List of works - Wuyuan Lu

A Hierarchical Peptide-Lanthanide Framework To Accurately Redress Intracellular Carcinogenic Protein-Protein Interaction

scientific article published on 31 October 2019

A Left-Handed Solution to Peptide Inhibition of the p53-MDM2 Interaction

scientific article

An Ultrahigh Affinity d -Peptide Antagonist Of MDM2

scientific article

Antibacterial activity and specificity of the six human {alpha}-defensins

scientific article

Apamin as a novel template for structure-based rational design of potent peptide activators of p53

scientific article

CCR6 ligands inhibit HIV by inducing APOBEC3G.

scientific article

Chemically synthesized human survivin does not inhibit caspase-3.

scientific article published on 6 June 2008

Co-encapsulating the fusogenic peptide INF7 and molecular imaging probes in liposomes increases intracellular signal and probe retention

scientific article (publication date: 2015)

Crystal structures of human alpha-defensins HNP4, HD5, and HD6

scientific article

D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasms

scientific article

Delineation of interfaces on human alpha-defensins critical for human adenovirus and human papillomavirus inhibition

scientific article published on 4 September 2014

Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

scientific article

Effects of the terminal charges in human neutrophil alpha-defensin 2 on its bactericidal and membrane activity

scientific article

Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3

scientific article

Functional Determinants of Human Enteric -Defensin HD5: CRUCIAL ROLE FOR HYDROPHOBICITY AT DIMER INTERFACE

scientific article

Human Beta Defensin 2 Selectively Inhibits HIV-1 in Highly Permissive CCR6⁺CD4⁺ T Cells.

scientific article

Human alpha-defensins block papillomavirus infection

scholarly article

Human beta-defensins suppress human immunodeficiency virus infection: potential role in mucosal protection.

scientific article

Human defensins: synthesis and structural properties

scientific article published on January 2007

Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro

scientific article

Human -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets

scientific article

Impact of pro segments on the folding and function of human neutrophil alpha-defensins

scientific article

Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization

scientific article

Invariant gly residue is important for α-defensin folding, dimerization, and function: a case study of the human neutrophil α-defensin HNP1

scientific article

Limitations of Peptide Retro-inverso Isomerization in Molecular Mimicry

scientific article

Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin

scientific article

Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240

scientific article

Peptide-Induced Self-Assembly of Therapeutics into a Well-Defined Nanoshell with Tumor-Triggered Shape and Charge Switch

scientific article published on 21 September 2018

Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.

scientific article

Reexamination of the recognition preference of the specificity pocket of the Abl SH3 domain

scientific article

Resonance Assignment and Three-Dimensional Structure Determination of a Human α-Defensin, HNP-1, by Solid-State NMR

scientific article

Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5

scientific article

Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 function

scientific article published on 13 November 2013

Soluble factors from T cells inhibiting X4 strains of HIV are a mixture of β chemokines and RNases

scientific article

Sometimes it takes two to tango: contributions of dimerization to functions of human α-defensin HNP1 peptide

scientific article

Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37

scientific article

Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX

scientific article

Structure of the scorpion toxin BmBKTtx1 solved from single wavelength anomalous scattering of sulfur

scientific article

Structure-dependent functional properties of human defensin 5

scientific article

Structures of thymus and activation-regulated chemokine (TARC)

scientific article

Systematic Mutational Analysis of Peptide Inhibition of the p53–MDM2/MDMX Interactions

scientific article

The Membrane-Bound Structure and Topology of a Human α-Defensin Indicate a Dimer Pore Mechanism for Membrane Disruption ⬇️

scientific article published on October 26, 2010

The conserved salt bridge in human alpha-defensin 5 is required for its precursor processing and proteolytic stability

scientific article published on 22 May 2008

The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins

scientific article

Thermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensins

scientific article

Through the looking glass, mechanistic insights from enantiomeric human defensins

scientific article

Topology of the disulfide bonds in the antiviral lectin scytovirin

scientific article

Total chemical synthesis of human T-cell leukemia virus type 1 protease via native chemical ligation

scientific article

Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs

scientific article

Trp-26 imparts functional versatility to human alpha-defensin HNP1

scientific article

Turning a Luffa Protein into a Self-Assembled Biodegradable Nanoplatform for Multitargeted Cancer Therapy

scientific article published on 18 October 2018

Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid II

scientific article (publication date: 2013)

