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List of works by Ambrose L Cheung

1H, 13C, and 15N backbone and side-chain chemical shift assignment of the staphylococcal MazF mRNA interferase

scientific article

A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings

scientific article

A quinolinol-based small molecule with anti-MRSA activity that targets bacterial membrane and promotes fermentative metabolism

scientific article published on 12 July 2017

A recA-LexA-dependent pathway mediates ciprofloxacin-induced fibronectin binding in Staphylococcus aureus

scientific article published on 29 December 2003

Activation and transcriptional interaction between agr RNAII and RNAIII in Staphylococcus aureus in vitro and in an experimental endocarditis model.

scientific article

Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection

scientific article

Aspirin treatment is associated with a significantly decreased risk of Staphylococcus aureus bacteremia in hemodialysis patients with tunneled catheters

scientific article (publication date: March 2007)

Beta-lactams interfering with PBP1 induce Panton-Valentine leukocidin expression by triggering sarA and rot global regulators of Staphylococcus aureus.

scientific article

Bypassing the restriction system to improve transformation of Staphylococcus epidermidis

scientific article published on 30 May 2017

Characterization of MazFSa, an endoribonuclease from Staphylococcus aureus

scientific article published on 12 October 2007

Characterization of RNA Helicase CshA and Its Role in Protecting mRNAs and Small RNAs of Staphylococcus aureus Strain Newman

scientific article published on 11 January 2016

Characterization of a novel small molecule that potentiates β-lactam activity against gram-positive and gram-negative pathogens.

scientific article

Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria.

scientific article

Contribution of teg49 small RNA in the 5' upstream transcriptional region of sarA to virulence in Staphylococcus aureus

scientific article

Control of the Staphylococcus aureus Toxic Shock tst Promoter by the Global Regulator SarA

scientific article published on September 24, 2010

Coordinated regulation by AgrA, SarA, and SarR to control agr expression in Staphylococcus aureus.

scientific article

Correction for Kim et al., Contribution of teg49 Small RNA in the 5' Upstream Transcriptional Region of sarA to Virulence in Staphylococcus aureus

scientific article published on 23 June 2016

Crystal Structure of the SarS Protein from Staphylococcus aureus

scientific article

Crystallization of the Staphylococcus aureus MazF mRNA interferase

scientific article published on February 25, 2011

CspA regulation of Staphylococcus aureus carotenoid levels and σB activity is controlled by YjbH and Spx

scientific article published on 22 May 2019

Disparity in the in vitro versus in vivo regulation of fibronectin-binding proteins by 2 global regulators, saeRS and sigB, in Staphylococcus aureus

scientific article

Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging

scientific article published on 10 January 2008

Dysregulation of mprF and dltABCD expression among daptomycin-non-susceptible MRSA clinical isolates

scientific article published on 27 April 2016

Effect of clpP and clpC deletion on persister cell number in Staphylococcus aureus

scientific article published on July 2016

Exploring innate glycopeptide resistance mechanisms in Staphylococcus aureus

scientific article

Expression of SarX, a negative regulator of agr and exoprotein synthesis, is activated by MgrA in Staphylococcus aureus

scientific article published on June 2006

Extracellular proteases inhibit protein-dependent biofilm formation in Staphylococcus aureus.

scientific article published on 31 October 2009

Fibrinogen Depletion Attenuates Staphyloccocus aureus Infection by Preventing Density-Dependent Virulence Gene Up-Regulation

scientific article published on November 15, 2003

From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence?

scientific article published on 01 November 2012

Genetic evidence for an alternative citrate-dependent biofilm formation pathway in Staphylococcus aureus that is dependent on fibronectin binding proteins and the GraRS two-component regulatory system

scientific article published on 17 March 2008

Global regulation of virulence determinants in Staphylococcus aureus by the SarA protein family

scientific article

Heparin stimulates Staphylococcus aureus biofilm formation

scientific article published on August 2005

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

scientific article

Identification of sarV (SA2062), a new transcriptional regulator, is repressed by SarA and MgrA (SA0641) and involved in the regulation of autolysis in Staphylococcus aureus

scientific article published on August 2004

Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model

scientific article

Impact of the Novel Prophage ϕSA169 on Persistent Methicillin-Resistant Staphylococcus aureus Endovascular Infection

scientific article published on 30 June 2020

Impact of vancomycin on sarA-mediated biofilm formation: role in persistent endovascular infections due to methicillin-resistant Staphylococcus aureus

scientific article published on 07 January 2014

Impacts of sarA and agr in Staphylococcus aureus strain Newman on fibronectin-binding protein A gene expression and fibronectin adherence capacity in vitro and in experimental infective endocarditis

scientific article published on March 2004

Importance of bacillithiol in the oxidative stress response of Staphylococcus aureus.

scientific article published on 28 October 2013

Improving transformation of Staphylococcus aureus belonging to the CC1, CC5 and CC8 clonal complexes

scientific article published on 25 March 2015

In vivo bioluminescence imaging to evaluate systemic and topical antibiotics against community-acquired methicillin-resistant Staphylococcus aureus-infected skin wounds in mice

scientific article published on 3 December 2012

Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense

scholarly article

Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo

scientific article published in November 2007

Influences of sigmaB and agr on expression of staphylococcal enterotoxin B (seb) in Staphylococcus aureus.

scientific article published in May 2004

Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus

scientific article published on 14 May 2007

Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation

scientific journal article

Interspecies interactions induce exploratory motility in

scientific article published on 12 November 2019

MgrA Governs Adherence, Host Cell Interaction, and Virulence in a Murine Model of Bacteremia Due to Staphylococcus aureus

scientific article published on 01 August 2019

MgrA represses biofilm formation in Staphylococcus aureus

scientific article published on 13 October 2008

Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscess

scientific article

Molecular basis of resistance to muramidase and cationic antimicrobial peptide activity of lysozyme in staphylococci

scientific article

Mouse model of chronic post-arthroplasty infection: noninvasive in vivo bioluminescence imaging to monitor bacterial burden for long-term study

scientific article published on 11 August 2011

Multiple virulence factors are required for Staphylococcus aureus-induced apoptosis in endothelial cells

scientific article published in August 2005

MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus

scientific article published in January 2006

Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice

scientific article

Noninvasive in vivo imaging to evaluate immune responses and antimicrobial therapy against Staphylococcus aureus and USA300 MRSA skin infections

scientific article

Overexpression of MazFsa in Staphylococcus aureus induces bacteriostasis by selectively targeting mRNAs for cleavage

scientific article published on 23 January 2009

Persister formation in Staphylococcus aureus is associated with ATP depletion.

scientific article published on 18 April 2016

Proteolytic regulation of toxin-antitoxin systems by ClpPC in Staphylococcus aureus

scientific article published on 28 December 2009

Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis

scientific article published on 01 May 2019

Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus

scientific article published on March 2005

Regulation of Staphylococcus aureus alpha-toxin gene (hla) expression by agr, sarA, and sae in vitro and in experimental infective endocarditis

scientific article published on 27 September 2006

Regulation of Staphylococcus aureus type 5 capsular polysaccharides by agr and sarA in vitro and in an experimental endocarditis model

scientific article published on 01 August 2002

Regulation of the mazEF toxin-antitoxin module in Staphylococcus aureus and its impact on sigB expression

scientific article published on 30 January 2009

Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus

scientific article published on January 2004

Repression of hla by rot is dependent on sae in Staphylococcus aureus

scientific article published on 3 January 2008

Revisiting the genomes of the Staphylococcus aureus strains NCTC 8325 and RN4220

scientific article published on 12 March 2012

Role of ArlRS in Autolysis in Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus Strains

scientific article published on December 2, 2011

Role of PknB kinase in antibiotic resistance and virulence in community-acquired methicillin-resistant Staphylococcus aureus strain USA300.

scientific article published on 14 June 2010

Role of Purine Biosynthesis in Persistent Methicillin-Resistant Staphylococcus aureus Infection

scientific article published on 01 September 2018

Role of adaptor TrfA and ClpPC in controlling levels of SsrA-tagged proteins and antitoxins in Staphylococcus aureus

scientific article published on 15 September 2014

Role of mgrA and sarA in methicillin-resistant Staphylococcus aureus autolysis and resistance to cell wall-active antibiotics

scientific article published on January 2009

Role of the distal sarA promoters in SarA expression in Staphylococcus aureus

scientific article published on July 2005

Salicylic acid activates sigma factor B by rsbU-dependent and -independent mechanisms

scientific article

Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus

scientific article (publication date: July 2003)

Salicylic acid diminishes Staphylococcus aureus capsular polysaccharide type 5 expression

scientific article

Salicylic acid enhances Staphylococcus aureus extracellular adhesin protein expression.

