List of works - Julianne T Djordjevic

Calcium Binding Protein Ncs1 Is Calcineurin Regulated in Cryptococcus neoformans and Essential for Cell Division and Virulence

scientific article published on 09 September 2020

Ccr4 promotes resolution of the endoplasmic reticulum stress response during host temperature adaptation in Cryptococcus neoformans

scientific article

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2.

scientific article

Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrity

scientific article published on 18 October 2007

Changes in glucosylceramide structure affect virulence and membrane biophysical properties of Cryptococcus neoformans

scientific article

Cryptococcal dissemination to the central nervous system requires the vacuolar calcium transporter Pmc1.

scientific article published on 7 November 2017

Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids

scientific article published on 10 November 2006

Cryptococcal phospholipase B1 is required for intracellular proliferation and control of titan cell morphology during macrophage infection

scientific article

Cryptococcal transmigration across a model brain blood-barrier: evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var. grubii strain H99 and Cryptococcus gattii strain R265.

scientific article published on 11 September 2015

De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans

scientific article

Detergent-resistant membrane fractions contribute to the total 1H NMR-visible lipid signal in cells

scientific article published on May 2003

Functional characterization of the hexose transporter Hxt13p: an efflux pump that mediates resistance to miltefosine in yeast

scientific article

Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects

scientific article published on 13 April 2014

Fungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity

scientific article published on 2 June 2015

Fungal Kinases With a Sweet Tooth: Pleiotropic Roles of Their Phosphorylated Inositol Sugar Products in the Pathogenicity of Cryptococcus neoformans Present Novel Drug Targeting Opportunities

scientific article published on 15 July 2019

Fungal Secretion: The Next-Gen Target of Antifungal Agents?

scientific article published in March 2018

HIV type 1 Nef increases the association of T cell receptor (TCR)-signaling molecules with T cell rafts and promotes activation-induced raft fusion

scientific article

IP3-4 kinase Arg1 regulates cell wall homeostasis and surface architecture to promote clearance of Cryptococcus neoformans infection in a mouse model.

scientific article published on 4 October 2017

Identification of Aph1, a phosphate-regulated, secreted, and vacuolar acid phosphatase in Cryptococcus neoformans

scientific article

Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence

scientific article published on April 2016

In vitro activity of miltefosine as a single agent and in combination with voriconazole or posaconazole against uncommon filamentous fungal pathogens

scientific article published on 16 July 2013

In vitro antifungal activities of bis(alkylpyridinium)alkane compounds against pathogenic yeasts and molds

scientific article

Influenza A Virus as a Predisposing Factor for Cryptococcosis

scientific article published on 26 September 2017

Inositol Polyphosphate Kinases, Fungal Virulence and Drug Discovery

scientific article

KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans

scientific article

Knockout of the Hmt1p Arginine Methyltransferase in Saccharomyces cerevisiae Leads to the Dysregulation of Phosphate-associated Genes and Processes

scientific article published on 11 September 2018

Lipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase

scientific article

Marsupial and monotreme cathelicidins display antimicrobial activity, including against methicillin-resistant Staphylococcus aureus

scientific article published on 27 September 2017

Microevolution of Cryptococcus neoformans Driven by Massive Tandem Gene Amplification

article

Miltefosine induces apoptosis-like cell death in yeast via Cox9p in cytochrome c oxidase

scientific article

Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence

scientific article published on 27 January 2012

Monitoring Glycolysis and Respiration Highlights Metabolic Inflexibility of Cryptococcus neoformans

scientific article published on 21 August 2020

N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring

scientific article published on 13 July 2006

Nitrogen metabolite repression of metabolism and virulence in the human fungal pathogen Cryptococcus neoformans

scientific article

Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH

scientific article published on 25 January 2017

Phospholipase C of Cryptococcus neoformans regulates homeostasis and virulence by providing inositol trisphosphate as a substrate for Arg1 kinase

scientific article published on 4 February 2013

Rapid microscopy and use of vital dyes: potential to determine viability of Cryptococcus neoformans in the clinical laboratory.

scientific article published on 27 January 2015

Role and mechanism of phosphatidylinositol-specific phospholipase C in survival and virulence of Cryptococcus neoformans

scientific article published on 4 June 2008

Role of Phospholipases in Fungal Fitness, Pathogenicity, and Drug Development – Lessons from Cryptococcus Neoformans ⬇️

scientific article published on November 11, 2010

Role of conserved active site residues in catalysis by phospholipase B1 from Cryptococcus neoformans

scientific article published on 9 August 2007

Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model

scientific article published on April 2004

SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans

scientific article

Sec6-dependent sorting of fungal extracellular exosomes and laccase of Cryptococcus neoformans

scientific article published on 5 February 2008

Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor

scientific article published on August 2005

Synthesis and Evaluation of a Series of Bis(pentylpyridinium) Compounds as Antifungal Agents

scientific article published on 19 June 2018

Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes

scientific article published on 23 July 2009

T cell antigen receptor (TCR) transmembrane peptides colocalize with TCR, not lipid rafts, in surface membranes

scientific article published in January 2002

T-cell antigen receptor peptides inhibit signal transduction within the membrane bilayer

scientific article published on November 2002

The Crz1/Sp1 transcription factor of Cryptococcus neoformans is activated by calcineurin and regulates cell wall integrity

scientific article

The Early Innate Immune Response to, and Phagocyte-Dependent Entry of, Cryptococcus neoformans Map to the Perivascular Space of Cortical Post-Capillary Venules in Neurocryptococcosis

scientific article published on 19 June 2018

The PHO signaling pathway directs lipid remodeling in Cryptococcus neoformans via DGTS synthase to recycle phosphate during phosphate deficiency

scientific article published on 21 February 2019

The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii

scientific article

Unravelling Secretion in Cryptococcus neoformans: More than One Way to Skin a Cat ⬇️

scientific article published on 06 September 2011

Why is a functional PHO pathway required by fungal pathogens to disseminate within a phosphate-rich host: A paradox explained by alkaline pH-simulated nutrient deprivation and expanded PHO pathway function.

