List of works - Lorenzo F Sempere

A Method for Conducting Highly Sensitive MicroRNA In Situ Hybridization and Immunohistochemical Analysis in Pancreatic Cancer ⬇️

scientific article published on 01 January 2013

A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome

scientific article

A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells

scientific article

Abstract LB-360: Fluorescence-based co-registration with protein markers reveals distinct cellular compartments for altered microRNA expression in solid tumors

Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer

scientific article

Automated Five-Color Multiplex Co-detection of MicroRNA and Protein Expression in Fixed Tissue Specimens

scientific article published on 01 January 2020

Celebrating 25 Years of MicroRNA Research: From Discovery to Clinical Application

article published in 2019

Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Patients with Lung Cancer ⬇️

scientific article published on May 16, 2013

Critical analysis of the potential for microRNA biomarkers in breast cancer management.

scientific article

Ductal tree ablation by local delivery of ethanol prevents tumor formation in an aggressive mouse model of breast cancer

scientific article published on 28 November 2019

Exosomal MicroRNAs in Breast Cancer towards Diagnostic and Therapeutic Applications

scientific article published on 24 June 2017

Expression of tumor suppressive microRNA-34a is associated with a reduced risk of bladder cancer recurrence

scientific article published on 29 December 2014

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

scientific article

Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors

scientific article published on 3 August 2010

Fully automated fluorescence-based four-color multiplex assay for co-detection of microRNA and protein biomarkers in clinical tissue specimens

scientific article published on 01 January 2014

Good things come in small packages: Therapeutic anti-tumor immunity induced by microRNA nanoparticles

scientific article published on September 2012

Integrating contextual miRNA and protein signatures for diagnostic and treatment decisions in cancer ⬇️

scientific article published on November 1, 2011

Involvement of microRNAs in lung cancer biology and therapy

scientific article

Loss of microRNA-21 leads to profound stromal remodeling and short survival in K-Ras-driven mouse models of pancreatic cancer

scientific article published on 10 May 2020

MIR21 is differentially expressed in the lymphoid tissue and modulated by stromal signalling in chronic lymphocytic leukaemia.

scientific article

MicroRNA-10b expression correlates with response to neoadjuvant therapy and survival in pancreatic ductal adenocarcinoma

scientific article

MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma

scientific article published on 01 May 2019

MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors

scientific article

MicroRNAs and the advent of vertebrate morphological complexity

scientific article

Phylogenetic distribution of microRNAs supports the basal position of acoel flatworms and the polyphyly of Platyhelminthes

scientific article published on 01 September 2007

Recent advances in miRNA-based diagnostic applications ⬇️

scientific article published on July 1, 2012

Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer ⬇️

scientific article published on February 3, 2012

Segment and fit thresholding: a new method for image analysis applied to microarray and immunofluorescence data.

scientific article

Shining the spotlight on shed KRAS in pancreatic cancer

scientific article published on 01 March 2008

Stromal expression of miR-21 identifies high-risk group in triple-negative breast cancer.

scientific article

Tantalum Oxide Nanoparticles as Versatile Contrast Agents for X-ray Computed Tomography

scientific article published on 13 February 2020

Tantalum oxide nanoparticles as versatile contrast agents for X-ray computed tomography

scientific article published on 25 March 2020

Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity

scientific article (publication date: July 2003)

The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster

scientific article (publication date: April 2002)

The phylogenetic distribution of metazoan microRNAs: insights into evolutionary complexity and constraint

scientific article published on November 2006

Tissue slide-based microRNA characterization of tumors: how detailed could diagnosis become for cancer medicine?

scientific article

Tumor-suppressive microRNAs in Lung cancer: diagnostic and therapeutic opportunities

scientific article published on 13 July 2009

UBE1L causes lung cancer growth suppression by targeting cyclin D1.

scientific article published on December 2008

Uncovering growth-suppressive MicroRNAs in lung cancer

scientific article published on February 2009

VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy

scientific article published on June 2014

VISTA is an immune checkpoint molecule for human T cells

scientific article

ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.

scientific article published on 14 December 2012

List of works by Lorenzo F Sempere

A Method for Conducting Highly Sensitive MicroRNA In Situ Hybridization and Immunohistochemical Analysis in Pancreatic Cancer ⬇️

A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome

A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells

Abstract LB-360: Fluorescence-based co-registration with protein markers reveals distinct cellular compartments for altered microRNA expression in solid tumors

Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancer

Automated Five-Color Multiplex Co-detection of MicroRNA and Protein Expression in Fixed Tissue Specimens

Celebrating 25 Years of MicroRNA Research: From Discovery to Clinical Application

Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Patients with Lung Cancer ⬇️

Critical analysis of the potential for microRNA biomarkers in breast cancer management.

Ductal tree ablation by local delivery of ethanol prevents tumor formation in an aggressive mouse model of breast cancer

Exosomal MicroRNAs in Breast Cancer towards Diagnostic and Therapeutic Applications

Expression of tumor suppressive microRNA-34a is associated with a reduced risk of bladder cancer recurrence

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors

Fully automated fluorescence-based four-color multiplex assay for co-detection of microRNA and protein biomarkers in clinical tissue specimens

Good things come in small packages: Therapeutic anti-tumor immunity induced by microRNA nanoparticles

Integrating contextual miRNA and protein signatures for diagnostic and treatment decisions in cancer ⬇️

Involvement of microRNAs in lung cancer biology and therapy

Loss of microRNA-21 leads to profound stromal remodeling and short survival in K-Ras-driven mouse models of pancreatic cancer

MIR21 is differentially expressed in the lymphoid tissue and modulated by stromal signalling in chronic lymphocytic leukaemia.

MicroRNA-10b expression correlates with response to neoadjuvant therapy and survival in pancreatic ductal adenocarcinoma

MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma

MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors

MicroRNAs and the advent of vertebrate morphological complexity

Phylogenetic distribution of microRNAs supports the basal position of acoel flatworms and the polyphyly of Platyhelminthes

Recent advances in miRNA-based diagnostic applications ⬇️

Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer ⬇️

Segment and fit thresholding: a new method for image analysis applied to microarray and immunofluorescence data.

Shining the spotlight on shed KRAS in pancreatic cancer

Stromal expression of miR-21 identifies high-risk group in triple-negative breast cancer.

Tantalum Oxide Nanoparticles as Versatile Contrast Agents for X-ray Computed Tomography

Tantalum oxide nanoparticles as versatile contrast agents for X-ray computed tomography

Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity

The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster

The phylogenetic distribution of metazoan microRNAs: insights into evolutionary complexity and constraint

Tissue slide-based microRNA characterization of tumors: how detailed could diagnosis become for cancer medicine?

Tumor-suppressive microRNAs in Lung cancer: diagnostic and therapeutic opportunities

UBE1L causes lung cancer growth suppression by targeting cyclin D1.

Uncovering growth-suppressive MicroRNAs in lung cancer

VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy

VISTA is an immune checkpoint molecule for human T cells

ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.