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List of works by Franz-Ulrich Hartl

70 Three-dimensional arrangements of ribosomes inside fast growingE. colicells

A balance of protein synthesis and proteasome-dependent degradation determines the maintenance of LTP.

scientific article published in October 2006

A comment on: 'The aromatic amino acid content of the bacterial chaperone protein groEL (cpn60): evidence for the presence of a single tryptophan', by N.C. Price, S.M. Kelly, S. Wood and A. auf der Mauer (1991) FEBS Lett. 292, 9-12.

scientific article

A molecular chaperone from a thermophilic archaebacterium is related to the eukaryotic protein t-complex polypeptide-1.

scientific article published in December 1991

A protein quality control pathway regulated by linear ubiquitination

scientific article published on 18 March 2019

A sensitive filter retention assay for the detection of PrP(Sc) and the screening of anti-prion compounds

scientific article

A stress sensor for the bacterial periplasm

scientific article

A zinc finger-like domain of the molecular chaperone DnaJ is involved in binding to denatured protein substrates.

scientific article published in January 1996

ATP-dependent protein refolding activity in reticulocyte lysate. Evidence for the participation of different chaperone components

scientific article published on September 1993

Aberrant protein interactions in amyloid disease

scientific article published on 15 May 2011

Action of the Hsp70 chaperone system observed with single proteins

scientific article

Active Cage Mechanism of Chaperonin-Assisted Protein Folding Demonstrated at Single-Molecule Level

scholarly article by Amit J. Gupta published in July 2014

Advancing cell biology through proteomics in space and time (PROSPECTS).

scientific article published on 6 February 2012

Alexander J. Varshavsky -- Felix Hoppe-Seylar lecturer 2000.

scientific article published in September 2000

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

scientific article published on January 2011

An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator

scientific article published on November 1999

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space

scientific article

Asymmetrical interaction of GroEL and GroES in the ATPase cycle of assisted protein folding.

scientific article

Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons

scientific article published on 7 June 2024

Autophagy preferentially degrades non-fibrillar polyQ aggregates

scientific article published on 9 August 2023

Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein

scientific article published on 17 January 2020

Binding of defined regions of a polypeptide to GroEL and its implications for chaperonin-mediated protein folding

scientific article published on 01 July 1995

Biogenesis and Metabolic Maintenance of Rubisco

scientific article published on 11 January 2017

Calpain inhibition is sufficient to suppress aggregation of polyglutamine-expanded ataxin-3.

scientific article published on 8 May 2007

Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD

scientific article published on 16 March 2020

Cellular Homeostasis and Aging

scientific article published on 6 April 2016

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

scientific article published on July 2004

Chaperone Machineries of Rubisco - The Most Abundant Enzyme

scientific article published on 26 May 2020

Chaperone-assisted protein folding.

scientific article

Chaperone-assisted protein folding: the path to discovery from a personal perspective ⬇️

scientific article published on October 11, 2011

Chaperones increase association of tau protein with microtubules

scientific article

Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers

scientific article published in September 2006

Chaperonin cofactors, Cpn10 and Cpn20, of green algae and plants function as hetero-oligomeric ring complexes

scientific article

Chaperonin-Assisted Protein Folding: Relative Population of Asymmetric and Symmetric GroEL:GroES Complexes

scholarly article by Shubhasis Haldar published in June 2015

Chaperonin-catalyzed rescue of kinetically trapped states in protein folding

scientific article

Chaperonin-mediated de novo generation of prion protein aggregates ⬇️

scientific article published on November 2, 2001

Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate ⬇️

scientific article published on July 4, 1991

Chaperonin-mediated protein folding: GroES binds to one end of the GroEL cylinder, which accommodates the protein substrate within its central cavity ⬇️

scientific article published on December 1, 1992

Characterization of a receptor for heat shock protein 70 on macrophages and monocytes

scientific article

Co-translational domain folding as the structural basis for the rapid de novo folding of firefly luciferase

scientific article published on July 1999

Coexistence of group I and group II chaperonins in the archaeon Methanosarcina mazei

scientific article

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system

scientific article

Compartmentation of protein folding in vivo: sequestration of non-native polypeptide by the chaperonin-GimC system

scientific article

Conformation of GroEL-bound alpha-lactalbumin probed by mass spectrometry.