scientific article published on 21 June 2018

List of works by Julianne T Djordjevic

Calcium Binding Protein Ncs1 Is Calcineurin Regulated in Cryptococcus neoformans and Essential for Cell Division and Virulence

Ccr4 promotes resolution of the endoplasmic reticulum stress response during host temperature adaptation in Cryptococcus neoformans

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2.

Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrity

Changes in glucosylceramide structure affect virulence and membrane biophysical properties of Cryptococcus neoformans

Cryptococcal dissemination to the central nervous system requires the vacuolar calcium transporter Pmc1.

Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids

Cryptococcal phospholipase B1 is required for intracellular proliferation and control of titan cell morphology during macrophage infection

Cryptococcal transmigration across a model brain blood-barrier: evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var. grubii strain H99 and Cryptococcus gattii strain R265.

De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans

Detergent-resistant membrane fractions contribute to the total 1H NMR-visible lipid signal in cells

Functional characterization of the hexose transporter Hxt13p: an efflux pump that mediates resistance to miltefosine in yeast

Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects

Fungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity

Fungal Kinases With a Sweet Tooth: Pleiotropic Roles of Their Phosphorylated Inositol Sugar Products in the Pathogenicity of Cryptococcus neoformans Present Novel Drug Targeting Opportunities

Fungal Secretion: The Next-Gen Target of Antifungal Agents?

HIV type 1 Nef increases the association of T cell receptor (TCR)-signaling molecules with T cell rafts and promotes activation-induced raft fusion

IP3-4 kinase Arg1 regulates cell wall homeostasis and surface architecture to promote clearance of Cryptococcus neoformans infection in a mouse model.

Identification of Aph1, a phosphate-regulated, secreted, and vacuolar acid phosphatase in Cryptococcus neoformans

Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence

In vitro activity of miltefosine as a single agent and in combination with voriconazole or posaconazole against uncommon filamentous fungal pathogens

In vitro antifungal activities of bis(alkylpyridinium)alkane compounds against pathogenic yeasts and molds

Influenza A Virus as a Predisposing Factor for Cryptococcosis

Inositol Polyphosphate Kinases, Fungal Virulence and Drug Discovery

KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans

Knockout of the Hmt1p Arginine Methyltransferase in Saccharomyces cerevisiae Leads to the Dysregulation of Phosphate-associated Genes and Processes

Lipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase

Marsupial and monotreme cathelicidins display antimicrobial activity, including against methicillin-resistant Staphylococcus aureus

Microevolution of Cryptococcus neoformans Driven by Massive Tandem Gene Amplification

Miltefosine induces apoptosis-like cell death in yeast via Cox9p in cytochrome c oxidase

Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence

Monitoring Glycolysis and Respiration Highlights Metabolic Inflexibility of Cryptococcus neoformans

N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring

Nitrogen metabolite repression of metabolism and virulence in the human fungal pathogen Cryptococcus neoformans

Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH

Phospholipase C of Cryptococcus neoformans regulates homeostasis and virulence by providing inositol trisphosphate as a substrate for Arg1 kinase

Rapid microscopy and use of vital dyes: potential to determine viability of Cryptococcus neoformans in the clinical laboratory.

Role and mechanism of phosphatidylinositol-specific phospholipase C in survival and virulence of Cryptococcus neoformans

Role of Phospholipases in Fungal Fitness, Pathogenicity, and Drug Development – Lessons from Cryptococcus Neoformans ⬇️

Role of conserved active site residues in catalysis by phospholipase B1 from Cryptococcus neoformans

Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model

SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans

Sec6-dependent sorting of fungal extracellular exosomes and laccase of Cryptococcus neoformans

Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor

Synthesis and Evaluation of a Series of Bis(pentylpyridinium) Compounds as Antifungal Agents

Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes

T cell antigen receptor (TCR) transmembrane peptides colocalize with TCR, not lipid rafts, in surface membranes

T-cell antigen receptor peptides inhibit signal transduction within the membrane bilayer

The Crz1/Sp1 transcription factor of Cryptococcus neoformans is activated by calcineurin and regulates cell wall integrity

The Early Innate Immune Response to, and Phagocyte-Dependent Entry of, Cryptococcus neoformans Map to the Perivascular Space of Cortical Post-Capillary Venules in Neurocryptococcosis

The PHO signaling pathway directs lipid remodeling in Cryptococcus neoformans via DGTS synthase to recycle phosphate during phosphate deficiency

The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii

Unravelling Secretion in Cryptococcus neoformans: More than One Way to Skin a Cat ⬇️

Why is a functional PHO pathway required by fungal pathogens to disseminate within a phosphate-rich host: A paradox explained by alkaline pH-simulated nutrient deprivation and expanded PHO pathway function.