List of works - Joshua M Gorham

5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.

scientific article published on 10 February 2014

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

scientific article published on February 2016

Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis.

scientific article

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

scientific article

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.

scientific article published on 7 July 2015

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

scientific article

Cells and gene expression programs in the adult human heart

scientific article published on 05 April 2020

Cells of the adult human heart

scientific article published on 24 September 2020

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot

scientific article published on 13 July 2009

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease

scientific article published on 29 April 2020

Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation

scientific article published on 18 August 2021

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm

scientific article published on 15 October 2020

Glycogen storage diseases presenting as hypertrophic cardiomyopathy

scientific article published in January 2005

HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

scientific article

Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy

scientific article

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin

scientific article published on 01 January 2019

Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing

scientific article

Loss of RNA expression and allele-specific expression associated with congenital heart disease.

scientific article published on 27 September 2016

Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy

scientific article

Robust identification of mosaic variants in congenital heart disease

scientific article published on 7 February 2018

Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy

scientific article published on 8 April 2010

Single-Cell Resolution of Temporal Gene Expression during Heart Development

scientific article published on 9 November 2016

List of works by Joshua M Gorham

5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis.

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

Cells and gene expression programs in the adult human heart

Cells of the adult human heart

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease

Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm

Glycogen storage diseases presenting as hypertrophic cardiomyopathy

HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin

Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing

Loss of RNA expression and allele-specific expression associated with congenital heart disease.

Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy

Robust identification of mosaic variants in congenital heart disease

Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy

Single-Cell Resolution of Temporal Gene Expression during Heart Development