List of works - Giedrius Sasnauskas

A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3'-5' and 5'-3' strands by rotating a single active site

scientific article

Activity and structure of EcoKMcrA

Allosteric communication network in the tetrameric restriction endonuclease Bse634I.

scientific article published on 24 August 2006

CRISPR adaptation from a structural perspective

scientific article published on 19 June 2020

Catalytic activity control of restriction endonuclease--triplex forming oligonucleotide conjugates.

scientific article published on 30 January 2012

Chemical display of pyrimidine bases flipped out by modification-dependent restriction endonucleases of MspJI and PvuRts1I families

scientific article

Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence

scientific article

Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping

scientific article published on 01 December 2019

DNA recognition by Arabidopsis transcription factors ABI3 and NGA1

scientific article published on 21 September 2018

DNA synapsis through transient tetramerization triggers cleavage by Ecl18kI restriction enzyme.

scientific article

DNA-Endonuclease Complex Dynamics by Simultaneous FRET and Fluorophore Intensity in Evanescent Field

scientific article published in March 2017

Degenerate sequence recognition by the monomeric restriction enzyme: single mutation converts BcnI into a strand-specific nicking endonuclease.

scientific article published on 11 January 2011

Domain organization and functional analysis of type IIS restriction endonuclease Eco31I

scientific article published on 22 July 2008

Generation and characterization of new highly thermostable and processive M-MuLV reverse transcriptase variants.

scientific article

How the Bfi I restriction enzyme uses one active site to cut two DNA strands ⬇️

scientific article published on May 15, 2003

Oligomeric structure diversity within the GIY-YIG nuclease family

scientific article published on 30 January 2009

Plasmid DNA Cleavage byMunI Restriction Enzyme: Single-Turnover and Steady-State Kinetic Analysis†

article

Probing the dynamics of restriction endonuclease NgoMIV-DNA interaction by single-molecule FRET.

scientific article

Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC

scientific article published on 19 September 2018

Restriction enzyme Ecl18kI-induced DNA looping dynamics by single-molecule FRET.

scientific article published on 14 July 2014

Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling

scientific article published on 30 November 2023

Simultaneous binding of three recognition sites is necessary for a concerted plasmid DNA cleavage by EcoRII restriction endonuclease

scientific article published on 28 February 2006

Site-specific DNA transesterification catalyzed by a restriction enzyme

scholarly article

Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1.

scientific article published in May 2018

Structural insight into the specificity of the B3 DNA-binding domains provided by the co-crystal structure of the C-terminal fragment of BfiI restriction enzyme

scientific article

Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI.

scientific article published on 22 May 2015

Target site cleavage by the monomeric restriction enzyme BcnI requires translocation to a random DNA sequence and a switch in enzyme orientation

scientific article published on 19 July 2011

Template-directed addition of nucleosides to DNA by the BfiI restriction enzyme

scientific article

Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family

scientific article published on 17 December 2007

The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA

scientific article

The link between restriction endonuclease fidelity and oligomeric state: a study with Bse634I

scientific article published on 22 July 2012

The metal-independent type IIs restriction enzyme BfiI is a dimer that binds two DNA sites but has only one catalytic centre

scientific article

UbaLAI is a monomeric Type IIE restriction enzyme.

scientific article

List of works by Giedrius Sasnauskas

A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3'-5' and 5'-3' strands by rotating a single active site

Activity and structure of EcoKMcrA

Allosteric communication network in the tetrameric restriction endonuclease Bse634I.

CRISPR adaptation from a structural perspective

Catalytic activity control of restriction endonuclease--triplex forming oligonucleotide conjugates.

Chemical display of pyrimidine bases flipped out by modification-dependent restriction endonucleases of MspJI and PvuRts1I families

Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence

Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping

DNA recognition by Arabidopsis transcription factors ABI3 and NGA1

DNA synapsis through transient tetramerization triggers cleavage by Ecl18kI restriction enzyme.

DNA-Endonuclease Complex Dynamics by Simultaneous FRET and Fluorophore Intensity in Evanescent Field

Degenerate sequence recognition by the monomeric restriction enzyme: single mutation converts BcnI into a strand-specific nicking endonuclease.

Domain organization and functional analysis of type IIS restriction endonuclease Eco31I

Generation and characterization of new highly thermostable and processive M-MuLV reverse transcriptase variants.

How the Bfi I restriction enzyme uses one active site to cut two DNA strands ⬇️

Oligomeric structure diversity within the GIY-YIG nuclease family

Plasmid DNA Cleavage byMunI Restriction Enzyme: Single-Turnover and Steady-State Kinetic Analysis†

Probing the dynamics of restriction endonuclease NgoMIV-DNA interaction by single-molecule FRET.

Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC

Restriction enzyme Ecl18kI-induced DNA looping dynamics by single-molecule FRET.

Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling

Simultaneous binding of three recognition sites is necessary for a concerted plasmid DNA cleavage by EcoRII restriction endonuclease

Site-specific DNA transesterification catalyzed by a restriction enzyme

Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1.

Structural insight into the specificity of the B3 DNA-binding domains provided by the co-crystal structure of the C-terminal fragment of BfiI restriction enzyme

Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI.

Target site cleavage by the monomeric restriction enzyme BcnI requires translocation to a random DNA sequence and a switch in enzyme orientation

Template-directed addition of nucleosides to DNA by the BfiI restriction enzyme

Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family

The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA

The link between restriction endonuclease fidelity and oligomeric state: a study with Bse634I

The metal-independent type IIs restriction enzyme BfiI is a dimer that binds two DNA sites but has only one catalytic centre

UbaLAI is a monomeric Type IIE restriction enzyme.