List of works - Alan Serrels

A complex between FAK, RACK1, and PDE4D5 controls spreading initiation and cancer cell polarity

scientific article published on 20 May 2010

A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model

scientific article

Combined BCR-ABL inhibition with lentiviral-delivered shRNA and dasatinib augments induction of apoptosis in Philadelphia-positive cells

scientific article

Development of a fluorescence-based cellular apoptosis reporter

article

E-cadherin-integrin crosstalk in cancer invasion and metastasis

scientific article

Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy

scientific article published on 01 May 2019

FAK goes nuclear to control antitumor immunity-a new target in cancer immuno-therapy

scientific article

FAK to the rescue: activated stroma promotes a "safe haven" for BRAF-mutant melanoma cells by inducing FAK signaling.

scientific article

FAK-inhibition opens the door to checkpoint immunotherapy in Pancreatic Cancer

scientific article published on 21 February 2017

Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex

scientific article published on 26 August 2007

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion

scientific article published on 14 April 2021

High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy

scientific article published on 10 January 2018

IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks

scientific article published on 5 December 2017

Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib

scientific article published on 5 December 2006

Imaging drug uptake by bioorthogonal stimulated Raman scattering microscopy

scientific article published on 24 May 2017

In vivo imaging of the tumor and its associated microenvironment using combined CARS / 2-photon microscopy

scientific article published on January 2015

Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.

scientific article

Live cell in vitro and in vivo imaging applications: accelerating drug discovery

scientific article published on 4 April 2011

Multiphoton Microscopy for Visualizing Lipids in Tissue

scientific article

New approaches to intracellular drug imaging by stimulated Raman scattering microscopy

Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth

scientific article published on 14 August 2017

Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity

scientific article

Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: effects on E-cadherin dynamics

scientific article

Quantitative real-time imaging of molecular dynamics during cancer cell invasion and metastasis in vivo

scientific article published on 07 October 2009

Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development

scientific article published on 24 March 2009

Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue

scientific article (publication date: 2016)

Src/FAK-mediated regulation of E-cadherin as a mechanism for controlling collective cell movement: insights from in vivo imaging

scientific article published on July 2011

Stimulated Raman scattering microscopy: an emerging tool for drug discovery

scientific article

T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity

scientific article published on 21 January 2020

The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration

scientific article

The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells

scientific article

Two-color photoactivatable probe for selective tracking of proteins and cells

scientific article

Use of photoactivation and photobleaching to monitor the dynamic regulation of E-cadherin at the plasma membrane

scientific article published on October 2010

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source.

scientific article

p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism.

scientific article

List of works by Alan Serrels

A complex between FAK, RACK1, and PDE4D5 controls spreading initiation and cancer cell polarity

A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model

Combined BCR-ABL inhibition with lentiviral-delivered shRNA and dasatinib augments induction of apoptosis in Philadelphia-positive cells

Development of a fluorescence-based cellular apoptosis reporter

E-cadherin-integrin crosstalk in cancer invasion and metastasis

Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy

FAK goes nuclear to control antitumor immunity-a new target in cancer immuno-therapy

FAK to the rescue: activated stroma promotes a "safe haven" for BRAF-mutant melanoma cells by inducing FAK signaling.

FAK-inhibition opens the door to checkpoint immunotherapy in Pancreatic Cancer

Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion

High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy

IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks

Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib

Imaging drug uptake by bioorthogonal stimulated Raman scattering microscopy

In vivo imaging of the tumor and its associated microenvironment using combined CARS / 2-photon microscopy

Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.

Live cell in vitro and in vivo imaging applications: accelerating drug discovery

Multiphoton Microscopy for Visualizing Lipids in Tissue

New approaches to intracellular drug imaging by stimulated Raman scattering microscopy

Nuclear FAK and Runx1 Cooperate to Regulate IGFBP3, Cell-Cycle Progression, and Tumor Growth

Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity

Quantitative in vivo imaging of the effects of inhibiting integrin signaling via Src and FAK on cancer cell movement: effects on E-cadherin dynamics

Quantitative real-time imaging of molecular dynamics during cancer cell invasion and metastasis in vivo

Real-time study of E-cadherin and membrane dynamics in living animals: implications for disease modeling and drug development

Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue

Src/FAK-mediated regulation of E-cadherin as a mechanism for controlling collective cell movement: insights from in vivo imaging

Stimulated Raman scattering microscopy: an emerging tool for drug discovery

T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity

The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration

The role of focal adhesion kinase catalytic activity on the proliferation and migration of squamous cell carcinoma cells

Two-color photoactivatable probe for selective tracking of proteins and cells

Use of photoactivation and photobleaching to monitor the dynamic regulation of E-cadherin at the plasma membrane

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source.

p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism.