List of works - Ruth Brack-Werner

A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity

scientific article published on 3 July 2012

A new model for post-integration latency in macroglial cells to study HIV-1 reservoirs of the brain

scientific article published on June 2015

A novel role for the viral Rev protein in promoting resistance to superinfection by human immunodeficiency virus type 1.

scientific article

ATO (Arsenic Trioxide) Effects on Promyelocytic Leukemia Nuclear Bodies Reveals Antiviral Intervention Capacity

scientific article published on 27 February 2020

Activation of a HERV-H LTR induces expression of an aberrant calbindin protein in human prostate carcinoma cells

Advanced identification of global bioactivity hotspots via screening of the metabolic fingerprint of entire ecosystems

scientific article published on 28 January 2020

Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1)

scientific article

Analysis of nuclear targeting activities of transport signals in the human immunodeficiency virus Rev protein

scientific article

Analysis of the influence of subcellular localization of the HIV Rev protein on Rev-dependent gene expression by multi-fluorescence live-cell imaging

scientific article published on February 2006

Aqueous extracts of the marine brown alga Lobophora variegata inhibit HIV-1 infection at the level of virus entry into cells

scientific article

Biological evaluation of molecules of the azaBINOL class as antiviral agents: Inhibition of HIV-1 RNase H activity by 7-isopropoxy-8-(naphth-1-yl)quinoline

scientific article published on 28 June 2019

Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus

scientific article

Chemoenzymatic Total Synthesis of Sorbicatechol Structural Analogues and Evaluation of Their Antiviral Potential

scientific article published on 19 November 2019

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

scientific article

Discovery of the Streptoketides by Direct Cloning and Rapid Heterologous Expression of a Cryptic PKS II Gene Cluster from Streptomyces sp. Tü 6314

scientific article published on 24 December 2019

Dual role of the chromatin-binding factor PHF13 in the pre- and post-integration phases of HIV-1 replication

scientific article published on October 2017

EASY-HIT: HIV Full-Replication Technology for Broad Discovery of Multiple Classes of HIV Inhibitors ⬇️

scientific article published on September 27, 2010

Elucidating effects of long-term expression of HIV-1 Nef on astrocytes by microarray, promoter, and literature analyses

scientific article published on September 2005

Functional analysis of backbone cyclic peptides bearing the arm domain of the HIV-1 Rev protein: characterization of the karyophilic properties and inhibition of Rev-induced gene expression

scientific article

Functional nuclear topography of transcriptionally inducible extra-chromosomal transgene clusters

scientific article

Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures

scientific article published in 2019

HIV-1 replication in human immune cells is independent of TAR DNA binding protein 43 (TDP-43) expression

scientific article

Heterogenous nuclear ribonucleoprotein Q increases protein expression from HIV-1 Rev-dependent transcripts

scientific article published on 16 May 2013

Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein

scientific article published on 5 October 2009

Identification of a novel Rev-interacting cellular protein

scientific article

Integrated functional and bioinformatics approach for the identification and experimental verification of RNA signals: application to HIV-1 INS.

scientific article

Live-cell assay for simultaneous monitoring of expression and interaction of proteins

scientific article published in December 2006

Long-term HIV-1 infection of neural progenitor populations

scientific article published on November 2007

Macrophages and their relevance in Human Immunodeficiency Virus Type I infection

scientific article

Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors

article

Modulation of human endogenous retrovirus (HERV) transcription during persistent and de novo HIV-1 infection

scientific article

Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno-Associated Viral Vector rAAV9P1

scientific article published on 10 April 2022

Novel regulation of HIV-1 replication and pathogenicity: Rev inhibition of integration

scientific article published on 29 October 2009

Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration

scientific article

Potent in vitro antiviral activity of Cistus incanus extract against HIV and Filoviruses targets viral envelope proteins

scientific article published on 2 February 2016

Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin

scientific article published on 28 January 2020

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

scientific article published on 18 December 2019

Stably integrated and expressed retroviral sequences can influence nuclear location and chromatin condensation of the integration locus

scientific article published on 14 March 2012

Stimulation of the HIV-1 integrase enzymatic activity and cDNA integration by a peptide derived from the integrase protein

scientific article

Structural Basis for Homodimerization of the Src-associated during Mitosis, 68-kDa Protein (Sam68) Qua1 Domain

scientific article

Supramolecular combinations of humic polyanions as potent microbicides with polymodal anti-HIV-activities

article

Synthetic AAV/CRISPR vectors for blocking HIV-1 expression in persistently infected astrocytes

scientific article published on 9 November 2017

T cells with low CD2 levels express reduced restriction factors and are preferentially infected in therapy naïve chronic HIV-1 patients

scientific article published on September 2017

Targeting of nonkaryophilic cell-permeable peptides into the nuclei of intact cells by covalently attached nuclear localization signals

scientific article published on 01 July 2002

The NORMAN Association and the European Partnership for Chemicals Risk Assessment (PARC): let’s cooperate!

