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List of works by Lecia V Sequist

24-Month Overall Survival From KEYNOTE-021 Cohort G: Pemetrexed and Carboplatin With or Without Pembrolizumab As First-Line Therapy for Advanced Nonsquamous Non-Small-Cell Lung Cancer

article by Hossein Borghaei et al published 20 August 2018 in Journal of Thoracic Oncology

A Digital RNA Signature of Circulating Tumor Cells Predicting Early Therapeutic Response in Localized and Metastatic Breast Cancer

scientific article published on 13 August 2018

A Highly Sensitive and Quantitative Test Platform for Detection of NSCLC EGFR Mutations in Urine and Plasma

scientific article

A New BATTLE in the Evolving War on Cancer ⬇️

scientific article published on 01 June 2011

A Phase I Study of Erlotinib and Hydroxychloroquine in Advanced Non–Small-Cell Lung Cancer ⬇️

scientific article published on October 1, 2012

A Th1/IFNγ Gene Signature Is Prognostic in the Adjuvant Setting of Resectable High-Risk Melanoma but Not in Non-Small Cell Lung Cancer

scientific article published on 15 November 2019

A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer

scientific article published on 03 April 2013

A phase II study of oxaliplatin, pemetrexed, and bevacizumab in previously treated advanced non-small cell lung cancer

scientific article published in October 2008

A rapid outcomes ascertainment system improves the quality of prognostic and pharmacogenetic outcomes from observational studies

scientific article published in January 2008

AJRCCM: 100-Year Anniversary. The Shifting Landscape for Lung Cancer: Past, Present, and Future

scientific article

Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity

scientific article published on 01 June 2019

Acquired Resistance to Crizotinib in NSCLC with MET Exon 14 Skipping

scientific article published on 22 June 2016

Acquired Resistance to First-Line Afatinib and the Challenges of Prearranged Progression Biopsies

scientific article published on 20 August 2016

Acquired resistance to TKIs in solid tumours: learning from lung cancer

scientific article published on July 2014

Activity of IPI-504, a Novel Heat-Shock Protein 90 Inhibitor, in Patients With Molecularly Defined Non–Small-Cell Lung Cancer ⬇️

scientific article published on October 12, 2010

Adjuvant molecularly targeted therapy-epidermal growth factor tyrosine kinase inhibition and beyond

scientific article published on October 2013

Advanced Non-Small Cell Lung Cancer: Sequencing Agents in the EGFR-Mutated/ALK-Rearranged Populations

scientific article published on 01 January 2019

Afatinib Therapy: Practical Management of Adverse Events With an Oral Agent for Non-Small Cell Lung Cancer Treatment

scientific article published on 01 October 2018

Afatinib as First-line Treatment of Older Patients With EGFR Mutation-Positive Non-Small-Cell Lung Cancer: Subgroup Analyses of the LUX-Lung 3, LUX-Lung 6, and LUX-Lung 7 Trials.

scientific article published on 17 March 2018

Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-Lung 2): a phase 2 trial ⬇️

scientific article published on March 26, 2012

Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials

scientific article

Aggressive treatment for the fit elderly with non-small-cell lung cancer? Yes!

scientific article published on 21 July 2003

Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers

scientific article

An RNA-Based Digital Circulating Tumor Cell Signature Is Predictive of Drug Response and Early Dissemination in Prostate Cancer

scientific article published on 4 January 2018

An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma.

scientific article published on 17 January 2017

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

scientific article

Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer.

scientific article

Assessing the roles of EGFR gene copy number, protein expression and mutation in predicting outcomes in non-small-cell lung cancer after treatment with EGFR inhibitors

scientific article published in June 2007

Assessment of EGFR Mutation Status in Matched Plasma and Tumor Tissue of NSCLC Patients from a Phase I Study of Rociletinib (CO-1686).

scientific article published on 8 January 2016

Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia

scientific article published on 30 August 2005

BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.

