinsic Immunity Shapes Viral Resistance of Stem Cells

scientific article published on 12 December 2017

LY6E impairs coronavirus fusion and confers immune control of viral disease

scientific article published on 23 July 2020

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

scientific article published on 09 June 2020

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

scientific article published on 01 November 2020

Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism

scientific article published on 01 June 2020

Multifaceted activities of type I interferon are revealed by a receptor antagonist

scientific article

NS5A Promotes Constitutive Degradation of IP3R3 to Counteract Apoptosis Induced by Hepatitis C Virus

article

RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology

scientific article published on 24 July 2020

The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.

scientific article published on March 2017

Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies

scientific article published on 26 April 2016

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