List of works - Takashi Ikejima

Activation of ERK–p53 and ERK-Mediated Phosphorylation of Bcl-2 Are Involved in Autophagic Cell Death Induced by the c-Met Inhibitor SU11274 in Human Lung Cancer A549 Cells ⬇️

scientific article published on March 29, 2012

Autophagy enhanced phagocytosis of apoptotic cells by oridonin-treated human histocytic lymphoma U937 cells ⬇️

scientific article published on 02 December 2011

Autophagy induced by silibinin protects human epidermoid carcinoma A431 cells from UVB-induced apoptosis ⬇️

scientific article published on April 6, 2013

Daphnane-type diterpenes with inhibitory activities against human cancer cell lines from Daphne genkwa ⬇️

scientific article published on March 15, 2013

Dual effects of silibinin treatment on autophagy-regulated dermal apoptosis retardation and epidermal apoptosis up-regulation in UVB-induced skin inflammation ⬇️

scientific article published on May 10, 2012

Hydroxyl Radical (·OH) Played a Pivotal Role in Oridonin-Induced Apoptosis and Autophagy in Human Epidermoid Carcinoma A431 Cells ⬇️

scientific article published on January 1, 2012

In vivorecovery effect of silibinin treatment on streptozotocin-induced diabetic mice is associated with the modulations of sirt-1 expression and autophagy in pancreatic β-cell ⬇️

scientific article published on March 16, 2012

Inhibiting NF-κB activation and ROS production are involved in the mechanism of silibinin's protection against D-galactose-induced senescence ⬇️

scientific article published on December 15, 2010

Interference of silibinin with IGF-1R signalling pathways protects human epidermoid carcinoma A431 cells from UVB-induced apoptosis ⬇️

scientific article published on February 8, 2013

Interruption of Hepatocyte Growth Factor Signaling Augmented Oridonin-Induced Death in Human Non-small Cell Lung Cancer A549 Cells <i>via</i> c-Met-Nuclear Factor-κB-Cyclooxygenase-2 and c-Met-Bcl-2-Caspase-3 Pathways ⬇️

scientific article published on January 1, 2012

Interruption of mitochondrial complex IV activity and cytochrome c expression activated O2∙−-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R–PI3K–Akt and IGF-1R–PLC γ–PKC pathways ⬇️

scientific article published on June 17, 2011

Mechanism of autophagy induction and role of autophagy in antagonizing mitomycin C-induced cell apoptosis in silibinin treated human melanoma A375-S2 cells ⬇️

scientific article published on January 22, 2011

Negatively-regulated necroptosis by autophagy required caspase-6 activation in TNFα-treated murine fibrosarcoma L929 cells ⬇️

scientific article published on August 11, 2013

Nitric oxide (•NO) generation but not ROS plays a major role in silibinin-induced autophagic and apoptotic death in human epidermoid carcinoma A431 cells ⬇️

scientific article published on September 5, 2012

Nuclear Translocation of Tissue Type Transglutaminase during Sphingosine-Induced Cell Death: A Novel Aspect of the Enzyme with DNA Hydrolytic Activity ⬇️

scientific article published on 01 May 1998

Oridonin induces apoptosis and autophagy in murine fibrosarcoma L929 cells partly via NO-ERK-p53 positive-feedback loop signaling pathway ⬇️

scientific article published on July 30, 2012

Physalin A Induces Apoptotic Cell Death and Protective Autophagy in HT1080 Human Fibrosarcoma Cells ⬇️

scientific article published on May 6, 2013

Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells ⬇️

scientific article published on May 14, 2013

RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy ⬇️

scientific article published on September 20, 2012

Reactive oxygen species contribute to oridonin-induced apoptosis and autophagy in human cervical carcinoma HeLa cells ⬇️

scientific article published on September 5, 2011

Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells ⬇️

scientific article published on May 13, 2011

Silibinin Activated p53 and Induced Autophagic Death in Human Fibrosarcoma HT1080 Cells via Reactive Oxygen Species-p38 and c-Jun N-Terminal Kinase Pathways ⬇️

scientific article published on January 1, 2011

Silibinin Alleviates the Learning and Memory Defects in Overtrained Rats Accompanying Reduced Neuronal Apoptosis and Senescence

scientific article published on 17 May 2019

Silibinin activated ROS–p38–NF-κB positive feedback and induced autophagic death in human fibrosarcoma HT1080 cells ⬇️

scientific article published on 01 January 2011

Silibinin protects murine fibroblast L929 cells from UVB‐induced apoptosis through the simultaneous inhibition of ATM‐p53 pathway and autophagy ⬇️

scientific article published on August 2, 2013

Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ1-42 -induced reactive oxygen species/reactive nitrogen species generation

scientific article published on 06 February 2019

TNFα-Induced Necroptosis and Autophagy via Supression of the p38–NF-κB Survival Pathway in L929 Cells ⬇️

scientific article published on October 25, 2011

Two New Steroidal Saponins from the Rhizomes of Dioscorea panthaica and their Cytotoxic Activity ⬇️

scientific article published on December 1, 2001

Type I collagen inhibits adipogenic differentiation via YAP activation in vitro

scientific article published on 20 August 2019

Xanthoceraside attenuates amyloid β peptide25–35-induced learning and memory impairments in mice ⬇️

scientific article published on July 7, 2011

p53-mediated autophagy adjustment is involved in the protection of silibinin against murine dermal inflammation and epidermal apoptosis induced by UVB irradiation ⬇️

scientific article published on February 19, 2013

List of works by Takashi Ikejima