List of works - Irene Y Cheung

Activation of peripheral-blood granulocytes is strongly correlated with patient outcome after immunotherapy with anti-GD2 monoclonal antibody and granulocyte-macrophage colony-stimulating factor

scientific article published on 27 December 2011

Adoptive immunotherapy with haploidentical natural killer cells and Anti-GD2 monoclonal antibody m3F8 for resistant neuroblastoma: Results of a phase I study

scientific article published on 10 May 2018

Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody hu3F8

scientific article published on 7 April 2015

Analysis of GD2/GM2 synthase mRNA as a biomarker for small cell lung cancer

scientific article

Anti-GD2 antibody 3F8 and barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I study in patients with chemoresistant neuroblastoma

scientific article

Anti-idiotypic antibody as the surrogate antigen for cloning scFv and its fusion proteins

scientific article published on 01 December 2002

Anti-idiotypic antibody facilitates scFv chimeric immune receptor gene transduction and clonal expansion of human lymphocytes for tumor therapy

scientific article published on August 2003

Antitumor Efficacy of Anti-GD2 IgG1 Is Enhanced by Fc Glyco-Engineering

scientific article published on 16 May 2016

Association of age at diagnosis and genetic mutations in patients with neuroblastoma.

scientific article

B7H3-Directed Intraperitoneal Radioimmunotherapy With Radioiodinated Omburtamab for Desmoplastic Small Round Cell Tumor and Other Peritoneal Tumors: Results of a Phase I Study

scientific article published on 29 October 2020

Bone marrow minimal residual disease was an early response marker and a consistent independent predictor of survival after anti-GD2 immunotherapy

scientific article

Checkpoint kinase inhibitor synergizes with DNA‐damaging agents in G1 checkpoint‐defective neuroblastoma ⬇️

scientific article published on March 8, 2011

Cyclin D1, a novel molecular marker of minimal residual disease, in metastatic neuroblastoma

scientific article published on April 2007

Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis

scientific article

Early Molecular Response of Marrow Disease to Biologic Therapy Is Highly Prognostic in Neuroblastoma ⬇️

scientific article published on October 15, 2003

Early negative minimal residual disease in bone marrow after immunotherapy is less predictive of late or non‐marrow relapse among patients with high‐risk stage 4 neuroblastoma ⬇️

scientific article published on January 17, 2013

Exploiting gene expression profiling to identify novel minimal residual disease markers of neuroblastoma

scientific article

FCGR2APolymorphism Is Correlated With Clinical Outcome After Immunotherapy of Neuroblastoma With Anti-GD2 Antibody and Granulocyte Macrophage Colony-Stimulating Factor

article by Nai-Kong V. Cheung et al published 20 June 2006 in Journal of Clinical Oncology

High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy

scientific article published in April 2007

Human derived dimerization tag enhances tumor killing potency of a T-cell engaging bispecific antibody

scientific article published on 27 April 2015

Humanized 3F8 Anti-GD2 Monoclonal Antibody Dosing With Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Resistant Neuroblastoma: A Phase 1 Clinical Trial

scientific article published on 01 December 2018

Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo ⬇️

scientific article published on July 1, 2012

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

scientific article published on 24 November 2009

Key role for myeloid cells: phase II results of anti-G(D2) antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma

scientific article

Lack of survival advantage with autologous stem-cell transplantation in high-risk neuroblastoma consolidated by anti-GD2 immunotherapy and isotretinoin

scientific article published on 26 November 2015

MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas

scientific article published on 19 August 2011

MYCN-amplified stage 2/3 neuroblastoma: excellent survival in the era of anti-GD2 immunotherapy.

scientific article published on 24 August 2017

Measuring circulating neuroblastoma cells by quantitative reverse transcriptase-polymerase chain reaction analysis

scientific article published in November 2004

MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors

scientific article published on 07 July 2009

Murine anti-GD2 monoclonal antibody 3F8 combined with granulocyte-macrophage colony-stimulating factor and 13-cis-retinoic acid in high-risk patients with stage 4 neuroblastoma in first remission

scientific article

Novel markers of subclinical disease for Ewing family tumors from gene expression profiling

scientific article published on December 2007

Oncotargets GD2 and GD3 are highly expressed in sarcomas of children, adolescents, and young adults

scientific article published on 15 June 2016

Phase I trial of a bivalent gangliosides vaccine in combination with β-glucan for high-risk neuroblastoma in second or later remission

scientific article published on 11 February 2014

Phase I trial of anti-GD2 monoclonal antibody hu3F8 plus GM-CSF: Impact of body weight, immunogenicity and anti-GD2 response on pharmacokinetics and survival.

scientific article published on 31 July 2017

Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma

scientific article published on 17 March 2011

Prolonged progression-free survival after consolidating second or later remissions of neuroblastoma with Anti-GD2 immunotherapy and isotretinoin: a prospective Phase II study

scientific article published on 22 May 2015

Quantitation of GD2 synthase mRNA by real-time reverse transcriptase polymerase chain reaction: clinical utility in evaluating adjuvant therapy in neuroblastoma

scientific article published on 01 March 2003

Quantitation of GD2 synthase mRNA by real-time reverse transcription-polymerase chain reaction: utility in bone marrow purging of neuroblastoma by anti-GD2 antibody 3F8

scientific article published on 01 June 2002

Recurrent pre-existing and acquired DNA copy number alterations, including focal TERT gains, in neuroblastoma central nervous system metastases

scientific article published on 10 October 2013

Reply to L. Moreno et al.

scientific article published in February 2013

Sialyltransferase STX (ST8SiaII): a novel molecular marker of metastatic neuroblastoma

scientific article published on July 2006

Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma with Prior Disease Progression

scientific article published on 16 December 2020

List of works by Irene Y Cheung

Activation of peripheral-blood granulocytes is strongly correlated with patient outcome after immunotherapy with anti-GD2 monoclonal antibody and granulocyte-macrophage colony-stimulating factor

Adoptive immunotherapy with haploidentical natural killer cells and Anti-GD2 monoclonal antibody m3F8 for resistant neuroblastoma: Results of a phase I study

Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody hu3F8

Analysis of GD2/GM2 synthase mRNA as a biomarker for small cell lung cancer

Anti-GD2 antibody 3F8 and barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I study in patients with chemoresistant neuroblastoma

Anti-idiotypic antibody as the surrogate antigen for cloning scFv and its fusion proteins

Anti-idiotypic antibody facilitates scFv chimeric immune receptor gene transduction and clonal expansion of human lymphocytes for tumor therapy

Antitumor Efficacy of Anti-GD2 IgG1 Is Enhanced by Fc Glyco-Engineering

Association of age at diagnosis and genetic mutations in patients with neuroblastoma.

B7H3-Directed Intraperitoneal Radioimmunotherapy With Radioiodinated Omburtamab for Desmoplastic Small Round Cell Tumor and Other Peritoneal Tumors: Results of a Phase I Study

Bone marrow minimal residual disease was an early response marker and a consistent independent predictor of survival after anti-GD2 immunotherapy

Checkpoint kinase inhibitor synergizes with DNA‐damaging agents in G1 checkpoint‐defective neuroblastoma ⬇️

Cyclin D1, a novel molecular marker of minimal residual disease, in metastatic neuroblastoma

Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis

Early Molecular Response of Marrow Disease to Biologic Therapy Is Highly Prognostic in Neuroblastoma ⬇️

Early negative minimal residual disease in bone marrow after immunotherapy is less predictive of late or non‐marrow relapse among patients with high‐risk stage 4 neuroblastoma ⬇️

Exploiting gene expression profiling to identify novel minimal residual disease markers of neuroblastoma

FCGR2APolymorphism Is Correlated With Clinical Outcome After Immunotherapy of Neuroblastoma With Anti-GD2 Antibody and Granulocyte Macrophage Colony-Stimulating Factor

High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy

Human derived dimerization tag enhances tumor killing potency of a T-cell engaging bispecific antibody

Humanized 3F8 Anti-GD2 Monoclonal Antibody Dosing With Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Resistant Neuroblastoma: A Phase 1 Clinical Trial

Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo ⬇️

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

Key role for myeloid cells: phase II results of anti-G(D2) antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma

Lack of survival advantage with autologous stem-cell transplantation in high-risk neuroblastoma consolidated by anti-GD2 immunotherapy and isotretinoin

MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas

MYCN-amplified stage 2/3 neuroblastoma: excellent survival in the era of anti-GD2 immunotherapy.

Measuring circulating neuroblastoma cells by quantitative reverse transcriptase-polymerase chain reaction analysis

MicroRNA miR-29 modulates expression of immunoinhibitory molecule B7-H3: potential implications for immune based therapy of human solid tumors

Murine anti-GD2 monoclonal antibody 3F8 combined with granulocyte-macrophage colony-stimulating factor and 13-cis-retinoic acid in high-risk patients with stage 4 neuroblastoma in first remission

Novel markers of subclinical disease for Ewing family tumors from gene expression profiling

Oncotargets GD2 and GD3 are highly expressed in sarcomas of children, adolescents, and young adults

Phase I trial of a bivalent gangliosides vaccine in combination with β-glucan for high-risk neuroblastoma in second or later remission

Phase I trial of anti-GD2 monoclonal antibody hu3F8 plus GM-CSF: Impact of body weight, immunogenicity and anti-GD2 response on pharmacokinetics and survival.

Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma

Prolonged progression-free survival after consolidating second or later remissions of neuroblastoma with Anti-GD2 immunotherapy and isotretinoin: a prospective Phase II study

Quantitation of GD2 synthase mRNA by real-time reverse transcriptase polymerase chain reaction: clinical utility in evaluating adjuvant therapy in neuroblastoma

Quantitation of GD2 synthase mRNA by real-time reverse transcription-polymerase chain reaction: utility in bone marrow purging of neuroblastoma by anti-GD2 antibody 3F8

Recurrent pre-existing and acquired DNA copy number alterations, including focal TERT gains, in neuroblastoma central nervous system metastases

Reply to L. Moreno et al.

Sialyltransferase STX (ST8SiaII): a novel molecular marker of metastatic neuroblastoma

Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma with Prior Disease Progression

Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma