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List of works by Christine Falk

A positive feedback loop between IL-1β, LPS and NEU1 may promote atherosclerosis by enhancing a pro-inflammatory state in monocytes and macrophages

scientific article published on 22 January 2018

A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions.

scientific article

Ablation of proximal tubular suppressor of cytokine signaling 3 enhances tubular cell cycling and modifies macrophage phenotype during acute kidney injury.

scientific article published on 8 January 2014

Activation of p38 mitogen-activated protein kinase drives dendritic cells to become tolerogenic in ret transgenic mice spontaneously developing melanoma

scientific article published on 23 June 2009

Allogeneic MHC class I ligands and their role in positive and negative regulation of human cytotoxic effector cells

scientific article

Alloresponses of Mixed Lymphocyte Hepatocyte Culture to Immunosuppressive Drugs as an In-Vitro Model of Hepatocyte Transplantation

scientific article published on 13 August 2019

Angiogenic and growth factors in gastric cancer

scientific article published on 26 November 2014

Annexin A1 on the surface of early apoptotic cells suppresses CD8+ T cell immunity

scientific article

Anti-HDV IgM as a marker of disease activity in hepatitis delta

scientific article

Application of paclitaxel in low non-cytotoxic doses supports vaccination with melanoma antigens in normal mice

scientific article published on 27 March 2012

Association of angiogenic factors with prognosis in esophageal cancer

scientific article

Autoimmune hepatitis in a murine autoimmune polyendocrine syndrome type 1 model is directed against multiple autoantigens

scientific article published on 24 February 2015

Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery

scientific article

Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery

BRaf and MEK inhibitors differentially regulate cell fate and microenvironment in human hepatocellular carcinoma.

scientific article published on 26 February 2014

Back signaling of HLA class I molecules and T/NK cell receptor ligands in epithelial cells reflects the rejection-specific microenvironment in renal allograft biopsies

scientific article published on 28 May 2019

Baseline IL-2 and the AIH score can predict the response to standard therapy in paediatric autoimmune hepatitis

scientific article published on 11 January 2018

Biohybrid cochlear implants in human neurosensory restoration.

scientific article

Blood cytokine expression correlates with early multi-organ damage in a mouse model of moderate hypothermia with circulatory arrest using cardiopulmonary bypass

scientific article published in PLoS ONE

Blood vessel control of macrophage maturation promotes arteriogenesis in ischemia

scientific article published on 16 October 2017

CCR5 status and metastatic progression in colorectal cancer

scientific article published on 13 July 2019

CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivity

scientific article published on 31 May 2013

CD4 T Cell Dependent Colitis Exacerbation Following Re-Exposure of Mycobacterium avium ssp. paratuberculosis

scientific article published on 16 March 2017

CD40 Signaling Drives Potent Cellular Immune Responses in Heterologous Cancer Vaccinations.

scientific article published on 15 February 2017

CRELD1 modulates homeostasis of the immune system in mice and humans

scientific article published on 09 November 2020

Case Report: Daratumumab in a Patient With Severe Refractory Anti-NMDA Receptor Encephalitis

scientific article published on 22 December 2020

Cell-based vaccines for renal cell carcinoma: genetically-engineered tumor cells and monocyte-derived dendritic cells.

scientific article

Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.

scientific article published in December 2017

Cellular and molecular analyses of major histocompatibility complex (MHC) restricted and non-MHC-restricted effector cells recognizing renal cell carcinomas: problems and perspectives for immunotherapy ⬇️

scientific article published on June 1, 1997

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

scientific article

Combined high-throughput library screening and next generation RNA sequencing uncover microRNAs controlling human cardiac fibroblast biology

scientific article published on 27 October 2020

Commensal and pathogenic biofilms differently modulate peri-implant oral mucosa in an organotypic model

scientific article published on 17 July 2019

Correlation of molecular human leukocyte antigen typing and outcome in high-risk melanoma patients receiving adjuvant interferon.

scientific article

Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanoma

scientific article published on 6 December 2012

Cytokine Selection of MSC Clones with Different Functionality

scientific article published on 11 July 2019

Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma

scientific article published on February 2006

Data-derived modeling characterizes plasticity of MAPK signaling in melanoma

scientific article (publication date: September 2014)

Defining the Inflammatory Microenvironment in the Human Cochlea by Perilymph Analysis: Toward Liquid Biopsy of the Cochlea

scientific article published on 25 June 2019

Differential effects of Belatacept on virus-specific memory versus de novo allo-specific T cell responses of kidney transplant recipients and healthy donors

scientific article published on 21 April 2020

Distinct systemic cytokine networks in symptomatic and asymptomatic carotid stenosis

scientific article published on 15 December 2020

Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells.

scientific article published in October 2009

Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference

scientific article published on 17 March 2017

Early host-microbe interaction in a peri-implant oral mucosa-biofilm model

scientific article published on 23 April 2020

Effect of everolimus-based drug regimens on CMV-specific T-cell functionality after renal transplantation: 12-month ATHENA subcohort-study results

scientific article published on 11 December 2020

Effect of extracorporeal cytokine removal on vascular barrier function in a septic shock patient

scientific article published on 21 January 2017

Effects of personalized endurance training on cellular age and vascular function in middle-aged sedentary women

scientific article published on 13 May 2019

Efficient generation of gene-modified human natural killer cells via alpharetroviral vectors

scientific article published on 25 August 2015

Endogenous Deoxyribonuclease Activity and Cell-Free Deoxyribonucleic Acid in Acute Ischemic Stroke: A Cohort Study

scientific article published in 2022

Endothelial vulnerability and endothelial damage are associated with risk of graft-versus-host disease and response to steroid treatment

scientific article published on 03 October 2012

Engineered Salmonella enterica serovar Typhimurium overcomes limitations of anti-bacterial immunity in bacteria-mediated tumor therapy

scientific article published on 16 October 2017

Equally interchangeable? - How sex and gender affect transplantation

scientific article published on 04 February 2019

Experimental colitis is exacerbated by concomitant infection with Mycobacterium avium ssp. paratuberculosis.

scientific article published in November 2014

Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer

scientific article

Extracellular vesicles from human multipotent stromal cells protect against hearing loss after noise trauma in vivo

scientific article published on 01 December 2020

Extracorporeal cytokine removal in severe CAR-T cell associated cytokine release syndrome

scientific article published on 19 February 2020

Functional Pulmonary Magnetic Resonance Imaging for Detection of Ischemic Injury in a Porcine Ex-Vivo Lung Perfusion System Prior to Transplantation

scientific article published on 19 June 2018

Genetic evolution of T-cell resistance in the course of melanoma progression

scientific article published on 7 October 2014

Genetic predisposition and environmental danger signals initiate chronic autoimmune hepatitis driven by CD4+ T cells

scientific article published in July 2013

Guidelines for the use of flow cytometry and cell sorting in immunological studies

scientific article published on October 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

scientific article published on 01 October 2019

HSP70 enhances immunosuppressive function of CD4(+)CD25(+)FoxP3(+) T regulatory cells and cytotoxicity in CD4(+)CD25(-) T cells

scientific article

Harnessing innate and adaptive immunity for adoptive cell therapy of renal cell carcinoma

scientific article published on 07 March 2009

Hepatocyte growth factor levels in livers and serum at Kasai-portoenterostomy are not predictive of clinical outcome in infants with biliary atresia

scientific article published on 01 April 2019

Hepatocyte-induced CD4+ T cell alloresponse is associated with major histocompatibility complex class II up-regulation on hepatocytes and suppressible by regulatory T cells

scientific article published on 24 January 2018

High pre-transplant serum nitrate levels predict risk of acute steroid-refractory graft-versus-host disease in the absence of statin therapy.

scientific article published on 18 October 2013

Human NK cell education by inhibitory receptors for MHC class I.

scientific article published on 10 August 2006

Human regulatory T cells of G-CSF mobilized allogeneic stem cell donors qualify for clinical application

scientific article

Human regulatory T cells rapidly suppress T cell receptor-induced Ca(2+), NF-κB, and NFAT signaling in conventional T cells.

scientific article

Hyperferritinemia and hypergammaglobulinemia predict the treatment response to standard therapy in autoimmune hepatitis

scientific article

IFN-γ activated JAK1 shifts CD40-induced cytokine profiles in human antigen-presenting cells toward high IL-12p70 and low IL-10 production.

scientific article

Immune Status in Children Before Liver Transplantation-A Cross-Sectional Analysis Within the ChilsSFree Multicentre Cohort Study

scientific article published on 25 January 2019

Immune cells participate in the oncosuppressive activity of parvovirus H-1PV and are activated as a result of their abortive infection with this agent.

scientific article published on 15 December 2010

Immune monitoring after pediatric liver transplantation - the prospective ChilSFree cohort study.

scientific article

Immunological aspects of liver cell transplantation

scientific article

Impact of immunosuppressive therapy on brain derived cytokines after liver transplantation

scientific article published on 24 October 2019

Impairment of Wound Healing in Patients With Type 2 Diabetes Mellitus Influences Circulating MicroRNA Patterns via Inflammatory Cytokines

scientific article published on 26 March 2015

In Vitro Effects of Streptococcus oralis Biofilm on Peri-Implant Soft Tissue Cells

scientific article published on 15 May 2020

In peripartum cardiomyopathy Plasminogen Activator Inhibitor-1 is a potential new biomarker with controversial roles

scientific article published on 11 November 2019

Increased frequency of CD4+ CD25high CD127low T cells early after lung transplant is associated with improved graft survival - a retrospective study

scientific article published on 06 January 2020

Inducing Differentiation of Premalignant Hepatic Cells as a Novel Therapeutic Strategy in Hepatocarcinoma

scientific article published on 3 August 2016

Interferon-Mediated Cytokine Induction Determines Sustained Virus Control in Chronic Hepatitis C Virus Infection

scientific article published on 26 October 2015

Interferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis.

scientific article published on 25 September 2015

Intrahepatic regulatory T cells in autoimmune hepatitis are associated with treatment response and depleted with current therapies.

scientific article published on 2 June 2014

Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection

scientific article published on 13 January 2022

JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter

scientific article

Knock-out iPSCs for disease and therapy modeling of IL-10 associated primary immunodeficiencies

scientific article published on 06 October 2020

Long-term follow-up in peripartum cardiomyopathy patients with contemporary treatment: low mortality, high cardiac recovery, but significant cardiovascular co-morbidities

scientific article published on 13 November 2019

Long-term outcome and necessity of liver transplantation in infants with biliary atresia are independent of cytokine milieu in native liver and serum

scientific article published on 06 October 2018

MAIT cells are enriched and highly functional in ascites of patients with decompensated liver cirrhosis

scientific article published on 03 February 2020

Membrane receptors are not required to deliver granzyme B during killer cell attack

scientific article

Microglia isolated from patients with glioma gain antitumor activities on poly (I:C) stimulation

scientific article published on 20 October 2011

Modulation of HCV reinfection after orthotopic liver transplantation by fibroblast growth factor-2 and other non-interferon mediators

scientific article published on 23 March 2015

NK Cells of Kidney Transplant Recipients Display an Activated Phenotype that Is Influenced by Immunosuppression and Pathological Staging

scientific article published on 6 July 2015

NK cell activity during human cytomegalovirus infection is dominated by US2-11-mediated HLA class I down-regulation

scientific article published on September 2002

NK cells--from basic research to cancer therapy

scientific article published on 01 May 2007

NK-cell education is shaped by donor HLA genotype after unrelated allogeneic hematopoietic stem cell transplantation

scientific article published on 02 November 2010

Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum

scientific article

Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines

scientific article published on 01 February 2011

Natural killer resistance of a drug-resistant leukemia cell line, mediated by up-regulation of HLA class I expression.

scientific article published on May 2003

Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection

scientific article published in December 2009

Novel Cytokine Score and Cardiac Allograft Vasculopathy

scientific article published on 04 January 2019

Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy

scientific article

Plasma Acute Phase Proteins as Predictors of Chronic Lung Allograft Dysfunction in Lung Transplant Recipients

scientific article published on 30 November 2020

Preclinical Assessment of Suitable Natural Killer Cell Sources for Chimeric Antigen Receptor Natural Killer-Based "Off-the-Shelf" Acute Myeloid Leukemia Immunotherapies

scientific article published on 18 March 2019

Preemptive treatment of early donor-specific antibodies with IgA- and IgM-enriched intravenous human immunoglobulins in lung transplantation

scientific article published on 03 June 2018

Presence of Infected Gr-1CD11bCD11c Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in -Infected Mice

scientific article published on 16 October 2018

Pretransplant metabolic distress predicts relapse of acute myeloid leukemia after allogeneic stem cell transplantation

scientific article published on 01 May 2015

Prognostic significance of spontaneous antibody responses against tumor-associated antigens in malignant melanoma patients

article

Proliferative retinopathy predicts nephropathy: a 25-year follow-up study of type 1 diabetic patients ⬇️

scientific article published on June 18, 2011

Rapid suppression of cytokine transcription in human CD4+CD25 T cells by CD4+Foxp3+ regulatory T cells: independence of IL-2 consumption, TGF-beta, and various inhibitors of TCR signaling

scientific article

Rat renal transplant model for mixed acute humoral and cellular rejection: Weak correlation of serum cytokines/chemokines with intragraft changes

scientific article published on 20 August 2015

Recirculating IL-1R2+ Tregs fine-tune intrathymic Treg development under inflammatory conditions

scientific article published on 27 January 2020

Reduced humoral but stable cellular SARS-CoV-2-specific immunity in liver transplant recipients in the first year after COVID-19

scientific article published in 2022

Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis.

scientific article published in November 2005

Relevance of inducible nitric oxide synthase for immune control of Mycobacterium avium subspecies paratuberculosis infection in mice

scientific article published on 01 December 2020

Renal cell carcinoma-infiltrating natural killer cells express differential repertoires of activating and inhibitory receptors and are inhibited by specific HLA class I allotypes

scientific article published on 01 October 2003

Retaliation against tumor cells showing aberrant HLA expression using lymphokine activated killer-derived T cells

scientific article published on 01 January 2002

Role of soluble inflammatory mediators and different immune cell populations in early control of symptomatic acute hepatitis C virus infection

scientific article published on 01 February 2019

SEX MATTERS - COVID-19 IN KIDNEY TRANSPLANTATION

scientific article published on 04 January 2021

Second generation atypical antipsychotics olanzapine and aripiprazole reduce expression and secretion of inflammatory cytokines in human immune cells

scientific article published on 04 September 2018

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation

scientific article published on 27 August 2020

Silencing of HLA class I on primary human hepatocytes as a novel strategy for reduction in alloreactivity

scientific article published on 10 June 2019

Six-year experience with treatment of early donor-specific anti-HLA antibodies in pediatric lung transplantation using a human immunoglobulin-based protocol

scientific article published on 07 January 2020

Skin melanoma development in ret transgenic mice despite the depletion of CD25+Foxp3+ regulatory T cells in lymphoid organs

scientific article published on 19 October 2009

Soluble immune markers in the different phases of chronic hepatitis B virus infection

scientific article published on 01 October 2019

Staphylococcus aureus Alpha-Toxin Limits Type 1 While Fostering Type 3 Immune Responses

scientific article published on 07 August 2020

Steroid-refractory GVHD: T-cell attack within a vulnerable endothelial system

scientific article published on 02 June 2011

Superior antitumor in vitro responses of allogeneic matched sibling compared with autologous patient CD8+ T cells

scientific article published on December 2006

Suppression of human CD4+ T cell activation by 3,4-dimethoxycinnamonyl-anthranilic acid (tranilast) is mediated by CXCL9 and CXCL10

scientific article published on 14 June 2011

Systemic Virus Infections Differentially Modulate Cell Cycle State and Functionality of Long-Term Hematopoietic Stem Cells In Vivo.

scientific article published on June 2017

T Cells Going Innate

scientific article

T cell specific Cxcr5 deficiency prevents rheumatoid arthritis

scientific article

TCR-independent cytokine stimulation induces non-MHC-restricted T cell activity and is negatively regulated by HLA class I

scientific article published on 01 September 2006

The Antiviral Activity of the Cellular Glycoprotein LGALS3BP/90K is Species-Specific

scientific article

The CD6 scavenger receptor is differentially expressed on a CD56 natural killer cell subpopulation and contributes to natural killer-derived cytokine and chemokine secretion

scientific article published on 18 December 2010

The Peripheral NK Cell Repertoire after Kidney Transplantation is Modulated by Different Immunosuppressive Drugs

scientific article published on 28 February 2013

The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy

scientific article published on 04 July 2018

The global response to the COVID-19 pandemic: how have immunology societies contributed?

scientific article published on 10 September 2020

The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion

scientific article

The immunogenic potential of bacterial flagella for Salmonella-mediated tumor therapy

scientific article published on 21 November 2019

The intestinal micro-environment imprints stromal cells to promote efficient Treg induction in gut-draining lymph nodes ⬇️

scientific article published on August 14, 2013

Tolerance and chimerism

scientific article

Transplant arteriosclerosis in humanized mice reflects chronic lung allograft dysfunction and is controlled by regulatory T cells

scientific article published on 28 February 2019

Truncated HLA-G isoforms are retained in the endoplasmic reticulum and insufficiently provide HLA-E ligands

scientific article published in March 2004

Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.

scientific article

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

scientific article published on 01 April 2016

Upregulation of Major Histocompatibility Complex Class I on Liver Cells by Hepatitis C Virus Core Protein via p53 and TAP1 Impairs Natural Killer Cell Cytotoxicity

scientific article (publication date: August 2003)

Viral and Host Responses After Stopping Long-term Nucleos(t)ide Analogue Therapy in HBeAg-Negative Chronic Hepatitis B.

scientific article

miR-21 promotes fibrosis in an acute cardiac allograft transplantation model.

scientific article published on 9 February 2016

α-NAC-Specific Autoreactive CD8+ T Cells in Atopic Dermatitis Are of an Effector Memory Type and Secrete IL-4 and IFN-γ.

scientific article published on 9 March 2016

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