List of works - Jack van Horssen

A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model

scientific article published on 11 July 2017

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

scientific article

Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy.

scientific article published on 23 March 2011

Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases

scientific article

Appearance of tissue transglutaminase in astrocytes in multiple sclerosis lesions: a role in cell adhesion and migration?

scientific article published on 20 August 2010

Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis

scientific article

CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis.

scientific article

Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions

scientific article published on April 2014

Cholinergic imbalance in the multiple sclerosis hippocampus

scientific article

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

scientific article

Differential expression of glucose-metabolizing enzymes in multiple sclerosis lesions

scientific article

Down-regulation of neuronal L1 cell adhesion molecule expression alleviates inflammatory neuronal injury

scientific article published on 20 August 2016

Enhanced number and activity of mitochondria in multiple sclerosis lesions

scientific article published in October 2009

Functions of lipid raft membrane microdomains at the blood-brain barrier

scientific article published on 30 May 2009

Glutathione in multiple sclerosis: more than just an antioxidant?

scientific article published on 19 May 2014

Heparan sulfate proteoglycan expression in cerebrovascular amyloid β deposits in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis (Dutch) brains ⬇️

scientific article published on December 1, 2001

Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders

scientific article

Inflammation and mitochondrial dysfunction: A vicious circle in neurodegenerative disorders?

scientific article published on 28 June 2017

Involvement and interplay of Parkin, PINK1, and DJ1 in neurodegenerative and neuroinflammatory disorders

scientific article published on 09 June 2012

MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet

scientific article

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

scientific article published on 4 March 2013

Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis

scientific article published on 24 December 2013

Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?

scientific article published on June 2010

Myelin alters the inflammatory phenotype of macrophages by activating PPARs.

scientific article published on 02 August 2013

Myelin basic protein synthesis is regulated by small non-coding RNA 715.

scientific article

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

scientific article published on March 2012

Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions ⬇️

scientific article published on July 29, 2010

Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

scientific article published on 13 September 2008

Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope?

scientific article published on April 2016

P-glycoprotein acts as an immunomodulator during neuroinflammation.

scientific article

Parkinson's disease-associated parkin colocalizes with Alzheimer's disease and multiple sclerosis brain lesions

scientific article

Preactive multiple sclerosis lesions offer novel clues for neuroprotective therapeutic strategies.

scientific article published on February 2011

Progressive multiple sclerosis: pathology and pathogenesis

scientific article published on 25 September 2012

Radical changes in multiple sclerosis pathogenesis

scientific article published on 27 June 2010

Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex

scientific article

Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes.

scientific article

Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

scientific article

Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier

scientific article

Spillage of bacterial products during colon surgery increases the risk of liver metastases development in a rat colon carcinoma model

scientific article published on 26 July 2018

The Role of ATP-Binding Cassette Transporters in Neuro-Inflammation: Relevance for Bioactive Lipids

scientific article published on 30 April 2012

The blood-brain barrier in cortical multiple sclerosis lesions

scientific article

The extracellular matrix in multiple sclerosis pathology

scientific article published on 13 September 2007

The molecular basis of neurodegeneration in multiple sclerosis

scientific article published on 16 August 2011

The role of mitochondria in axonal degeneration and tissue repair in MS ⬇️

scientific article published on June 21, 2012

Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology

scientific article

Visual pathway neurodegeneration winged by mitochondrial dysfunction.

scientific article

List of works by Jack van Horssen

A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model

Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system

Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy.

Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases

Appearance of tissue transglutaminase in astrocytes in multiple sclerosis lesions: a role in cell adhesion and migration?

Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis

CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis.

Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions

Cholinergic imbalance in the multiple sclerosis hippocampus

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

Differential expression of glucose-metabolizing enzymes in multiple sclerosis lesions

Down-regulation of neuronal L1 cell adhesion molecule expression alleviates inflammatory neuronal injury

Enhanced number and activity of mitochondria in multiple sclerosis lesions

Functions of lipid raft membrane microdomains at the blood-brain barrier

Glutathione in multiple sclerosis: more than just an antioxidant?

Heparan sulfate proteoglycan expression in cerebrovascular amyloid β deposits in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis (Dutch) brains ⬇️

Heparan sulphate proteoglycans in Alzheimer's disease and amyloid-related disorders

Inflammation and mitochondrial dysfunction: A vicious circle in neurodegenerative disorders?

Involvement and interplay of Parkin, PINK1, and DJ1 in neurodegenerative and neuroinflammatory disorders

MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis

Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?

Myelin alters the inflammatory phenotype of macrophages by activating PPARs.

Myelin basic protein synthesis is regulated by small non-coding RNA 715.

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions ⬇️

Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

Oxidative Stress and Antioxidants in Neurological Diseases: Is There Still Hope?

P-glycoprotein acts as an immunomodulator during neuroinflammation.

Parkinson's disease-associated parkin colocalizes with Alzheimer's disease and multiple sclerosis brain lesions

Preactive multiple sclerosis lesions offer novel clues for neuroprotective therapeutic strategies.

Progressive multiple sclerosis: pathology and pathogenesis

Radical changes in multiple sclerosis pathogenesis

Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex

Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes.

Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier

Spillage of bacterial products during colon surgery increases the risk of liver metastases development in a rat colon carcinoma model

The Role of ATP-Binding Cassette Transporters in Neuro-Inflammation: Relevance for Bioactive Lipids

The blood-brain barrier in cortical multiple sclerosis lesions

The extracellular matrix in multiple sclerosis pathology

The molecular basis of neurodegeneration in multiple sclerosis

The role of mitochondria in axonal degeneration and tissue repair in MS ⬇️

Therapeutic potential and biological role of endogenous antioxidant enzymes in multiple sclerosis pathology

Visual pathway neurodegeneration winged by mitochondrial dysfunction.