List of works - Wolfgang Nacken

A homologue of the human MSS1 gene, a positive modulator of HIV-1 gene expression, is massively expressed in Xenopus oocytes

scientific article

Absence of S100A12 in mouse: implications for RAGE-S100A12 interaction

scientific article published on 01 December 2003

Activation of c-jun N-terminal kinase upon influenza A virus (IAV) infection is independent of pathogen-related receptors but dependent on amino acid sequence variations of IAV NS1.

scientific article

Analysis of the MRP8-MRP14 protein-protein interaction by the two-hybrid system suggests a prominent role of the C-terminal domain of S100 proteins in dimer formation

scientific article

Biochemical characterization of the murine S100A9 (MRP14) protein suggests that it is functionally equivalent to its human counterpart despite its low degree of sequence homology

scientific article

Computational searches for missing orthologs: the case of S100A12 in mice

scientific article published in January 2004

Double-stranded RNA induces MMP-9 gene expression in HaCaT keratinocytes by tumor necrosis factor-α.

scientific article published on June 2011

Double-stranded RNA induces S100 gene expression by a cycloheximide-sensitive factor

scientific article published on 29 December 2011

Expression of S100A8/A9 in HaCaT keratinocytes alters the rate of cell proliferation and differentiation

scientific article published on 28 December 2010

Expression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis

scientific article published on 27 June 2003

Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes.

scientific article published on 3 October 2006

HaCaT Keratinocytes Overexpressing the S100 Proteins S100A8 and S100A9 Show Increased NADPH Oxidase and NF-κB Activities

scientific article published on 12 April 2007

Identification of a novel HIV-1 TAR RNA bulge binding protein

scientific article published on August 1994

Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked

scientific article published on 11 January 2017

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

scientific article

Interaction between S100A8/A9 and annexin A6 is involved in the calcium-induced cell surface exposition of S100A8/A9.

scientific article published on 11 September 2008

Interaction of S100A8/S100A9-arachidonic acid complexes with the scavenger receptor CD36 may facilitate fatty acid uptake by endothelial cells

scientific article

Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro

scientific article

MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes

scientific article

Members of the AAA-gene family are involved in early embryogenesis of vertebrates

scientific article published in October 1997

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

scientific article published in Science

Molecular analysis of the mouse S100A9 gene and evidence that the myeloid specific transcription factor C/EBPepsilon is not required for the regulation of the S100A9/A8 gene expression in neutrophils

scientific article

Molecular characterisation of the genomic locus of the mouse MRP8 gene

scientific article

Mrp-8 and -14 mediate CNS injury in focal cerebral ischemia

scientific article published on 14 October 2009

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

scientific article (publication date: September 2007)

Myeloid-related protein (MRP)-8 from cervico-vaginal secretions activates HIV replication

scientific article

Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis

scientific article published on 30 November 2007

Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans

scientific article published in October 2009

PAR1 contributes to influenza A virus pathogenicity in mice

scientific article

Role of the aryl hydrocarbon receptor in thymocyte emigration in vivo

scientific article

S100A9 deficiency alters adenosine-5'-triphosphate induced calcium signalling but does not generally interfere with calcium and zinc homeostasis in murine neutrophils

scientific article

S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model

scientific article published on 25 February 2014

S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity

scientific article (publication date: 15 April 2003)

Small molecule inhibitors of the c-Jun N-terminal kinase (JNK) possess antiviral activity against highly pathogenic avian and human pandemic influenza A viruses

scientific article

Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis

scientific article

The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structures in the Nucleus

scientific article published on 07 September 2021

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells

scientific article published on 9 May 2010

The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2.

scientific article

The calcium binding protein S100A9 is essential for pancreatic leukocyte infiltration and induces disruption of cell-cell contacts

scientific article published in August 2008

The gene encoding the myeloid-related protein 14 (MRP14), a calcium-binding protein expressed in granulocytes and monocytes, contains a potent enhancer element in the first intron

scientific article

The hetero-oligomeric complex of the S100A8/S100A9 protein is extremely protease resistant

scientific article published on 08 October 2007

The heterodimer of the Ca2+-binding proteins MRP8 and MRP14 binds to arachidonic acid

scientific article published on 01 May 1997

The mouse homologue of the HTLV-I tax responsive element binding protein TAXREB107 is a highly conserved gene which may regulate some basal cellular functions

scientific article published on April 1995

The myeloid expressed EF-hand proteins display a diverse pattern of lipid raft association

scientific article published on August 2004

The response of the novel pro-inflammatory molecules S100A8/A9 to exercise.

scientific article published in September 2006

Zinc binding reverses the calcium-induced arachidonic acid-binding capacity of the S100A8/A9 protein complex

scientific article published on 01 October 1999

List of works by Wolfgang Nacken

A homologue of the human MSS1 gene, a positive modulator of HIV-1 gene expression, is massively expressed in Xenopus oocytes

Absence of S100A12 in mouse: implications for RAGE-S100A12 interaction

Activation of c-jun N-terminal kinase upon influenza A virus (IAV) infection is independent of pathogen-related receptors but dependent on amino acid sequence variations of IAV NS1.

Analysis of the MRP8-MRP14 protein-protein interaction by the two-hybrid system suggests a prominent role of the C-terminal domain of S100 proteins in dimer formation

Biochemical characterization of the murine S100A9 (MRP14) protein suggests that it is functionally equivalent to its human counterpart despite its low degree of sequence homology

Computational searches for missing orthologs: the case of S100A12 in mice

Double-stranded RNA induces MMP-9 gene expression in HaCaT keratinocytes by tumor necrosis factor-α.

Double-stranded RNA induces S100 gene expression by a cycloheximide-sensitive factor

Expression of S100A8/A9 in HaCaT keratinocytes alters the rate of cell proliferation and differentiation

Expression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis

Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes.

HaCaT Keratinocytes Overexpressing the S100 Proteins S100A8 and S100A9 Show Increased NADPH Oxidase and NF-κB Activities

Identification of a novel HIV-1 TAR RNA bulge binding protein

Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

Interaction between S100A8/A9 and annexin A6 is involved in the calcium-induced cell surface exposition of S100A8/A9.

Interaction of S100A8/S100A9-arachidonic acid complexes with the scavenger receptor CD36 may facilitate fatty acid uptake by endothelial cells

Loss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitro

MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes

Members of the AAA-gene family are involved in early embryogenesis of vertebrates

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

Molecular analysis of the mouse S100A9 gene and evidence that the myeloid specific transcription factor C/EBPepsilon is not required for the regulation of the S100A9/A8 gene expression in neutrophils

Molecular characterisation of the genomic locus of the mouse MRP8 gene

Mrp-8 and -14 mediate CNS injury in focal cerebral ischemia

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

Myeloid-related protein (MRP)-8 from cervico-vaginal secretions activates HIV replication

Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis

Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans

PAR1 contributes to influenza A virus pathogenicity in mice

Role of the aryl hydrocarbon receptor in thymocyte emigration in vivo

S100A9 deficiency alters adenosine-5'-triphosphate induced calcium signalling but does not generally interfere with calcium and zinc homeostasis in murine neutrophils

S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model

S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity

Small molecule inhibitors of the c-Jun N-terminal kinase (JNK) possess antiviral activity against highly pathogenic avian and human pandemic influenza A viruses

Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis

The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structures in the Nucleus

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells

The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2.

The calcium binding protein S100A9 is essential for pancreatic leukocyte infiltration and induces disruption of cell-cell contacts

The gene encoding the myeloid-related protein 14 (MRP14), a calcium-binding protein expressed in granulocytes and monocytes, contains a potent enhancer element in the first intron

The hetero-oligomeric complex of the S100A8/S100A9 protein is extremely protease resistant

The heterodimer of the Ca2+-binding proteins MRP8 and MRP14 binds to arachidonic acid

The mouse homologue of the HTLV-I tax responsive element binding protein TAXREB107 is a highly conserved gene which may regulate some basal cellular functions

The myeloid expressed EF-hand proteins display a diverse pattern of lipid raft association

The response of the novel pro-inflammatory molecules S100A8/A9 to exercise.

Zinc binding reverses the calcium-induced arachidonic acid-binding capacity of the S100A8/A9 protein complex