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List of works by Adam V Wisnewski

A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge

scientific article

Analysis of lung gene expression reveals a role for Cl- channels in diisocyanate induced airway eosinophilia in a mouse model of asthma pathology

journal article published in 2020

Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate

scientific article published on 15 May 2010

Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel

journal article published in 2021

Biomonitoring Hexamethylene Diisocyanate (HDI) Exposure Based on Serum Levels of HDI-Specific IgG ⬇️

scientific article published on March 26, 2012

Biotransformation and rearrangement of laromustine

journal article published in 2016

Characterization of diisocyanate haptenation of serum albumin by multiplexed tandem mass spectrometry ⬇️

abstract published in 2013

Comparative analyses of methods used to prepare diisocyanate conjugates; implications in clinical assay development ⬇️

abstract published in 2015

Connecting glutathione with immune responses to occupational methylene diphenyl diisocyanate exposure ⬇️

scientific article published on June 20, 2013

Development and Validation of LC-MS-MS Assay for the Determination of the Emerging Alkylating Agent Laromustine and Its Active Metabolite in Human Plasma

Development and utilization of a surrogate SARS-CoV-2 viral neutralization assay to assess mRNA vaccine responses

journal article published in 2022

Development and validation of LC-MS-MS assay for the determination of the emerging alkylating agent Laromustine and its active metabolite in human plasma

journal article published in 2019

Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation

scientific article published in May 2003

Dilysine-methylene diphenyl diisocyanate (MDI), a urine biomarker of MDI exposure?

journal article published in 2019

Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies

scientific article

Glutathione reaction products with a chemical allergen, methylene-diphenyl diisocyanate, stimulate alternative macrophage activation and eosinophilic airway inflammation

journal article published in 2015

Hexamethylene diisocyanate (HDI) vapor reactivity with glutathione and subsequent transfer to human albumin ⬇️

scientific article published on November 23, 2012

Human IgG and IgA responses to COVID-19 mRNA vaccines

journal article published in 2021

Human gamma/delta T-cell proliferation and IFN-gamma production induced by hexamethylene diisocyanate

journal article published in 2003

Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses ⬇️

scientific article published on March 17, 2011

Immunochemical detection of the occupational allergen, methylene diphenyl diisocyanate (MDI), in situ

journal article published in 2016

Immunogenic amino acid motifs and linear epitopes of COVID-19 mRNA vaccines

journal article published in 2021

Impact of recent innovations in the use of mass cytometry in support of drug development

journal article published in 2015

In vitro cleavage of diisocyanate-glutathione conjugates by human gamma-glutamyl transpeptidase-1

journal article published in 2016

Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: initial one-year follow-up.

scientific article

Isocyanate vapor-induced antigenicity of human albumin

journal article published in 2004

LC-UV-MS and MS/MS characterize glutathione reactivity with different isomers (2,2' and 2,4' vs. 4,4') of methylene diphenyl-diisocyanate ⬇️

journal article published in 2019

Mass spectrometry-based analysis of murine bronchoalveolar lavage fluid following respiratory exposure to 4,4'-methylene diphenyl diisocyanate aerosol

journal article published in 2018

Metabolic disposition of the anti-cancer agent [(14)C]laromustine in male rats

journal article published in 2015

Methylene-diphenyl diisocyanate (MDI) usage, exposure and health outcomes among polyurethane spray foam insulators in the construction industry ⬇️

abstract published in 2013

Molecular characterization and experimental utility of monoclonal antibodies with specificity for aliphatic di- and polyisocyanates

journal article published in 2020

Monoclonal antibodies (mAbs) to methylene diphenyl diisocyanate (MDI) and toluene diisocyanate (TDI) conjugated protein: research and potential biomonitoring applications ⬇️

abstract published in 2013

Mouse models of diisocyanate asthma

scientific article

Polymerization of hexamethylene diisocyanate in solution and a 260.23 m/z [M+H]+ ion in exposed human cells

journal article published in 2018

Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients

journal article published in 2017

Reaction products of hexamethylene diisocyanate vapors with "self" molecules in the airways of rabbits exposed via tracheostomy

journal article published in 2018

Recent developments in diisocyanate asthma

scientific article

Severe asthma and death in a worker using methylene diphenyl diisocyanate MDI asthma death

journal article published in 2022

Subclinical immunologic and physiologic responses in hexamethylene diisocyanate-exposed auto body shop workers

journal article published in 2001

The Influence of diisocyanate antigen preparation methodology on monoclonal and serum antibody recognition

journal article published in 2016

Toluene diisocyanate reactivity with glutathione across a vapor/liquid interface and subsequent transcarbamoylation of human albumin

journal article published in 2011

UPLC-MS for metabolomics: a giant step forward in support of pharmaceutical research

journal article published in 2017

Vapor conjugation of toluene diisocyanate to specific lysines of human albumin ⬇️

scientific article published on December 13, 2011

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