scientific article

SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development.

scientific article published on April 2005

SarA of Staphylococcus aureus binds to the sarA promoter to regulate gene expression

scientific article

SarA positively controls bap-dependent biofilm formation in Staphylococcus aureus

scientific article

SarT influences sarS expression in Staphylococcus aureus

scientific article published on September 2003

SarZ promotes the expression of virulence factors and represses biofilm formation by modulating SarA and agr in Staphylococcus aureus

scientific article published on 27 October 2008

Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance

scientific article (publication date: June 2014)

Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections

scientific article (publication date: April 2015)

Site-specific mutation of the sensor kinase GraS in Staphylococcus aureus alters the adaptive response to distinct cationic antimicrobial peptides

scientific article

Small RNA Teg49 is derived from a sarA transcript and regulates virulence genes independent of SarA in Staphylococcus aureus

scientific article published on 13 November 2017

Staphylococcal enterotoxin A-activated regulatory T cells promote allergen-specific TH2 response to intratracheal allergen inoculation

scientific article published on 8 June 2016

Staphylococcus aureus PBP4 is essential for beta-lactam resistance in community-acquired methicillin-resistant strains

scientific article

Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung

scientific article

Staphylococcus aureus escapes more efficiently from the phagosome of a cystic fibrosis bronchial epithelial cell line than from its normal counterpart

scientific article published on May 2006

Staphylococcus aureus evades the extracellular antimicrobial activity of mast cells by promoting its own uptake

scientific article published on 8 June 2011

Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1

scientific article

Stp1 and Stk1: The Yin and Yang of Vancomycin Sensitivity and Virulence in Vancomycin-Intermediate Staphylococcus aureus Strains

scientific article published on 05 April 2012

Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics

scientific article

Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus

scholarly article

The Genomic Aspect of Virulence, Sepsis, and Resistance to Killing Mechanisms in Staphylococcus aureus

scientific article

The Global Regulon sarA Regulates β-Lactam Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus In Vitro and in Endovascular Infections

scientific article published on 19 August 2016

The GraS Sensor in Staphylococcus aureus Mediates Resistance to Host Defense Peptides Differing in Mechanisms of Action

scientific article published on 23 November 2015

The SarA protein family of Staphylococcus aureus

scientific article

The Staphylococcus aureus Two-Component Regulatory System, GraRS, Senses and Confers Resistance to Selected Cationic Antimicrobial Peptides

scientific article published on October 10, 2011

The Toxin-Antitoxin MazEF Drives Staphylococcus aureus Biofilm Formation, Antibiotic Tolerance, and Chronic Infection

scientific article published on 26 November 2019

The expression of alpha-haemolysin is required for Staphylococcus aureus phagosomal escape after internalization in CFT-1 cells

scientific article

The staphylococcal respiratory response regulator SrrAB induces ica gene transcription and polysaccharide intercellular adhesin expression, protecting Staphylococcus aureus from neutrophil killing under anaerobic growth conditions

article

The staphylococcus-specific gene rsr represses agr and virulence in Staphylococcus aureus

scientific article published on 9 August 2010

Thymidine-dependent Staphylococcus aureus small-colony variants are associated with extensive alterations in regulator and virulence gene expression profiles

scientific article published on July 2005

Tissue culture assays used to analyze invasion by Staphylococcus aureus

scientific article published in February 2007

Transcriptional regulation of the agr locus and the identification of DNA binding residues of the global regulatory protein SarR in Staphylococcus aureus

scientific article published on 01 June 2006

Transposon disruption of the complex I NADH oxidoreductase gene (snoD) in Staphylococcus aureus is associated with reduced susceptibility to the microbicidal activity of thrombin-induced platelet microbicidal protein 1.

scientific article

Whole-genome sequencing of Staphylococcus aureus strain RN4220, a key laboratory strain used in virulence research, identifies mutations that affect not only virulence factors but also the fitness of the strain

scientific article published on 4 March 2011

YpdA, a putative bacillithiol disulfide reductase, contributes to cellular redox homeostasis and virulence in Staphylococcus aureus

scientific article published on 17 February 2019

sarU, a sarA homolog, is repressed by SarT and regulates virulence genes in Staphylococcus aureus

scientific article

α-Toxin Regulates Local Granulocyte Expansion from Hematopoietic Stem and Progenitor Cells in Staphylococcus aureus-Infected Wounds

scientific article published on 21 July 2017