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List of works by Marcelo Gama de Abreu

"Why, sometimes I've believed as many as six impossible things before breakfast." Lewis Carroll, In "Through the looking-glass, and what Alice found there".

scientific article

A new adaptive controller for volume-controlled mechanical ventilation in small animals

scientific article published in April 2014

A novel adaptive control system for noisy pressure-controlled ventilation: a numerical simulation and bench test study

scientific article published on 25 September 2009

Ability of dynamic airway pressure curve profile and elastance for positive end-expiratory pressure titration.

scientific article

Acute respiratory distress syndrome: we can't miss regional lung perfusion!

scientific article published on 18 March 2015

Adaptive control system for volume-controlled ventilation in small animals

scientific article published on 06 September 2012

Albumin versus crystalloid solutions in patients with the acute respiratory distress syndrome: a systematic review and meta-analysis

scientific article published on 09 January 2014

Anesthesia and Monitoring in Small Laboratory Mammals Used in Anesthesiology, Respiratory and Critical Care Research: A Systematic Review on the Current Reporting in Top-10 Impact Factor Ranked Journals

scientific article (publication date: 2015)

Approaches to ventilation in intensive care

scientific article

Are height and weight estimates in ED patients reliable for setting the ventilator?

scientific article published on 5 June 2017

Assessing the eligibility of a non-invasive continuous blood pressure measurement technique for application during total intravenous anaesthesia

scientific article published on 9 February 2016

Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data.

scientific article

Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis

scientific article published on 01 September 2018

Association between tidal volume size, duration of ventilation, and sedation needs in patients without acute respiratory distress syndrome: an individual patient data meta-analysis.

scientific article

Association of remote imaging photoplethysmography and cutaneous perfusion in volunteers

scientific article published on 05 October 2020

Associations between changes in oxygenation, dead space and driving pressure induced by the first prone position session and mortality in patients with acute respiratory distress syndrome

scientific article published on 01 December 2019

Associations between positive end-expiratory pressure and outcome of patients without ARDS at onset of ventilation: a systematic review and meta-analysis of randomized controlled trials.

scientific article

Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual patient data analysis : Mechanical ventilation during E

article

Atelectasis during general anaesthesia for surgery: should we treat atelectasis or the patient?

scientific article published on 06 April 2020

Balanced versus isotonic saline resuscitation-a systematic review and meta-analysis of randomized controlled trials in operation rooms and intensive care units.

scientific article published on August 2017

Better Physiology does not Necessarily Translate Into Improved Clinical Outcome

scientific article

Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome

scientific article published on 01 June 2018

Biological Impact of Transpulmonary Driving Pressure in Experimental Acute Respiratory Distress Syndrome

scientific article published in August 2015

Biphasic positive airway pressure minimizes biological impact on lung tissue in mild acute lung injury independent of etiology

scientific article

Characterization of Respiratory Patterns During Assisted Mechanical Ventilation in Experimental ARDS

scientific article published on 07 September 2013

Chronic obstructive pulmonary disease

scientific article published on 01 February 2012

Close down the lungs and keep them resting to minimize ventilator-induced lung injury.

scientific article published on 20 March 2018

Coherence analysis overestimates the role of baroreflex in governing the interactions between heart period and systolic arterial pressure variabilities during general anesthesia

scientific article published on 08 April 2013

Comparative Effects of Volutrauma and Atelectrauma on Lung Inflammation in Experimental Acute Respiratory Distress Syndrome

scientific article published on 31 March 2016

Comparative effects of flow vs. volume-controlled one-lung ventilation on gas exchange and respiratory system mechanics in pigs

scientific article published on 18 December 2020

Comparative effects of neurally adjusted ventilatory assist and variable pressure support on lung and diaphragmatic function in a model of acute respiratory distress syndrome: A randomised animal study

scientific article published on 06 July 2020

Comparative effects of proportional assist and variable pressure support ventilation on lung function and damage in experimental lung injury

scientific article published in September 2012

Comparative effects of vaporized perfluorohexane and partial liquid ventilation in oleic acid-induced lung injury

scientific article (publication date: February 2006)

