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List of works by Christian F Singer

7T CEST MRI: A potential imaging tool for the assessment of tumor grade and cell proliferation in breast cancer

scientific article published on 14 March 2019

A Phase II Randomized Study of Neoadjuvant Letrozole Plus Alpelisib for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer (NEO-ORB)

scientific article published on 05 February 2019

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activity

scientific article published on 29 October 2012

A cross-sectional study of elderly Asian and European women with primary operable breast cancer aged 70 and older. Are there differences?

article

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

A new molecular predictor of distant recurrence in ER-positive, HER2-negative breast cancer adds independent information to conventional clinical risk factors.

scientific article

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

scientific article

AGO Austria recommendation on screening and diagnosis of Lynch syndrome (LS).

scientific article

AGO Austria recommendations for genetic testing of patients with ovarian cancer

scientific article

Active (p)CrkL is overexpressed in human malignancies: potential role as a surrogate parameter for therapeutic tyrosine kinase inhibition

scientific article published on February 2006

Adjuvant Sequencing of Tamoxifen and Anastrozole Is Superior to Tamoxifen Alone in Postmenopausal Women with Low Proliferating Breast Cancer

scientific article published on 13 October 2011

Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial

scientific article published on 31 May 2015

Adjuvant denosumab in postmenopausal patients with hormone receptor-positive breast cancer (ABCSG-18): disease-free survival results from a randomised, double-blind, placebo-controlled, phase 3 trial

scientific article published on 19 February 2019

Administration of betaHCG leads to dose-dependent changes of gene expression signature of endometriotic stromal cells

scientific article published on 01 February 2010

Adverse Events of Trastuzumab Emtansine (T-DM1) in the Treatment of HER2-Positive Breast Cancer Patients

scientific article published on 3 December 2017

Adverse Mucocutaneous Reaction to Pertuzumab in a Patient with HER2-Positive Metastatic Breast Cancer.

scientific article published on 26 August 2016

Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 17 May 2018

Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation

scientific article published on 21 May 2018

Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium

scientific article published on 02 December 2019

An international survey of surveillance schemes for unaffected BRCA1 and BRCA2 mutation carriers

scientific article

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

scientific article published on 25 April 2015

Antiestrogenic effects of the fetal estrogen estetrol in women with estrogen-receptor positive early breast cancer

scientific article published on 5 July 2014

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

scientific article

Assessment of a six gene panel for the molecular detection of circulating tumor cells in the blood of female cancer patients.

scientific article published on 3 December 2010

Association between family history, mutation locations, and prevalence of BRCA1 or 2 mutations in ovarian cancer patients

scientific article published on 01 March 2019

Association of BRCA1/2 mutations with FMR1 genotypes: effects on menarcheal and menopausal age.

scientific article published on 23 March 2013

Association of Cytokeratin 5 and Claudin 3 expression with BRCA1 and BRCA2 germline mutations in women with early breast cancer

scientific article published on 15 July 2019

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

scientific article published on 13 November 2019

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

scientific article

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

scientific article published on 10 September 2020

Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality

scientific article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

scientific article published on 31 December 2014

Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO) guideline for prophylaxis with granulocyte colony-stimulating factors (G-CSF) in gynecologic malignancies, including breast cancer ⬇️

scientific article published on June 28, 2012

BRCA1/2 Mutations Appear Embryo-Lethal Unless Rescued by Low (CGG n<26) FMR1 Sub-Genotypes: Explanation for the “BRCA Paradox”? ⬇️

scientific article published on September 12, 2012

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article

Beta-hCG/LH receptor (b-HCG/LH-R) expression is increased in invasive versus preinvasive breast cancer: implications for breast carcinogenesis?

scientific article

Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

scientific article published on 6 September 2016

Blockade of Fatty Acid Synthase Induces Ubiquitination and Degradation of Phosphoinositide-3-Kinase Signaling Proteins in Ovarian Cancer ⬇️

scientific article published on 04 October 2011

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

scientific article published on 11 January 2022

Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers

scientific article

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article

Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation

scientific article published on 30 September 2020

CDK4/6 inhibition in low burden and extensive metastatic breast cancer: summary of an ESMO Open-Cancer Horizons pro and con discussion

scientific article published on 13 November 2019

Cadherin-11 expression is upregulated in invasive human breast cancer

scientific article published on 10 October 2016

Can we prevent BRCA1-associated breast cancer by RANKL inhibition?

scientific article

Cancer Risks Associated With and Pathogenic Variants

scientific article published on 10 May 2022

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Central European BRCA2 mutation carriers: birth cohort status correlates with onset of breast cancer

scientific article published on October 2013

Centrifugation of adipose tissue aspirate causes endothelial cell enrichment

scholarly article

Changes of Socio-demographic data of clients seeking genetic counseling for hereditary breast and ovarian cancer due to the "Angelina Jolie Effect".

scientific article

Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 02 July 2020

Chemotherapy-induced amenorrhea in patients with breast cancer with a BRCA1 or BRCA2 mutation

scientific article published on 26 August 2013

Circulating ovarian steroids and endometrial matrix metalloproteinases (MMPs).

scientific article

Climacteric Complaints after Breast Cancer – Is HRT an Option? ⬇️

scientific article published on June 20, 2008

Co-expressed genes enhance precision of receptor status identification in breast cancer patients

article

Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms

scientific article published on 23 March 2016

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 18 May 2011

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

scientific article

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article published on 2 November 2011

Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers

scientific article

Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

scientific article

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 20 February 2012

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 05 August 2009

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers

scientific article

Complication rates among women undergoing preventive mastectomy: An Austrian registry

scientific article published on 25 May 2020

Contralateral prophylactic mastectomy in women with breast cancer without a family history or genetic predisposition : Consensus statement from the Austrian Gynecologic Oncology Working Group of the Austrian Society of Obstetrics and Gynecology

scientific article published on 18 March 2019

Correction to: Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

scientific article published on 26 February 2020

Correction to: Survival from breast cancer in women with a BRCA2 mutation by treatment

scientific article published on 13 January 2023

Correction: Diagnostic markers for the detection of ovarian cancer in BRCA1 mutation carriers.

scientific article

Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy

scientific article

Cytosine 5-Hydroxymethylation of the LZTS1 Gene Is Reduced in Breast Cancer.

scientific article published on December 2013

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Decrease in gynecological cancer diagnoses during the COVID-19 pandemic: an Austrian perspective

scientific article published on 08 October 2020

Diagnostic markers for the detection of ovarian cancer in BRCA1 mutation carriers.

scientific article published on 15 December 2017

Differential Claudin 3 and EGFR Expression Predicts BRCA1 Mutation in Triple-Negative Breast Cancer

scientific article published on 24 August 2018

Differential expression pattern of estrogen receptors, aromatase, and sulfotransferase in breast cancer tissue and corresponding lymph node metastases ⬇️

scientific article published on December 29, 2010

Differential gene expression profile in breast cancer-derived stromal fibroblasts

scientific article published on 26 September 2007

Differential spatial expression and activation pattern of EGFR and HER2 in human breast cancer.

scientific article

Does the age of breast cancer diagnosis in first-degree relatives impact on the risk of breast cancer in BRCA1 and BRCA2 mutation carriers?

scientific article published on 14 October 2015

Dose-dependent change in biomarkers during neoadjuvant endocrine therapy with fulvestrant: results from NEWEST, a randomized Phase II study

scientific article published on 01 May 2012

Duration of tamoxifen use and the risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article

EGFR activity in HER-2 over-expressing metastatic breast cancer: evidence for simultaneous phosphorylation of Her-2/neu and EGFR.

scientific article

ESR1-Amplification-Associated Estrogen Receptor α Activity in Breast Cancer

scientific article published on 29 August 2016

Effect of Tailored Dose-Dense Chemotherapy vs Standard 3-Weekly Adjuvant Chemotherapy on Recurrence-Free Survival Among Women With High-Risk Early Breast Cancer: A Randomized Clinical Trial

scientific article

Effect of highly purified human chorionic gonadotropin preparations on the gene expression signature of stromal cells derived from endometriotic lesions: potential mechanisms for the therapeutic effect of human chorionic gonadotropin in vivo

scientific article

Effect of lifestyle and reproductive factors on the onset of breast cancer in female BRCA 1 and 2 mutation carriers

scientific article published on 10 December 2015

Effect of tibolone on breast cancer cell proliferation in postmenopausal ER+ patients: results from STEM trial

scientific article

Efficacy and safety of the therapeutic cancer vaccine tecemotide (L-BLP25) in early breast cancer: Results from a prospective, randomised, neoadjuvant phase II study (ABCSG 34)

scientific article published on 20 April 2020

Efficient leukocyte depletion by a novel microfluidic platform enables the molecular detection and characterization of circulating tumor cells

scientific article published on 28 November 2017

Elevated CSF1 serum concentration predicts poor overall survival in women with early breast cancer

scientific article published on 14 October 2013

Estradiol impairs the antiproliferative and proapoptotic effect of Zoledronic acid in hormone sensitive breast cancer cells in vitro.

scientific article published on 25 September 2017

Estrogen receptor beta and matrix metalloproteinase 1 are coexpressed in uterine endometrium and endometriotic lesions of patients with endometriosis

scientific article published on 01 October 2005

Estrogen sulfotransferase expression in endometrial stromal sarcomas: an immunohistochemical study

scientific article published on 02 January 2007

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

scientific article

Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers

scientific article

Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers

scientific article

Exemestane as primary systemic treatment for hormone receptor positive post-menopausal breast cancer patients: a phase II trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-17).

scientific article published on 22 December 2007

Expression of COX-2, p16, and Ki67 in the range from normal breast tissue to breast cancer

scientific article published on 05 November 2020

Expression of Sex Steroid Receptors and their Co-Factors in Normal and Malignant Breast Tissue: AIB1 is a Carcinoma-Specific Co-Activator ⬇️

scientific article published on March 1, 2003

Expression of tyrosine kinases in human malignancies as potential targets for kinase-specific inhibitors

scientific article published in December 2004

Extracellular matrix proteins influence phenotype and cytokine expression in human breast cancer cell lines

scientific article published on 01 April 2002

Factors influencing agreement of breast cancer luminal molecular subtype by Ki67 labeling index between core needle biopsy and surgical resection specimens

scientific article published on 07 May 2020

Factors predicting severe perineal trauma during childbirth: role of forceps delivery routinely combined with mediolateral episiotomy

scientific article published in March 2005

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

scientific article

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Gene expression information improves reliability of receptor status in breast cancer patients

scientific article

Gene expression of PMP22 is an independent prognostic factor for disease-free and overall survival in breast cancer patients

scientific article published on 15 December 2010

Gene expression profiling of cervical tissue during physiological cervical effacement

scientific article published in January 2005

Gene expression signatures of breast tissue before and after cross-sex hormone therapy in female-to-male transsexuals.

scientific article published on 26 May 2010

Genetic counselling and testing of susceptibility genes for therapeutic decision-making in breast cancer—an European consensus statement and expert recommendations

article

Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers

scientific article

Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers

scientific article published on January 2009

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

article

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

Guidance Statement On BRCA1/2 Tumor Testing in Ovarian Cancer Patients

scientific article published in June 2017

HER Specific TKIs Exert Their Antineoplastic Effects on Breast Cancer Cell Lines through the Involvement of STAT5 and JNK.

scientific article published on 6 January 2016

HER2 overexpression and activation, and tamoxifen efficacy in receptor-positive early breast cancer

scientific article published on 26 November 2008

HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer ⬇️

scientific article published on August 1, 2013

Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers

scientific article

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

scientific article published on 01 April 2019

Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzumab-based therapy in patients with metastatic breast cancer

scientific article

High-level ERBB2 gene amplification is associated with a particularly short time-to-metastasis, but results in a high rate of complete response once trastuzumab-based therapy is offered in the metastatic setting.

scientific article

Histopathological characterization of ulcerated breast cancer and comparison to their non-ulcerated counterparts

scientific article published on 28 December 2014

Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers

scientific article published on 01 August 2018

Hormone replacement therapy after menopause and risk of breast cancer in BRCA1 mutation carriers: a case-control study

scientific article published on 16 January 2016

Identification and management of familial breast cancer in Austria.