scientific article published on 22 July 2011

Biodegradable nano-films for capture and non-invasive release of circulating tumor cells.

scientific article published on 20 June 2015

Brain tumor cells in circulation are enriched for mesenchymal gene expression

scientific article

Brief Report: Long-Term Overall Survival From KEYNOTE-021 Cohort G: Pemetrexed and Carboplatin With or Without Pembrolizumab as First-Line Therapy for Advanced Nonsquamous Non-Small-Cell Lung Cancer

scientific article published on 28 September 2020

Brief Report: Phase 2 Study of the HSP-90 inhibitor AUY922 in Previously Treated and Molecularly Defined Patients with Advanced Non-Small Cell Lung Cancer.

scientific article published on 13 December 2017

Brief report of biweekly pemetrexed and gemcitabine in elderly patients with non-small cell lung cancer

scientific article published in September 2009

COVID-19 Infection in a Lung Cancer Patient Population: Incidence, Presentation and Alternative Diagnostic Considerations

scientific article published on 12 November 2020

Can CT radiomic analysis in NSCLC predict histology and EGFR mutation status?

Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study.

scientific article

Case records of the Massachusetts General Hospital. Case 17-2015. A 44-year-old woman with intractable pain due to metastatic lung cancer.

scientific article

Case records of the Massachusetts General Hospital. Case 23-2008. A 26-year-old man with back pain and a mass in the lung

scientific article published in July 2008

Case records of the Massachusetts General Hospital. Case 31-2011. A 55-year-old man with oligometastatic lung cancer

scientific article published on October 13, 2011

Cetuximab Monotherapy in Patients with Advanced Non-small Cell Lung Cancer After Prior Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy ⬇️

scientific article published on November 1, 2010

Characteristics of lung cancers harboring NRAS mutations

scientific article (publication date: May 2013)

Chemotherapy with Erlotinib or chemotherapy alone in advanced non-small cell lung cancer with acquired resistance to EGFR tyrosine kinase inhibitors

scientific article published on 26 September 2013

Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.

scientific article published on 10 June 2016

Circulating tumour cells-monitoring treatment response in prostate cancer

scientific article published on 13 May 2014

Clinical Activity of Alectinib in Advanced RET-Rearranged Non-Small Cell Lung Cancer.

scientific article

Clinical Utility of Rapid Genotyping in Advanced Lung Cancer

scientific article published on 24 July 2018

Clinical activity of afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung 6.

scientific article published on 04 June 2015

Clinical and Imaging Features of Non-Small-Cell Lung Cancer in Young Patients

scientific article published on 21 October 2020

Clinicopathologic Features of NSCLC Diagnosed During Pregnancy or the Peripartum Period in the Era of Molecular Genotyping

scientific article published on 10 June 2016

Clinicopathologic and Longitudinal Imaging Features of Lung Cancer Associated with Cystic Airspaces: A Systematic Review and Meta-Analysis

scientific article published on 29 July 2020

Clinicopathologic features and outcomes of patients with lung adenocarcinomas harboring BRAF mutations in the Lung Cancer Mutation Consortium

scientific article

Clonal Evolution and the Role of Serial Liquid Biopsies in a Case of Small-Cell Lung Cancer-Transformed EGFR Mutant Non-Small-Cell Lung Cancer

scientific article published on 07 November 2017

Combination Olaparib and Temozolomide in Relapsed Small-Cell Lung Cancer

scientific article published on 15 August 2019

Complex Role of Histone Deacetylase Inhibitors in the Treatment of Non–Small-Cell Lung Cancer ⬇️

scientific article published on April 16, 2012

Computed Tomography Imaging Features and Distribution of Metastases in ROS1-rearranged Non-Small-cell Lung Cancer

scientific article published on 16 October 2019

Continued EGFR Inhibition With Postprogression Chemotherapy: Where Do We Stand?

