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List of works by Mason W. Freeman

A 12-week, randomized, double-blind, placebo-controlled, four-arm dose-finding phase 2 study evaluating bexagliflozin as monotherapy for adults with type 2 diabetes

scientific article published on 11 December 2019

A 24-week, randomized, double-blind, active-controlled clinical trial comparing bexagliflozin with sitagliptin as an adjunct to metformin for the treatment of type 2 diabetes in adults

scientific article published on 30 June 2019

A 96-week, multinational, randomized, double-blind, parallel-group, clinical trial evaluating the safety and effectiveness of bexagliflozin as a monotherapy for adults with type 2 diabetes

scientific article published on 08 August 2019

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

scientific article published on 17 September 2002

A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies

scientific article published in July 2006

ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters

scientific article

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol

scientific article published in December 2006

ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities

scientific article

Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.

scientific article published on 17 November 2004

Activation of signaling pathways by putative scavenger receptor class A (SR-A) ligands requires CD14 but not SR-A ⬇️

scientific article published on October 17, 2003

Atherosclerosis and innate immune signaling.

scientific article

C/EBPα induces adipogenesis through PPARγ: a unified pathway ⬇️

scientific article published on January 1, 2002

CD36 mediates the innate host response to beta-amyloid

scientific article

Case 22-2019: A 65-Year-Old Woman with Myopathy. Reply

scientific article published on 01 October 2019

Case 22-2019: A 65-Year-Old Woman with Weakness, Dark Urine, and Dysphagia

scientific article published on 01 July 2019

Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways

scientific article published on 01 October 2002

Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.

scientific article published on February 2004

Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury

scientific article

Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial

scientific article published on July 2015

Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia

scientific article published on 21 March 2005

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

scientific article

Exome sequencing in suspected monogenic dyslipidemias

scientific article

Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association

scientific article

Generalized rank tests for replicated microarray data

scientific article

Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects

scientific article published on 15 February 2007

High-density lipoprotein-mediated cholesterol efflux capacity is improved by treatment with antiretroviral therapy in acute human immunodeficiency virus infection

scientific article

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment

scientific article published on 01 July 2005

Local Injection of Bevacizumab (Avastin) and Angiolytic KTP Laser Treatment of Recurrent Respiratory Papillomatosis of the Vocal Folds: A Prospective Study ⬇️

scientific article published on October 1, 2011

Long-term effects of patiromer for hyperkalaemia treatment in patients with mild heart failure and diabetic nephropathy on angiotensin-converting enzymes/angiotensin receptor blockers: results from AMETHYST-DN

scientific article published on 16 May 2018

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice

scientific article published on 23 October 2008

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

scientific article

NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges

scientific article

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I

scientific article

Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice

scientific article published in October 2002

Nonparametric methods for microarray data based on exchangeability and borrowed power

scientific article

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home

scientific article

Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia

scientific article

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux

scientific article

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

scientific article published on 14 March 2004

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis

scientific article published in November 2004

Risk factors for coronary artery disease in patients with elevated high-density lipoprotein cholesterol

scientific article published on 2 November 2006

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter

scientific journal article

Safety and Dosing of Bevacizumab (Avastin) for the Treatment of Recurrent Respiratory Papillomatosis ⬇️

scientific article published on September 1, 2012

Safety and Effectiveness of Bexagliflozin in Patients With Type 2 Diabetes Mellitus and Stage 3a/3b CKD

scientific article published on 14 May 2019

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

scientific article

Scavenger receptors in atherosclerosis: beyond lipid uptake

scientific article

Statins, cholesterol, and the prevention of coronary heart disease

scientific article published in February 2006

Targeting Innate Immunity for CV Benefit

scientific article published on January 2008

The Creating an Optimal Warfarin Nomogram (CROWN) Study ⬇️

scientific article published on November 24, 2011

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades

scientific article published on 14 September 2004

US immigration order strikes against biotech.

scientific article

Wild type and Tangier disease ABCA1 mutants modulate cellular amyloid-β production independent of cholesterol efflux activity

scientific article

eLiXiRs for restraining inflammation

scientific article published on 01 February 2003

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