scientific article

Conformational specificity of the chaperonin GroEL for the compact folding intermediates of alpha-lactalbumin

scientific article

Contribution of molecular chaperones to protein folding in the cytoplasm of prokaryotic and eukaryotic cells

scientific article

Control of folding and membrane translocation by binding of the chaperone DnaJ to nascent polypeptides

scientific article published on November 1993

Converging concepts of protein folding in vitro and in vivo

scientific article

Coupled chaperone action in folding and assembly of hexadecameric Rubisco

scientific article

Cryo-EM structure of the RbcL-RbcX complex

Crystal Structure of N-acetylneuraminate lyase from Mycoplasma synoviae, crystal form I

Crystal Structure of N-acetylneuraminate lyase from Mycoplasma synoviae, crystal form II

Crystal structure of CbbY (AT3G48420) from Arabidobsis thaliana

Crystal structure of CbbY (mutant D10N) from Rhodobacter sphaeroides in complex with Xylulose-(1,5)bisphosphate, crystal form I

Crystal structure of CbbY (mutant D10N) from Rhodobacter sphaeroides in complex with Xylulose-(1,5)bisphosphate, crystal form II

Crystal structure of CbbY from Rhodobacter sphaeroides in complex with phosphate

Crystal structure of Chaetomium thermophilum Skn7 with HSE DNA

Crystal structure of Chaetomium thermophilum Skn7 with SSRE DNA

article published in 2015

Crystal structure of RbcX from Anabaena CA

article published in 2007

Crystal structure of RbcX in complex with substrate

Crystal structure of RbcX point mutant Q29A

Crystal structure of RbcX point mutant Y17A/Y20L

Crystal structure of RbcX, crystal form I

Crystal structure of RbcX, crystal form II

Crystal structure of RbcX-IIa from Chlamydomonas reinhardtii

Crystal structure of RbcX-IIa from Chlamydomonas reinhardtii in complex with RbcL C-terminal tail

Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco

scientific article

Crystal structure of a chaperone-bound assembly intermediate of form I Rubisco

scholarly article published 20 July 2011

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

scientific article

Crystal structure of an archaeal actin homolog

scientific article published on 9 February 2006

Crystal structure of apo-CbbY from Rhodobacter sphaeroides

Crystal structure of human Hsf1 with HSE DNA

Crystal structure of human Hsf1 with Satellite III repeat DNA

article published in 2015

Crystal structure of selenomethionine-labeled RbcX

Crystal structure of the AAA+ protein CbbX, native structure

Crystal structure of the AAA+ protein CbbX, selenomethionine structure

Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK

scientific article

Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa. One gene codes for both the cytosolic and mitochondrial forms.

scientific article published in October 1988

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.

scientific article published on 3 December 2015

Cytosolic Protein Vms1 Links Ribosome Quality Control to Mitochondrial and Cellular Homeostasis

scientific article

De novo folding of GFP fusion proteins: high efficiency in eukaryotes but not in bacteria

scientific article

Degradation of potent Rubisco inhibitor by selective sugar phosphatase

scientific article

Detection and selective dissociation of intact ribosomes in a mass spectrometer

scientific article published on May 2000

Differential substrate specificity of group I and group II chaperonins in the archaeon Methanosarcina mazei

scientific article published on 15 October 2009

Directionality of Polypeptide Transfer in the Mitochondrial Pathway of Chaperone-Mediated Protein Folding ⬇️

scientific article published on 01 March 1998

Distinct binding sites for the ATPase and substrate-binding domain of human Hsp70 on the cell surface of antigen presenting cells

scientific article

DnaK functions as a central hub in the E. coli chaperone network

scientific article published on 8 March 2012

DnaK, DnaJ and GrpE form a cellular chaperone machinery capable of repairing heat-induced protein damage.

scientific article

Dual Function of Protein Confinement in Chaperonin-Assisted Protein Folding

scientific article published on 01 October 2001

Dual Role of a Rubisco Activase in Metabolic Repair and Carboxysome Organization

scientific article published on 16 May 2020

Efficient production of native actin upon translation in a bacterial lysate supplemented with the eukaryotic chaperonin TRiC.

scientific article

Energy requirements for unfolding and membrane translocation of precursor proteins during import into mitochondria

scientific article published on 01 September 1990

Erratum: Degradation of potent Rubisco inhibitor by selective sugar phosphatase

scholarly article published in Nature Plants

Essential role of the chaperonin folding compartment in vivo

scientific article

Essential role of the unusual DNA-binding motif of BAG-1 for inhibition of the glucocorticoid receptor

scientific article published on 12 December 2002

Failure of RQC machinery causes protein aggregation and proteotoxic stress

scientific article published on 29 February 2016

Firefly luciferase mutants as sensors of proteome stress ⬇️

scientific article published on September 4, 2011

Fluc‐EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease

scientific article published on 19 August 2021

Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT.

scientific article published on 28 November 2012

Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

scientific article published in Nature

Formation and quantification of protein complexes between peroxisomal alcohol oxidase and GroEL

scientific article published on June 22, 1992

Function in protein folding of TRiC, a cytosolic ring complex containing TCP-1 and structurally related subunits ⬇️

scientific article published on December 1, 1992

Function of trigger factor and DnaK in multidomain protein folding: increase in yield at the expense of folding speed

scientific article

Functional characterization of an archaeal GroEL/GroES chaperonin system: significance of substrate encapsulation

scientific article published on 23 October 2003

Functional interaction of heat shock protein GroEL with an RNase E-like activity in Escherichia coli

scientific article

Functional significance of symmetrical versus asymmetrical GroEL-GroES chaperonin complexes.

scientific article

Gel-like inclusions of C-terminal fragments of TDP-43 sequester and inhibit proteasomes in neurons

scientific article published on 16 March 2021

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

scientific article published in June 2001

Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons

scientific article published on 19 April 2022

GroEL Ring Separation and Exchange in the Chaperonin Reaction

scientific article published on 26 December 2017

GroEL/ES Chaperonin Modulates the Mechanism and Accelerates the Rate of TIM-Barrel Domain Folding

scientific article

Hats off to the tricorn protease

scientific article published on 01 November 1996

Heat shock proteins in protein folding and membrane translocation

scientific article published on January 1, 1991

High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins.

scientific article published on 15 December 2017

Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle ⬇️

scientific article published on November 17, 1995

How do polypeptides cross the mitochondrial membranes?

scientific article

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

scientific article

Hsp90: a specialized but essential protein-folding tool

scientific article

Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model

scientific article

Identification of in vivo substrates of the chaperonin GroEL

scientific article published in Nature

Identification of nascent chain interaction sites on trigger factor

scientific article published on 12 February 2007

Identification of nucleotide-binding regions in the chaperonin proteins GroEL and GroES.

scientific article

Import of proteins into mitochondria: a multi-step process

scientific article published on August 1988

Import of proteins into the various submitochondrial compartments

scientific article

Improved recombinant expression and purification of functional plant Rubisco

scientific article published on 14 March 2019

In Vivo Observation of Polypeptide Flux through the Bacterial Chaperonin System ⬇️

scientific article published on August 8, 1997

In situ architecture of neuronal α-Synuclein inclusions

scientific article published on 14 April 2021

In situ architecture of neuronal α-Synuclein inclusions

scientific article published on 7 August 2020

In vitro evidence that hsp90 contains two independent chaperone sites ⬇️

scientific article published on November 24, 1997

In vivo analysis of the overlapping functions of DnaK and trigger factor

scientific article

In vivo aspects of protein folding and quality control

scientific article published on July 2016

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

scientific article

Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70

scientific article

Inhibition of GR-mediated transcription by p23 requires interaction with Hsp90.

scientific article published on February 2004

Interplay of Acetyltransferase EP300 and the Proteasome System in Regulating Heat Shock Transcription Factor 1

article by Swasti Raychaudhuri et al published February 2014 in Cell

L25 functions as a conserved ribosomal docking site shared by nascent chain-associated complex and signal-recognition particle

scientific article

Ligand discrimination by TPR domains. Relevance and selectivity of EEVD-recognition in Hsp70 x Hop x Hsp90 complexes

scientific article

Lord of the rings: GroES structure

scientific article published on 01 January 1996

MODEL OF HEXAMERIC AAA DOMAIN ARRANGEMENT OF GREEN-TYPE RUBISCO ACTIVASE FROM TOBACCO.

Mass spectrometry of ribosomes and ribosomal subunits ⬇️

scientific article published on June 23, 1998

Mechanism of Enzyme Repair by the AAA+ Chaperone Rubisco Activase

scientific article published on 20 July 2017

Mechanism of chaperonin action: GroES binding and release can drive GroEL-mediated protein folding in the absence of ATP hydrolysis.

scientific article published in November 1996

Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria

scientific article

Mitochondrial precursor proteins are imported through a hydrophilic membrane environment

scientific article published on 01 December 1987

Mitochondrial protein import

scientific article published on 01 January 1989

Mitochondrial protein import: identification of processing peptidase and of PEP, a processing enhancing protein

scientific article published in June 1988

Mitochondrial stress signaling: a pathway unfolds

scientific article published on 18 December 2007

Molecular and structural architecture of polyQ aggregates in yeast

scientific article published on 26 March 2018

Molecular chaperone functions in protein folding and proteostasis

scientific article

Molecular chaperone functions of heat-shock proteins

scientific article published on January 1993

Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70

scientific article

Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

scientific article

Molecular chaperones in cellular protein folding

scientific article (publication date: 13 June 1996)

Molecular chaperones in cellular protein folding

scientific article published on February 1995

Molecular chaperones in cellular protein folding

scientific article published on September 1994

Molecular chaperones in protein folding and proteostasis ⬇️

scientific article (publication date: 20 July 2011)

Molecular chaperones in protein folding: the art of avoiding sticky situations

scientific article published on January 1994

Molecular chaperones in the cytosol: from nascent chain to folded protein

scientific article (publication date: 8 March 2002)

Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s

scientific article

Molecular recognition and self-assembly special feature: Self-assembled biomimetic [2Fe2S]-hydrogenase-based photocatalyst for molecular hydrogen evolution

scholarly article

Monitoring Protein Conformation along the Pathway of Chaperonin-Assisted Folding

More than folding: localized functions of cytosolic chaperones ⬇️

scientific article (publication date: October 2003)

MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin

scientific article published on December 1999

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G 4 C 2 RNA in a cellular model

scientific article published on 16 September 2020

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model

scientific article published on 23 June 2021

N-terminal polyglutamine-containing fragments inhibit androgen receptor transactivation function

scientific article

Negative stain EM Map of the AAA protein CbbX, a red-type Rubisco activase from R. sphaeroides

Novel proteostasis reporter mouse reveals different effects of cytoplasmic and nuclear aggregates on protein quality control in neurons

scientific article published on 10 November 2020

Nuclear magnetic resonance solution structure of the human Hsp40 (HDJ-1) J-domain

scientific article

Observation of the noncovalent assembly and disassembly pathways of the chaperone complex MtGimC by mass spectrometry

scientific article published in December 2000

On the Role of Symmetrical and Asymmetrical Chaperonin Complexes in Assisted Protein Folding

scholarly article by M. K. Hayer-Hartl published in January 1999

Opposing effects of folding and assembly chaperones on evolvability of Rubisco

scientific article

Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome

scientific article

Paper of the Year 2001: Award to Peter Hacke

scientific article published in October 2002

Paper of the Year 2002: Award to Cordelia Schiene-Fischer

scientific article published in September 2003

Paper of the year 2004: award to Yin Wang and Iris Lorenzi

scientific article published in September 2005

Pathways of cellular proteostasis in aging and disease

scientific article published on 10 November 2017

Pathways of chaperone-mediated protein folding in the cytosol

scientific article (publication date: October 2004)

Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

scientific article published on December 1996

Physicochemical determinants of chaperone requirements

scientific article

Plant RuBisCo assembly in E. coli with five chloroplast chaperones including BSD2.

scientific article published in December 2017

PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone

scientific article

Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23.

scientific article

Polypeptides traverse the mitochondrial envelope in an extended state

scientific article published on 01 November 1990

Post-translational protein import and folding

scientific article published on August 1994

Prevention of protein denaturation under heat stress by the chaperonin Hsp60

scientific article published on November 6, 1992

Principles of chaperone-assisted protein folding: differences between in vitro and in vivo mechanisms

scientific article

Principles of protein folding in the cellular environment

scientific article

Prokaryotic secretion: a signal recognition particle in Escherichia coli?

scientific article

Protein Misfolding Diseases

scientific article published on 24 April 2017

Protein abundance profiling of the Escherichia coli cytosol

scientific article

Protein folding in the cell: competing models of chaperonin function.

scientific article published on January 1996

Protein folding in the cell: molecular chaperones pave the way.

scientific article

Protein folding in the cell: the role of molecular chaperones Hsp70 and Hsp60

scientific article published on January 1, 1992

Protein folding in the central cavity of the GroEL-GroES chaperonin complex

scientific article

Protein folding in the cytoplasm and the heat shock response

scientific article

Protein folding in the cytosol: chaperonin-dependent and -independent mechanisms ⬇️

scientific article published on February 1, 1998

Protein folding. Secrets of a double-doughnut.

scientific article

Protein folding: versatility of the cytosolic chaperonin TRiC/CCT.

scientific article

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

scientific article

Protein sorting to mitochondria: evolutionary conservations of folding and assembly

scientific article published on February 1990

Protein synthesis upon acute nutrient restriction relies on proteasome function

scientific article published on December 2005

Protein-catalysed protein folding.

scientific article

Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3.

scientific article published on 11 January 2006

Proteome-wide Analysis of Chaperonin-Dependent Protein Folding in Escherichia coli

article

Proteostasis impairment in protein-misfolding and -aggregation diseases

scientific article

Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response

scientific article

Real-time observation of trigger factor function on translating ribosomes

scientific article

Recombination of protein domains facilitated by co-translational folding in eukaryotes ⬇️

scientific article published on July 24, 1997

Regulation of the heat-shock protein 70 reaction cycle by the mammalian DnaJ homolog, Hsp40.

scientific article

Remarkably stable radical anions derived from clusters [HOs3(CO)9(L)], L=ortho-metallated α-diimine: a spectro-electrochemical study and theoretical rationalization

Resolving chaperone-assisted protein folding on the ribosome at the peptide level

scientific article published on 10 July 2024

Roger D. Kornberg Felix Hoppe-Seyler Lecturer 2001

scientific article (publication date: 28 January 2001)

Role of auxiliary proteins in Rubisco biogenesis and function

scientific article published on 2 June 2015

Role of small subunit in mediating assembly of red-type form I Rubisco

scientific article

Role of the chaperonin cofactor Hsp10 in protein folding and sorting in yeast mitochondria

scientific article

Role of the myosin assembly protein UNC-45 as a molecular chaperone for myosin

scientific article published on January 2002

Roles of molecular chaperones in cytoplasmic protein folding

scientific article

Roles of molecular chaperones in protein misfolding diseases

scientific article published on February 2004

Rubisco Activases: AAA+ Chaperones Adapted to Enzyme Repair

scientific article

Scaffolding protein CcmM directs multiprotein phase separation in β-carboxysome biogenesis

scientific article published on 10 November 2021

Significant hydrogen exchange protection in GroEL-bound DHFR is maintained during iterative rounds of substrate cycling

scientific article

Sis1 potentiates the stress response to protein aggregation and elevated temperature

scientific article published on 08 December 2020

Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors

scientific article published on 25 August 2016

Soluble forms of polyQ-expanded huntingtin rather than large aggregates cause endoplasmic reticulum stress

scientific article published on January 2013

Sorting pathways of mitochondrial inner membrane proteins

scientific article published on September 1990

Specific Binding of Tetratricopeptide Repeat Proteins to the C-terminal 12-kDa Domain of hsp90 ⬇️

scientific article published on July 17, 1998

Stress proteins and mitochondrial protein import

scientific article published on October 1990

Structural Analysis of the Rubisco-Assembly Chaperone RbcX-II from Chlamydomonas reinhardtii

scientific article published on 25 August 2015

Structural Probing of a Protein Phosphatase 2A Network by Chemical Cross-Linking and Mass Spectrometry

scientific article

Structural basis for the cooperation of Hsp70 and Hsp110 chaperones in protein folding

scientific article

Structural features of the GroEL-GroES nano-cage required for rapid folding of encapsulated protein

scientific article

Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle ⬇️

scientific article published on June 30, 2013

Structure and function of RbcX, an assembly chaperone for hexadecameric Rubisco

scientific article

Structure and function of the AAA+ protein CbbX, a red-type Rubisco activase

scientific article

Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form I

Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form II

Structure of Chaetomium thermophilum Skn7 coiled-coil domain, crystal form III

Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine

scientific article

Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors

scientific article

Structure of green-type Rubisco activase from tobacco

scientific article

Structure of green-type Rubisco activase from tobacco

Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ

scientific article

Structure of human heat-shock transcription factor 1 in complex with DNA

scientific article

Structure of the molecular chaperone prefoldin: unique interaction of multiple coiled coil tentacles with unfolded proteins

