List of works - Uwe Hansen

4-Phenylbutyric Acid Reduces Endoplasmic Reticulum Stress in Chondrocytes That Is Caused by Loss of the Protein Disulfide Isomerase ERp57

scientific article published on 29 October 2019

A Novel Histidine-Tryptophan-Ketoglutarate Formulation Ameliorates Intestinal Injury in a Cold Storage and ex vivo Warm Oxygenated Reperfusion Model in Rats

scientific article published on 04 March 2020

A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo

scientific article published on 4 January 2017

A matrilin-3 mutation associated with osteoarthritis does not affect collagen affinity but promotes the formation of wider cartilage collagen fibrils

scientific article

A novel MRI compatible mouse fracture model to characterize and monitor bone regeneration and tissue composition

scientific article published on 01 October 2020

A novel marker of tissue junctions, collagen XXII ⬇️

scientific article

A secreted variant of cartilage oligomeric matrix protein carrying a chondrodysplasia‐causing mutation (p.H587R) disrupts collagen fibrillogenesis ⬇️

scientific article published on 01 January 2011

Aberrations of dermal connective tissue in patients with cervical artery dissection (sCAD)

scientific article published on 14 March 2008

Age-related bone deterioration is diminished by disrupted collagen sensing in integrin α2β1 deficient mice

scientific article published on 13 May 2013

Allele-specific siRNA knockdown as a personalized treatment strategy for vascular Ehlers-Danlos syndrome in human fibroblasts

scientific article published on 28 October 2011

Analysis of Collagen-Binding Integrin Interactions with Supramolecular Aggregates of the Extracellular Matrix

scientific article published on 01 January 2019

Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI

scientific article published on 07 August 2020

Articular cartilage and sternal fibrocartilage respond differently to extended microgravity

scientific article published on 18 February 2019

Author Correction: The Staphylococcus aureus extracellular matrix protein (Emp) has a fibrous structure and binds to different extracellular matrices.

scientific article published on 25 May 2018

Blood-brain barrier properties in vitro depend on composition and assembly of endogenous extracellular matrices.

scientific article published on 6 April 2016

Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular Contents

scientific article published on 12 June 2020

Cartilage intermediate layer protein 2 (CILP-2) is expressed in articular and meniscal cartilage and down-regulated in experimental osteoarthritis.

scientific article

Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner

scientific article

Collagen XII interacts with avian tenascin-X through its NC3 domain

scientific article published on 21 July 2006

Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function.

scientific article

Cryopreservation of tendon tissue using dimethyl sulfoxide combines conserved cell vitality with maintained biomechanical features

scientific article published on 19 April 2019

Defective glycosylation of decorin and biglycan, altered collagen structure, and abnormal phenotype of the skin fibroblasts of an Ehlers-Danlos syndrome patient carrying the novel Arg270Cys substitution in galactosyltransferase I (beta4GalT-7)

scientific article

Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation

scientific article published in PLoS ONE

Discrete integration of collagen XVI into tissue-specific collagen fibrils or beaded microfibrils

scientific article (publication date: April 2003)

ER Stress During the Pubertal Growth Spurt Results in Impaired Long-Bone Growth in Chondrocyte-Specific ERp57 Knockout Mice.

scientific article published on 16 June 2015

Establishment of a matrix-associated transepithelial resistance invasion assay to precisely measure the invasive potential of synovial fibroblasts

scientific article

Functionalization of Clinically Approved MRI Contrast Agents for the Delivery of VEGF

scientific article published on 14 March 2019

In vivo evidence for a bridging role of a collagen V subtype at the epidermis-dermis interface

scientific article published on 22 March 2012

Increased Collagen Turnover Impairs Tendon Microstructure and Stability in Integrin α2β1-Deficient Mice

scientific article published on 18 April 2020

Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM1 is a basement membrane protein of the skin.

scientific article

Introducing Specificity to Iron Oxide Nanoparticle Imaging by Combining 57Fe-Based MRI and Mass Spectrometry

scientific article published on 02 October 2019

Isolating Crucial Steps in Induction of Infective Endocarditis With Preclinical Modeling of Host Pathogen Interaction

scientific article published on 18 June 2020

Lateral growth limitation of corneal fibrils and their lamellar stacking depend on covalent collagen cross-linking by transglutaminase-2 and lysyl oxidases, respectively

scientific article

Lipofuscin-dependent stimulation of microglial cells

scientific article published on 28 January 2019

Macromolecular specificity of collagen fibrillogenesis: fibrils of collagens I and XI contain a heterotypic alloyed core and a collagen I sheath

scientific article (publication date: 26 September 2003)

Mice lacking the extracellular matrix protein WARP develop normally but have compromised peripheral nerve structure and function

scientific journal article

Molecular properties and fibril ultrastructure of types II and XI collagens in cartilage of mice expressing exclusively the α1(IIA) collagen isoform

scientific article published on 07 October 2013

Phospholipid scramblase 1 is secreted by a lipid raft-dependent pathway and interacts with the extracellular matrix protein 1 in the dermal epidermal junction zone of human skin

scientific article

RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes.

scientific article published on 12 May 2014

SC1/hevin. An extracellular calcium-modulated protein that binds collagen I.

scientific article

Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells

scientific article published on 12 February 2014

Staphylococcus aureus isolates from chronic osteomyelitis are characterized by high host cell invasion and intracellular adaptation, but still induce inflammation.

scientific article

Sulforaphane Elicits Protective Effects in Intestinal Ischemia Reperfusion Injury

scientific article published on 22 July 2020

Supramolecular Organization of Collagen Fibrils in Healthy and Osteoarthritic Human Knee and Hip Joint Cartilage

scientific article

Supramolecular interactions in the dermo-epidermal junction zone: anchoring fibril-collagen VII tightly binds to banded collagen fibrils

scientific article published on 3 July 2008

Tenascin-C orchestrates an immune suppressive tumor microenvironment in oral squamous cell carcinoma

scientific article published on 14 July 2020

The Staphylococcus aureus extracellular matrix protein (Emp) has a fibrous structure and binds to different extracellular matrices

scientific article

The anchorless adhesin Eap (extracellular adherence protein) from Staphylococcus aureus selectively recognizes extracellular matrix aggregates but binds promiscuously to monomeric matrix macromolecules

scientific article published on 07 March 2006

The binding capacity of α1β1-, α2β1- and α10β1-integrins depends on non-collagenous surface macromolecules rather than the collagens in cartilage fibrils.

scientific article published on 10 February 2017

The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens

scientific article

The expanded collagen VI family: new chains and new questions

scientific article

The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis

scientific article

Three novel collagen VI chains, alpha4(VI), alpha5(VI), and alpha6(VI)

scientific article

Transport mechanisms and their pathology-induced regulation govern tyrosine kinase inhibitor delivery in rheumatoid arthritis

scientific article

Type XXVII collagen at the transition of cartilage to bone during skeletogenesis

scientific article

WARP interacts with collagen VI-containing microfibrils in the pericellular matrix of human chondrocytes

scientific article

WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan

scientific journal article

List of works by Uwe Hansen

4-Phenylbutyric Acid Reduces Endoplasmic Reticulum Stress in Chondrocytes That Is Caused by Loss of the Protein Disulfide Isomerase ERp57

A Novel Histidine-Tryptophan-Ketoglutarate Formulation Ameliorates Intestinal Injury in a Cold Storage and ex vivo Warm Oxygenated Reperfusion Model in Rats

A Novel Mouse Model of Staphylococcus aureus Vascular Graft Infection: Noninvasive Imaging of Biofilm Development in Vivo

A matrilin-3 mutation associated with osteoarthritis does not affect collagen affinity but promotes the formation of wider cartilage collagen fibrils

A novel MRI compatible mouse fracture model to characterize and monitor bone regeneration and tissue composition

A novel marker of tissue junctions, collagen XXII ⬇️

A secreted variant of cartilage oligomeric matrix protein carrying a chondrodysplasia‐causing mutation (p.H587R) disrupts collagen fibrillogenesis ⬇️

Aberrations of dermal connective tissue in patients with cervical artery dissection (sCAD)

Age-related bone deterioration is diminished by disrupted collagen sensing in integrin α2β1 deficient mice

Allele-specific siRNA knockdown as a personalized treatment strategy for vascular Ehlers-Danlos syndrome in human fibroblasts

Analysis of Collagen-Binding Integrin Interactions with Supramolecular Aggregates of the Extracellular Matrix

Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI

Articular cartilage and sternal fibrocartilage respond differently to extended microgravity

Author Correction: The Staphylococcus aureus extracellular matrix protein (Emp) has a fibrous structure and binds to different extracellular matrices.

Blood-brain barrier properties in vitro depend on composition and assembly of endogenous extracellular matrices.

Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular Contents

Cartilage intermediate layer protein 2 (CILP-2) is expressed in articular and meniscal cartilage and down-regulated in experimental osteoarthritis.

Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner

Collagen XII interacts with avian tenascin-X through its NC3 domain

Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function.

Cryopreservation of tendon tissue using dimethyl sulfoxide combines conserved cell vitality with maintained biomechanical features

Defective glycosylation of decorin and biglycan, altered collagen structure, and abnormal phenotype of the skin fibroblasts of an Ehlers-Danlos syndrome patient carrying the novel Arg270Cys substitution in galactosyltransferase I (beta4GalT-7)

Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation

Discrete integration of collagen XVI into tissue-specific collagen fibrils or beaded microfibrils

ER Stress During the Pubertal Growth Spurt Results in Impaired Long-Bone Growth in Chondrocyte-Specific ERp57 Knockout Mice.

Establishment of a matrix-associated transepithelial resistance invasion assay to precisely measure the invasive potential of synovial fibroblasts

Functionalization of Clinically Approved MRI Contrast Agents for the Delivery of VEGF

In vivo evidence for a bridging role of a collagen V subtype at the epidermis-dermis interface

Increased Collagen Turnover Impairs Tendon Microstructure and Stability in Integrin α2β1-Deficient Mice

Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM1 is a basement membrane protein of the skin.

Introducing Specificity to Iron Oxide Nanoparticle Imaging by Combining 57Fe-Based MRI and Mass Spectrometry

Isolating Crucial Steps in Induction of Infective Endocarditis With Preclinical Modeling of Host Pathogen Interaction

Lateral growth limitation of corneal fibrils and their lamellar stacking depend on covalent collagen cross-linking by transglutaminase-2 and lysyl oxidases, respectively

Lipofuscin-dependent stimulation of microglial cells

Macromolecular specificity of collagen fibrillogenesis: fibrils of collagens I and XI contain a heterotypic alloyed core and a collagen I sheath

Mice lacking the extracellular matrix protein WARP develop normally but have compromised peripheral nerve structure and function

Molecular properties and fibril ultrastructure of types II and XI collagens in cartilage of mice expressing exclusively the α1(IIA) collagen isoform

Phospholipid scramblase 1 is secreted by a lipid raft-dependent pathway and interacts with the extracellular matrix protein 1 in the dermal epidermal junction zone of human skin

RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes.

SC1/hevin. An extracellular calcium-modulated protein that binds collagen I.

Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells

Staphylococcus aureus isolates from chronic osteomyelitis are characterized by high host cell invasion and intracellular adaptation, but still induce inflammation.

Sulforaphane Elicits Protective Effects in Intestinal Ischemia Reperfusion Injury

Supramolecular Organization of Collagen Fibrils in Healthy and Osteoarthritic Human Knee and Hip Joint Cartilage

Supramolecular interactions in the dermo-epidermal junction zone: anchoring fibril-collagen VII tightly binds to banded collagen fibrils

Tenascin-C orchestrates an immune suppressive tumor microenvironment in oral squamous cell carcinoma

The Staphylococcus aureus extracellular matrix protein (Emp) has a fibrous structure and binds to different extracellular matrices

The anchorless adhesin Eap (extracellular adherence protein) from Staphylococcus aureus selectively recognizes extracellular matrix aggregates but binds promiscuously to monomeric matrix macromolecules

The binding capacity of α1β1-, α2β1- and α10β1-integrins depends on non-collagenous surface macromolecules rather than the collagens in cartilage fibrils.

The epidermal basement membrane is a composite of separate laminin- or collagen IV-containing networks connected by aggregated perlecan, but not by nidogens

The expanded collagen VI family: new chains and new questions

The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis

Three novel collagen VI chains, alpha4(VI), alpha5(VI), and alpha6(VI)

Transport mechanisms and their pathology-induced regulation govern tyrosine kinase inhibitor delivery in rheumatoid arthritis

Type XXVII collagen at the transition of cartilage to bone during skeletogenesis

WARP interacts with collagen VI-containing microfibrils in the pericellular matrix of human chondrocytes

WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan