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List of works by David L Wyles

1979. Time to Viral Suppression Does Not Impact SVR in Patients Treated With Glecaprevir/Pibrentasvir for 8 Weeks

3-drug synergistic interactions of small molecular inhibitors of hepatitis C virus replication

scientific article

A modular approach to synthetic RNA binders of the hepatitis C virus internal ribosome entry site.

scientific article

Abacavir pharmacokinetics in hepatic dysfunction

scientific article published in March 2005

About This Continuing Medical Education Activity

scientific article published on July 2016

Alkoxyalkyl esters of 9-(s)-(3-hydroxy-2-phosphonomethoxypropyl) adenine are potent and selective inhibitors of hepatitis B virus (HBV) replication in vitro and in HBV transgenic mice in vivo

scientific article published on 27 April 2009

All-oral combination of ledipasvir, vedroprevir, tegobuvir, and ribavirin in treatment-naïve patients with genotype 1 HCV infection

scientific article published on 28 May 2014

Analysis of Subgroup Differences in the ION-3 Trial of Ledipasvir-Sofosbuvir in Chronic Hepatitis C Infection

scientific article

Antiretroviral drug pharmacokinetics in hepatitis with hepatic dysfunction

scientific article

Antiviral drug advances in the treatment of human immunodeficiency virus (HIV) and chronic hepatitis C virus (HCV).

scientific article published on 05 July 2012

Antiviral resistance and the future landscape of hepatitis C virus infection therapy

scientific article published on March 2013

Beyond telaprevir and boceprevir: resistance and new agents for hepatitis C virus infection ⬇️

scientific article published on October 1, 2012

CROI 2015: Highlights of Viral Hepatitis Therapy

scientific article published on March 2015

CROI 2016: Viral Hepatitis and Liver Fibrosis.

scientific article published on May 2016

CROI 2017: Highlights of Advances in Viral Hepatitis and Liver Fibrosis

scientific article published on May 2017

CROI 2018: Highlights of Viral Hepatitis.

scientific article

CROI 2019: highlights of viral hepatitis.

scientific article published in April 2019

Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA

scientific article

Corticosteroids for Posttransplant Immune Reconstitution Syndrome in Cryptococcus gattii Meningoencephalitis: Case Report and Literature Review

scientific article published on 23 October 2019

Daclatasvir plus Sofosbuvir for HCV in Patients Coinfected with HIV-1.

scientific article published on 21 July 2015

Development of herpes simplex virus disease in patients who are receiving cidofovir

scientific article

Early identification and linkage to care of persons with chronic hepatitis B virus infection--three U.S. sites, 2012-2014.

scientific article published on May 2014

Efficacy and Safety of Ledipasvir/Sofosbuvir With and Without Ribavirin in Patients With Chronic HCV Genotype 1 Infection Receiving Opioid Substitution Therapy: Analysis of Phase 3 ION Trials

scientific article published on 23 August 2016

Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in Patients With Chronic Hepatitis C Virus Genotype 1 Infection Receiving Opioid Substitution Therapy: A Post Hoc Analysis of 12 Clinical Trials

Emerging complexities with hepatitis C virus direct-acting antiviral regimens: Less is still Way more

scientific article published on 16 September 2016

Evaluation of ITX 5061, a Scavenger Receptor B1 Antagonist: Resistance Selection and Activity in Combination With Other Hepatitis C Virus Antivirals ⬇️

scientific article published on February 15, 2012

Functional conservation despite structural divergence in ligand-responsive RNA switches

scientific article

Glecaprevir and pibrentasvir yield high response rates in patients with HCV genotype 1-6 without cirrhosis

scientific article published on 12 April 2017

Glecaprevir/pibrentasvir for hepatitis C virus genotype 3 patients with cirrhosis and/or prior treatment experience: A partially randomized phase 3 clinical trial

scientific article published on 19 September 2017

Grazoprevir, Ruzasvir, and Uprifosbuvir for HCV After NS5A Treatment Failure

scientific article published on 7 July 2017

Hepatitis C virus drug resistance: implications for clinical management

scientific article published on December 2012

Hepatitis virus coinfection in the Strategic Management of Antiretroviral Therapy (SMART) study: a marker for nonliver, non-opportunistic disease mortality

scientific article published in December 2008

High Efficacy of ABT-493 and ABT-530 Treatment in Patients With HCV Genotype 1 or 3 Infection and Compensated Cirrhosis

scientific article published on 22 July 2016

High incidence of serious adverse events in HIV-infected patients treated with a telaprevir-based hepatitis C virus treatment regimen

scientific article

High prevalence of subtype F in newly diagnosed HIV-1 persons in northwest Spain and evidence for impaired treatment response

scientific article published on July 2014

Incident Hepatitis C Virus Infection among US HIV-Infected Men Enrolled in Clinical Trials ⬇️

scientific article published on January 31, 2011

Increasing Hepatitis C treatment uptake among HIV-infected patients using an HIV primary care model

scientific article published on 28 March 2013

Infrequent development of resistance in genotype 1-6 hepatitis C virus-infected subjects treated with sofosbuvir in phase 2 and 3 clinical trials.

scientific article published on 28 September 2014

Interferon γ-induced protein 10 kinetics in treatment-naive versus treatment-experienced patients receiving interferon-free therapy for hepatitis C virus infection: implications for the innate immune response

scientific article

Intrahepatic Viral Kinetics during Direct-Acting Antivirals for Hepatitis C in HIV Co-infection:The ACTG A5335S Substudy

scientific article published on 23 March 2020

Ledipasvir-sofosbuvir plus ribavirin for patients with genotype 1 hepatitis C virus previously treated in clinical trials of sofosbuvir regimens

scientific article published on 27 April 2015

Long-term persistence of HCV NS5A resistance associated substitutions after treatment with the HCV NS5A inhibitor, ledipasvir, without sofosbuvir

scientific article

Management of Hepatitis C/HIV Coinfection in the Era of Highly Effective Hepatitis C Virus Direct-Acting Antiviral Therapy

scientific article published on July 2016

Moving beyond interferon alfa: investigational drugs for hepatitis C virus infection

scientific article published on October 2010

News on HIV-HCV Coinfection: Update From the 2015 GEHEP Conference

scientific article

Ombitasvir, paritaprevir co-dosed with ritonavir, dasabuvir, and ribavirin for hepatitis C in patients co-infected with HIV-1: a randomized trial

scientific article published on March 2015

Patient-reported outcomes in patients co-infected with hepatitis C virus and human immunodeficiency virus treated with sofosbuvir and velpatasvir: The ASTRAL-5 study

scientific article published on 4 May 2017

Post-treatment resistance analysis of hepatitis C virus from phase II and III clinical trials of ledipasvir/sofosbuvir

scientific article

Primary Incidence of Hepatitis C Virus Infection Among HIV-Infected Men Who Have Sex With Men in San Diego, 2000-2015

article

Raltegravir pharmacokinetics before and during treatment with ombitasvir, paritaprevir/ritonavir plus dasabuvir in adults with human immunodeficiency virus-1 and hepatitis C virus coinfection: AIDS Clinical Trials Group sub-study A5334s

scientific article published on 12 December 2019

Regimens for Patients Coinfected with Human Immunodeficiency Virus

scientific article published on 29 August 2015

Reliability and predictive validity of a hepatitis-related symptom inventory in HIV-infected individuals referred for Hepatitis C treatment ⬇️

scientific article published on August 10, 2011

Resistance to DAAs: When to Look and When It Matters

scientific article published on 7 November 2017

Rong's numbers: accelerating progress in HCV therapeutic research

scientific article published in May 2010

Safety and Efficacy of Ombitasvir, Paritaprevir With Ritonavir ± Dasabuvir With or Without Ribavirin in Patients With Human Immunodeficiency Virus-1 and Hepatitis C Virus Genotype 1 or Genotype 4 Coinfection: TURQUOISE-I Part 2.

scientific article published on 22 July 2017

Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study

scientific article published on 16 September 2013

Similar Low Rates of HCV Recurrence in HCV/HIV- and HCV-Infected Participants who Achieved SVR After DAA Treatment: Interim Results From the ACTG A5320 Viral Hepatitis C Infection Long-term Cohort Study (V-HICS).

scientific article

Sofosbuvir With Velpatasvir in Treatment-Naive Noncirrhotic Patients With Genotype 1 to 6 Hepatitis C Virus Infection: A Randomized Trial

scientific article

Sofosbuvir and Velpatasvir for the Treatment of HCV in Patients Coinfected with HIV-1: an Open-Label, Phase 3 Study

scientific article published on 29 March 2017

Sofosbuvir-Based Direct-Acting Antiviral Therapies for HCV in People Receiving Opioid Substitution Therapy: An Analysis of Phase 3 Studies

scientific article published on 9 February 2018

Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitches ⬇️

scientific article published on March 19, 2012

Synergy of Small Molecular Inhibitors of Hepatitis C Virus Replication Directed at Multiple Viral Targets

scientific article (publication date: March 2007)

Synergy of a Hepatitis C Virus (HCV) NS4A Antagonist in Combination with HCV Protease and Polymerase Inhibitors

scientific article

Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy)propyl]nucleoside alkoxyalkyl esters: inhibitors of hepatitis C virus and HIV-1 replication

scientific article

TURQUOISE-I Part 1b: Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir with Ribavirin for Hepatitis C Virus Infection in HIV-1 Coinfected Patients on Darunavir

scientific article published on 14 March 2017

Temporal dynamics of inflammatory cytokines/chemokines during sofosbuvir and ribavirin therapy for genotype 2 and 3 hepatitis C infection

scientific article

The Impact of Direct-Acting Antivirals in the Hepatitis C-Sustained Viral Response in Human Immunodeficiency Virus-Infected Patients With Ongoing Barriers to Care.

scientific article

The Octadecyloxyethyl Ester of (S)-9-[3-Hydroxy-2-(Phosphonomethoxy) Propyl]Adenine Is a Potent and Selective Inhibitor of Hepatitis C Virus Replication in Genotype 1A, 1B, and 2A Replicons

scientific article

The hepatitis C cascade of care among HIV infected patients: a call to address ongoing barriers to care

scientific article

Understanding Hepatitis C Virus Drug Resistance: Clinical Implications for Current and Future Regimens

scientific article

Update on hepatitis C virus resistance to direct-acting antiviral agents

scientific article

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