Search filters

List of works by Inhee Mook-Jung

(18)F-Labeled benzylideneaniline derivatives as new ligands for beta-amyloid plaque imaging in Alzheimer's disease

scientific article published in February 2009

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling ⬇️

scientific article published on June 27, 2012

A Breakdown in Metabolic Reprogramming Causes Microglia Dysfunction in Alzheimer's Disease

scientific article published on 27 June 2019

A phosphomimetic mutant TDP-43 (S409/410E) induces Drosha instability and cytotoxicity in Neuro 2A cells

scientific article

A quadrupolar two-photon fluorescent probe for in vivo imaging of amyloid-β plaques

scientific article published on 07 April 2016

A relationship between Alzheimer's disease and type 2 diabetes mellitus through the measurement of serum amyloid-beta autoantibodies

scientific article published in January 2010

Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions

scientific article published on 29 August 2012

Accumulation of phosphorylated beta-catenin enhances ROS-induced cell death in presenilin-deficient cells

scientific article

Acetylation changes tau interactome to degrade tau in Alzheimer's disease animal and organoid models

scientific article published on 25 November 2019

Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation

scientific article

Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes

scientific article published on March 2014

Altered APP Processing in Insulin-Resistant Conditions Is Mediated by Autophagosome Accumulation via the Inhibition of Mammalian Target of Rapamycin Pathway ⬇️

scientific article published on July 24, 2012

Altered free amino acid levels in brain cortex tissues of mice with Alzheimer's disease as their N(O,S)-ethoxycarbonyl/tert-butyldimethylsilyl derivatives

scientific article

Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin.

scientific article

Aminostyrylbenzofuran derivatives as potent inhibitors for Abeta fibril formation

scientific article

Amyloid beta peptide directly inhibits PKC activation

scientific article published on June 2004

Amyloid beta regulates ER exit sites formation through O-GlcNAcylation triggered by disrupted calcium homeostasis

scientific article published on 03 September 2020

Amyloid beta-mediated epigenetic alteration of insulin-like growth factor binding protein 3 controls cell survival in Alzheimer's disease

scientific article

Amyloid peptide attenuates the proteasome activity in neuronal cells

scientific article published on 8 September 2005

Amyloid precursor protein processing is separately regulated by protein kinase C and tyrosine kinase in human astrocytes

scientific article

Amyloid β-induced elevation of O-GlcNAcylated c-Fos promotes neuronal cell death

scientific article published on 04 December 2018

Amyloid β-interacting partners in Alzheimer's disease: From accomplices to possible therapeutic targets

scientific article published on 22 December 2015

Annexin A1 restores Aβ1-42 -induced blood-brain barrier disruption through the inhibition of RhoA-ROCK signaling pathway

scientific article published on 16 September 2016

Astrocyte-Originated ATP Protects Aβ1-42-Induced Impairment of Synaptic Plasticity ⬇️

scientific article published on February 29, 2012

Autophagy-Mediated Secretory Pathway is Responsible for Both Normal and Pathological Tau in Neurons

scientific article published on 01 January 2019

Aβ-induced Ca(2+) influx regulates astrocytic BACE1 expression via calcineurin/NFAT4 signals

scientific article published on July 27, 2012

Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer's disease

scientific article

Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling ⬇️

scientific article published on November 1, 2011

BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis

scientific article published in April 2008

Bis-styrylpyridine and bis-styrylbenzene derivatives as inhibitors for Abeta fibril formation

scientific article published on 2 November 2006

Blood acetylcholinesterase level is a potential biomarker for the early detection of cerebral amyloid deposition in cognitively normal individuals

scientific article published on 08 September 2018

Both targeted mass spectrometry and flow sorting analysis methods detected the decreased serum apolipoprotein E level in Alzheimer's disease patients

scientific article published on 08 December 2013

Brain somatic mutations observed in Alzheimer's disease associated with aging and dysregulation of tau phosphorylation

scientific article published on 12 July 2019

Branched diacylglycerol-lactones as potent protein kinase C ligands and alpha-secretase activators

scientific article published on March 2006

Cell-based assay for β-secretase activity ⬇️

scientific article published on December 1, 2003

Chemically treated plasma Aβ is a potential blood-based biomarker for screening cerebral amyloid deposition

scientific article published on 22 March 2017

Close Correlation of Monoamine Oxidase Activity with Progress of Alzheimer's Disease in Mice, Observed by in Vivo Two-Photon Imaging

scientific article

Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons

scientific article

Contribution of presenilin/gamma-secretase to calsenilin-mediated apoptosis.