Comparison between effects of pressure support and pressure-controlled ventilation on lung and diaphragmatic damage in experimental emphysema

scientific article published on 19 October 2016

Comparison of 68Ga- and fluorescence-labeled microspheres for measurement of relative pulmonary perfusion in anesthetized pigs

scientific article published on 05 June 2018

Comparison of Static and Dynamic 18F-FDG PET/CT for Quantification of Pulmonary Inflammation in Acute Lung Injury

scientific article published on 03 May 2019

Computed tomographic assessment of lung weights in trauma patients with early posttraumatic lung dysfunction

scientific article published on 25 February 2011

Continuous external negative pressure improves oxygenation and respiratory mechanics in Experimental Lung Injury in Pigs - A pilot proof-of-concept trial

scientific article published on 18 December 2020

Development and validation of a score to predict postoperative respiratory failure in a multicentre European cohort: A prospective, observational study

scientific article published on 13 February 2015

Distribution of regional lung aeration and perfusion during conventional and noisy pressure support ventilation in experimental lung injury

scientific article published on 26 January 2011

ESA Clinical Trials Network 2012: LAS VEGAS--Local Assessment of Ventilatory Management during General Anaesthesia for Surgery and its effects on Postoperative Pulmonary Complications: a prospective, observational, international, multicentre cohort

scientific article published on 01 May 2013

Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial

scientific article published on 01 June 2019

Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial

scientific article published on 01 March 2018

Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial

scientific article published in The Journal of the American Medical Association

Effect of a Lower vs Higher Positive End-Expiratory Pressure Strategy on Ventilator-Free Days in ICU Patients Without ARDS: A Randomized Clinical Trial

scientific article published on 09 December 2020

Effects of Obesity on Pulmonary Inflammation and Remodeling in Experimental Moderate Acute Lung Injury

scientific article published on 29 May 2019

Effects of Positive End-Expiratory Pressure and Spontaneous Breathing Activity on Regional Lung Inflammation in Experimental Acute Respiratory Distress Syndrome

scientific article published on 01 April 2019

Effects of Protective Mechanical Ventilation With Different PEEP Levels on Alveolar Damage and Inflammation in a Model of Open Abdominal Surgery: A Randomized Study in Obese Versus Non-obese Rats

scientific article published on 17 December 2019

Effects of Volatile Anesthetics on Mortality and Postoperative Pulmonary and Other Complications in Patients Undergoing Surgery: A Systematic Review and Meta-analysis.

scientific article published on 11 April 2016

Effects of assisted and variable mechanical ventilation on cardiorespiratory interactions in anesthetized pigs

scientific article

Effects of crystalloid, hyper-oncotic albumin, and iso-oncotic albumin on lung and kidney damage in experimental acute lung injury

scientific article published on 16 July 2019

Effects of different levels of pressure support variability in experimental lung injury

scientific article published in February 2009

Effects of higher PEEP and recruitment manoeuvres on mortality in patients with ARDS: a systematic review, meta-analysis, meta-regression and trial sequential analysis of randomized controlled trials

scientific article published on 18 December 2020

Effects of intravascular volume replacement on lung and kidney function and damage in nonseptic experimental lung injury

scientific article published in February 2013

Effects of peep on lung injury, pulmonary function, systemic circulation and mortality in animals with uninjured lungs-a systematic review

scientific article published in January 2018

Effects of perfluorohexane vapor in the treatment of experimental lung injury.

scientific article published in April 2010

Effects of pressure support ventilation on ventilator-induced lung injury in mild acute respiratory distress syndrome depend on level of positive end-expiratory pressure

scientific article

Effects of sigh during pressure control and pressure support ventilation in pulmonary and extrapulmonary mild acute lung injury

scientific article

Effects of ultraprotective ventilation, extracorporeal carbon dioxide removal, and spontaneous breathing on lung morphofunction and inflammation in experimental severe acute respiratory distress syndrome

scientific article published in March 2015

Effects of vaporized perfluorohexane and partial liquid ventilation on regional distribution of alveolar damage in experimental lung injury

scientific article published on 08 November 2006

Effects of variable versus non-variable controlled mechanical ventilation: response to comment on Br J Anaesth 2020; 124: 430-439

scientific article published on 06 April 2020

Effects of variable versus nonvariable controlled mechanical ventilation on pulmonary inflammation in experimental acute respiratory distress syndrome in pigs

scientific article published on 04 February 2020

Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study

scientific article published on 4 October 2016

Erratum to Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial.

scientific article published on June 2017

Exogenous Glutamine in Respiratory Diseases: Myth or Reality?