scientific article

Correction: EGFR Exon 20 Insertion Mutations Display Sensitivity to Hsp90 Inhibition in Preclinical Models and Lung Adenocarcinomas

scientific article published on 01 May 2020

Corrigendum: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients

scientific article published on 14 November 2016

Delay of treatment change after objective progression on first-line erlotinib in epidermal growth factor receptor-mutant lung cancer

scientific article published on 15 April 2015

Depression, inflammation, and epidermal growth factor receptor (EGFR) status in metastatic non-small cell lung cancer: A pilot study.

scientific article published on 12 May 2017

Depression, survival, and epidermal growth factor receptor genotypes in patients with metastatic non-small cell lung cancer ⬇️

scientific article published on February 11, 2013

Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses

scientific article published on 7 October 2015

Detection of impaired homologous recombination repair in NSCLC cells and tissues.

scientific article published in March 2013

Diffuse Lung Metastases in EGFR-Mutant Non-Small Cell Lung Cancer

scientific article published on 13 September 2019

Does EGFR Mutation Type Influence Patient-Reported Outcomes in Patients with Advanced EGFR Mutation-Positive Non-Small-Cell Lung Cancer? Analysis of Two Large, Phase III Studies Comparing Afatinib with Chemotherapy (LUX-Lung 3 and LUX-Lung 6).

scientific article published on 24 November 2017

Dramatic Response to Combination Erlotinib and Crizotinib in a Patient with Advanced, EGFR-Mutant Lung Cancer Harboring De Novo MET Amplification

scientific article

EGFR Exon 20 Insertion Mutations Display Sensitivity to Hsp90 Inhibition in Preclinical Models and Lung Adenocarcinomas

scientific article published on 28 August 2018

EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer: A Retrospective Analysis.

scientific article published on 25 May 2016

EGFR mutation detection in circulating cell-free DNA of lung adenocarcinoma patients: analysis of LUX-Lung 3 and 6.

scientific article published on 22 December 2016

EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer

scientific article

EGFR tyrosine kinase inhibitors in lung cancer: an evolving story

scientific article published on January 2008

EGFR-Mutant Adenocarcinomas That Transform to Small-Cell Lung Cancer and Other Neuroendocrine Carcinomas: Clinical Outcomes

scientific article published on 14 December 2018

EGFR-activating mutations correlate with a Fanconi anemia-like cellular phenotype that includes PARP inhibitor sensitivity

scientific article published on 21 August 2013

Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib

scientific article

Emerging Treatment Paradigms for EGFR-Mutant Lung Cancers Progressing on Osimertinib: A Review

scientific article published on 18 June 2020

End-of-Life Care in Patients with Metastatic Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations

scientific article published on 14 September 2016

Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.

scientific article published on 12 January 2018

Epidermal Growth Factor Receptor-Mutant Lung Cancer: New Drugs, New Resistance Mechanisms, and Future Treatment Options

scientific article published on September 2015

Epidermal growth factor receptor mutation testing in the care of lung cancer patients

scientific article published on July 2006

Epidermal growth factor receptor mutations in non-small cell lung cancer: predicting clinical response to kinase inhibitors

scientific article published in August 2005

Epidermal growth factor receptor tyrosine kinase inhibitors and depression.

scientific article published on 13 July 2009

Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM.

scientific article published on 19 October 2017

Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansi

scientific article published on 21 November 2016

Exciting New Targets in Lung Cancer Therapy: ALK, IGF-1R, HDAC, and Hh ⬇️

scientific article published on June 1, 2010

Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib

scientific article

Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in KRAS-Mutant Non-Small Cell Lung Cancer

scientific article published on 25 September 2018

Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination.

scientific article published on 09 February 2017

FGFR1 Amplification in Squamous Cell Carcinoma of The Lung ⬇️

scientific article published on December 1, 2012

First-Line Afatinib versus Chemotherapy in Patients with Non-Small Cell Lung Cancer and Common Epidermal Growth Factor Receptor Gene Mutations and Brain Metastases.

scientific article published on 20 January 2016

First-generation epidermal growth factor receptor tyrosine kinase inhibitors in EGFR mutation: positive non-small cell lung cancer patients

article by Lecia V Sequist published 1 June 2008 in Journal of Thoracic Oncology

First-line afatinib for advanced EGFRm+ NSCLC: Analysis of long-term responders in the LUX-Lung 3, 6, and 7 trials

scientific article published on 08 April 2019

First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations

scientific article published on 5 May 2008

First-line use of EGFR tyrosine kinase inhibitors in patients with NSCLC containing EGFR mutations.

scientific article published on February 2010

Five-Year Follow-Up of Nivolumab in Previously Treated Advanced Non-Small-Cell Lung Cancer: Results From the CA209-003 Study

scientific article published on 23 March 2018

Genetic Changes in Squamous Cell Lung Cancer: A Review ⬇️

scientific article published on May 1, 2012

Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts.

scientific article published on 26 February 2018

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

scientific article

Genotyping lung cancer is an investment in the future

scientific article published on 8 September 2014

Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor

scientific article published on May 2015

Heterogeneity and Coexistence of T790M and T790 Wild-Type Resistant Subclones Drive Mixed Response to Third-Generation Epidermal Growth Factor Receptor Inhibitors in Lung Cancer

scientific article published on 16 July 2018

Imaging Features and Metastatic Patterns of Advanced ALK-Rearranged Non-Small Cell Lung Cancer

scientific article published on 30 December 2019

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials

scientific article

Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer

scientific article

Increased Hepatotoxicity Associated with Sequential Immune Checkpoint Inhibitor and Crizotinib Therapy in Patients with Non-Small Cell Lung Cancer

scientific article published on 08 September 2018

Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells.

scientific article published on April 2013

Integrated, Multidisciplinary Management of Pulmonary Nodules Can Streamline Care and Improve Adherence to Recommendations

scientific article published on 26 December 2019

Integrating genomic features for non-invasive early lung cancer detection

scientific article published on 25 March 2020

Integration of Stereotactic Body Radiation Therapy With Tyrosine Kinase Inhibitors in Stage IV Oncogene-Driven Lung Cancer

scientific article published on 27 June 2016

Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer

scientific article

Isolation and molecular characterization of circulating melanoma cells

scientific article

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip

scientific article

Isolation of rare circulating tumour cells in cancer patients by microchip technology

scientific article

Landscape of Acquired Resistance to Osimertinib in EGFR-Mutant NSCLC and Clinical Validation of Combined EGFR and RET Inhibition with Osimertinib and BLU-667 for Acquired RET Fusion

scientific article published on 26 September 2018

Lipodermatosclerosis secondary to pemetrexed use

scientific article published on 01 March 2015

Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLC

article

Long-term safety and survival with gefitinib in select patients with advanced non-small cell lung cancer: Results from the US IRESSA Clinical Access Program (ICAP).

scientific article

Lung Screening Benefits and Challenges: A Review of The Data and Outline for Implementation

scientific article published on 11 November 2020

Lung cancer screening

scientific article published on 01 February 2012

Lung cancer screening, version 1.2015: featured updates to the NCCN guidelines

scientific article published in January 2015

Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.

scientific article

Marked Differences in CNS Activity among EGFR Inhibitors: Case Report and Mini-Review

scientific article

Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers ⬇️

scientific article published on January 25, 2012

Microfluidic isolation of platelet-covered circulating tumor cells.

scientific article published on 21 September 2017

Modeling Resistance and Recurrence Patterns of Combined Targeted- Chemoradiotherapy Predicts Benefit of Shorter Induction Period

scientific article published on 09 September 2020

Modulation of Biomarker Expression by Osimertinib: Results of the Paired Tumor Biopsy Cohorts of the AURA Phase I Trial

scientific article published on 24 July 2017

Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer

scientific article published on 18 July 2016

Molecular analysis-based treatment strategies for the management of non-small cell lung cancer

scientific article published on September 2009

Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer

scientific article published on February 2007

Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy

scientific article published on 16 February 2018

Molecularly targeted therapies in non-small-cell lung cancer annual update 2014

scientific article

Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells

scientific article published on 7 September 2017

Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features

scientific article

Neratinib, an irreversible pan-ErbB receptor tyrosine kinase inhibitor: results of a phase II trial in patients with advanced non-small-cell lung cancer

scientific article published on 17 May 2010

Non-small cell lung cancer in octogenarians: treatment practices and preferences

scientific article published on November 2007

Novel agents in the treatment of lung cancer: Fourth Cambridge Conference

scientific article published in August 2007

Osimertinib Responses After Disease Progression in Patients Who Had Been Receiving Rociletinib

scientific article

Osimertinib for Previously Treated Patients With Advanced EGFR T790M Mutation-Positive NSCLC: Tolerability and Diagnostic Methods From an Expanded Access Program

scientific article published on 25 May 2018

Osimertinib in Pretreated T790M-Positive Advanced Non-Small-Cell Lung Cancer: AURA Study Phase II Extension Component

scientific article

Osimertinib in patients with T790M mutation-positive, advanced non-small cell lung cancer: Long-term follow-up from a pooled analysis of 2 phase 2 studies

scientific article published on 04 December 2018

Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre, open-label, phase 1b study

scientific article published on 03 February 2020

Outcomes After Combined Modality Therapy forEGFR-Mutant and Wild-Type Locally Advanced NSCLC ⬇️

scientific article published on May 31, 2011

Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer

scientific article

P1.33: Afatinib Versus Chemotherapy for EGFR Mutation-Positive NSCLC Patients Aged ≥65 Years: Subgroup Analysis of LUX-Lung 3/6: Track: Advanced NSCLC.

scientific article published on 22 September 2016

PS01.62: Long-Term Safety and Clinical Activity of Atezolizumab Monotherapy in Metastatic NSCLC: Final Results from a Phase Ia Study: Topic: Medical Oncology

scientific article

PS01.66: Biomarker Stratification of Outcomes of Third-Generation EGFR TKI Therapy in Patients with Previously-Treated Advanced NSCLC: Topic: Medical Oncology

scientific article

Patient Preferences for Use of Archived Biospecimens from Oncology Trials When Adequacy of Informed Consent Is Unclear

scientific article published on 06 September 2019

Patient-Specific Tumor Growth Trajectories Determine Persistent and Resistant Cancer Cell Populations during Treatment with Targeted Therapies

scientific article published on 21 May 2019

Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

scientific article

Pattern of Failure Analysis in Metastatic EGFR-Mutant Lung Cancer Treated with Tyrosine Kinase Inhibitors to Identify Candidates for Consolidation Stereotactic Body Radiation Therapy

scientific article

Pembrolizumab and platinum-based chemotherapy as first-line therapy for advanced non-small-cell lung cancer: Phase 1 cohorts from the KEYNOTE-021 study

scientific article published on 25 August 2018

Pembrolizumab in combination with ipilimumab as second-line or later therapy for advanced non-small-cell lung cancer: KEYNOTE-021 cohorts D and H

scientific article published on 17 December 2018

Phase 1-2a multicenter dose-ranging study of canfosfamide in combination with carboplatin and paclitaxel as first-line therapy for patients with advanced non-small cell lung cancer

scientific article published in November 2009

Phase I/II Study of AT-101 with Topotecan in Relapsed and Refractory Small Cell Lung Cancer ⬇️

scientific article published on October 1, 2010

Phase III Multinational, Randomized, Double-Blind, Placebo-Controlled Study of Tivantinib (ARQ 197) Plus Erlotinib Versus Erlotinib Alone in Previously Treated Patients With Locally Advanced or Metastatic Nonsquamous Non-Small-Cell Lung Cancer.

scientific article published on 13 July 2015

Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations.

scientific article

Phase Ib Study of High-dose Intermittent Afatinib in Patients With Advanced Solid Tumors.

scientific article

Plasma T790M Result Alters Treatment Options in a Previously T790 Wild-Type EGFR-Mutant Lung Cancer

scientific article

Predicting malignant potential of subsolid nodules: can radiomics preempt longitudinal follow up CT?

scientific article published on 10 June 2019

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

scientific article

Primary Patient-Derived Cancer Cells and Their Potential for Personalized Cancer Patient Care

scientific article published in December 2017

Protein degradation/chaperone system and histone deacetylase pathway

scientific article published on 01 November 2009

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

scientific article

RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies

scientific article published on 24 January 2020

RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis ⬇️

scientific article published on July 26, 2012

RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance.

scientific article

ROS1-targeted therapy in non-small cell lung cancer

scientific article published on December 1, 2012

Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway

scientific article published on 15 February 2017

Randomized Phase II Trial of Seribantumab in Combination with Erlotinib in Patients with EGFR Wild-Type Non-Small Cell Lung Cancer

scientific article published on 11 April 2019

Randomized phase 2 study of tivantinib plus erlotinib versus single-agent chemotherapy in previously treated KRAS mutant advanced non-small cell lung cancer.

scientific article published on 3 February 2018

Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer.

scientific article published on 18 July 2011

Randomized, double-blind, placebo-controlled, multicenter phase II study of the efficacy and safety of apricoxib in combination with either docetaxel or pemetrexed in patients with biomarker-selected non-small-cell lung cancer

scientific article published on December 2014

Rapid Onset of Retinal Toxicity From High-Dose Hydroxychloroquine Given for Cancer Therapy

scientific article

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

scientific article published on May 2010

Rationale and design of MARQUEE: a phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer

scientific article published on 21 March 2012

Reduced Erlotinib sensitivity of epidermal growth factor receptor-mutant non-small cell lung cancer following cisplatin exposure: a cell culture model of second-line erlotinib treatment

scientific article

Reply to E.R. Haspinger et al.

scientific article

Reply to F. De Marinis et al.

scientific article

Response to Osimertinib in an EGFR Exon 20 Insertion-Positive Lung Adenocarcinoma

scientific article published on 01 October 2018

Response to the Combination of Osimertinib and Trametinib in a Patient With EGFR-Mutant NSCLC Harboring an Acquired BRAF Fusion

scientific article published on 01 October 2019

Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing

scientific article published on 01 January 2007

Rociletinib in EGFR-mutated non-small-cell lung cancer

scientific article

Role of 18F-Fluorodeoxyglucose Positron Emission Tomography in Predicting Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer ⬇️

scientific article published on February 21, 2011

Role of Epidermal Growth Factor Receptor (EGFR) Inhibitors and Radiation in the Management of Brain Metastases from EGFR Mutant Lung Cancers.

scientific article

SELECT: A Phase II Trial of Adjuvant Erlotinib in Patients With Resected Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer.

scientific article published on 16 November 2018

Safety and Success of Repeat Lung Needle Biopsies in Patients with Epidermal Growth Factor Receptor-Mutant Lung Cancer

scientific article published on 31 May 2019

Safety and clinical activity of atezolizumab monotherapy in metastatic non-small-cell lung cancer: final results from a phase I study

scientific article published on 01 August 2018

Safety and efficacy of nazartinib (EGF816) in adults with EGFR-mutant non-small-cell lung carcinoma: a multicentre, open-label, phase 1 study

scientific article published on 15 January 2020

Scientific Advances in Thoracic Oncology 2016.

scientific article published on 27 May 2017

Second-generation epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer

scientific article published on March 2007

Significance of targeted therapy and genetic alterations in EGFR, ALK, or KRAS on survival in patients with non-small cell lung cancer treated with radiotherapy for brain metastases

scientific article

Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers

scientific article published in November 2017

Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer

scientific article

Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge Conference assessing opportunities for combination therapy

scientific article published on 01 June 2008

Summary statement: novel agents in the treatment of lung cancer: advances in epidermal growth factor receptor-targeted agents

scientific article

Symptom control and quality of life in LUX-Lung 3: a phase III study of afatinib or cisplatin/pemetrexed in patients with advanced lung adenocarcinoma with EGFR mutations

scientific article

TG4010 immunotherapy combined with first-line therapy in advanced non-small cell lung cancer (NSCLC): phase IIb results of the TIME study.

scientific article

Tackling the Next Generation of Resistance in EGFR-Mutant Lung Cancer

scientific article

Targeted therapies: optimal first-line therapy for NSCLC with EGFR mutations

scientific article published in February 2010

Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer

scientific article published on 19 July 2019

The Allelic Context of the C797S Mutation Acquired upon Treatment with Third-Generation EGFR Inhibitors Impacts Sensitivity to Subsequent Treatment Strategies

scientific article

The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients

scientific article published on March 2009

The Impact of EGFR Mutation Status on Outcomes in Patients With Resected Stage I Non-Small Cell Lung Cancers ⬇️

scientific article published on August 8, 2013

The Impact of Smoking and TP53 mutations in lung adenocarcinoma patients with targetable mutations - the Lung Cancer Mutation Consortium (LCMC2).

scientific article published on 7 December 2017

The Role of Liquid Biopsies in Lung Cancer Screening

scientific article published on 03 June 2017

The Value of Early Depth of Response in Predicting Long-Term Outcome in EGFR-Mutant Lung Cancer

scientific article

The anticipated next season of EGFR inhibitors

scientific article published on 20 March 2015

The role of third-generation epithelial growth factor receptor inhibitors in non-small cell lung cancer.

scientific article published in March 2015

Timing of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Patients With Lung Cancer With EGFR Mutations ⬇️

scientific article published on 02 July 2012

Toward noninvasive genomic screening of lung cancer patients.

scientific article published on 4 May 2009

Tracking the Evolution of Resistance to ALK Tyrosine Kinase Inhibitors through Longitudinal Analysis of Circulating Tumor DNA

scientific article published on 23 January 2018

Transformation from NSCLC to SCLC: when did it happen? - Authors' reply

scientific article published in July 2015

Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin

scientific article

Treatment of EGFR-Mutant Lung Cancers After Progression in Patients Receiving First-Line EGFR Tyrosine Kinase Inhibitors : A Review

scientific article published on 19 May 2016

Treatment of advanced non-small cell lung cancer in the elderly

scientific article

Tumor Epidermal Growth Factor Receptor Genotype and Depression in Stage IV Non-Small Cell Lung Cancer ⬇️

scientific article published on January 1, 2011

Tumor Hypoxia Response After Targeted Therapy in EGFR-Mutant Non-Small Cell Lung Cancer: Proof of Concept for FMISO-PET.

scientific article

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

scientific article published on February 2016

Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells

scientific article published on 15 January 2015

Unlocking the Mystery of Small-Cell Lung Cancer Transformations in EGFR Mutant Adenocarcinoma

scientific article published on 10 July 2017

Update on epidermal growth factor receptor inhibitor development in lung cancer.

scientific article published in September 2006

Update to Rociletinib Data with the RECIST Confirmed Response Rate

scientific article published on 11 May 2016

Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs

scientific article

Volumetric Tumor Response and Progression in EGFR-mutant NSCLC Patients Treated with Erlotinib or Gefitinib

scientific article published on 8 January 2016

Whole blood stabilization for the microfluidic isolation and molecular characterization of circulating tumor cells.

scientific article published on 23 November 2017

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