List of works - Agnes Jager

"Atypical" atypical femur fractures and use of bisphosphonates

scientific article published on September 2016

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

scientific article published on 02 August 2012

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium

scientific article

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

scientific article

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

scientific article published on 16 December 2015

Adjuvant radiotherapy for primary breast cancer in BRCA1 and BRCA2 mutation carriers and risk of contralateral breast cancer with special attention to patients irradiated at younger age.

scientific article

An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients

scientific article published on 18 February 2016

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

scientific article published on 25 April 2015

Angiogenesis- and Hypoxia-Associated Proteins as Early Indicators of the Outcome in Patients with Metastatic Breast Cancer Given First-Line Bevacizumab-Based Therapy

scientific article published on 28 January 2016

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

scientific article

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

scientific article published on 13 November 2019

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

scientific article published on 18 August 2021

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

scientific article

Augmentation of Endoxifen Exposure in Tamoxifen-Treated Women Following SSRI Switch

scientific article published on 8 October 2015

C-reactive protein and soluble vascular cell adhesion molecule-1 are associated with elevated urinary albumin excretion but do not explain its link with cardiovascular risk

scientific article

Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients.

scientific article published on 7 June 2015

Circulating tumor cell enumeration by the CellSearch system: the clinician's guide to breast cancer treatment?

scientific article published on 23 December 2014

Denosumab in breast cancer treatment ⬇️

scientific article published on March 29, 2013

Diagnostic and therapeutic ionizing radiation and the risk of a first and second primary breast cancer, with special attention for BRCA1 and BRCA2 mutation carriers: a critical review of the literature

scientific article published on 08 December 2014

Do primary mammary osteosarcoma and chondrosarcoma exist? A review of a large multi-institutional series of malignant matrix-producing breast tumours

scientific article published on 22 October 2012

ESR1 mutations: Moving towards guiding treatment decision-making in metastatic breast cancer patients

scientific article

Efficacy of opioid rotation to continuous parenteral hydromorphone in advanced cancer patients failing on other opioids

scientific article

Ex vivo tumor culture systems for functional drug testing and therapy response prediction

scientific article

Extent of ductal carcinoma in situ according to breast cancer subtypes: a population-based cohort study

scientific article published on 18 June 2016

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Functional Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects

article

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

scientific article published in July 2021

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

scientific article

Individualization of tamoxifen therapy: much more than just CYP2D6 genotyping

scientific article

Inflammation and fatigue dimensions in advanced cancer patients and cancer survivors ⬇️

scientific article published on June 26, 2012

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

scientific article

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

scientific article

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

scientific article published in October 2021

MicroRNA related polymorphisms and breast cancer risk

scientific article

Microalbuminuria and Peripheral Arterial Disease Are Independent Predictors of Cardiovascular and All-Cause Mortality, Especially Among Hypertensive Subjects

article

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Neutrophil-guided dosing of anthracycline-cyclophosphamide-containing chemotherapy in patients with breast cancer: a feasibility study

scientific article

Omitting re-excision for focally positive margins after breast-conserving surgery does not impair disease-free and overall survival

scientific article

Prediction and clinical utility of a contralateral breast cancer risk model

scientific article published on 17 December 2019

Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts

scientific article published on 11 April 2020

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor

scientific article published on 17 October 2016

Rare germline copy number variants (CNVs) and breast cancer risk

scientific article published on 18 January 2022

Sensitivity to first-line chemotherapy for metastatic breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article

Sensitivity to systemic therapy for metastatic breast cancer in CHEK2 1100delC mutation carriers

scientific article

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer

scientific article published on 5 February 2017

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

scientific article published on April 2015

The effect of immediate breast reconstruction on the timing of adjuvant chemotherapy: a systematic review

scientific article

The efficacy of taxane chemotherapy for metastatic breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article

The risk of primary and contralateral breast cancer after ovarian cancer in BRCA1/BRCA2 mutation carriers: Implications for counseling

scientific article

The role of genetic breast cancer susceptibility variants as prognostic factors

scientific article

Toxicity of (neo)adjuvant chemotherapy for BRCA1- and BRCA2-associated breast cancer

scientific article published on 9 April 2016

Tumor slice culture system to assess drug response of primary breast cancer

scientific article published in January 2015

Understanding drugs in breast cancer through drug sensitivity screening

scientific article

Unjustified prescribing of CYP2D6 inhibiting SSRIs in women treated with tamoxifen ⬇️

scientific article published on June 13, 2013

von Willebrand Factor, C-Reactive Protein, and 5-Year Mortality in Diabetic and Nondiabetic Subjects

article

List of works by Agnes Jager

"Atypical" atypical femur fractures and use of bisphosphonates

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

Adjuvant radiotherapy for primary breast cancer in BRCA1 and BRCA2 mutation carriers and risk of contralateral breast cancer with special attention to patients irradiated at younger age.

An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

Angiogenesis- and Hypoxia-Associated Proteins as Early Indicators of the Outcome in Patients with Metastatic Breast Cancer Given First-Line Bevacizumab-Based Therapy

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

Augmentation of Endoxifen Exposure in Tamoxifen-Treated Women Following SSRI Switch

C-reactive protein and soluble vascular cell adhesion molecule-1 are associated with elevated urinary albumin excretion but do not explain its link with cardiovascular risk

Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients.

Circulating tumor cell enumeration by the CellSearch system: the clinician's guide to breast cancer treatment?

Denosumab in breast cancer treatment ⬇️

Diagnostic and therapeutic ionizing radiation and the risk of a first and second primary breast cancer, with special attention for BRCA1 and BRCA2 mutation carriers: a critical review of the literature

Do primary mammary osteosarcoma and chondrosarcoma exist? A review of a large multi-institutional series of malignant matrix-producing breast tumours

ESR1 mutations: Moving towards guiding treatment decision-making in metastatic breast cancer patients

Efficacy of opioid rotation to continuous parenteral hydromorphone in advanced cancer patients failing on other opioids

Ex vivo tumor culture systems for functional drug testing and therapy response prediction

Extent of ductal carcinoma in situ according to breast cancer subtypes: a population-based cohort study

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Functional Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

Individualization of tamoxifen therapy: much more than just CYP2D6 genotyping

Inflammation and fatigue dimensions in advanced cancer patients and cancer survivors ⬇️

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

MicroRNA related polymorphisms and breast cancer risk

Microalbuminuria and Peripheral Arterial Disease Are Independent Predictors of Cardiovascular and All-Cause Mortality, Especially Among Hypertensive Subjects

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Neutrophil-guided dosing of anthracycline-cyclophosphamide-containing chemotherapy in patients with breast cancer: a feasibility study

Omitting re-excision for focally positive margins after breast-conserving surgery does not impair disease-free and overall survival

Prediction and clinical utility of a contralateral breast cancer risk model

Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor

Rare germline copy number variants (CNVs) and breast cancer risk

Sensitivity to first-line chemotherapy for metastatic breast cancer in BRCA1 and BRCA2 mutation carriers

Sensitivity to systemic therapy for metastatic breast cancer in CHEK2 1100delC mutation carriers

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

The effect of immediate breast reconstruction on the timing of adjuvant chemotherapy: a systematic review

The efficacy of taxane chemotherapy for metastatic breast cancer in BRCA1 and BRCA2 mutation carriers

The risk of primary and contralateral breast cancer after ovarian cancer in BRCA1/BRCA2 mutation carriers: Implications for counseling

The role of genetic breast cancer susceptibility variants as prognostic factors

Toxicity of (neo)adjuvant chemotherapy for BRCA1- and BRCA2-associated breast cancer

Tumor slice culture system to assess drug response of primary breast cancer

Understanding drugs in breast cancer through drug sensitivity screening

Unjustified prescribing of CYP2D6 inhibiting SSRIs in women treated with tamoxifen ⬇️

von Willebrand Factor, C-Reactive Protein, and 5-Year Mortality in Diabetic and Nondiabetic Subjects