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List of works by James David Chappell

1101. Comparison of Clinical Characteristics and Demographics of GII.4 vs. Other GII Noroviruses Associated With Sporadic Acute Gastroenteritis in Children in Nashville, TN, 2012–2015

1112. Detection of Enteric Viruses in Children With Acute Gastroenteritis

995Comparing the Clinical Presentation of Viral Causes of Pediatric Acute Gastroenteritis.

scientific article published in December 2014

A Post-entry Step in the Mammalian Orthoreovirus Replication Cycle Is a Determinant of Cell Tropism ⬇️

scientific article published on October 26, 2010

A chimeric adenovirus vector encoding reovirus attachment protein sigma1 targets cells expressing junctional adhesion molecule 1.

scholarly article

A plasmid-based reverse genetics system for animal double-stranded RNA viruses.

scientific article published on April 2007

A single-amino-acid polymorphism in reovirus protein μ2 determines repression of interferon signaling and modulates myocarditis

scientific article published on 7 December 2011

An improved reverse genetics system for mammalian orthoreoviruses

scientific article

An mRNA Vaccine against SARS-CoV-2 - Preliminary Report

scientific article published on 14 July 2020

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

scientific article published on 06 April 2020

Association of Rotavirus Vaccination With Inpatient and Emergency Department Visits Among Children Seeking Care for Acute Gastroenteritis, 2010-2016

scientific article published on 04 September 2019

Characteristics of GII.4 Norovirus versus other Genotypes in Sporadic Pediatric Infections in Davidson County, Tennessee, USA

scientific article published on 15 July 2020

Clinical accuracy of a PLEX-ID flu device for simultaneous detection and identification of influenza viruses A and B.

scientific article published on 17 October 2012

Coccidioides, Cryptococcus, or Blastomyces? A Diagnostic Dilemma Encountered during Frozen Section Evaluation ⬇️

scientific article published on August 4, 2011

Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults

scientific article published on 14 July 2015

Community-acquired pneumonia requiring hospitalization among U.S. children

scientific article

Comparison of 2 Assays for Diagnosing Rotavirus and Evaluating Vaccine Effectiveness in Children with Gastroenteritis ⬇️

scientific article published on August 1, 2013

Comparison of three multiplex gastrointestinal platforms for the detection of gastroenteritis viruses

scientific article published on September 2017

Complex febrile seizures followed by complete recovery in an infant with high-titer 2009 pandemic influenza A (H1N1) virus infection

scientific article

Contribution of Beta-HPV Infection and UV Damage to Rapid-Onset Cutaneous Squamous Cell Carcinoma during BRAF-Inhibition Therapy

scientific article published on 27 February 2015

Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber ⬇️

scientific article published on January 15, 2002

Detection of Clostridioides difficile by Real-time PCR in Young Children Does Not Predict Disease

scientific article published on 01 June 2020

Detection of viruses in human adenoid tissues by use of multiplex PCR.

scientific article published on 30 December 2008

Determining the effectiveness of the pentavalent rotavirus vaccine against rotavirus hospitalizations and emergency department visits using two study designs ⬇️

scientific article published on April 12, 2013

Diagnostic performance of the BinaxNow Influenza A&B rapid antigen test in ED patients

scientific article published on 15 July 2012

Diarrheagenic Escherichia Coli and Acute Gastroenteritis in Children in Davidson County, Tennessee, United States: A Case-Control Study

scientific article published on 16 January 2018

Differences in the Nasopharyngeal Microbiome During Acute Respiratory Tract Infection With Human Rhinovirus and Respiratory Syncytial Virus in Infancy

scientific article

Direct and Indirect Effects of Rotavirus Vaccination Upon Childhood Hospitalizations in 3 US Counties, 2006–2009 ⬇️

scientific article published on June 23, 2011

Diversity and relationships of cocirculating modern human rotaviruses revealed using large-scale comparative genomics

scientific article

Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination

scientific article published on 03 December 2020

Effectiveness of pentavalent and monovalent rotavirus vaccines in concurrent use among US children <5 years of age, 2009-2011

scientific article

Enteropathogenic and enteroaggregative E. coli in stools of children with acute gastroenteritis in Davidson County, Tennessee

scientific article

Epidemiologic Association Between FUT2 Secretor Status and Severe Rotavirus Gastroenteritis in Children in the United States

scientific article published on 21 September 2015

Evidence for Household Transmission of Rotavirus in the United States, 2011-2016

article

Gene-specific inhibition of reovirus replication by RNA interference.

scientific article

Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis

scientific article

Genotype prevalence and risk factors for severe clinical adenovirus infection, United States 2004-2006. ⬇️

scientific article

Glucagon-like peptide-1 receptor signaling attenuates RSV-induced type 2 responses and immunopathology

scientific article published on 17 April 2018

High prevalence of Group B Streptococcus colonization among pregnant women in Amman, Jordan

scientific article published on 20 May 2019

Identification of Bacterial and Viral Codetections With Mycoplasma pneumoniae Using the TaqMan Array Card in Patients Hospitalized With Community-Acquired Pneumonia

scientific article published on 30 March 2016

Identification of functional domains in reovirus replication proteins muNS and mu2.

scientific article published on 28 January 2009

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.

scientific article published on 14 August 2017

Importance of neutralizing monoclonal antibodies targeting multiple antigenic sites on MERS-CoV Spike to avoid neutralization escape

scientific article published on 7 March 2018

Improving Influenza Testing and Treatment in Hospitalized Children

scientific article published on 14 August 2018

Interference Between Respiratory Syncytial Virus and Human Rhinovirus Infection in Infancy.

scientific article published on 24 March 2017

Intestinal Carriage of Third-Generation Cephalosporin-Resistant and Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in Healthy US Children.

scientific article published on 15 June 2017

Long-term Consistency in Rotavirus Vaccine Protection: RV5 and RV1 Vaccine Effectiveness in US Children, 2012-2013.

scientific article published on 8 October 2015

Middle East Respiratory Syndrome.

scientific article

Molecular Detection and Characterization of Mycoplasma pneumoniae Among Patients Hospitalized With Community-Acquired Pneumonia in the United States

scientific article

Molecular Evolution and Intraclade Recombination of Enterovirus D68 during the 2014 Outbreak in the United States

scientific article published on 9 December 2015

Molecular epidemiology of contemporary G2P[4] human rotaviruses cocirculating in a single U.S. community: footprints of a globally transitioning genotype

scientific article published on 15 January 2014

Multiple introductions and antigenic mismatch with vaccines may contribute to increased predominance of G12P[8] rotaviruses in the United States ⬇️

scientific article published on 10 December 2018

Nasopharyngeal Lactobacillus is Associated with Childhood Wheezing Illnesses Following Acute Respiratory Syncytial Virus Infection in Infancy

scientific article published on 9 January 2018

Nasopharyngeal Microbiome in Respiratory Syncytial Virus Resembles Profile Associated with Increased Childhood Asthma Risk

scientific article published on May 2016

Norovirus and medically attended gastroenteritis in U.S. children

scientific article

Objectives, design and enrollment results from the Infant Susceptibility to Pulmonary Infections and Asthma Following RSV Exposure Study (INSPIRE).

scientific article published on 30 April 2015

Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease

scientific article

Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina.

scientific article

Procalcitonin as an Early Marker of the Need for Invasive Respiratory or Vasopressor Support in Adults With Community-Acquired Pneumonia

scientific article published on 20 April 2016

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

scientific article published on 07 July 2020

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice

scientific article published on 28 April 2020

Reovirus Replication Protein μ2 Influences Cell Tropism by Promoting Particle Assembly within Viral Inclusions ⬇️

scientific article published on July 25, 2012

Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice

scientific article

Reovirus-mediated induction of ADAR1 (p150) minimally alters RNA editing patterns in discrete brain regions.

scientific article

Respiratory Viral Detection in Children and Adults: Comparing Asymptomatic Controls and Patients With Community-Acquired Pneumonia

scientific article

Respiratory virus shedding in a cohort of on-duty healthcare workers undergoing prospective surveillance

scientific article published on 08 February 2013

Rhinovirus Viremia in Patients Hospitalized With Community-Acquired Pneumonia

scientific article

Rotavirus Strain Trends During the Postlicensure Vaccine Era: United States, 2008-2013.

scientific article published on 14 June 2016

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

scientific article published on 11 June 2020

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness

scientific article published on 05 August 2020

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

scientific article published on 29 September 2020

Secondhand Smoke Exposure and Illness Severity among Children Hospitalized with Pneumonia

scientific article

Serology Enhances Molecular Diagnosis of Respiratory Virus Infections Other than Influenza in Children and Adults Hospitalized with Community-Acquired Pneumonia

scientific article published on 19 October 2016

Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes

scientific article

Simultaneous detection and high-throughput identification of a panel of RNA viruses causing respiratory tract infections

scientific article published on 16 May 2007

Small-Molecule Antiviral β-d--Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance

Staphylococcus aureus Community-acquired Pneumonia: Prevalence, Clinical Characteristics, and Outcomes

scientific article published on 8 May 2016

Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD

scientific article published on 01 September 2019

Temporal and Genotypic Associations of Sporadic Norovirus Gastroenteritis and Reported Norovirus Outbreaks in Middle Tennessee, 2012-2016

scientific article published on 13 November 2019

The Changing Landscape of Pediatric Viral Enteropathogens in the Post-Rotavirus Vaccine Era

scientific article published on 03 February 2020

The coronavirus proofreading exoribonuclease mediates extensive viral recombination

Time to clinical stability among children hospitalized with pneumonia

scientific article published on 28 April 2015

Use of intravenous zanamivir after development of oseltamivir resistance in a critically Ill immunosuppressed child infected with 2009 pandemic influenza A (H1N1) virus.

scientific article

Using Multiplex Molecular Testing to Determine the Etiology of Acute Gastroenteritis in Children

scientific article published on 18 June 2016

Viral Etiology of Acute Gastroenteritis in <2-Year-Old US Children in the Post-Rotavirus Vaccine Era

scientific article published on 01 November 2019

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