List of works - Hiroko Wakimoto

5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.

scientific article published on 10 February 2014

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

scientific article published on February 2016

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage

scientific article

Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy

scientific article

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

scientific article

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.

scientific article published on 7 July 2015

Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis

scientific article

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

scientific article

Cells and gene expression programs in the adult human heart

scientific article published on 05 April 2020

Cells of the adult human heart

scientific article published on 24 September 2020

De novo mutations in histone-modifying genes in congenital heart disease.

scientific article

Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy

scientific article

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin

scientific article published on 01 January 2019

IL-11 is a crucial determinant of cardiovascular fibrosis.

scientific article

Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.

scientific article

Loss of RNA expression and allele-specific expression associated with congenital heart disease.

scientific article published on 27 September 2016

Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma

scientific article published on 02 July 2019

Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors

scientific article published on 10 February 2009

Single-Cell Resolution of Temporal Gene Expression during Heart Development

scientific article published on 9 November 2016

List of works by Hiroko Wakimoto

5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage

Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.

Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter

Cells and gene expression programs in the adult human heart

Cells of the adult human heart

De novo mutations in histone-modifying genes in congenital heart disease.

Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin

IL-11 is a crucial determinant of cardiovascular fibrosis.

Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.

Loss of RNA expression and allele-specific expression associated with congenital heart disease.

Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma

Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors

Single-Cell Resolution of Temporal Gene Expression during Heart Development