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List of works by Andrew E Aplin

Activation of CD8+ T cells contributes to anti-tumor effects of CDK4/6 inhibitors plus MEK inhibitors

scientific article published on 13 July 2020

BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

scientific article published on 18 November 2020

In Vivo ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma

scientific article published on 03 July 2019

Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma

scientific article published on 18 March 2019

Metabolic adaptations to MEK and CDK4/6 co-targeting in uveal melanoma

scientific article published on 19 May 2020

Murine Cytomegalovirus Infection of Melanoma Lesions Delays Tumor Growth by Recruiting and Repolarizing Monocytic Phagocytes in the Tumor

scientific article published on 30 September 2019

Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis

scientific article published on 03 December 2019

PLX3397 inhibits the accumulation of intra-tumoral macrophages and improves bromodomain and extra-terminal inhibitor efficacy in melanoma

scientific article published on 11 December 2019

Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma

scientific article published on 20 January 2022

Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma

scientific article published on 01 February 2019

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

scientific article published on 16 March 2022

The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019)

scientific article published on 15 October 2020

m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.

scientific article

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