scientific article

Expanded endothelial progenitor cells mitigate lung injury in septic mice

scientific article

Fast Versus Slow Recruitment Maneuver at Different Degrees of Acute Lung Inflammation Induced by Experimental Sepsis

scientific article published on February 2016

Fluids and blood transfusions: the corner pillars of perioperative period

scientific article published on 01 December 2012

Focal ischemic stroke leads to lung injury and reduces alveolar macrophage phagocytic capability in rats

scientific article published on 05 October 2018

General Anesthesia Closes the Lungs: Keep Them Resting

scientific article

Good things come in threes: prevention, early recognition and treatment of organ dysfunction to improve postoperative outcome

scientific article published on 16 June 2016

High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial.

scientific article published on 2 June 2014

High-flow nasal cannula oxygen therapy in patients undergoing thoracic surgery: current evidence and practice

scientific article published on 01 February 2019

Higher levels of spontaneous breathing induce lung recruitment and reduce global stress/strain in experimental lung injury.

scientific article published in March 2014

Higher levels of spontaneous breathing reduce lung injury in experimental moderate acute respiratory distress syndrome

scientific article published in November 2014

Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury

scientific article

Impact of intravascular volume replacement and transfusion on outcome: where are we now?

scientific article published on December 2012

Impact of pressure profile and duration of recruitment maneuvers on morphofunctional and biochemical variables in experimental lung injury

scientific article published in May 2011

In Reply

In Reply

In reply

Incidence of mortality and morbidity related to postoperative lung injury in patients who have undergone abdominal or thoracic surgery: a systematic review and meta-analysis.

scientific article

Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis

scientific article published in January 2018

International multicenter observational study on assessment of ventilatory management during general anaesthesia for robotic surgery and its effects on postoperative pulmonary complication (AVATaR): study protocol and statistical analysis plan

scientific article published on 23 August 2018

Intraabdominal Pressure Targeted Positive End-expiratory Pressure during Laparoscopic Surgery: An Open-label, Nonrandomized, Crossover, Clinical Trial

scientific article published on 01 April 2020

Intraoperative Ventilation Strategies to Reduce Pulmonary Complications in Obese Patients-Reply

scientific article published on 01 November 2019

Intraoperative immunomodulatory effects of sevoflurane versus total intravenous anesthesia with propofol in bariatric surgery (the OBESITA trial): study protocol for a randomized controlled pilot trial.

scientific article published on 28 May 2019

Intraoperative mechanical ventilation practice in thoracic surgery patients and its association with postoperative pulmonary complications: results of a multicenter prospective observational study

scientific article published on 22 July 2020

Intraoperative protective mechanical ventilation for prevention of postoperative pulmonary complications: a comprehensive review of the role of tidal volume, positive end-expiratory pressure, and lung recruitment maneuvers

scientific article published on 29 June 2015

Intraoperative ventilation strategies to prevent postoperative pulmonary complications: Systematic review, meta-analysis, and trial sequential analysis

scientific article

Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study

scientific article published on 02 April 2020

Intratidal Analysis of Intraoperative Respiratory System Mechanics: Keep it Simple.

scientific article published in February 2018

Is mechanical power the final word on ventilator-induced lung injury?-no

scholarly article by Robert Huhle et al published October 2018 in Annals of translational medicine

Kinetics of plasma biomarkers of inflammation and lung injury in surgical patients with or without postoperative pulmonary complications.

scientific article published on 9 February 2017

Liquid- and air-filled catheters without balloon as an alternative to the air-filled balloon catheter for measurement of esophageal pressure

scientific article

Lung Functional and Biologic Responses to Variable Ventilation in Experimental Pulmonary and Extrapulmonary Acute Respiratory Distress Syndrome

scientific article published on 9 March 2016

Lung injury prediction models to improve perioperative management: let's hit the bull's-eye!

scientific article published on 01 July 2011

Lung protection during one-lung ventilation: Another piece in the puzzle

scientific article published on 01 October 2018

Lung recruitment in ARDS: We are still confused, but on a higher PEEP level ⬇️

scientific article published on February 9, 2012

Lung-Protective Ventilation With Low Tidal Volumes and the Occurrence of Pulmonary Complications in Patients Without Acute Respiratory Distress Syndrome: A Systematic Review and Individual Patient Data Analysis

scientific article

Lung-protective ventilation for the surgical patient: international expert panel-based consensus recommendations

scientific article published on 03 October 2019

Magnetic Resonance Imaging for Quantitative Assessment of Lung Aeration: A Pilot Translational Study

scientific article published on 13 August 2018

Mechanical power of ventilation is associated with mortality in critically ill patients: an analysis of patients in two observational cohorts

scientific article published on 05 October 2018

Mechanical ventilation during anaesthesia: challenges and opportunities for investigating the respiration-related cardiovascular oscillations ⬇️

scientific article published on 06 July 2011

Mechanical ventilation in acute lung injury/acute respiratory distress syndrome: more protection, better outcome

scientific article published on 01 April 2012

Mechanical ventilation in neurocritical care patients: a systematic literature review

scientific article published on 16 September 2016

Mechanical ventilation strategies for the surgical patient

scientific article published on August 2015

Modeling intra-abdominal volume and respiratory driving pressure during pneumoperitoneum insufflation - a patient-level data meta-analysis

scientific article published on 24 December 2020

Modulation of stress versus time product during mechanical ventilation influences inflammation as well as alveolar epithelial and endothelial response in rats

scientific article published in January 2015

Myocardial Function during Low versus Intermediate Tidal Volume Ventilation in Patients without Acute Respiratory Distress Syndrome

scientific article published on 11 February 2020

Neuromuscular blocking agents and postoperative pulmonary complications

scientific article published on 14 September 2018

New and conventional strategies for lung recruitment in acute respiratory distress syndrome

scientific article published on 09 March 2010

Noisy pressure support ventilation: a pilot study on a new assisted ventilation mode in experimental lung injury.

scientific article published in March 2008

Non-ventilatory approaches to prevent postoperative pulmonary complications

scientific article

Nonventilatory strategies to prevent postoperative pulmonary complications

scientific article published on April 2013

Normalization of mechanical power to anthropometric indices: impact on its association with mortality in critically ill patients

scientific article published on 08 October 2019

One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model

scientific article

Open lung approach vs acute respiratory distress syndrome network ventilation in experimental acute lung injury ⬇️

scientific article published on June 7, 2011

Open-lung Ventilation Strategy during General Anesthesia

scientific article published on 24 September 2020

PEEP in thoracic anesthesia: PROS and CONS

scientific article published on 10 December 2020

PERISCOPE study: predicting post-operative pulmonary complications in Europe

scientific article published on 01 June 2011

PRactice of VENTilation in Middle-Income Countries (PRoVENT-iMIC): rationale and protocol for a prospective international multicentre observational study in intensive care units in Asia.

scientific article

PReVENT--protective ventilation in patients without ARDS at start of ventilation: study protocol for a randomized controlled trial

scientific article published on 24 May 2015

Perfluorohexane vapor has only minor effects on spatial pulmonary blood flow distribution in isolated rabbit lungs

scientific article published in April 2005

Perioperative complications of obese patients

scientific article published on 14 June 2016

Pilot study of vaporization of perfluorohexane during high-frequency oscillatory ventilation in experimental acute lung injury

scientific article published on November 2010

Positive end-expiratory pressure during surgery - Authors' reply

scientific article published on 7 November 2014

Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT.

scientific article

Pressure support improves oxygenation and lung protection compared to pressure-controlled ventilation and is further improved by random variation of pressure support

scientific article

Pressure support ventilation and biphasic positive airway pressure improve oxygenation by redistribution of pulmonary blood flow.

scientific article published in September 2009

Pretreatment with perfluorohexane vapor attenuates fMLP-induced lung injury in isolated perfused rabbit lungs.

scientific article published on August 2010

Pros and cons of recruitment maneuvers in acute lung injury and acute respiratory distress syndrome

scientific article published on August 2010

Prospective external validation of a predictive score for postoperative pulmonary complications

scientific article published on August 2014

Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial

scientific article

Protective mechanical ventilation during general anesthesia for open abdominal surgery improves postoperative pulmonary function

scientific article published on June 2013

Protective versus Conventional Ventilation for Surgery: A Systematic Review and Individual Patient Data Meta-analysis.

scientific article

Protocol for a systematic review and individual patient data meta-analysis of benefit of so-called lung-protective ventilation settings in patients under general anesthesia for surgery

scientific article

Pulmonary embolism in mechanically ventilated patients: what the eye doesn't see, the heart can still grieve over

scientific article published on 01 December 2012

Pulmonary levels of biomarkers for inflammation and lung injury in protective versus conventional one-lung ventilation for oesophagectomy: A randomised clinical trial

scientific article published on 04 December 2019

RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: protocol for a randomized controlled trial.

