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List of works by Shigehisa Kitano

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Immunologic correlates of the abscopal effect in a patient with melanoma

scientific article (publication date: 8 March 2012)
Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment

scientific article published on 15 December 2011
Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype

scientific article
Computational algorithm-driven evaluation of monocytic myeloid-derived suppressor cell frequency for prediction of clinical outcomes

scientific article
Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor

scientific article published on January 2014
Nivolumab for advanced melanoma: pretreatment prognostic factors and early outcome markers during therapy

scientific article published on 15 October 2016
Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients

scientific article published on October 2013
Granzyme B is a novel interleukin-18 converting enzyme

scientific article published on 17 June 2010
Humoral immune responses in patients vaccinated with 1-146 HER2 protein complexed with cholesteryl pullulan nanogel

scientific article published on 15 December 2007
HER2-specific T-cell immune responses in patients vaccinated with truncated HER2 protein complexed with nanogels of cholesteryl pullulan

scientific article published on 01 December 2006
Comparison of tumor-infiltrating lymphocytes between primary and metastatic tumors in breast cancer patients

scientific article published on 11 October 2016
Comprehensive immunohistochemical analysis of tumor microenvironment immune status in esophageal squamous cell carcinoma

scientific article published on 15 June 2016
Clinical Development of Immune Checkpoint Inhibitors

scientific article
Metabolic activity by (18)F-FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC.

scientific article
Determination of cellularly processed HLA-A2402-restricted novel CTL epitopes derived from two cancer germ line genes, MAGE-A4 and SAGE

scientific article
Antibody responses against NY-ESO-1 and HER2 antigens in patients vaccinated with combinations of cholesteryl pullulan (CHP)-NY-ESO-1 and CHP-HER2 with OK-432

scientific article published on 15 September 2009
A novel method for evaluating antibody-dependent cell-mediated cytotoxicity by flowcytometry using cryopreserved human peripheral blood mononuclear cells

scientific article published on 27 January 2016
Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.

scientific article published on 16 June 2016
Pretreatment Immune Status Correlates with Progression-Free Survival in Chemotherapy-Treated Metastatic Colorectal Cancer Patients

scientific article published on 28 April 2016
Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report

scientific article published on 21 November 2017
DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel

scientific article
Biomarkers for Immune Checkpoint Inhibitors in Melanoma

article published in 2018
High Absolute Monocyte Count Predicts Poor Clinical Outcome in Patients with Castration-Resistant Prostate Cancer Treated with Docetaxel Chemotherapy

scientific article published on 30 June 2016
Chimeric Antigen Receptor T-Cells for the Treatment of B-Cell Acute Lymphoblastic Leukemia.

scientific article published on 19 February 2018
Discovery of a Good Responder Subtype of Esophageal Squamous Cell Carcinoma with Cytotoxic T-Lymphocyte Signatures Activated by Chemoradiotherapy

scientific article published on January 1, 2015
The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy

scientific article published on 30 May 2017
Association of antithyroglobulin antibodies with the development of thyroid dysfunction induced by nivolumab

article
CD4+ T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy

scientific article published on 23 December 2019
Markers for anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) therapy in melanoma

Tremelimumab-associated tumor regression following after initial progression: two case reports

scientific article published on 02 October 2015
Tumor-associated CD204+ M2 macrophages is an unfavorable prognosticator in uterine cervical adenocarcinoma

scientific article published on 22 December 2017
Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance

scientific article published on 23 September 2016
Generation of peptide-specific CD8+ T cells by phytohemagglutinin-stimulated antigen-mRNA-transduced CD4+ T cells.

scientific article published on 19 June 2006
Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model

scientific article published on 19 February 2016
Infusion of donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene for recurrent hematologic malignancies after allogeneic hematopoietic stem cell transplantation

scientific article published on 7 May 2015
Approach to the Adult Acute Lymphoblastic Leukemia Patient

scientific article published on 06 August 2019
Large-scale comprehensive immunohistochemical biomarker analyses in esophageal squamous cell carcinoma

scientific article published on 29 July 2017
Elevated fibrin-related markers in patients with malignant diseases suspected of having thrombotic disorders

scientific article published on 31 July 2009
Diagnostic significance of intratumoral CD8+ tumor-infiltrating lymphocytes in medullary carcinoma

scientific article published on 6 November 2017
Immunotherapy for genitourinary tumors

scientific article published on 01 February 2019
Peripheral blood and tumor biomarkers in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab.

scientific article published on 7 November 2013
Severe colitis after PD-1 blockade with nivolumab in advanced melanoma patients: potential role of Th1-dominant immune response in immune-related adverse events: two case reports

scientific article published on 29 October 2019
Donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene: detailed immunological function following add-back after haplo-identical transplantation

scientific article
First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors

scientific article published on 24 July 2019
Relationship between the immune microenvironment of different locations in a primary tumour and clinical outcomes of oesophageal squamous cell carcinoma

scientific article published on 25 November 2019
Erratum to: Infusion of donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene for recurrent hematologic malignancies after allogeneic hematopoietic stem cell transplantation

scientific article published on October 1, 2015
Investigation of clinical factors associated with longer overall survival in advanced melanoma patients treated with sequential ipilimumab

scientific article published on 04 April 2019
Impact of low-dose anti-thymocyte globulin on immune reconstitution after allogeneic hematopoietic cell transplantation

scientific article published on 22 October 2019
Development of immune checkpoint inhibitors

scientific article published in January 2017
[Clinical Significance of Ipilimumab and the Combination Therapy as Immune Checkpoint Inhibitor]

scientific article published on 01 June 2019

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