scientific article published on 20 July 2020

The intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylation

scientific article

The root extract of the medicinal plant Pelargonium sidoides is a potent HIV-1 attachment inhibitor

scientific article (publication date: 2014)

[Are there strategies against latent infection?]

scientific article published on 01 June 2018

List of works by Ruth Brack-Werner

A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity

A new model for post-integration latency in macroglial cells to study HIV-1 reservoirs of the brain

A novel role for the viral Rev protein in promoting resistance to superinfection by human immunodeficiency virus type 1.

ATO (Arsenic Trioxide) Effects on Promyelocytic Leukemia Nuclear Bodies Reveals Antiviral Intervention Capacity

Activation of a HERV-H LTR induces expression of an aberrant calbindin protein in human prostate carcinoma cells

Advanced identification of global bioactivity hotspots via screening of the metabolic fingerprint of entire ecosystems

Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1)

Analysis of nuclear targeting activities of transport signals in the human immunodeficiency virus Rev protein

Analysis of the influence of subcellular localization of the HIV Rev protein on Rev-dependent gene expression by multi-fluorescence live-cell imaging

Aqueous extracts of the marine brown alga Lobophora variegata inhibit HIV-1 infection at the level of virus entry into cells

Biological evaluation of molecules of the azaBINOL class as antiviral agents: Inhibition of HIV-1 RNase H activity by 7-isopropoxy-8-(naphth-1-yl)quinoline

Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus

Chemoenzymatic Total Synthesis of Sorbicatechol Structural Analogues and Evaluation of Their Antiviral Potential

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

Discovery of the Streptoketides by Direct Cloning and Rapid Heterologous Expression of a Cryptic PKS II Gene Cluster from Streptomyces sp. Tü 6314

Dual role of the chromatin-binding factor PHF13 in the pre- and post-integration phases of HIV-1 replication

EASY-HIT: HIV Full-Replication Technology for Broad Discovery of Multiple Classes of HIV Inhibitors ⬇️

Elucidating effects of long-term expression of HIV-1 Nef on astrocytes by microarray, promoter, and literature analyses

Functional analysis of backbone cyclic peptides bearing the arm domain of the HIV-1 Rev protein: characterization of the karyophilic properties and inhibition of Rev-induced gene expression

Functional nuclear topography of transcriptionally inducible extra-chromosomal transgene clusters

Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures

HIV-1 replication in human immune cells is independent of TAR DNA binding protein 43 (TDP-43) expression

Heterogenous nuclear ribonucleoprotein Q increases protein expression from HIV-1 Rev-dependent transcripts

Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein

Identification of a novel Rev-interacting cellular protein

Integrated functional and bioinformatics approach for the identification and experimental verification of RNA signals: application to HIV-1 INS.

Live-cell assay for simultaneous monitoring of expression and interaction of proteins

Long-term HIV-1 infection of neural progenitor populations

Macrophages and their relevance in Human Immunodeficiency Virus Type I infection

Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors

Modulation of human endogenous retrovirus (HERV) transcription during persistent and de novo HIV-1 infection

Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno-Associated Viral Vector rAAV9P1

Novel regulation of HIV-1 replication and pathogenicity: Rev inhibition of integration

Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration

Potent in vitro antiviral activity of Cistus incanus extract against HIV and Filoviruses targets viral envelope proteins

Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin

Proceedings of the Frontiers of Retrovirology Conference 2016.

SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

Stably integrated and expressed retroviral sequences can influence nuclear location and chromatin condensation of the integration locus

Stimulation of the HIV-1 integrase enzymatic activity and cDNA integration by a peptide derived from the integrase protein

Structural Basis for Homodimerization of the Src-associated during Mitosis, 68-kDa Protein (Sam68) Qua1 Domain

Supramolecular combinations of humic polyanions as potent microbicides with polymodal anti-HIV-activities

Synthetic AAV/CRISPR vectors for blocking HIV-1 expression in persistently infected astrocytes

T cells with low CD2 levels express reduced restriction factors and are preferentially infected in therapy naïve chronic HIV-1 patients

Targeting of nonkaryophilic cell-permeable peptides into the nuclei of intact cells by covalently attached nuclear localization signals

The NORMAN Association and the European Partnership for Chemicals Risk Assessment (PARC): let’s cooperate!

The intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylation

The root extract of the medicinal plant Pelargonium sidoides is a potent HIV-1 attachment inhibitor

[Are there strategies against latent infection?]