List of works - Steffen Massberg

2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS

scientific article published on 26 August 2017

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo

scientific article

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

scientific article

Alcohol consumption, sinus tachycardia, and cardiac arrhythmias at the Munich Octoberfest: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW).

scientific article

Assessment of right ventricular sympathetic dysfunction in patients with arrhythmogenic right ventricular cardiomyopathy: An 123I-metaiodobenzylguanidine SPECT/CT study

scientific article published on 17 December 2018

Attenuation of cardiac hypertrophy by G-CSF is associated with enhanced migration of bone marrow-derived cells.

scientific article published on 8 March 2015

Biodegradable polymer drug-eluting stents reduce the risk of stent thrombosis at 4 years in patients undergoing percutaneous coronary intervention: a pooled analysis of individual patient data from the ISAR-TEST 3, ISAR-TEST 4, and LEADERS randomize

scientific article

Cerebral Embolic Protection during Transcatheter Aortic-Valve Replacement

scientific article published in 2022

Collapse of a Bioresorbable Novolimus-Eluting Coronary Scaffold

scientific article published on 8 December 2015

Critical role of platelet glycoprotein ibα in arterial remodeling

scientific article published on 30 December 2014

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

scientific article

Direct crosstalk between mast cell-TNF and TNFR1-expressing endothelia mediates local tissue inflammation

scientific article

Effects of 2 different antiplatelet regimens with abciximab or tirofiban on platelet function in patients undergoing coronary stenting ⬇️

scientific article (publication date: November 2003)

Effects of Statins on Platelet Inhibition by a High Loading Dose of Clopidogrel ⬇️

scientific article (publication date: 4 November 2003)

Effects of aspirin and clopidogrel versus oral anticoagulation on platelet function and on coagulation in patients with nonvalvular atrial fibrillation (CLAFIB)

scientific article

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

scientific article

Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation

scientific article

Fractalkine Is Expressed in Early and Advanced Atherosclerotic Lesions and Supports Monocyte Recruitment via CX3CR1 ⬇️

scientific article published on August 20, 2012

Functional comparison of induced pluripotent stem cell- and blood-derived GPIIbIIIa deficient platelets

scientific article

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

scientific journal article

Hematopoietic stem and progenitor cell trafficking

scientific article

IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation

scientific article

Identification of novel downstream targets of platelet glycoprotein VI activation by differential proteome analysis: implications for thrombus formation.

scientific article

Image quality and radiation dose of a prospectively electrocardiography-triggered high-pitch data acquisition strategy for coronary CT angiography: The multicenter, randomized PROTECTION IV study

scientific article published on 12 March 2015

Impact of Dabigatran versus Phenprocoumon on ADP Induced Platelet Aggregation in Patients with Atrial Fibrillation with or without Concomitant Clopidogrel Therapy (the Dabi-ADP-1 and Dabi-ADP-2 Trials).

scientific article published in July 2015

Intermittent capillary perfusion in rat pancreas grafts following short- and long-term preservation in University of Wisconsin solution

scientific article published in April 2006

Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells

scientific article

Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue

scientific article

Molecular imaging of cardiac CXCR4 expression in a mouse model of acute myocardial infarction using a novel 68Ga-mCXCL12 PET tracer

scientific article published on 16 July 2020

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.

scientific article published on 26 March 2012

Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes

scientific article published in 2024

Myeloid-specific deletion of tumor suppressor PTEN augments neutrophil transendothelial migration during inflammation

scientific article published on June 2009

Neutrophils promote venular thrombosis by shaping the rheological environment for platelet aggregation

scientific article published on 04 November 2019

Novel trafficking routes for hematopoietic stem and progenitor cells

scientific article

Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation

scientific article published on 11 September 2020

Patrolling the vascular borders: platelets in immunity to infection and cancer

scientific article published on 13 August 2019

Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis

scientific article

Platelet dysfunction and inhibition of multiple electrode platelet aggregometry caused by penicillin

scientific article

Platelet function and coagulation in patients with STEMI and peri-interventional clopidogrel plus heparin vs. prasugrel plus bivalirudin therapy (BRAVE 4 substudy).

scientific article published on 19 November 2015

Platelet mitochondrial membrane depolarization reflects disease severity in patients with sepsis and correlates with clinical outcome

scientific article

Platelets contribute to postnatal occlusion of the ductus arteriosus

scientific article

Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo

scientific article

Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement

scientific article (publication date: May 2003)

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection

scientific article published on 23 February 2022

Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor

scientific article (publication date: 15 October 2002)

Role of platelets in the pathophysiology of acute coronary syndrome

scientific article published on May 2003

Six-month outcome after transcatheter edge-to-edge repair of severe tricuspid regurgitation in patients with heart failure

scientific article published on 6 February 2018

Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P).

scientific article

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

scientific article

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

scientific article published on 17 March 2021

The DEDICATE Trial: An independent all-comers trial of transcatheter aortic valve implantation vs. surgical aortic valve replacement in patients at low to intermediate operative risk is recruiting patients

scientific article published on 01 January 2019

The proteasome regulates collagen-induced platelet aggregation via nuclear-factor-kappa-B (NFĸB) activation

scientific article

Three-dimensional transoesophageal echocardiography for the assessment of clip attachment to the leaflets in percutaneous edge-to-edge repair of the mitral valve

scientific article published on April 22, 2013

Thrombosis as an intravascular effector of innate immunity ⬇️

scientific article published on December 7, 2012

Transcatheter Repair of Primary Tricuspid Valve Regurgitation Using the MitraClip System

scientific article

Vascular surveillance by haptotactic blood platelets in inflammation and infection

scientific article published on 13 November 2020

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models

scientific article

List of works by Steffen Massberg

2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

Alcohol consumption, sinus tachycardia, and cardiac arrhythmias at the Munich Octoberfest: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW).

Assessment of right ventricular sympathetic dysfunction in patients with arrhythmogenic right ventricular cardiomyopathy: An 123I-metaiodobenzylguanidine SPECT/CT study

Attenuation of cardiac hypertrophy by G-CSF is associated with enhanced migration of bone marrow-derived cells.

Biodegradable polymer drug-eluting stents reduce the risk of stent thrombosis at 4 years in patients undergoing percutaneous coronary intervention: a pooled analysis of individual patient data from the ISAR-TEST 3, ISAR-TEST 4, and LEADERS randomize

Cerebral Embolic Protection during Transcatheter Aortic-Valve Replacement

Collapse of a Bioresorbable Novolimus-Eluting Coronary Scaffold

Critical role of platelet glycoprotein ibα in arterial remodeling

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

Direct crosstalk between mast cell-TNF and TNFR1-expressing endothelia mediates local tissue inflammation

Effects of 2 different antiplatelet regimens with abciximab or tirofiban on platelet function in patients undergoing coronary stenting ⬇️

Effects of Statins on Platelet Inhibition by a High Loading Dose of Clopidogrel ⬇️

Effects of aspirin and clopidogrel versus oral anticoagulation on platelet function and on coagulation in patients with nonvalvular atrial fibrillation (CLAFIB)

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation

Fractalkine Is Expressed in Early and Advanced Atherosclerotic Lesions and Supports Monocyte Recruitment via CX3CR1 ⬇️

Functional comparison of induced pluripotent stem cell- and blood-derived GPIIbIIIa deficient platelets

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

Hematopoietic stem and progenitor cell trafficking

IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation

Identification of novel downstream targets of platelet glycoprotein VI activation by differential proteome analysis: implications for thrombus formation.

Image quality and radiation dose of a prospectively electrocardiography-triggered high-pitch data acquisition strategy for coronary CT angiography: The multicenter, randomized PROTECTION IV study

Impact of Dabigatran versus Phenprocoumon on ADP Induced Platelet Aggregation in Patients with Atrial Fibrillation with or without Concomitant Clopidogrel Therapy (the Dabi-ADP-1 and Dabi-ADP-2 Trials).

Intermittent capillary perfusion in rat pancreas grafts following short- and long-term preservation in University of Wisconsin solution

Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells

Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue

Molecular imaging of cardiac CXCR4 expression in a mouse model of acute myocardial infarction using a novel 68Ga-mCXCL12 PET tracer

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.

Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes

Myeloid-specific deletion of tumor suppressor PTEN augments neutrophil transendothelial migration during inflammation

Neutrophils promote venular thrombosis by shaping the rheological environment for platelet aggregation

Novel trafficking routes for hematopoietic stem and progenitor cells

Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation

Patrolling the vascular borders: platelets in immunity to infection and cancer

Platelet GPIIb supports initial pulmonary retention but inhibits subsequent proliferation of melanoma cells during hematogenic metastasis

Platelet dysfunction and inhibition of multiple electrode platelet aggregometry caused by penicillin

Platelet function and coagulation in patients with STEMI and peri-interventional clopidogrel plus heparin vs. prasugrel plus bivalirudin therapy (BRAVE 4 substudy).

Platelet mitochondrial membrane depolarization reflects disease severity in patients with sepsis and correlates with clinical outcome

Platelets contribute to postnatal occlusion of the ductus arteriosus

Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo

Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement

Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection

Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor

Role of platelets in the pathophysiology of acute coronary syndrome

Six-month outcome after transcatheter edge-to-edge repair of severe tricuspid regurgitation in patients with heart failure

Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P).

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

The DEDICATE Trial: An independent all-comers trial of transcatheter aortic valve implantation vs. surgical aortic valve replacement in patients at low to intermediate operative risk is recruiting patients

The proteasome regulates collagen-induced platelet aggregation via nuclear-factor-kappa-B (NFĸB) activation

Three-dimensional transoesophageal echocardiography for the assessment of clip attachment to the leaflets in percutaneous edge-to-edge repair of the mitral valve

Thrombosis as an intravascular effector of innate immunity ⬇️

Transcatheter Repair of Primary Tricuspid Valve Regurgitation Using the MitraClip System

Vascular surveillance by haptotactic blood platelets in inflammation and infection

von Willebrand factor-mediated platelet adhesion is critical for deep vein thrombosis in mouse models