scientific article published in May 2003

Contributions of microglia to structural synaptic plasticity

scientific article

Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians

scientific article published on 8 July 2013

Correlation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease

scientific article

Cytosolic Extract of Human Adipose Stem Cells Reverses the Amyloid Beta-Induced Mitochondrial Apoptosis via P53/Foxo3a Pathway

scientific article

Cytosolic amyloid-beta peptide 42 escaping from degradation induces cell death

scientific article published on 4 April 2006

DMC (2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone) improves glucose tolerance as a potent AMPK activator.

scientific article published on 29 December 2015

Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer's disease

scientific article published on 15 November 2019

Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease.

scientific article

Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling

scientific article

Disruption of blood-brain barrier in Alzheimer disease pathogenesis

scientific article published on April 2013

Diverse molecular targets for therapeutic strategies in Alzheimer's disease

scientific article

ERK1/2 is an endogenous negative regulator of the gamma-secretase activity

scientific article published on 17 November 2005

Effect of conjugated linoleic acid, μ-calpain inhibitor, on pathogenesis of Alzheimer's disease ⬇️

scientific article published on December 14, 2012

Effect of ischemic neuronal insults on amyloid precursor protein processing

scientific article published on 21 June 2006

Effective screen for amyloid β aggregation inhibitor using amyloid β-conjugated gold nanoparticles ⬇️

scientific article published on December 15, 2010

Effects of Chronic Tinnitus on Metabolic and Structural Changes in Subjects With Mild Cognitive Impairment

scientific article published on 19 November 2020

Electroacupuncture Enhances Motor Recovery Performance with Brain-Derived Neurotrophic Factor Expression in Rats with Cerebral Infarction ⬇️

scientific article published on June 23, 2012

Furin is an endogenous regulator of alpha-secretase associated APP processing

scientific article published on 22 August 2006

Gami-Chunghyuldan ameliorates memory impairment and neurodegeneration induced by intrahippocampal Aβ 1-42 oligomer injection

scientific article published on 13 June 2011

Genetic associations of in vivo pathology influence Alzheimer's disease susceptibility

scientific article published on 19 November 2020

Ghrelin Ameliorates Cognitive Dysfunction and Neurodegeneration in Intrahippocampal Amyloid-β1-42 Oligomer-Injected Mice ⬇️

scientific article published on January 1, 2011

Global changes of phospholipids identified by MALDI imaging mass spectrometry in a mouse model of Alzheimer's disease

scientific article published on 4 November 2015

HDAC6 Inhibitor Blocks Amyloid Beta-Induced Impairment of Mitochondrial Transport in Hippocampal Neurons ⬇️

scientific article published on August 22, 2012

HDAC6 Inhibitors Rescued the Defective Axonal Mitochondrial Movement in Motor Neurons Derived from the Induced Pluripotent Stem Cells of Peripheral Neuropathy Patients with HSPB1 Mutation

scientific article

Harnessing Intramolecular Rotation To Enhance Two-photon Imaging of Aβ Plaques through Minimizing Background Fluorescence

scientific article published on 20 March 2019

Hearing loss as a risk factor for cognitive impairment and loss of synapses in the hippocampus

scientific article published on 02 July 2019

Human serum transthyretin levels correlate inversely with Alzheimer's disease

scientific article published on 01 January 2011

IFN-gamma-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT1 to BACE1 promoter in astrocytes

scientific article published on February 2007

Identification of autoantibody against beta-amyloid peptide in the serum of elderly

scientific article published in January 2009

Impaired Short-Term Plasticity in Mossy Fiber Synapses Caused by Mitochondrial Dysfunction of Dentate Granule Cells Is the Earliest Synaptic Deficit in a Mouse Model of Alzheimer's Disease ⬇️