scientific article published on 30 November 2017

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk

scientific article published on 27 March 2013

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

scientific article published on 27 April 2016

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

scientific article

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

IgG based immunome analyses of breast cancer patients reveal underlying signaling pathways

scientific article published on 28 May 2019

Impact of AdipoR1 expression on breast cancer development

scientific article published on 13 January 2010

Impact of Body Mass Index on the Efficacy of Endocrine Therapy in Premenopausal Patients With Breast Cancer: An Analysis of the Prospective ABCSG-12 Trial

scientific article published on 09 May 2011

Impact of Breast Surgery in Primary Metastasized Breast Cancer: Outcomes of the Prospective Randomized Phase III ABCSG-28 POSYTIVE Trial

scientific article

Impact of lifestyle factors on preneoplastic changes in prophylactic oophorectomies of BRCA mutation carriers.

scientific article published in March 2012

Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation

scientific article

Improving comprehension of genetic counseling for hereditary breast and ovarian cancer clients with a visual tool

scientific article published in PLoS ONE

Incomplete surgical resection of ductal carcinomas in situ results in activation of ERBB2 in residual breast cancer cells.

scientific article

Increase in ezrin expression from benign to malignant breast tumours

scientific article

Influence of Orally Administered Probiotic Lactobacillus Strains on Vaginal Microbiota in Women with Breast Cancer during Chemotherapy: A Randomized Placebo-Controlled Double-Blinded Pilot Study.

scientific article published on 27 October 2017

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

scientific article

Insulin-like growth factor (IGF)-I and IGF-II serum concentrations in patients with benign and malignant breast lesions: free IGF-II is correlated with breast cancer size

scientific article

Insulin-like growth factor-1 receptor (IGF-1R) expression does not predict for resistance to trastuzumab-based treatment in patients with Her-2/neu overexpressing metastatic breast cancer

scientific article published on 24 September 2005

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

scientific article

Interleukin 1 system and sex steroid receptor expression in human breast cancer: interleukin 1alpha protein secretion is correlated with malignant phenotype.

scientific article published on October 2003

International rates of breast reconstruction after prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers

scientific article

Is breast cancer in young Asian women more aggressive than in Caucasians? A cross-sectional analysis ⬇️

scientific article published on April 13, 2013

Is the CTS5 a helpful decision-making tool in the extended adjuvant therapy setting?

scholarly article

Ixazomib in combination with carboplatin in pretreated women with advanced triple-negative breast cancer, a phase I/II trial of the AGMT (AGMT MBC-10 trial)

scientific article published on 06 November 2018

MMP-2 and MMP-9 expression in breast cancer-derived human fibroblasts is differentially regulated by stromal-epithelial interactions

scientific article published on 01 March 2002

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article

Mammography screening and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a prospective study

article

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

scientific article published on 19 June 2019

Methyl-binding domain protein-based DNA isolation from human blood serum combines DNA analyses and serum-autoantibody testing.

scientific article published on 06 September 2011

Microarray Normalization Revisited for Reproducible Breast Cancer Biomarkers

scientific article published on 06 August 2020

Microarray analysis identifies distinct gene expression profiles associated with histological subtype in human osteosarcoma

scientific article

Modern Risk Assessment for Individualizing Treatment Concepts in Early-stage Breast Cancer

Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes

scientific article

Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers

scientific article published on 07 July 2009

Monitoring of serum Her-2/neu predicts histopathological response to neoadjuvant trastuzumab-based therapy for breast cancer.

scientific article

Monitoring of serum Her-2/neu predicts response and progression-free survival to trastuzumab-based treatment in patients with metastatic breast cancer

scientific article published in March 2004

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

scientific article published on 10 January 2017

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

scientific article published on 15 February 2018

Neoadjuvant Endocrine Therapy in Breast Cancer

scientific article

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

No evidence that GATA3 rs570613 SNP modifies breast cancer risk

scientific article published on 11 December 2008

Non-surgical prevention strategies in women with hereditary breast and ovarian cancer syndromes

scientific article published on 07 May 2020

Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers

scientific article

On the evidence for ESR1 amplification in breast cancer

article

Oophorectomy after menopause and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article published on 7 May 2012

Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers

scientific article published on 12 February 2019

Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study

scientific article published on 01 April 2018

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

scientific article

PIK3CA Amplification Associates with Aggressive Phenotype but Not Markers of AKT-MTOR Signaling in Endometrial Carcinoma

scientific article published on 15 November 2018

PTEN expression as a predictor for the response to trastuzumab-based therapy in Her-2 overexpressing metastatic breast cancer.

scientific article

Pathologic Complete Response With Six Compared With Three Cycles of Neoadjuvant Epirubicin Plus Docetaxel and Granulocyte Colony-Stimulating Factor in Operable Breast Cancer: Results of ABCSG-14

scientific article published on 01 May 2007

Pathological Complete Response to Neoadjuvant Trastuzumab Is Dependent on HER2/CEP17 Ratio in HER2-Amplified Early Breast Cancer.

scientific article published on 31 January 2017

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011

Patient satisfaction after breast cancer surgery : A prospective clinical trial

scientific article published on 03 September 2020

Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer

scientific article published on 28 May 2019

Pharmacological modulation of IGF serum concentrations as a therapeutic approach to control the growth of malignant breast tumors.

scientific article

Pharmacological modulation of local feedback mechanisms as a therapeutic approach in breast cancer treatment

scientific article published on December 2003

Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer.

scientific article published on January 2013

Phase II study on the efficacy and safety of Lapatinib administered beyond disease progression and combined with vinorelbine in HER-2/neu- positive advanced breast cancer: results of the CECOG LaVie trial.

scientific article published on 18 February 2016

Physical state and expression of HPV DNA in benign and dysplastic cervical tissue: different levels of viral integration are correlated with lesion grade

scientific article published on 01 March 2004

Plasma osteoprotegerin and breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

scientific article published on 15 July 2020

Postoperative CMF Does Not Ameliorate Poor Outcomes in Women With Residual Invasive Breast Cancer After Neoadjuvant Epirubicin/Docetaxel Chemotherapy

scientific article published on 18 June 2015

Predicting the efficacy of trastuzumab-based therapy in breast cancer: current standards and future strategies

scientific article published on 04 March 2008

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

scientific article

Prediction of Distant Recurrence Using EndoPredict Among Women with ER+, HER2- Node-Positive and Node-Negative Breast Cancer Treated with Endocrine Therapy Only

scientific article published on 07 May 2019

Predictive value of molecular subtypes in premenopausal women with hormone receptor-positive early breast cancer: Results from the ABCSG Trial 5

scientific article published on 16 June 2020

Principles and method of action of targeted therapies ⬇️

scientific article published on August 24, 2010

Profiling of Cross-Functional Peptidases Regulated Circulating Peptides in BRCA1 Mutant Breast Cancer.

scientific article published on 08 April 2016

Prognostic assessment and adjuvant treatment strategies within early-stage, sporadic triple negative breast cancer patients.

scientific article

Prognostic relevance of pretherapeutic gamma-glutamyltransferase in patients with primary metastatic breast cancer

scientific article published on 27 April 2015

Prophylactic long-acting granulocyte-colony stimulating factors (G-CSF) in gynecologic malignancies: an oncologic expert statement

scientific article published on 15 October 2015

Prospective evaluation of alcohol consumption and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article published on 03 May 2015

Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers

scientific article published in June 2018

Proteomic analysis in human breast cancer: identification of a characteristic protein expression profile of malignant breast epithelium

scientific article published in March 2006

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quantitation of p95HER2 in Paraffin Sections by Using a p95-Specific Antibody and Correlation with Outcome in a Cohort of Trastuzumab-Treated Breast Cancer Patients ⬇️

scientific article published on July 27, 2010

Quantitative Sodium MR Imaging at 7 T: Initial Results and Comparison with Diffusion-weighted Imaging in Patients with Breast Tumors.

scientific article published on 27 January 2016

RANKL/RANK control Brca1 mutation-driven mammary tumors

scientific article published on 31 May 2016

Recurrent malignant Triton tumour: first report on a long time survivor.

scientific article published in May 2003

Response prediction to neoadjuvant chemotherapy: comparison between pre-therapeutic gene expression profiles and in vitro chemosensitivity assay

scientific article

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

scientific article published on 16 January 2020

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

scientific article published on June 2017

Selective spatial upregulation of intratumoral stromal aromatase in breast cancer patients: evidence for imbalance of local estrogen metabolism

scientific article published in December 2006

Serum EGFR levels and efficacy of trastuzumab-based therapy in patients with metastatic breast cancer

scientific article published on 02 December 2005

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Single-agent trastuzumab versus trastuzumab plus cytotoxic chemotherapy in metastatic breast cancer: a single-institution experience

scientific article published on 01 February 2005

Systemic HCG treatment in patients with endometriosis: a new perspective for a painful disease

scientific article

Tamoxifen and Anastrozole As a Sequencing Strategy: A Randomized Controlled Trial in Postmenopausal Patients With Endocrine-Responsive Early Breast Cancer From the Austrian Breast and Colorectal Cancer Study Group

scientific article published on 23 January 2012

Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

scientific article published on 05 August 2013

The EndoPredict score predicts response to neoadjuvant chemotherapy and neoendocrine therapy in hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer patients from the ABCSG-34 trial

scientific article published on 02 June 2020

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

scientific article published on 01 November 2019

The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With or Mutations

The PAM50 risk-of-recurrence score predicts risk for late distant recurrence after endocrine therapy in postmenopausal women with endocrine-responsive early breast cancer

scientific article published on 11 February 2014

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells.

scientific article published on 3 November 2010

The association between smoking and cancer incidence in BRCA1 and BRCA2 mutation carriers

scientific article published on 13 January 2018

The effect of obesity on pathological complete response and survival in breast cancer patients receiving uncapped doses of neoadjuvant anthracycline-taxane-based chemotherapy

scientific article published on 7 April 2017

The efficacy of trastuzumab in Her-2/neu-overexpressing metastatic breast cancer is independent of p53 status

scientific article published on 29 April 2005

The impact of pregnancy on breast cancer survival in women who carry a BRCA1 or BRCA2 mutation

scientific article published on 18 October 2013

The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: an international prospective cohort study

scientific article published on 3 April 2013

The pre-analytical processing of blood samples for detecting biomarkers on protein microarrays

scientific article published on 09 February 2015

The predictive value of suspicious sonographic characteristics in atypical cyst-like breast lesions ⬇️

scientific article published on October 28, 2010

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

scientific article published on 8 March 2011

Therapeutic Strategies in Triple-Negative Breast Cancer.

scientific article

Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers

scientific article

Tissue array-based expression of transglutaminase-2 in human breast and ovarian cancer

scientific article published on 07 July 2006

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

scientific article published on 01 March 2020

Treatment of Bone Metastases in Patients with Advanced Breast Cancer.

scientific article

Triple-modality screening trial for familial breast cancer underlines the importance of magnetic resonance imaging and questions the role of mammography and ultrasound regardless of patient mutation status, age, and breast density.

scientific article

Tuberin and p27 expression in breast cancer patients with or without BRCA germline mutations ⬇️

scientific article published on May 21, 2013

Tumor characteristics and recurrence patterns in triple negative breast cancer: a comparison between younger (<65) and elderly (≥65) patients

scientific article

Use of high-throughput arrays for profiling differentially expressed proteins in normal and malignant tissues

scientific article

Use of high-throughput protein array for profiling of differentially expressed proteins in normal and malignant breast tissue

scientific article published on 01 August 2004

Use of risk-reducing surgeries in a prospective cohort of 1,499 BRCA1 and BRCA2 mutation carriers

scientific article

[Guideline for the prevention and early detection of breast and ovarian cancer in high risk patients, particularly in women from HBOC (hereditary breast and ovarian cancer) families]

scientific article published on 28 May 2012

[Principles and method of action of targeted therapies.]

scientific article published on 24 August 2010

beta-HCG/LH receptor (beta-HCG/LH-R) expression in eutopic endometrium and endometriotic implants: evidence for beta-HCG sensitivity of endometriosis.

scientific article published in July 2008

cDNA array analysis of cytobrush-collected normal and malignant cervical epithelial cells: a feasibility study

scientific article published in April 2005

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