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List of works by Frank Rösch

18F-labeling and evaluation of novel MDL 100907 derivatives as potential 5-HT2A antagonists for molecular imaging

scientific article published on 8 April 2010

72/74As-labeling of HPMA based polymers for long-term in vivo PET imaging

scientific article published on 25 July 2010

AAZTA5/AAZTA5-TOC: synthesis and radiochemical evaluation with 68Ga, 44Sc and 177Lu

scientific article published on 01 August 2019

Activation of P-glycoprotein (Pgp)-mediated drug efflux by extracellular acidosis: in vivo imaging with 68Ga-labelled PET tracer

scientific article

An approach to the evaluation of the activity of the DNA repair enzyme O6-methylguanine-DNA-methyl-transferase in tumor tissue in vivo: syntheses of 6-benzyloxy-9-(2-[18F]fluoroethyl)-9H-purin-2-yl-amine and 6-benzyloxy-7-(2-[18F]fluoroethyl)-7H-pur

scientific article published in March 2002

Assessing p-Glycoprotein (Pgp) Activity In Vivo Utilizing 68Ga–Schiff Base Complexes ⬇️

scientific article published on October 1, 2011

Association of low striatal dopamine d2 receptor availability with nicotine dependence similar to that seen with other drugs of abuse

scientific article

Asymmetry in dopamine D(2/3) receptors of caudate nucleus is lost with age.

scientific article published on 15 December 2006

Automated synthesis and purification of [18F]fluoro-[di-deutero]methyl tosylate

scientific article

Brain and plasma pharmacokinetics of aripiprazole in patients with schizophrenia: an [18F]fallypride PET study

scientific article

Characterization of the serotonin 2A receptor selective PET tracer (R)-[18F]MH.MZ in the human brain

scientific article published on 12 October 2019

Clinical Translation and First In-Human Use of [44Sc]Sc-PSMA-617 for PET Imaging of Metastasized Castrate-Resistant Prostate Cancer

scientific article

Comparison Study of Two Differently Clicked 18F-Folates-Lipophilicity Plays a Key Role

scientific article published on 17 March 2018

Comparison of Linear and Hyperbranched Polyether Lipids for Liposome Shielding by 18F-Radiolabeling and Positron Emission Tomography

scientific article published on 16 April 2018

Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving

scientific article published in October 2004

Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients.

scientific article published in August 2005

Decreased dopamine D2/D3-receptor binding in temporal lobe epilepsy: an [18F]fallypride PET study

scientific article published in August 2006

Direct radiofluorination of [18F]MH.MZ for 5-HT2A receptor molecular imaging with PET

scholarly article by Matthias M. Herth et al published July 2012 in Journal of Labelled Compounds and Radiopharmaceuticals

Dopamine D2/3 receptor occupancy by quetiapine in striatal and extrastriatal areas

scientific article published on 15 April 2010

Electron- and positron-emitting radiolanthanides for therapy: aspects of dosimetry and production

article

Equilibrium, Kinetic and Structural Properties of Gallium(III) and Some Divalent Metal Complexes Formed with the New DATAm and DATA5m Ligands.

scientific article published on 15 May 2017

Ethanol-Based Post-processing of Generator-Derived ⁶⁸Ga Toward Kit-Type Preparation of ⁶⁸Ga-Radiopharmaceuticals

scientific article published on 21 April 2014

Evaluation of P-glycoprotein (abcb1a/b) modulation of [(18)F]fallypride in MicroPET imaging studies

scientific article

Evaluation of safety and dosimetry of <sup>177</sup>Lu DOTA-ZOL for therapy of bone metastases

scientific article published on 08 January 2021

Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging

scientific article published on 28 May 2019

Fate of linear and branched polyether-lipids in vivo in comparison to their liposomal formulations by 18F-radiolabeling and positron emission tomography

scientific article published on 24 February 2015

Ga[Ga]-, In[In]-oxine: a novel strategy of radiolabeling of HPMA-based micelles

HPMA Based Amphiphilic Copolymers Mediate Central Nervous Effects of Domperidone

scientific article published on 5 April 2011

HPMA-LMA copolymer drug carriers in oncology: an in vivo PET study to assess the tumor line-specific polymer uptake and body distribution

scientific article published on 26 August 2013

High opiate receptor binding potential in the human lateral pain system

scientific article published on 7 December 2005

High striatal occupancy of D2-like dopamine receptors by amisulpride in the brain of patients with schizophrenia

scientific article

Image quality analysis of 44Sc on two preclinical PET scanners: a comparison to 68Ga

scientific article published on 12 March 2020

Imaging Nigrostriatal Dopaminergic Deficit in Holmes Tremor with 18F-PR04.MZ-PET/CT.

scientific article published in September 2015

Imaging of protein synthesis: in vitro and in vivo evaluation of (44)Sc-DOTA-puromycin.

scientific article published on February 2013

Improved Efficacy of Synthesizing *MIII-Labeled DOTA Complexes in Binary Mixtures of Water and Organic Solvents. A Combined Radio- and Physicochemical Study

scientific article published on 10 May 2018

In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D(2)-like dopamine receptors

scientific article published on 19 August 2007

In vitro and in vivo structure-property relationship of (68)Ga-labeled Schiff base derivatives for functional myocardial pet imaging

scientific article

In vivo Evaluation of [225Ac]Ac-DOTAZOL for α-Therapy of Bone Metastases

scientific article published on 01 January 2018

Inhibition of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors: comparison with nonconjugated inhibitors and effect on fotemustine and temozolomide-induced cell death

scientific article published on 13 July 2004

Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging.

scientific article published on 27 February 2018

Long-term biodistribution study of HPMA-ran-LMA copolymers in vivo by means of 131I-labeling

scientific article published on 16 December 2017

Measurement of Protein Synthesis: In Vitro Comparison of 68Ga-DOTA-Puromycin, [3H]Tyrosine, and 2-Fluoro-[3H]tyrosine ⬇️

scientific article published on January 1, 2013

Modifying the body distribution of HPMA-based copolymers by molecular weight and aggregate formation

scientific article

NODAPA-OH and NODAPA-(NCS)n: synthesis, 68Ga-radiolabelling and in vitro characterisation of novel versatile bifunctional chelators for molecular imaging

scientific article published on 18 September 2008

Net influx of plasma 6-[18F]fluoro-L-DOPA (FDOPA) to the ventral striatum correlates with prefrontal processing of affective stimuli

scientific article published in July 2006

On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion

scientific article published on 18 November 2020

Opiate-induced dopamine release is modulated by severity of alcohol dependence: an [(18)F]fallypride positron emission tomography study

scientific article published on 29 July 2011

Optimization of Labeling PSMAHBED with Ethanol-Postprocessed 68Ga and Its Quality Control Systems

scientific article published on 12 January 2017

PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: a quantitative study using radiolabeling and positron emission tomography

scientific article published on 14 August 2013

PET imaging of the impact of extracellular pH and MAP kinases on the p-glycoprotein (Pgp) activity

scientific article

Parametric mapping of binding in human brain of D2 receptor ligands of different affinities

scientific article

Pharmacokinetic evaluation of [18F]PR04.MZ for PET/CT imaging and quantification of dopamine transporters in the human brain

scientific article published on 01 December 2019

Positron emission tomography in CNS drug discovery and drug monitoring

scientific article

Predicting the in vivo release from a liposomal formulation by IVIVC and non-invasive positron emission tomography imaging

scientific article published on 8 June 2010

Preliminary in vivo and ex vivo evaluation of the 5-HT2A imaging probe [(18)F]MH.MZ.

scientific article published on 26 March 2009

Processing of generator-produced 68Ga for medical application.

scientific article published on 14 September 2007

Quantification of D2-like dopamine receptors in the human brain with 18F-desmethoxyfallypride.

scientific article

Quantitative online isolation of ⁶⁸Ge from ⁶⁸Ge/⁶⁸Ga generator eluates for purification and immediate quality control of breakthrough

scientific article published on 25 July 2013

Radioactive labeling of defined HPMA-based polymeric structures using [18F]FETos for in vivo imaging by positron emission tomography.

scientific article published on 8 May 2009

Radiolabelling and preliminary evaluation of 68Ga-tetrapyrrole derivatives as potential tracers for PET ⬇️

scientific article published on December 21, 2012

Radiolanthanides in nuclear medicine.

scientific article published on January 2004

Ratio of dopamine synthesis capacity to D2 receptor availability in ventral striatum correlates with central processing of affective stimuli

scientific article

Selective binding to monoamine oxidase A: in vitro and in vivo evaluation of (18)F-labeled β-carboline derivatives

scientific article published on 8 December 2014

Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone).

scientific article published on December 2008

Structural combination of established 5-HT(2A) receptor ligands: new aspects of the binding mode

scientific article published on 15 July 2010

Structure-function evaluation of imidazopyridine derivatives selective for δ subunit containing γ-aminobutyric acid type A (GABAA) receptors

scientific article published on 16 February 2018

Surrogate markers for cerebral blood flow correlate with [¹⁸F]-fallypride binding potential at dopamine D(2/3) receptors in human striatum.

scientific article published on 12 January 2013

Synthesis and evaluation of 5,7-dichloro-4-(3-{4-[4-(2-[18F]fluoroethyl)-piperazin-1-yl]-phenyl}-ureido)-1,2,3,4-tetrahydroquinoline-2-carboxylic acid as a potential NMDA ligand to study glutamatergic neurotransmission in vivo

Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET.

scientific article

Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repaglinide): a potential beta-cell imaging agent

scientific article published in October 2004

Synthesis and preliminary evaluation of (R,R)(S,S) 5-(2-(2-[4-(2-[(18)F]fluoroethoxy)phenyl]-1-methylethylamino)-1-hydroxyethyl)-benzene-1,3-diol ([(18)F]FEFE) for the in vivo visualisation and quantification of the beta2-adrenergic receptor status

scientific article published on 01 August 2003

Synthesis of 131I-labeled glucose-conjugated inhibitors of O6-methylguanine-DNA methyltransferase (MGMT) and comparison with nonconjugated inhibitors as potential tools for in vivo MGMT imaging

scientific article published in January 2006

Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators

scientific article published on 29 July 2020

The applicability of SRTM in [18F]fallypride PET investigations: Impact of scan durations ⬇️

scientific article published on May 18, 2011

The dopamine D2 receptor ligand 18F-desmethoxyfallypride: an appropriate fluorinated PET tracer for the differential diagnosis of parkinsonism

scientific article published on 23 March 2004

The striatal and extrastriatal D2/D3 receptor-binding profile of clozapine in patients with schizophrenia

scientific article published in May 2006

Total synthesis and evaluation of [18F]MHMZ.

scientific article

Vulnerability to psychotogenic effects of ketamine is associated with elevated D2/3-receptor availability

scientific article

[(11)C]PR04.MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient (11)C-O-methylation and initial small animal PET studies.

scientific article

[18F]PR04.MZ PET/CT Imaging for Evaluation of Nigrostriatal Neuron Integrity in Patients With Parkinson Disease

scientific article published on 14 December 2020

[68Ga]Ga-DATA5m-LM4, a PET Radiotracer in the Diagnosis of SST2R-Positive Tumors: Preclinical and First Clinical Results

scientific article published on 23 November 2022

⁶⁸Ge content quality control of ⁶⁸Ge/⁶⁸Ga-generator eluates and ⁶⁸Ga radiopharmaceuticals--a protocol for determining the ⁶⁸Ge content using thin-layer chromatography

scientific article

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