scientific article published on April 25, 2012

Impaired hippocampal neurogenesis and its enhancement with ghrelin in 5XFAD mice

scientific article published on January 2014

Increased acetylation of Peroxiredoxin1 by HDAC6 inhibition leads to recovery of Aβ-induced impaired axonal transport

scientific article published on 28 February 2017

Induction of homosynaptic long-term depression in entorhinal cortex

scientific article published in November 2002

Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease

2012 scientific article

Induction of pro-apoptotic calsenilin/DREAM/KChIP3 in Alzheimer's disease and cultured neurons after amyloid-beta exposure

scientific article

Induction of pro-apoptotic calsenilin/DREAM/KChIP3 in Alzheimer's disease and cultured neurons after amyloid-β exposure

scientific article published in 2004

Inhibition of Cholesterol Biosynthesis Reduces γ-Secretase Activity and Amyloid-β Generation

scientific article published on 20 February 2016

Inhibition of glutaminyl cyclase ameliorates amyloid pathology in an animal model of Alzheimer's disease via the modulation of γ-secretase activity.

scientific article published on January 2015

Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease.

scientific article published on 10 March 2016

Intracellular Amyloid-β Accumulation in Calcium-Binding Protein-Deficient Neurons Leads to Amyloid-β Plaque Formation in Animal Model of Alzheimer's Disease ⬇️

scientific article published on January 1, 2012

Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice.

scientific article

Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice

scientific article published on 23 March 2018

Knock-down of protein L-isoaspartyl O-methyltransferase increases β-amyloid production by decreasing ADAM10 and ADAM17 levels

scientific article published on March 2011

Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease: Methodology and Baseline Sample Characteristics

scientific article published on 7 November 2017

LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase

scientific article

Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice

scientific article published in September 2003

Low Serum Phosphorus Correlates with Cerebral Aβ Deposition in Cognitively Impaired Subjects: Results from the KBASE Study

scientific article published on 6 November 2017

Metformin Facilitates Amyloid-β Generation by β- and γ-Secretases via Autophagy Activation

scientific article published on 26 February 2016

MicroRNA-124 slows down the progression of Huntington's disease by promoting neurogenesis in the striatum.

scientific article published on May 2015

Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model

scientific article published on 23 September 2016

Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model

scientific article

Mimicry of Central-Peripheral Immunity in Alzheimer's Disease and Discovery of Neurodegenerative Roles in Neutrophil

scientific article published on 25 September 2019

Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death ⬇️

scientific article published on April 13, 2012

Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer's Disease

scientific article published on 4 February 2016

Mitochondrial ATP synthase activity is impaired by suppressed O-GlcNAcylation in Alzheimer's disease.

scientific article published on 10 September 2015

Mitochondrial abnormalities related to the dysfunction of circulating endothelial colony-forming cells in moyamoya disease

scientific article

Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway

scientific article

Modulation of mitochondrial function by stem cell-derived cellular components.

scientific article published on 4 May 2014

Molecular and functional signatures in a novel Alzheimer's disease mouse model assessed by quantitative proteomics

scientific article published on 16 January 2018

Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity

scientific article published on June 2004

Neuroprotective effects of constituents of the oriental crude drugs, Rhodiola sacra, R. sachalinensis and Tokaku-joki-to, against beta-amyloid toxicity, oxidative stress and apoptosis ⬇️

scientific article published in August 2002

New Microglia on the Block

scientific article published on 01 April 2020

Nurr1 (NR4A2) regulates Alzheimer's disease-related pathogenesis and cognitive function in the 5XFAD mouse model

scientific article published on 04 December 2018

O-GlcNAcylation regulates endoplasmic reticulum exit sites through Sec31A modification in conventional secretory pathway

scientific article published on 17 April 2018

O-GlcNAcylation regulates hyperglycemia-induced GPX1 activation

scientific journal article

O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment

scientific article published on 11 April 2012

PRAK mediates Aβ-RAGE driven autophagy pathway

scientific article published on 6 January 2017

Performance of the QPLEX™ Alz plus assay, a novel multiplex kit for screening cerebral amyloid deposition

scientific article published on 06 January 2021

Peripheral inflammatory biomarkers in Alzheimer's disease: a brief review

scientific article published on 01 January 2020

Phosphokinase antibody arrays on dendron-coated surface.

scientific article

PiB-PET Imaging-Based Serum Proteome Profiles Predict Mild Cognitive Impairment and Alzheimer's Disease

scientific article published on 6 July 2016

Plasma tau/amyloid-β1-42 ratio predicts brain tau deposition and neurodegeneration in Alzheimer's disease

scientific article published on 01 March 2019

Profiling proteins related to amyloid deposited brain of Tg2576 mice

scientific article

Prognostic plasma protein panel for Aβ deposition in the brain in Alzheimer's disease

scientific article published on 09 October 2019

Protein-Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's Disease

scientific article

Quantitative proteomic analysis of the hippocampus in the 5XFAD mouse model at early stages of Alzheimer's disease pathology.

scientific article published on January 2013

RAGE: the beneficial and deleterious effects by diverse mechanisms of actions

scientific article published on 18 January 2011

RNA-Seq analysis of frontal cortex and cerebellum from 5XFAD mice at early stage of disease pathology

scientific article published on January 2012

Rac1 changes the substrate specificity of gamma-secretase between amyloid precursor protein and Notch1.

scientific article

Reduced serum level of antibodies against amyloid beta peptide is associated with aging in Tg2576 mice.

scientific article published on 27 July 2007

Regulation of autophagic proteolysis by the N-recognin SQSTM1/p62 of the N-end rule pathway

scientific article published on 20 December 2017

Retraction of "β-Amyloid and α-Synuclein Cooperate To Block SNARE-Dependent Vesicle Fusion".

scientific article published on 10 February 2017

Role for PKC-epsilon in neuronal death induced by oxidative stress

scientific article published on July 2004

SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease

scientific article

SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians

scientific article

Special issue on neurodegenerative diseases and their therapeutic approaches

scientific article published on 13 March 2015

Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR

scientific article published on 31 July 2018

Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway

scientific article published on 31 October 2015

Stepwise silver-staining-based immunosorbent assay for amyloid-beta autoantibody detection

scientific article published on 01 August 2008

Structure-activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl)propyl thiourea template

scientific article

Synapsin-1 and tau reciprocal O-GlcNAcylation and phosphorylation sites in mouse brain synaptosomes

scientific article published on 28 June 2013

TREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia

scientific article

The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer's disease pathogenesis

scientific article published on 12 January 2016

The role of cell type-specific mitochondrial dysfunction in the pathogenesis of Alzheimer's disease

scientific article published on 01 December 2019

The role of mitochondrial DNA mutation on neurodegenerative diseases

scientific article

Thrombospondin-1 prevents amyloid beta-mediated synaptic pathology in Alzheimer's disease

scientific article published on 14 September 2015

Thrombospondin-1 protects against Aβ-induced mitochondrial fragmentation and dysfunction in hippocampal cells

scientific article published on 20 February 2018

Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer's disease animal model

scientific article published on 30 August 2019

Transgenic potato expressing Abeta reduce Abeta burden in Alzheimer's disease mouse model

scientific article published on 21 November 2005

Two-Photon Absorbing Dyes with Minimal Autofluorescence in Tissue Imaging: Application to in Vivo Imaging of Amyloid-β Plaques with a Negligible Background Signal

scientific article published on 21 May 2015

UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination

scientific journal article

Upregulation of amyloid precursor protein by platelet-derived growth factor in hippocampal precursor cells

scientific article

Variation in effective stimulus patterns for induction of long-term potentiation across different layers of rat entorhinal cortex.

scientific article published in March 2002

Visualization of Altered Hippocampal Connectivity in an Animal Model of Alzheimer's Disease.

scientific article published on 27 February 2018

miR-351-5p/Miro2 axis contributes to hippocampal neural progenitor cell death via unbalanced mitochondrial fission

scientific article published on 23 December 2020

p53-dependent SIRT6 expression protects Aβ42-induced DNA damage

scientific article published on 9 May 2016

p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

scientific article published on 24 July 2017

β-Amyloid and α-synuclein cooperate to block SNARE-dependent vesicle fusion

scientific article published on 2 March 2015

Paulina is supported by:

About Paulina

Help