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List of works by William W. Hay Jr.

50 Years Ago in The Journal of Pediatrics: Diazoxide Treatment for Idiopathic Hypoglycemia of Infancy

scientific article published on 01 October 2017

A Chronic Fetal Leucine Infusion Potentiates Fetal Insulin Secretion and Increases Pancreatic Islet Size, Vascularity, and β Cells in Late-Gestation Sheep

scientific article published on 29 May 2020

A cautionary response to SMFM statement: pharmacological treatment of gestational diabetes

scientific article published on 28 June 2018

A physiological increase in insulin suppresses gluconeogenic gene activation in fetal sheep with sustained hypoglycemia ⬇️

scientific article published on August 29, 2012

Acute supplementation of amino acids increases net protein accretion in IUGR fetal sheep

scientific article

Adaptation of ovine fetal pancreatic insulin secretion to chronic hypoglycaemia and euglycaemic correction.

scientific article

Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in Mice.

scientific article published on 10 January 2017

Adiponectin Promotes Maternal β-Cell Expansion Through Placental Lactogen Expression

scientific article published on 21 October 2020

Adiponectin enhances mouse fetal fat deposition

scientific article

Alert Newborn Infants Are Ready to Feed and Raise Their Glucose Concentration

scientific article published on 22 January 2019

Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction.

scientific article

Challenges in nourishing the intrauterine growth-restricted foetus - Lessons learned from studies in the intrauterine growth-restricted foetal sheep

scientific article published on 30 March 2016

Characterization of glucose transporter 8 (GLUT8) in the ovine placenta of normal and growth restricted fetuses.

scientific article published in January 2004

Characterization of glucose-insulin responsiveness and impact of fetal number and sex difference on insulin response in the sheep fetus ⬇️

scientific article published on February 22, 2011

Chronic Hyperinsulinemia Increases Myoblast Proliferation in Fetal Sheep Skeletal Muscle.

scientific article published on 06 April 2016

Chronic anemic hypoxemia attenuates glucose-stimulated insulin secretion in fetal sheep.

scientific article published on 18 January 2017

Chronic anemic hypoxemia increases plasma glucagon and hepatic PCK1 mRNA in late-gestation fetal sheep.

scientific article published on 11 May 2016

Chronic fetal hypoglycemia inhibits the later steps of stimulus-secretion coupling in pancreatic beta-cells

scientific article published on 09 January 2007

Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep.

scientific article published on 04 December 2007

Chronically Increased Amino Acids Improve Insulin Secretion, Pancreatic Vascularity, and Islet Size in Growth-Restricted Fetal Sheep

scientific article published on 8 August 2016

Continuous glucose monitoring for diagnosis and treatment of neonatal hypoglycemia

scientific article

Coordinated changes in hepatic amino acid metabolism and endocrine signals support hepatic glucose production during fetal hypoglycemia

scientific article

Decreased nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect

scientific article published on 28 March 2006

Describing hypoglycemia--definition or operational threshold?

scientific article

Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.

scientific article

Differential effects of chronic pulsatile versus chronic constant maternal hyperglycemia on fetal pancreatic β-cells.

scientific article published on 22 October 2012

Differential effects of intrauterine growth restriction and a hypersinsulinemic-isoglycemic clamp on metabolic pathways and insulin action in the fetal liver

scientific article published on 13 February 2019

Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction

article

Effect of hyperinsulinemia on amino acid utilization and oxidation independent of glucose metabolism in the ovine fetus

scientific article published on 25 July 2006

Effects of acute hyperinsulinemia on insulin signal transduction and glucose transporters in ovine fetal skeletal muscle

scientific article published on 11 November 2004

Effects of chronic hyperinsulinemia on metabolic pathways and insulin signaling in the fetal liver

scientific article published on 24 August 2020

Effects of chronic hypoglycemia and euglycemic correction on lysine metabolism in fetal sheep

scientific article published on 03 February 2009

Energy requirements, protein-energy metabolism and balance, and carbohydrates in preterm infants

scientific article published on 11 April 2014

Enhanced insulin secretion and insulin sensitivity in young lambs with placental insufficiency-induced intrauterine growth restriction.

scientific article published on 10 May 2017

Exogenous amino acids suppress glucose oxidation and potentiate hepatic glucose production in late gestation fetal sheep

scientific article published on 8 February 2017

Fetoplacental transport and utilization of amino acids in IUGR--a review

scientific article

Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction

scientific article published on January 2009

High-fat feeding reprograms maternal energy metabolism and induces long-term postpartum obesity in mice

scientific article published on 08 January 2019

High-protein formulas: evidence for use in preterm infants

scientific article published on 14 April 2014

Hypoglycemia in newborn infants: Features associated with adverse outcomes

scientific article

Impact of placental insufficiency on fetal skeletal muscle growth

scientific article published on 15 March 2016

Increased Hepatic Glucose Production in Fetal Sheep With Intrauterine Growth Restriction Is Not Suppressed by Insulin ⬇️

scientific article published on August 28, 2012

Increased adrenergic signaling is responsible for decreased glucose-stimulated insulin secretion in the chronically hyperinsulinemic ovine fetus

scientific article

Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase β-cell mass in fetal sheep

scientific article published on 4 December 2012

Increased fetal insulin concentrations for one week fail to improve insulin secretion or β-cell mass in fetal sheep with chronically reduced glucose supply

scientific article published on 7 November 2012

Increased fetal myocardial sensitivity to insulin-stimulated glucose metabolism during ovine fetal growth restriction

scientific article published on 11 February 2016

Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction.

scientific article published on 25 September 2007

Insulin is required for amino acid stimulation of dual pathways for translational control in skeletal muscle in the late-gestation ovine fetus

scientific article published on 21 October 2008

Insulin-like growth factor and fibroblast growth factor expression profiles in growth-restricted fetal sheep pancreas.

scientific article

Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle

scientific article published on 02 April 2009

Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1.

scientific article published on 5 August 2016

Knowledge gaps and research needs for understanding and treating neonatal hypoglycemia: workshop report from Eunice Kennedy Shriver National Institute of Child Health and Human Development

scientific article

Limited capacity for glucose oxidation in fetal sheep with intrauterine growth restriction

scientific article

Localisation of glucose transport in the ruminant placenta: implications for sequential use of transporter isoforms.

scientific article published on 8 December 2004

Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice

scientific article

Modern Management of Preterm Infants Prevents Adverse Developmental Outcomes From Hypoglycemia

scientific article published on 4 November 2016

Myoblast replication is reduced in the IUGR fetus despite maintained proliferative capacity in vitro

scientific article published on 4 January 2017

Neonatal Hyperglycemia-Causes, Treatments, and Cautions

scientific article published on 09 May 2018

Neonatal hypoglycemia--answers, but more questions

scientific article published on 17 July 2012

New approaches to management of neonatal hypoglycemia

scientific article

Ontogeny and insulin regulation of fetal ovine white adipose tissue leptin expression

scientific article published in February 2002

Pancreatic islet hepatocyte growth factor and vascular endothelial growth factor A signaling in growth restricted fetuses

scientific article published on 25 January 2016

Placental insufficiency decreases pancreatic vascularity and disrupts hepatocyte growth factor signaling in the pancreatic islet endothelial cell in fetal sheep

scientific article

Postnatal β2 adrenergic treatment improves insulin sensitivity in lambs with IUGR but not persistent defects in pancreatic islets or skeletal muscle

scientific article published on 29 November 2019

Prolonged Prepregnant Maternal High-Fat Feeding Reduces Fetal and Neonatal Blood Glucose Concentrations by Enhancing Fetal β-Cell Development in C57BL/6 Mice

scientific article published on 24 May 2019

Prolonged amino acid infusion into intrauterine growth-restricted fetal sheep increases leucine oxidation rates

scientific article published on 11 September 2018

Prolonged maternal amino acid infusion in late-gestation pregnant sheep increases fetal amino acid oxidation

scientific article published on 14 July 2009

Rates of myogenesis and myofiber numbers are reduced in late gestation IUGR fetal sheep

scientific article published on 01 November 2019

Reductions in insulin concentrations and β-cell mass precede growth restriction in sheep fetuses with placental insufficiency

scientific article published on 31 December 2012

Role of placental insufficiency and intrauterine growth restriction on the activation of fetal hepatic glucose production

scientific article published on 23 December 2015

Skeletal muscle amino acid uptake is lower and alanine production is greater in late gestation intrauterine growth restricted fetal sheep hindlimb

scientific article published on 04 September 2019

Skeletal muscle protein accretion rates and hindlimb growth are reduced in late gestation intrauterine growth-restricted fetal sheep.

scientific article

Sustained hypoxemia in late gestation potentiates hepatic gluconeogenic gene expression but does not activate glucose production in the ovine fetus

scientific article published on 09 April 2019

The Intrauterine Growth Restriction Phenotype: Fetal Adaptations and Potential Implications for Later Life Insulin Resistance and Diabetes ⬇️

scientific article published on June 27, 2011

The Regulatory Effects of Brown Adipose Tissue Thermogenesis on Maternal Metabolic Adaptation, Placental Efficiency, and Fetal Growth in Mice

article

The importance of using local populations to assess fetal and preterm infant growth

scientific article published in 2021

The nutritional dilemma for preterm infants: how to promote neurocognitive development and linear growth, but reduce the risk of obesity

scientific article

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