List of works by Wuyuan Lu

A Hierarchical Peptide-Lanthanide Framework To Accurately Redress Intracellular Carcinogenic Protein-Protein Interaction

A Left-Handed Solution to Peptide Inhibition of the p53-MDM2 Interaction

An Ultrahigh Affinity d -Peptide Antagonist Of MDM2

Antibacterial activity and specificity of the six human {alpha}-defensins

Apamin as a novel template for structure-based rational design of potent peptide activators of p53

CCR6 ligands inhibit HIV by inducing APOBEC3G.

Chemically synthesized human survivin does not inhibit caspase-3.

Co-encapsulating the fusogenic peptide INF7 and molecular imaging probes in liposomes increases intracellular signal and probe retention

Crystal structures of human alpha-defensins HNP4, HD5, and HD6

D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasms

Delineation of interfaces on human alpha-defensins critical for human adenovirus and human papillomavirus inhibition

Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

Effects of the terminal charges in human neutrophil alpha-defensin 2 on its bactericidal and membrane activity

Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3

Functional Determinants of Human Enteric -Defensin HD5: CRUCIAL ROLE FOR HYDROPHOBICITY AT DIMER INTERFACE

Human Beta Defensin 2 Selectively Inhibits HIV-1 in Highly Permissive CCR6⁺CD4⁺ T Cells.

Human alpha-defensins block papillomavirus infection

Human beta-defensins suppress human immunodeficiency virus infection: potential role in mucosal protection.

Human defensins: synthesis and structural properties

Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro

Human -Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets

Impact of pro segments on the folding and function of human neutrophil alpha-defensins

Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization

Invariant gly residue is important for α-defensin folding, dimerization, and function: a case study of the human neutrophil α-defensin HNP1

Limitations of Peptide Retro-inverso Isomerization in Molecular Mimicry

Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin

Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240

Peptide-Induced Self-Assembly of Therapeutics into a Well-Defined Nanoshell with Tumor-Triggered Shape and Charge Switch

Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.

Reexamination of the recognition preference of the specificity pocket of the Abl SH3 domain

Resonance Assignment and Three-Dimensional Structure Determination of a Human α-Defensin, HNP-1, by Solid-State NMR

Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5

Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 function

Soluble factors from T cells inhibiting X4 strains of HIV are a mixture of β chemokines and RNases

Sometimes it takes two to tango: contributions of dimerization to functions of human α-defensin HNP1 peptide

Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37

Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX

Structure of the scorpion toxin BmBKTtx1 solved from single wavelength anomalous scattering of sulfur

Structure-dependent functional properties of human defensin 5

Structures of thymus and activation-regulated chemokine (TARC)

Systematic Mutational Analysis of Peptide Inhibition of the p53–MDM2/MDMX Interactions

The Membrane-Bound Structure and Topology of a Human α-Defensin Indicate a Dimer Pore Mechanism for Membrane Disruption ⬇️

The conserved salt bridge in human alpha-defensin 5 is required for its precursor processing and proteolytic stability

The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins

Thermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensins

Through the looking glass, mechanistic insights from enantiomeric human defensins

Topology of the disulfide bonds in the antiviral lectin scytovirin

Total chemical synthesis of human T-cell leukemia virus type 1 protease via native chemical ligation

Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs

Trp-26 imparts functional versatility to human alpha-defensin HNP1

Turning a Luffa Protein into a Self-Assembled Biodegradable Nanoplatform for Multitargeted Cancer Therapy

Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid II