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List of works by Roman A Melnyk

An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth

scientific article published on 02 July 2020

Attenuated diphtheria toxin mediates siRNA delivery

scientific article published on 01 May 2020

Exploiting the diphtheria toxin internalization receptor enhances delivery of proteins to lysosomes for enzyme replacement therapy

scientific article published on 11 December 2020

Intracellular Delivery of Human Purine Nucleoside Phosphorylase by Engineered Diphtheria Toxin Rescues Function in Target Cells

scientific article published on 26 September 2018

Structures of distant diphtheria toxin homologs reveal functional determinants of an evolutionarily conserved toxin scaffold

scientific article published on 19 April 2022

The C. difficile toxin B membrane translocation machinery is an evolutionarily conserved protein delivery apparatus

scientific article published on 23 January 2020

The glucosyltransferase activity of C. difficile Toxin B is required for disease pathogenesis

scientific article published on 22 September 2020

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