List of works by Hideki Hasegawa

130 Reinhard Kurth Honorary Lecture HTLV-I and Adult T Cell Leukemia/Lymphoma (ATLL): Cellular and Molecular Basis of Transformation.

scientific article

2016 International meeting of the Global Virus Network

scientific article (publication date: June 2017)

2017 international meeting of the Global Virus Network

scientific article published on 5 February 2018

2019 meeting of the global virus network

scientific article published on 04 November 2019

A Glycolipid Adjuvant, 7DW8-5, Enhances the Protective Immune Response to the Current Split Influenza Vaccine in Mice

scientific article published on 18 September 2019

A Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected via Respiratory Droplets

scientific article published on 17 October 2017

A Sialylated Voltage-Dependent Ca Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells

scientific article published on 17 May 2018

A Single Vaccination of Nonhuman Primates with Highly Attenuated Smallpox Vaccine, LC16m8, Provides Long-term Protection against Monkeypox

scientific article published on 22 December 2016

A mutant H3N2 influenza virus uses an alternative activation mechanism in TMPRSS2 knockout mice by loss of an oligosaccharide in the hemagglutinin stalk region

scientific article

A novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes and provides extended survival period.

scientific article published on 7 January 2014

A novel function of the N-terminal domain of PA in assembly of influenza A virus RNA polymerase

scientific article published on 6 October 2011

Acute Liver Failure Associated with Influenza A Virus Infection: an Autopsy Case Report

scientific article published on 31 May 2019

Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus

Adenovirus Type 7 Pneumonia in Children Who Died from Measles-Associated Pneumonia, Hanoi, Vietnam, 2014

scientific article published on April 2016

Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derived chemotaxin 2 deficient mice.

scientific article published on 13 October 2017

An assessment of real-time RT-PCR kits for SARS-CoV-2 detection

scientific article published on 30 April 2020

An attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection

scientific article

An autopsy case of Balamuthia mandrillaris amoebic encephalitis, a rare emerging infectious disease, with a brief review of the cases reported in Japan

scientific article

An outbreak of histoplasmosis among healthy young Japanese women after traveling to Southeast Asia

scientific article published in March 2010

Analysis of bronchoalveolar lavage fluid in a mouse model of bronchial asthma and H1N1 2009 infection

scientific article

Application of HTLV-1 tax transgenic mice for therapeutic intervention.

scientific article

Assessment of outer membrane vesicles of periodontopathic bacterium Porphyromonas gingivalis as possible mucosal immunogen

scientific article published on 22 July 2016

Association of lymph-node antigens with lower Gag-specific central-memory and higher Env-specific effector-memory CD8(+) T-cell frequencies in a macaque AIDS model

scientific article published on 25 July 2016

Association of major histocompatibility complex class I haplotypes with disease progression after simian immunodeficiency virus challenge in burmese rhesus macaques.

scientific article

BCL-6-positive Human Herpesvirus 8-associated Solid Lymphoma Arising from Liver and Spleen as Multiple Nodular Lesions

scientific article published on 01 October 2004

Binding and dissociation of human topoisomerase I with hairpin-loop RNAs: implications for the regulation of HIV-1 replication

scientific article

Candidatus Mycoplasma haemohominis in Human, Japan

scientific article published on 01 January 2020

Canine distemper virus associated with a lethal outbreak in monkeys can readily adapt to use human receptors

scientific article published on 17 April 2013

Characterization of H7N9 influenza A viruses isolated from humans.

scientific article

Characterization of a Feline Influenza A(H7N2) Virus

scientific article published in January 2018

Characterization of neutralizing antibodies in adults after intranasal vaccination with an inactivated influenza vaccine

scientific article published on 01 February 2012

Characterization of quasispecies of pandemic 2009 influenza A virus (A/H1N1/2009) by de novo sequencing using a next-generation DNA sequencer.

scientific article

Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential.

scientific article

Classification of AIDS-related lymphoma cases between 1987 and 2012 in Japan based on the WHO classification of lymphomas, fourth edition.

scientific article published on 10 January 2014

Combatting infectious diseases; nanotechnology as a platform for rational vaccine design

scientific article published on 23 May 2014

Combination Therapy with Neuraminidase and Polymerase Inhibitors in Nude Mice Infected with Influenza Virus

scientific article published on 25 November 2017

Comparative proteomic analysis of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma

Comparison of acellular pertussis-based combination vaccines by Japanese control tests for toxicities and laboratory models for local reaction

scientific article published on 31 January 2009

Conserved sequences of BART and BHRF regions encoding viral microRNAs in Epstein-Barr virus-associated lymphoma.

scientific article

Corrigendum to: Environmental Sampling for Severe Acute Respiratory Syndrome Coronavirus 2 During a COVID-19 Outbreak on the Diamond Princess Cruise Ship

scientific article published on 09 September 2020

Covalent bonded Gag multimers in human immunodeficiency virus type-1 particles

scientific article

CpG ODN G9.1 as a novel nasal ODN adjuvant elicits complete protection from influenza virus infection without causing inflammatory immune responses

scientific article published on 22 July 2019

Cross-protection against H5N1 influenza virus infection is afforded by intranasal inoculation with seasonal trivalent inactivated influenza vaccine.

scientific article

Cross-protective immunity against influenza virus infections induced by intranasal vaccination together with a TLR3-mucosal adjuvant

scientific article

Cross-reactive antigenicity of nucleoproteins of lyssaviruses recognized by a monospecific antirabies virus nucleoprotein antiserum on paraffin sections of formalin-fixed tissues

scientific article published in August 2003

Cutaneous histopathology of the tick-bite region in severe fever with thrombocytopenia syndrome

scientific article published on 01 April 2019

Cytokine and growth factor expression by HTLV-1 Lck-tax transgenic cells in SCID mice.

scientific article published in May 2010

Deep-Sequence Identification and Role in Virus Replication of a JC Virus Quasispecies in Patients with Progressive Multifocal Leukoencephalopathy.

scientific article published on 19 October 2016

Detection of a peramivir-resistant influenza B/Yamagata-lineage virus imported from Indonesia in Aichi, Japan, March 2019

scientific article published on 29 May 2020

Detection of trichodysplasia spinulosa-associated polyomavirus in a fatal case of myocarditis in a seven-month-old girl

scientific article

Development of a mucosal vaccine for influenza viruses: preparation for a potential influenza pandemic.

scientific article

Development of a new real-time PCR system for simultaneous detection of bacteria and fungi in pathological samples

scientific article

Development of mucosal adjuvants for intranasal vaccine for H5N1 influenza viruses

scientific article

Development of oligomannose-coated liposome-based nasal vaccine against human parainfluenza virus type 3.

scientific article

Diagnosis and assessment of monkeypox virus (MPXV) infection by quantitative PCR assay: differentiation of Congo Basin and West African MPXV strains

scientific article published in March 2008

Dicer and positive charge of proteins decrease the stability of RNA containing the AU-rich element of GM-CSF.

scientific article published on 20 December 2005

Differential localization of neurons susceptible to enterovirus 71 and poliovirus type 1 in the central nervous system of cynomolgus monkeys after intravenous inoculation

scientific article published in October 2004

Distribution of PrP(Sc) in cattle with bovine spongiform encephalopathy slaughtered at abattoirs in Japan

scientific article

Double-Stranded Structure of the Polyinosinic-Polycytidylic Acid Molecule to Elicit TLR3 Signaling and Adjuvant Activity in Murine Intranasal A(H1N1)pdm09 Influenza Vaccination

scientific article published on 22 June 2020

Early mortality following intracerebral infection with the Oshima strain of tick-borne encephalitis virus in a mouse model

scientific article published on 9 December 2009

Effects of Toll-like receptor stimulation on eosinophilic infiltration in lungs of BALB/c mice immunized with UV-inactivated severe acute respiratory syndrome-related coronavirus vaccine

scientific article

Effects of the number of amino acid residues in the signal segment upstream or downstream of the NS2B-3 cleavage site on production and secretion of prM/M-E virus-like particles of West Nile virus

scientific article

Efficacy of T-705 (Favipiravir) in the Treatment of Infections with Lethal Severe Fever with Thrombocytopenia Syndrome Virus

scientific article

Emergence of Oseltamivir-Resistant H7N9 Influenza Viruses in Immunosuppressed Cynomolgus Macaques

scientific article published on September 2017

Environmental sampling for severe acute respiratory syndrome coronavirus 2 during COVID-19 outbreak in the Diamond Princess cruise ship

scientific article published on 21 July 2020

Establishing and characterizing a new primary effusion lymphoma cell line harboring Kaposi's sarcoma-associated herpesvirus.

scientific article published on 17 August 2016

Establishment of a panel of in-house polyclonal antibodies for the diagnosis of enterovirus infections

scientific article published on 28 September 2014

Estimation of the effective doses of nasal-inactivated influenza vaccine in humans from mouse-model experiments

scientific article published on January 2010

Evaluation of Vero-cell-derived simian endogenous retrovirus infection in humans by detection of viral genome in clinicopathological samples and commercialized vaccines and by serology of Japanese general population

scientific article published on 22 April 2016

Evaluation of the effectiveness and safety of chitosan derivatives as adjuvants for intranasal vaccines

scientific article published on 19 March 2013

Evidence for human herpesvirus-6B infection of regulatory T-cells in acute systemic lymphadenitis in an immunocompetent adult with the drug reaction with eosinophilia and systemic symptoms syndrome: a case report

scientific article published on 16 September 2014

Excessive cytokine response to rapid proliferation of highly pathogenic avian influenza viruses leads to fatal systemic capillary leakage in chickens

scientific article

Experimental infection of Cynomolgus Macaques with highly pathogenic H5N1 influenza virus through the aerosol route.

scientific article

Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies

scientific article published on 28 August 2019

Frequent detection of Merkel cell polyomavirus DNA in sera of HIV-1-positive patients

scientific article published on 13 March 2013

Fumagillin, a potent angiogenesis inhibitor, induces Kaposi sarcoma-associated herpesvirus replication in primary effusion lymphoma cells.

scientific article

Functional Analysis of Trichodysplasia Spinulosa-Associated Polyomavirus-Encoded Large T Antigen

scientific article published on 29 November 2019

Functional analysis of an alpha-helical antimicrobial peptide derived from a novel mouse defensin-like gene.

scientific article published on 14 July 2010

Functional and structural characteristics of secretory IgA antibodies elicited by mucosal vaccines against influenza virus

scientific article published on 3 August 2017

Fungus-Derived Neoechinulin B as a Novel Antagonist of Liver X Receptor, Identified by Chemical Genetics Using a Hepatitis C Virus Cell Culture System

scientific article

Gold nanoparticles as a vaccine platform: influence of size and shape on immunological responses in vitro and in vivo

scientific article published on 16 May 2013

Gold nanoparticle‐adjuvanted S protein induces a strong antigen‐specific IgG response against severe acute respiratory syndrome‐related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lung

scientific article published on 18 November 2019

Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak

scientific article (preprint)

Haplotype networks of SARS-CoV-2 infections in the Diamond Princess cruise ship outbreak

scientific article published on 28 July 2020

Herpes simplex virus 1 VP22 regulates translocation of multiple viral and cellular proteins and promotes neurovirulence

scientific article

High diversity of HHV-8 molecular subtypes in the Amazon region of Brazil: evidence of an ancient human infection.

scientific article

High expression of JC polyomavirus-encoded microRNAs in progressive multifocal leukoencephalopathy tissues and its repressive role in virus replication

scientific article published on 23 April 2020

Highly attenuated vaccinia virus DIs as a potential SARS vaccine

scientific article published in January 2006

Highly frequent mutations in negative regulators of multiple virulence genes in group A streptococcal toxic shock syndrome isolates

scientific article

Histopathological Findings of Lung with A/H1N1pdm09 Infection-Associated Acute Respiratory Distress Syndrome in the Post-Pandemic Season

scientific article

Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection

scientific article

Host Adaptation and the Alteration of Viral Properties of the First Influenza A/H1N1pdm09 Virus Isolated in Japan

scientific article

Human immune responses elicited by an intranasal inactivated H5 influenza vaccine

scientific article published on 20 January 2020

Human topoisomerase I promotes HIV-1 proviral DNA synthesis: implications for the species specificity and cellular tropism of HIV-1 infection.

scientific article

Human-to-Human Transmission of Influenza A(H3N2) Virus with Reduced Susceptibility to Baloxavir, Japan, February 2019

scientific article published on 17 November 2019

Identification and molecular characterization of a new nonsegmented double-stranded RNA virus isolated from Culex mosquitoes in Japan ⬇️

scientific article published on September 25, 2010

Identification of Mouse and Human Antibody Repertoires by Next-Generation Sequencing

scientific article published on 15 March 2019

Identification of a varicella-zoster virus replication inhibitor that blocks capsid assembly by interacting with the floor domain of the major capsid protein.

scientific article

Identification of cancer stem cells in a Tax-transgenic (Tax-Tg) mouse model of adult T-cell leukemia/lymphoma.

scientific article published on 7 July 2009

IgA polymerization contributes to efficient virus neutralization on human upper respiratory mucosa after intranasal inactivated influenza vaccine administration

scientific article published on 9 February 2018

IgA tetramerization improves target breadth but not peak potency of functionality of anti-influenza virus broadly neutralizing antibody

scientific article published on 03 January 2019

Immune reconstitution inflammatory syndrome associated with Kaposi's sarcoma: successful treatment with interferon-alpha

scientific article

Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses

scientific article published on 08 November 2019

Impacts of allergic airway inflammation on lung pathology in a mouse model of influenza A virus infection

scientific article

Induction of cross-protective immunity against influenza A virus H5N1 by an intranasal vaccine with extracts of mushroom mycelia

scientific article

Induction of lung CD8+ T cell responses by consecutive inoculations of a poly(I:C) influenza vaccine.

scientific article

Induction of protective immunity against severe acute respiratory syndrome coronavirus (SARS-CoV) infection using highly attenuated recombinant vaccinia virus DIs.

scientific article published on 6 May 2006

Inefficient Tax-specific T-cell responses in mice after syngeneic transplantation with tax-transgenic mouse-derived adult T-cell leukemia cells

scientific article published on 31 January 2020

Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets

scientific article published on 25 November 2019

Influenza A(H1N1)pdm09 virus exhibiting reduced susceptibility to baloxavir due to a PA E23K substitution detected from a child without baloxavir treatment

scientific article published on 20 June 2020

Inhibition of the SDF-1alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice.

scientific article

Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus

scientific article published on 19 February 2005

Innate sensors of influenza virus: clues to developing better intranasal vaccines

scientific article

Integrating genotypes and phenotypes improves long-term forecasts of seasonal influenza A/H3N2 evolution

scientific article published on 02 September 2020

Interleukin-6-dependent growth in a newly established plasmablastic lymphoma cell line and its therapeutic targets

scientific article published on 31 August 2017

Intracerebral inoculation of mouse-passaged Saffold virus type 3 affects cerebellar development in neonatal mice

scientific article published on 31 August 2016

Intranasal Administration of Whole Inactivated Influenza Virus Vaccine as a Promising Influenza Vaccine Candidate

scientific article published on 26 June 2017

Intranasal Inactivated Influenza Vaccines: a Reasonable Approach to Improve the Efficacy of Influenza Vaccine?

scientific article published on January 2016

Intranasal administration of adjuvant-combined recombinant influenza virus HA vaccine protects mice from the lethal H5N1 virus infection

scientific article published on 28 August 2006

Intranasal administration of adjuvant‐combined vaccine protects monkeys from challenge with the highly pathogenic influenza A H5N1 virus ⬇️

scientific article published on October 1, 2010

Intranasal immunization with H5N1 vaccine plus Poly I:Poly C12U, a Toll-like receptor agonist, protects mice against homologous and heterologous virus challenge.

scientific article published in July 2007

Intranasal inactivated influenza vaccines for the prevention of seasonal influenza epidemics

scientific article published on 27 August 2018

Intranasal vaccination with HBs and HBc protein combined with carboxyl vinyl polymer induces strong neutralizing antibody, anti-HBs IgA, and IFNG response

scientific article published on 30 September 2019

Intranasal vaccination with an inactivated whole influenza virus vaccine induces strong antibody responses in serum and nasal mucus of healthy adults

scientific article published on 27 June 2013

Knowledge Obtained from an Elderly Case of Japanese Encephalitis

scientific article published on September 2016

LC16m8, a highly attenuated vaccinia virus vaccine lacking expression of the membrane protein B5R, protects monkeys from monkeypox

scientific article

Lethal canine distemper virus outbreak in cynomolgus monkeys in Japan in 2008.

scientific article published on 7 November 2012

Loop-mediated isothermal amplification-based diagnostic assay for monkeypox virus infections

scientific article published in June 2009

Mechanism of drug resistance of hemagglutinin of influenza virus and potent scaffolds inhibiting its function

scientific article

Mobile and accurate detection system for infection by the 2009 pandemic influenza A (H1N1) virus with a pocket-warmer reverse-transcriptase loop-mediated isothermal amplification.

scientific article

Monoclonal antibody and siRNAs for topoisomerase I suppress telomerase activity.

scientific article published in February 2009

Mortality following peripheral infection with tick-borne encephalitis virus results from a combination of central nervous system pathology, systemic inflammatory and stress responses

scientific article published on 24 May 2009

Mouse LIMR3/CD300f is a negative regulator of the antimicrobial activity of neutrophils

scientific article published in Scientific Reports

Mouse-passaged severe acute respiratory syndrome-associated coronavirus leads to lethal pulmonary edema and diffuse alveolar damage in adult but not young mice

scientific article published on 8 May 2008

Mucosal IgA responses in influenza virus infections; thoughts for vaccine design

scientific article published on 24 July 2012

NS1-binding protein abrogates the elevation of cell viability by the influenza A virus NS1 protein in association with CRKL.

scientific article published on 9 November 2013

Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models.

scientific article published in February 2016

Neuropathology in Neonatal Mice After Experimental Coxsackievirus B2 Infection Using a Prototype Strain, Ohio-1

scientific article published on 01 February 2020

Neutralizing Antibodies Induced by Gene-Based Hydrodynamic Injection Have a Therapeutic Effect in Lethal Influenza Infection

scientific article published on 24 January 2018

Neutralizing antibody against severe acute respiratory syndrome (SARS)-coronavirus spike is highly effective for the protection of mice in the murine SARS model

scientific article published in February 2009

Neutrophil depletion suppresses pulmonary vascular hyperpermeability and occurrence of pulmonary edema caused by hantavirus infection in C.B-17 SCID mice

scientific article

Next-generation sequencing of miRNAs in clinical samples of Epstein-Barr virus-associated B-cell lymphomas.

scientific article published on 09 February 2017

Non Susceptibility of Neonatal and Adult Rats against the Middle East Respiratory Syndrome Coronavirus.

scientific article published on 18 March 2016

Nucleolin and the packaging signal, psi, promote the budding of human immunodeficiency virus type-1 (HIV-1).

scientific article published in January 2004

Outer membrane vesicles of Porphyromonas gingivalis elicit a mucosal immune response

scientific article

Participation of both host and virus factors in induction of severe acute respiratory syndrome (SARS) in F344 rats infected with SARS coronavirus

scientific article published on 6 December 2006

Passive immune-prophylaxis against influenza virus infection by the expression of neutralizing anti-hemagglutinin monoclonal antibodies from plasmids.

scientific article published in January 2011

Pathogenesis of fulminant monkeypox with bacterial sepsis after experimental infection with West African monkeypox virus in a cynomolgus monkey

scientific article

Pathogenesis of influenza A(H7N9) virus in aged non-human primates

scientific article published on 20 May 2020

Pathogenic characterization of a cervical lymph node derived from a patient with Kawasaki disease

scientific article

Pathological and Virological Analyses of Severe Acute Respiratory Syndrome–Associated Coronavirus Infections in Experimantal Animals

scientific article published on 01 January 2006

Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam.

scientific article

Pathology and virus dispersion in cynomolgus monkeys experimentally infected with severe acute respiratory syndrome coronavirus via different inoculation routes

scientific article published in December 2007

Pathology of Kaposi's Sarcoma-Associated Herpesvirus Infection

scientific article

Persistent infection of influenza virus in irradiated mice and its prevention by intranasal vaccination

scientific article published in January 2002

Plasma 25-hydroxyvitamin d is independently associated with hemoglobin concentration in male subjects with type 2 diabetes mellitus

scientific article

Plasma Antimicrobial Peptide LL-37 Level Is Inversely Associated with HDL Cholesterol Level in Patients with Type 2 Diabetes Mellitus.

scientific article published on 26 March 2014

PolyI:polyC12U adjuvant-combined intranasal vaccine protects mice against highly pathogenic H5N1 influenza virus variants.

scientific article

Potency of gastrointestinal colonization and virulence of Candida auris in a murine endogenous candidiasis

scientific article published on 02 December 2020

Processing of the HTLV-II envelope precursor glycoprotein gp63 by furin is essential for cell fusion activity.

scientific article published in November 2002

Profile of Exosomal and Intracellular microRNA in Gamma-Herpesvirus-Infected Lymphoma Cell Lines

scientific article

Prophylactic effects of chitin microparticles on highly pathogenic H5N1 influenza virus.

scientific article

Protection against influenza virus infection by intranasal administration of C3d-fused hemagglutinin ⬇️

scientific article published on November 7, 2003

Protection against influenza virus infection by intranasal administration of hemagglutinin vaccine with chitin microparticles as an adjuvant

scientific article published in January 2005

Protection against influenza virus infection by intranasal vaccine with surf clam microparticles (SMP) as an adjuvant

scientific article published in July 2006

Protection against influenza virus infection in polymeric Ig receptor knockout mice immunized intranasally with adjuvant-combined vaccines

scientific article published in March 2002

Protective antibody responses against A(H1N1)pdm09 primed by infection and recalled by intranasal vaccination

scientific article published on 30 September 2015

Protective immunity afforded by inactivated H5N1 (NIBRG-14) vaccine requires antibodies against both hemagglutinin and neuraminidase in mice

scientific article published in June 2009

Protective neutralizing influenza antibody response in the absence of T follicular helper cells

scientific article

Rabies virus dissemination in neural tissues of autopsy cases due to rabies imported into Japan from the Philippines: immunohistochemistry

scientific article published in August 2009

Rapid Tumor Formation of Human T-Cell Leukemia Virus Type 1-Infected Cell Lines in Novel NOD-SCID/γcnullMice: Suppression by an Inhibitor against NF-κB ⬇️

scientific article published on May 1, 2003

Rapid quantitative screening assay for SARS-CoV-2 neutralizing antibodies using HiBiT-tagged virus-like particles

scientific article published on 15 September 2020

Reconstitution of cleavage of human immunodeficiency virus type-1 (HIV-1) RNAs

scientific article published in May 2002

Relationship of the quaternary structure of human secretory IgA to neutralization of influenza virus

scientific article published on 8 June 2015

Role of JC virus agnoprotein in virion formation

scientific article

Roles of anti-hemagglutinin IgA and IgG antibodies in different sites of the respiratory tract of vaccinated mice in preventing lethal influenza pneumonia.

scientific article published in June 2003

Serial Section Array Scanning Electron Microscopy Analysis of Cells from Lung Autopsy Specimens following Fatal A/H1N1 2009 Pandemic Influenza Virus Infection

scientific article published on 12 September 2019

Seroprevalence of trichodysplasia spinulosa-associated polyomavirus in Japan.

scientific article

Severe Acute Respiratory Syndrome Coronavirus 2 Infection among Returnees to Japan from Wuhan, China, 2020

scientific article published on 10 April 2020

Severe Fever with Thrombocytopenia Syndrome Phlebovirus causes lethal viral hemorrhagic fever in cats

scientific article published on 19 August 2019

Severe Fever with Thrombocytopenia Syndrome Virus Antigen Detection Using Monoclonal Antibodies to the Nucleocapsid Protein

scientific article

Severe Fever with Thrombocytopenia Syndrome, Japan, 2013-2017

scientific article published on 01 April 2020

Severe fever with thrombocytopenia syndrome virus targets B cells in lethal human infections

scientific article published on 01 February 2020

Spi-B is critical for plasmacytoid dendritic cell function and development

scientific article published on 11 October 2012

Suberoyl bis-hydroxamic acid reactivates Kaposi's sarcoma-associated herpesvirus through histone acetylation and induces apoptosis in lymphoma cells

scientific article published on 16 December 2020

Sudden death of a patient with pandemic influenza (A/H1N1pdm) virus infection by acute respiratory distress syndrome.

scientific article

Synthetic double-stranded RNA poly(I:C) combined with mucosal vaccine protects against influenza virus infection

scientific article

Syrian hamster as an animal model for the study of human influenza virus infection

scientific article published on 6 December 2017

TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection

scientific article published on 05 March 2019

TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus.

scientific article

The Marmoset as an Animal Model of Influenza: Infection With A(H1N1)pdm09 and Highly Pathogenic A(H5N1) Viruses via the Conventional or Tracheal Spray Route.

scientific article

The Microminipig as an Animal Model for Influenza A Virus Infection

scientific article

The RNA- and TRIM25-Binding Domains of Influenza Virus NS1 Protein Are Essential for Suppression of NLRP3 Inflammasome-Mediated Interleukin-1β Secretion

scientific article

The effect of mucoadhesive excipient on the nasal retention time of and the antibody responses induced by an intranasal influenza vaccine

scientific article published on 20 January 2016

The first autopsy case of pandemic influenza (A/H1N1pdm) virus infection in Japan: detection of a high copy number of the virus in type II alveolar epithelial cells by pathological and virological examination.

scientific article

The first identification and retrospective study of Severe Fever with Thrombocytopenia Syndrome in Japan

scientific article

The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses

scientific article

The pathogenesis of 3 neurotropic flaviviruses in a mouse model depends on the route of neuroinvasion after viremia

scientific article published on March 2015

The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan

scientific article

The road to a more effective influenza vaccine: Up to date studies and future prospects

scientific article published on 30 August 2017

Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I.

scientific article published on 19 March 2006

Topoisomerase I and ATP activate cDNA synthesis of human immunodeficiency virus type 1.

scientific article published in June 2002

Topoisomerase I dissociates human immunodeficiency virus type 1 reverse transcriptase from genomic RNAs

scientific article published in January 2004

Transient Appearance of Plasmablasts in the Peripheral Blood of Japanese Patients With Severe Fever With Thrombocytopenia Syndrome

scientific article published on 01 June 2019

Tristetraprolin inhibits HIV-1 production by binding to genomic RNA.

scientific article published on 8 August 2006

Two autopsy cases of severe fever with thrombocytopenia syndrome (SFTS) in Japan: a pathognomonic histological feature and unique complication of SFTS.

scientific article

Unusual manifestation of disseminated herpes simplex virus type 2 infection associated with pharyngotonsilitis, esophagitis, and hemophagocytic lymphohisitocytosis without genital involvement

scientific article published on 17 January 2019

Unusual presentation of a severely ill patient having severe fever with thrombocytopenia syndrome: a case report

scientific article

Viroporin activity of the JC polyomavirus is regulated by interactions with the adaptor protein complex 3.

scientific article published on 28 October 2013

Virulence and pathophysiology of the Congo Basin and West African strains of monkeypox virus in non-human primates

scientific article published on 27 May 2009

Virus-infected peripheral blood plasmablasts in a patient with severe fever with thrombocytopenia syndrome

scientific article published on 22 November 2020

Zika virus protease induces caspase-independent pyroptotic cell death by directly cleaving gasdermin D

scientific article published on 15 November 2020

Zymosan enhances the mucosal adjuvant activity of poly(I:C) in a nasal influenza vaccine

scientific article published on 01 March 2010

cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue

scientific article published on 18 December 2017

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