scientific article

Successive action of DnaK, DnaJ and GroEL along the pathway of chaperone-mediated protein folding

scientific article published on April 23, 1992

Successive translocation into and out of the mitochondrial matrix: targeting of proteins to the intermembrane space by a bipartite signal peptide

scientific article published on 01 December 1987

Susan Lee Lindquist (1949-2016)-pioneer in the study of cellular protein folding and disease

scientific article

Synergistic inhibition of the glucocorticoid receptor by radicicol and benzoquinone ansamycins

scientific article

Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets

scientific article

TRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes

scientific article published on October 2003

TRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes

scientific article published on January 2008

Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast

scientific journal article

The ATP hydrolysis-dependent reaction cycle of the Escherichia coli Hsp70 system DnaK, DnaJ, and GrpE

scientific article (publication date: 25 October 1994)

The C-terminal domain of Rubisco Accumulation Factor 1 from Arabidopsis thaliana, crystal form I

The C-terminal domain of Rubisco Accumulation Factor 1 from Arabidopsis thaliana, crystal form II

The GroEL-GroES Chaperonin Machine: A Nano-Cage for Protein Folding

scientific article published on 03 September 2015

The N-terminal domain of Rubisco Accumulation Factor 1 from Arabidopsis thaliana

The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane

scientific article

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication

scientific article published on 25 March 2011

The chaperone Clusterin in neurodegeneration−friend or foe?

scientific article published on 6 May 2022

The effect of macromolecular crowding on chaperonin-mediated protein folding

scientific article

The enzymology of protein translocation across the Escherichia coli plasma membrane

scientific article published on January 1991

The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model

scientific article published on 11 August 2021

The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model

scientific article published on 16 July 2021

The first chaperonin

scientific article

The formation, function and regulation of amyloids: insights from structural biology

scientific article published on 30 May 2016

The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation

scientific article (publication date: October 2003)

The mitochondrial chaperonin hsp60 is required for its own assembly

scientific article

The molecular architecture of the eukaryotic chaperonin TRiC/CCT

scientific article

The native 3D organization of bacterial polysomes

scientific article

The nucleolus functions as a phase-separated protein quality control compartment

scientific article

The oligomeric structure of GroEL/GroES is required for biologically significant chaperonin function in protein folding

article

The processing peptidase of yeast mitochondria: the two co-operating components MPP and PEP are structurally related.

scientific article

The proteostasis network and its decline in ageing

scientific article published on 01 July 2019

The reaction cycle of GroEL and GroES in chaperonin-assisted protein folding.

scientific article

The role of molecular chaperones in human misfolding diseases

scientific article published on 23 April 2009

The role of molecular chaperones in protein folding

scientific article

The thermosome of Thermoplasma acidophilum and its relationship to the eukaryotic chaperonin TRiC.

scientific article published in February 1995

The three-dimensional organization of polyribosomes in intact human cells

scientific article

Topology of the morphological domains of the chaperonin GroEL visualized by immuno-electron microscopy

scientific article published on 01 September 1994

Translocation arrest by reversible folding of a precursor protein imported into mitochondria. A means to quantitate translocation contact sites

scientific article published on October 1989

Translocation intermediates on the import pathway of proteins into mitochondria

scientific article published on 01 February 1987

Transport into mitochondria and intramitochondrial sorting of the Fe/S protein of ubiquinol-cytochrome c reductase

scientific article published on 01 December 1986

Trigger factor lacking the PPIase domain can enhance the folding of eukaryotic multi-domain proteins in Escherichia coli

scientific article published on 24 July 2010

Two related genes encoding extremely hydrophobic proteins suppress a lethal mutation in the yeast mitochondrial processing enhancing protein ⬇️

scientific article published on December 5, 1992

Unfolding the chaperone story

scientific article published in November 2017

Versatility of trigger factor interactions with ribosome-nascent chain complexes

scientific article published on July 2010

Visualizing chaperonin function in situ by cryo-electron tomography

scientific article published on 21 August 2024

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

scientific article

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

scientific article

Wolfgang Baumeister--Felix Hoppe-Seyler Lecturer 2004.

scientific article published in October 2004

ΔμH+ and ATP function at different steps of the catalytic cycle of preprotein translocase ⬇️

scientific article published on March 8, 1991

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