List of works - Dana Gabuzda

A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2.

scientific article

A machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia

scientific article

A plasma biomarker signature of immune activation in HIV patients on antiretroviral therapy

scientific article

Altered Monoamine and Acylcarnitine Metabolites in HIV-Positive and HIV-Negative Subjects With Depression

scientific article

Applications and limitations of inflammatory biomarkers for studies on neurocognitive impairment in HIV infection

scientific article

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.

scientific article

Bioinformatic prediction programs underestimate the frequency of CXCR4 usage by R5X4 HIV type 1 in brain and other tissues

scientific article

Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era.

scientific article

CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation ⬇️

scientific article published on April 24, 2003

CD4 and MHC class 1 down-modulation activities of nef alleles from brain- and lymphoid tissue-derived primary HIV-1 isolates

scientific article

CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable

scientific article

Cerebrospinal fluid extracellular vesicles and neurofilament light protein as biomarkers of central nervous system injury in HIV-infected patients on antiretroviral therapy.

scientific article

Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment

scientific article

Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.

scientific article

Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion

scientific article

Dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitro

scientific article

Distinct mechanisms of CD4+ and CD8+ T-cell activation and bystander apoptosis induced by human immunodeficiency virus type 1 virions

scientific article

Evolution of the aging brain transcriptome and synaptic regulation

scientific article

Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy.

scientific article

Fractalkine preferentially mediates arrest and migration of CD16+ monocytes

scientific article

Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5delta32 allele

scientific article

Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS.

scientific article published on November 2003

Genomic Landscape of Primary and Recurrent Anal Squamous Cell Carcinomas in Relation to HPV Integration, Copy-Number Variation, and DNA Damage Response Genes

scientific article published on 21 April 2021

HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites.

scientific article

Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells

scientific article

Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein

scientific article

Impact of Antiretroviral Regimens on CSF Viral Escape in a Prospective Multicohort Study of ART-Experienced HIV-1 Infected Adults in the United States.

scientific article published on 3 April 2018

Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

scientific article

Increased risk of anal squamous cell carcinoma in HIV-positive men with prior HBV infection

article

Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers

scientific article

Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy

scientific article published on 22 July 2016

Long-term nitrite inhalant exposure and cancer risk in MSM.

scientific article

Longitudinal Modeling of Depressive Trajectories Among HIV-Infected Men Using Cocaine.

scientific article published on 26 May 2017

Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy

scientific article published on 10 March 2020

Mechanisms of HIV-1 neurotropism

scientific article published on July 2006

Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients

scientific article

Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection

scientific article

Pathogenesis of macrophage tropic HIV-1.

scientific article

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

scientific article

Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source

scientific article published on 16 July 2007

Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors

scientific article

Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection

scientific article

Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation

scientific article published on 22 June 2012

Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment

scientific article published on 05 December 2019

Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1. ⬇️

scientific article published on 30 June 2015

Regulation of APOBEC3 proteins by a novel YXXL motif in human immunodeficiency virus type 1 Vif and simian immunodeficiency virus SIVagm Vif

scientific article published on 24 December 2008

Serological markers for inflammatory bowel disease in AIDS patients with evidence of microbial translocation

scientific article

Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients

scientific article published on 11 November 2020

Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state

scientific article

Temporal Patterns and Drug Resistance in CSF Viral Escape Among ART-Experienced HIV-1 Infected Adults

scientific article

The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.

scholarly article

Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain

scientific article published on 25 March 2009

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

scientific article

Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms

scientific article published on 28 November 2019

Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues

scientific article

Viral phenotypes and antibody responses in long-term survivors infected with attenuated human immunodeficiency virus type 1 containing deletions in the nef and long terminal repeat regions.

scientific article

White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy

scientific article published on 05 November 2019

List of works by Dana Gabuzda

A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2.

A machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia

A plasma biomarker signature of immune activation in HIV patients on antiretroviral therapy

Altered Monoamine and Acylcarnitine Metabolites in HIV-Positive and HIV-Negative Subjects With Depression

Applications and limitations of inflammatory biomarkers for studies on neurocognitive impairment in HIV infection

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.

Bioinformatic prediction programs underestimate the frequency of CXCR4 usage by R5X4 HIV type 1 in brain and other tissues

Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era.

CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation ⬇️

CD4 and MHC class 1 down-modulation activities of nef alleles from brain- and lymphoid tissue-derived primary HIV-1 isolates

CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable

Cerebrospinal fluid extracellular vesicles and neurofilament light protein as biomarkers of central nervous system injury in HIV-infected patients on antiretroviral therapy.

Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment

Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.

Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion

Dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitro

Distinct mechanisms of CD4+ and CD8+ T-cell activation and bystander apoptosis induced by human immunodeficiency virus type 1 virions

Evolution of the aging brain transcriptome and synaptic regulation

Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy.

Fractalkine preferentially mediates arrest and migration of CD16+ monocytes

Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5delta32 allele

Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS.

Genomic Landscape of Primary and Recurrent Anal Squamous Cell Carcinomas in Relation to HPV Integration, Copy-Number Variation, and DNA Damage Response Genes

HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites.

Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells

Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein

Impact of Antiretroviral Regimens on CSF Viral Escape in a Prospective Multicohort Study of ART-Experienced HIV-1 Infected Adults in the United States.

Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

Increased risk of anal squamous cell carcinoma in HIV-positive men with prior HBV infection

Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers

Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy

Long-term nitrite inhalant exposure and cancer risk in MSM.

Longitudinal Modeling of Depressive Trajectories Among HIV-Infected Men Using Cocaine.

Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy

Mechanisms of HIV-1 neurotropism

Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients

Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection

Pathogenesis of macrophage tropic HIV-1.

Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source

Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors

Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection

Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation

Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment

Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1. ⬇️

Regulation of APOBEC3 proteins by a novel YXXL motif in human immunodeficiency virus type 1 Vif and simian immunodeficiency virus SIVagm Vif

Serological markers for inflammatory bowel disease in AIDS patients with evidence of microbial translocation

Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients

Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state

Temporal Patterns and Drug Resistance in CSF Viral Escape Among ART-Experienced HIV-1 Infected Adults

The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.

Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms

Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues

Viral phenotypes and antibody responses in long-term survivors infected with attenuated human immunodeficiency virus type 1 containing deletions in the nef and long terminal repeat regions.

White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy