List of works by William J. Murphy

'Unlicensed' natural killer cells dominate the response to cytomegalovirus infection

scientific article published on 28 February 2010

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts: National Harbor, MD, USA. 9-13 November 2016.

scientific article published on 8 December 2016

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion ⬇️

scientific article published on August 1, 1995

A possible new pathway in natural killer cell activation also reveals the difficulty in determining human NK cell function in cancer

article

Activated allogeneic NK cells as suppressors of alloreactive responses

scientific article published on 01 March 2010

Activated natural killer cells and interleukin-2 promote granulocytic and megakaryocytic reconstitution after syngeneic bone marrow transplantation in mice

scientific article published on October 1993

Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax

scientific article published on 01 July 2002

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

scientific article

Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.

scientific article

Adoptive immunotherapy involving recombinant human M-CSF and R24 anti-melanoma antibody induces human T-cell infiltration into human melanoma xenografts

scientific article published on September 1996

Advances in graft-versus-host disease biology and therapy

scientific article

Advantages and clinical applications of natural killer cells in cancer immunotherapy

scientific article

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

scientific article published on 30 September 2013

Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration

scientific article

Alterations in cancer stem-cell marker CD44 expression predict oncologic outcome in soft-tissue sarcomas

scientific article published on 22 December 2017

Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease

scientific article

An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease

scientific article published in March 2004

An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells

scientific article

Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas

scientific article published on 01 November 2020

Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma

scientific article

Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation.

scientific article published in January 2001

Antigen Specific Memory T Cells and Their Putative Need for the Generation of Sustained Anti-Tumor Responses ⬇️

scientific article published on January 1, 2010

Antigen-specific versus antigen-nonspecific immunotherapeutic approaches for human melanoma: the need for integration for optimal efficacy?

scientific article published on October 2011

Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts

scientific article

Antitumor effects of nonconjugated murine Lym-2 and human-mouse chimeric CLL-1 monoclonal antibodies against various human lymphoma cell lines in vitro and in vivo

scientific article published on 01 October 1997

Association of macrophage and lymphocyte infiltration with outcome in canine osteosarcoma

scientific article published on 19 September 2018

Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo

scientific article published on 01 May 2001

Autoimmune T cells lured to a FASL web of death by MSCs

scientific article published in May 2012

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

scientific article published on 26 March 2015

Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells.

scientific article

Beta chemokines costimulate lymphocyte cytolysis, proliferation, and lymphokine production

scientific article published on January 1996

Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies.

scientific article published on 15 March 2016

Blocking indolamine 2,3 dioxygenase mediated rebound immune suppression improves systemic anti-tumor effects of radio-immunotherapy.

scientific article published on 4 November 2015

Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer

scientific article published on 21 February 2020

Blood stem cell transplantation in older patients

scientific article published in December 2009

Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD).

scientific article

Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells

scientific article published on 14 January 2019

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity

scientific article

Bortezomib sensitizes human glioblastoma stem cells to adoptive natural killer cell cytotoxicity

scientific article published on 4 November 2015

Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help

scientific article

Bystander memory CD8 T cell proliferation after anti-CD40/IL-2 treatment is independent of CD4 T cells

scientific article published on 7 November 2013

CD16 cross-linking blocks rearrangement of the TCR beta locus and development of alpha beta T cells and induces development of NK cells from thymic progenitors.

scientific article published in October 1998

CD40 stimulation promotes human secondary immunoglobulin responses in HuPBL-SCID chimeras

scientific article published on 01 January 1999

CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus

scientific article published on July 2008

Canine cancer immunotherapy studies: linking mouse and human

scientific article

Cellular and molecular studies in the treatment of murine renal cancer

scientific article published on February 1995

Chemokine-induced human lymphocyte infiltration and engraftment in huPBL-SCID mice

scientific article published on 01 January 1997

Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro

scientific article published on 01 March 1996

Chemokines and T lymphocyte activation: II. Facilitation of human T cell trafficking in severe combined immunodeficiency mice.

scientific article

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

scientific article

Combination radioimmunotherapy with adoptive NK transfer targets cancer stem cells in canine models of bone and soft tissue sarcoma.

scientific article published on 4 November 2015

Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses

scientific article published on October 2008

Combined radiotherapy and immunotherapy using CPG oligodeoxynucleotides and indolamine 2,3 dioxygenase (IDO) blockade.

scientific article published on 7 November 2013

Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy

scientific article

Comparative Immunogenomics of Canine Natural Killer Cells as Immunotherapy Target

scientific article published on 14 September 2021

Contrasting effects of anti-Ly49A due to MHC class I cis binding on NK cell-mediated allogeneic bone marrow cell resistance

scientific article published on 10 June 2013

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

scientific article published on 01 November 2019

Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens

scientific article published on 01 May 2000

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy

scientific article published on 17 January 2012

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

scientific article published on 18 March 2019

Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation

scientific article published on 6 June 2008

Differential effects of growth hormone and prolactin on murine T cell development and function

scientific article

Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity

scientific article published on 16 June 2005

Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice

scientific article

Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets

scientific article

Differential expression of the Ly49G(B6), but not the Ly49G(BALB), receptor isoform during natural killer cell reconstitution after hematopoietic stem cell transplantation.

scientific article published on 31 July 2013

Differential in vitro and in vivo antitumor effects mediated by anti-CD40 and anti-CD20 monoclonal antibodies against human B-cell lymphomas

scientific article published on 01 March 1996

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

scientific article

Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

scientific article published on 20 April 2020

Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides

scientific article published on January 2004

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation.

scientific article published on 7 June 2018

Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans

scientific article published on 9 November 2011

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

scientific article published on 03 October 2019

Donor-type activated natural killer cells promote marrow engraftment and B cell development during allogeneic bone marrow transplantation ⬇️

scientific article published on May 1, 1992

Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells

scientific article published on 14 September 2020

Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new.

scientific article

Effects of CD40 stimulation in the prevention of human EBV-lymphomagenesis

scientific article published on January 1997

Effects of cancer immunotherapy regimens on primary vs. secondary immune responses and the potential impact on long-term antitumor responses.

scientific article published on January 2009

Effects of growth hormone and prolactin immune development and function ⬇️

scientific article published on January 1, 1995

Effects of growth hormone and prolactin on hematopoiesis

scientific article

Effects of housing on the thymic deficiency in dwarf mice and its reversal by growth hormone administration ⬇️

scientific article published on November 1, 2003

Effects of organ-specific loss of insulin-like growth factor-I production on murine hematopoiesis

scientific article published on 01 January 2004

Effects of prolactin on hematopoiesis

scientific article

Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency.

scientific article published in April 1993

Engraftment of SCID mice by human bone marrow hematopoietic cells cultured in vitro: an in vivo model for human gene transfer.

scientific article published in October 1995

Engraftment of ex vivo expanded and cycling human cord blood hematopoietic progenitor cells in SCID mice

scientific article published on 01 June 1998

Enhanced natural killer cell targeting of cancer stem cells using Cetuximab

scientific article published on 6 November 2014

Enhanced targeting of stem-like solid tumor cells with radiation and natural killer cells

scientific article

Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells

scientific article published on 01 June 2001

Epstein-Barr virus-induced human B-cell lymphoma arising in HuPBL-SCID chimeric mice: characterization and the role of CD40 stimulation in their treatment and prevention

scientific article published in January 1995

Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease.

scientific article published on March 2009

Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34(+)/CD38(-) early progenitors cultured over human MSCs as a feeder layer

scientific article published on 01 January 2002

Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion

scientific article published on 21 March 2022

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.

scientific article

Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation

scientific article published on 01 March 2001

Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo model for genetically transferred chemoprotection.

scientific article

Growth hormone as an immunomodulating therapeutic agent

scientific article published on 01 May 2000

Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine ⬇️

scientific article published on September 15, 1992

Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment

scientific article

Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta ⬇️

scientific article published on June 1, 1995

Hematopoietic Growth promoting Effects of Natural Killer Cells in Mice in responce to In Vivo Administration of Human Interleukin-2 ⬇️

scientific article published on 01 August 1992

Hematopoietic progenitor cell regulation by CD4+CD25+ T cells

scientific article

High fluence light emitting diode-generated red light modulates characteristics associated with skin fibrosis.

scientific article published on 13 May 2016

Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions

scientific article published on 01 November 2000

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

scientific article published on 12 September 2013

Human RANTES induces the migration of human T lymphocytes into the peripheral tissues of mice with severe combined immune deficiency

scientific article published on 01 August 1994

Human growth hormone promotes engraftment of murine or human T cells in severe combined immunodeficient mice ⬇️

scientific article published on May 15, 1992

Human insulin-like growth factor I exerts hematopoietic growth-promoting effects after in vivo administration

scientific article published on 01 December 1994

Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice

scientific article

Human-mouse lymphoid chimeras: host-vs.-graft and graft-vs.-host reactions

scientific article published on June 1, 1992

Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation

scientific article

IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy

scientific article

IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation.

scientific article

IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

scientific article published on 27 February 2003

IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation

scientific article published on 29 October 2020

IL-8-Induced T-Lymphocyte Migration: Direct as Well as Indirect Mechanisms

scientific article published on 01 August 1996

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

scientific article

Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils

scientific article

Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils

scientific article

Immune targeting of cancer stem cells in gastrointestinal oncology

scientific article

Immunobiology of allogeneic hematopoietic stem cell transplantation

scientific article published on January 2007

Immunobiology of natural killer cells and bone marrow transplantation: merging of basic and preclinical studies

scientific article

Immunoediting and antigen loss: overcoming the achilles heel of immunotherapy with antigen non-specific therapies

scientific article published on 26 July 2013

Immunologic and hematologic effects of neuroendocrine hormones. Studies on DW/J dwarf mice ⬇️

scientific article published on June 15, 1992

Immunologic and hematopoietic effects of CD40 stimulation after syngeneic bone marrow transplantation in mice

scientific article published on February 1997

Immunologic and hematopoietic effects of recombinant human prolactin after syngeneic bone marrow transplantation in mice

scientific article published in July 2003

Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease

scientific article published on 01 September 2008

Immunomodulation with CD40 stimulation and interleukin-2 protects mice from disseminated cryptococcosis

scientific article

Immunotherapy following hematopoietic stem cell transplantation: potential for synergistic effects

scientific article

Impact of aging in cancer immunotherapy: The importance of using accurate preclinical models

scientific article published on 9 December 2013

In vivo antitumor effects of unconjugated CD30 monoclonal antibodies on human anaplastic large-cell lymphoma xenografts ⬇️

scientific article published on November 15, 1995

In vivo hydrodynamic delivery of cDNA encoding IL-2: rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells

scientific article published on 01 July 2005

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

scientific article

Increased antitumor effects using IL-2 with anti-TGF-β reveals competition between mouse NK and CD8 T cells.

scientific article

Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens

scientific article

Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta

scientific article published on 01 October 1999

Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID)

scientific article published on 01 August 1994

Induction of alloantigen-specific T cell tolerance through the treatment of human T lymphocytes with wortmannin

Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation

scientific article published on 01 August 2000

Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function.

scientific article published on January 2014

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

scientific article published on 27 June 2013

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib

scientific article

Inhibition of human B-cell lymphoma growth by CD40 stimulation

scientific article published on 01 May 1994

Inhibition of human breast carcinoma growth by a soluble recombinant human CD40 ligand

scientific article published on 01 May 1999

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

scientific article published on 01 January 2020

Interleukin-2-activated natural killer cells can support hematopoiesis in vitro and promote marrow engraftment in vivo ⬇️

scientific article published on August 1, 1992

Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury

scientific article published on 01 December 2000

Lack of correlation between an assay used to determine early marrow allograft rejection and long-term chimerism after murine allogeneic bone marrow transplantation: effects of marrow dose

scientific article published on 01 April 2005

Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy

scientific article published on 30 September 2015

Leveraging natural killer cells for cancer immunotherapy

scientific article published in May 2017

Licensing delineates helper and effector NK cell subsets during viral infection

scientific article

Ly-49 G2+ NK cells are responsible for mediating the rejection of H-2b bone marrow allografts in mice.

scientific article published in December 1996

Ly-49 receptor expression and functional analysis in multiple mouse strains

scientific article published on 01 September 1999

Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy.

scientific article

Mechanical disruption of tumors by iron particles and magnetic field application results in increased anti-tumor immune responses

scientific article

Metastatic immune infiltrates correlate with those of the primary tumour in canine osteosarcoma

scientific article published on 08 April 2019

Minimal PD-1 expression in mouse and human NK cells under diverse conditions

scientific article published on 05 March 2020

Models to Study NK Cell Biology and Possible Clinical Application

scientific article published on 3 August 2015

Monoclonal antibody therapies targeting immune checkpoints induce fatal anaphylactic reactions in a murine model of breast cancer.

scientific article published on 6 November 2014

Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes

scientific article published on March 1995

Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC

scientific article

Mouse NK cell-mediated rejection of bone marrow allografts exhibits patterns consistent with Ly49 subset licensing

scientific article published on 19 December 2011

Mouse host unlicensed NK cells promote donor allogeneic bone marrow engraftment.

scientific article published on 6 January 2016

Moving forward to address key unanswered questions on targeting PD-1/PD-L1 in cancer: limitations in preclinical models and the need to incorporate human modifying factors

scientific article published on 07 November 2019

Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs

article

Murine natural killer cell licensing and regulation by T regulatory cells in viral responses

scientific article published on 15 April 2013

NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic

scientific article published on 10 February 2010

NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

scientific article published on 11 September 2015

NK Cells in the Regulation of Hematopoiesis

scientific article published on April 1996

NK cell subsets in the regulation of murine hematopoiesis. I. 5E6+ NK cells promote hematopoietic growth in H-2d strain mice.

scientific article published on September 1995

NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution

scientific article

NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade

scientific article published on 31 July 2003

Natural killer cell immunotherapy to target stem-like tumor cells

scientific article published on 19 April 2016

Natural killer cell subsets differentially reject embryonic stem cells based on licensing

scientific article

Natural killer cells activated with interleukin 2 in vitro can be adoptively transferred and mediate hematopoietic histocompatibility-1 antigen-specific bone marrow rejection in vivo

scientific article

Natural killer cells and bone marrow transplantation

scientific article

Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network

scientific article published on 4 March 2008

New strategies for preventing graft-versus-host disease

scientific article

Novel tumor necrosis factor-knockout mice that lack Peyer's patches

scientific article published on 01 May 2005

Obesity and cancer immunotherapy toxicity

scientific article published on January 2015

Obesity as an immune-modifying factor in cancer immunotherapy

scientific article published on 15 May 2018

Obesity induced T cell dysfunction and implications for cancer immunotherapy

scientific article published on 11 April 2018

Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation

scientific article published on 01 November 2020

Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning

scientific article published on 01 January 2000

Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity

scientific article published on 28 July 2015

PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment

scientific article published on 29 October 2020

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.

scientific article published on 12 November 2018

Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation

scientific article published on 13 September 2005

Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients

scientific article published in May 1998

Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.

scientific article

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

scientific article

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

scientific article published on 13 June 2016

Prolactin exerts hematopoietic growth-promoting effects in vivo and partially counteracts myelosuppression by azidothymidine

scientific article

Proteasome inhibition and allogeneic hematopoietic stem cell transplantation: a review

scientific article

Protection from direct cerebral cryptococcus infection by interferon-gamma-dependent activation of microglial cells

scientific article

Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial.

scientific article published on 19 December 2017

Recombinant human growth hormone promotes hematopoietic reconstitution after syngeneic bone marrow transplantation in mice

scientific article published in January 1998

Recombinant human growth hormone promotes human lymphocyte engraftment in immunodeficient mice and results in an increased incidence of human Epstein Barr virus-induced B-cell lymphoma

scientific article published on December 1, 1992

Regulation of murine NK cell exhaustion through the activation of the DNA damage repair pathway

scientific article published on 18 June 2019

Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/αCD40 therapy

scientific article

Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy

scientific article published on March 2008

Rejection of bone marrow cells by irradiated mice: NK and T cells recognize different antigens

scientific article published on 01 December 1987

Rejuvenation of the aging thymus: growth hormone-mediated and ghrelin-mediated signaling pathways

scientific article

Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer

scientific article published on 12 August 2015

Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses

scientific article published on 24 September 2020

Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Skin Fibroblast Migration.

scientific article published on 21 October 2015

Role for CD40-CD40 ligand interactions in the immune response to solid tumours

scientific article published on June 2000

Role of interleukin-12 in acute graft-versus-host disease(1)

scientific article published on 01 February 2001

Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo

scientific article published in December 1992

Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition

scientific article

Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes

scientific article

Small-molecule BCL6 inhibitor effectively treats mice with non-sclerodermatous chronic graft-versus-host disease

article

Specificity may be overrated in cancer immunotherapy: Getting to know the nonspecific side of memory T Cells

scientific article published on October 2012

Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site

scientific article published on 22 April 2018

Stimulating Innate Immunity to Enhance Radiation Therapy-Induced Tumor Control

scientific article

Stimulation through CD40 on mouse and human renal cell carcinomas triggers cytokine production, leukocyte recruitment, and antitumor responses that can be independent of host CD40 expression

scientific article published on June 2006

Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment

scientific article

Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation

scientific article published on May 1998

Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells

scholarly article

Synergistic anti-tumor responses after administration of agonistic antibodies to CD40 and IL-2: coordination of dendritic and CD8+ cell responses

scientific article published on 01 March 2003

Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts.

scientific article

T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo

scientific article published on April 1996

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

scientific article published on 09 July 2008

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.

scientific article published on 16 March 2016

Targeting Cancer Stem Cells with Natural Killer Cell Immunotherapy

scientific article published on 14 December 2016

Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

scientific article published on 19 March 2019

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

scientific article published on 7 April 2015

The Surprisingly Positive Association Between Obesity and Cancer Immunotherapy Efficacy

scientific article published on 01 April 2019

The authors' reply

scientific article published in September 2014

The complicated effects of  obesity on cancer and immunotherapy

scientific article published on 01 January 2019

The diverse role of chemokines in tumor progression: prospects for intervention (Review).

scientific article

The huPBL-SCID mouse as a means to examine human immune function in vivo

scientific article published on August 1996

The immunobiology of natural killer cells and bone marrow allograft rejection

scientific article

The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific IG production in mice

scientific article

The potential role of NK cells in the separation of graft‐versus‐tumor effects from graft‐versus‐host disease after allogeneic bone marrow transplantation ⬇️

scientific article published on June 1, 1997

The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.

scientific article published on 13 March 2003

The role of antigen-specific and non-specific immunotherapy in the treatment of cancer

scientific article published on 26 June 2012

The role of growth hormone in T-cell development and reconstitution

scientific article

The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality

scientific article

The triterpenoid CDDO-Me delays murine acute graft-versus-host disease with the preservation of graft-versus-tumor effects after allogeneic bone marrow transplantation

scientific article

The triterpenoid CDDO-Me promotes hematopoietic progenitor expansion and myelopoiesis in mice

scientific article

Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels

scientific article

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

scientific article published on 6 July 2016

Thymic emigrants isolated by a new method possess unique phenotypic and functional properties

article published in 2001

Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody

scientific article published on 29 April 2008

Treatment of chronic graft-versus-host disease with bortezomib

scientific article

Tumor regression by anti-CD40 and interleukin-2: role of CD40 in hematopoietic cells and organ-specific effects

scientific article published on August 2004

Use of neuroendocrine hormones to promote reconstitution after bone marrow transplantation

scientific article published on 01 January 1999

Use of systemic proteasome inhibition as an immune-modulating agent in disease

scientific article published on March 2007

mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia

scholarly article

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