scientific article published on 9 May 2018

Rationale and study design of PROVHILO - a worldwide multicenter randomized controlled trial on protective ventilation during general anesthesia for open abdominal surgery ⬇️

scientific article

Rationale and study design of ViPS - variable pressure support for weaning from mechanical ventilation: study protocol for an international multicenter randomized controlled open trial

scientific article published on 31 October 2013

Recruitment maneuvers modulate epithelial and endothelial cell response according to acute lung injury etiology

scientific article published in October 2013

Regional distribution of transpulmonary pressure

Regional lung aeration and ventilation during pressure support and biphasic positive airway pressure ventilation in experimental lung injury

scientific article

Reply to: high versus low positive end-expiratory pressure for abdominal surgery

scientific article published on 01 January 2018

Respiratory System Mechanics During Low Versus High Positive End-Expiratory Pressure in Open Abdominal Surgery: A Substudy of PROVHILO Randomized Controlled Trial.

scientific article published on 19 June 2017

Role of shear stress in ventilator-induced lung injury - Authors' reply

scientific article published on 20 June 2016

Short-term effects of noisy pressure support ventilation in patients with acute hypoxemic respiratory failure

scientific article

Should the lungs be rested or open during anaesthesia to prevent postoperative complications?

scientific article published on 19 January 2018

Spontaneous breathing activity in acute lung injury and acute respiratory distress syndrome

scientific article published on April 2012

Spontaneous breathing in mild and moderate versus severe acute respiratory distress syndrome

scientific article published on February 2014

Static and Dynamic Transpulmonary Driving Pressures Affect Lung and Diaphragm Injury during Pressure-controlled versus Pressure-support Ventilation in Experimental Mild Lung Injury in Rats

scientific article published on 20 November 2019

Temporal Changes in Ventilator Settings in Patients With Uninjured Lungs: A Systematic Review

scientific article published on 01 July 2019

The European Medicines Agency and the Authorization for Hydroxyethyl starch Containing Solutions-Killing the Cow to Get Rid of Ticks?

scientific article published on 01 June 2017

The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study

scientific article published on 01 September 2018

The authors reply

The biological effects of higher and lower positive end-expiratory pressure in pulmonary and extrapulmonary acute lung injury with intra-abdominal hypertension

scientific article

The effects of preoperative moderate to severe anaemia on length of hospital stay: A propensity score-matched analysis in non-cardiac surgery patients

scientific article published on 04 January 2021

The effects of salbutamol on epithelial ion channels depend on the etiology of acute respiratory distress syndrome but not the route of administration

scientific article

The obese patient undergoing nonbariatric surgery

scientific article published on 15 March 2016

Tidal volumes during general anesthesia: size does matter!

scientific article published in May 2012

Ultra-low-dose sequential computed tomography for quantitative lung aeration assessment-a translational study

scientific article published on 4 April 2017

Use of computed tomography scanning to guide lung recruitment and adjust positive-end expiratory pressure

scientific article published on June 2011

Vaporized perfluorohexane attenuates ventilator-induced lung injury in isolated, perfused rabbit lungs

scientific article published in March 2005

Variability in Tidal Volume Affects Lung and Cardiovascular Function Differentially in a Rat Model of Experimental Emphysema

scientific article

Variable Tidal Volumes Improve Lung Protective Ventilation Strategies in Experimental Lung Injury

scientific article published on 16 January 2009

Variable Ventilation Improved Respiratory System Mechanics and Ameliorated Pulmonary Damage in a Rat Model of Lung Ischemia-Reperfusion

scientific article

Variable stretch reduces the pro-inflammatory response of alveolar epithelial cells

scientific article published on 15 August 2017

Variable ventilation from bench to bedside

scientific article

Variable ventilation improves pulmonary function and reduces lung damage without increasing bacterial translocation in a rat model of experimental pneumonia

scientific article

Variable versus conventional lung protective mechanical ventilation during open abdominal surgery: study protocol for a randomized controlled trial

scientific article published on 2 May 2014

Ventilator-induced Lung Injury: Power to the Mechanical Power

scientific article published in November 2016

White blood cell counts and plasma C3a have synergistic predictive value in patients at risk for acute respiratory distress syndrome ⬇️

scientific article published on June 1, 1998

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